摘要:
The device (1) comprises a first snare (10) and a second snare (20), each of these snares comprising a contractable hollow elongated body (11, 21) which defines a longitudinal central axis (X10, X20) and which reduces its cross section when two opposed first (12, 22) and second (13, 23) ends thereof are axially moved away from each other. The first end (12) of the first snare (10) and the first end (22) of the second snare (20) are each open and adapted to be fitted and tightened around, respectively, two stumps (T1, T2) of a soft tissue (T) to be repaired. The second end (13) of the first snare (10) and the second end (23) of the second snare (20) are adapted to the axially pulled so that the second end of each of the two snares is passed alongside or through the body (11, 21) of the other snare.
摘要:
The present invention is directed to bioactive compositions that induce the repair of damaged or diseased connective tissues upon contact of the damaged or diseased tissues with the composition in vivo. More particularly the present invention is directed to the use of compositions comprising an effective amount of bone sialoprotein to enhance the repair of damaged or diseased bone.
摘要:
A system for suture implantation according to embodiments of the present invention includes a suture implant component including a body which extends along a longitudinal dimension, the body including an opening configured to receive a suture, the body configured for attachment to the suture, the body being deformable, upon application of a tension to the suture, between a resting configuration in which the body has a first longitudinal dimension and a first transverse dimension, and an active configuration in which the body has a second longitudinal dimension smaller than the first longitudinal dimension and a second transverse dimension larger than the first transverse dimension, and further including a wall arranged about the longitudinal dimension, wherein the wall is deformable in an accordion-like manner as the body deforms from the resting configuration to the active configuration.
摘要:
Methods for tissue repair are provided employing a matrix comprising a biocompatible, bioerodable polymer, said polymer comprising a thermoplastic lactide-containing terpolymer of monomer units derived from lactic acid, glycolic acid, and either caprolactone or valerolactone, which has a water solubility of about 0.01 to about 500 mg/mL at about 25° C. and adhesive strength of about 600 to about 150,000 Pa and applying the matrix to a tissue defect. The matrix or adhesive can further comprise a filler or a bioactive agent, or both.
摘要:
Methods for tissue repair are provided employing a matrix comprising a biocompatible, bioerodable polymer, said polymer comprising a thermoplastic lactide-containing terpolymer of monomer units derived from lactic acid, glycolic acid, and either caprolactone or valerolactone, which has a water solubility of about 0.01 to about 500 mg/mL at about 25° C. and adhesive strength of about 600 to about 150,000 Pa and applying the matrix to a tissue defect. The matrix or adhesive can further comprise a filler or a bioactive agent, or both.
摘要:
The present invention is directed to bioactive composition that induce the repair of damaged or diseased connective tissues upon contact of the damaged or diseased tissues with the composition in vivo. More particularly the present invention is directed to the use of a composition comprising an effective amount of endothelin to enhance the repair of damaged or diseased bone and cartilage tissues.
摘要:
The present invention relates to the isolation of cartilage or bone precursor cells from hematopoietic and non-hematopoietic cells and their use in bone and cartilage regeneration procedures. The precursor cells are used for in vivo bone or cartilage repair by transplanting the cells, with or without a carrier material and without the need for in vitro culturing of the cells, to sites in the body requiring bone or cartilage repair.
摘要:
A composition and method for repairing damaged connective tissue is provided. The composition comprises pseudo-poly(amino acids) and/or classic poly(amino acids) that exhibit adhesiveness for connective tissues. The composition is formed into an adhesive tissue repair implant and pressed against the damaged tissue to adhere the adhesive composition to the tissue.
摘要:
The present invention relates to a composition and method that optimizes retention of physiological activity of a biologically active compound during sterilization of said compound with gamma or electron-beam radiation. The method comprises the steps of forming a protected mixture that comprises the biologically active compound, an extraneous protein, and a free-radical scavenger, and irradiating the protected mixture with about 1 to about 3 mRad of gamma or electron-beam radiation.
摘要:
This reinforcing band (1) for restoring a soft tissue, such as a tendon or a ligament, comprises a textile component with at least one free edge (2, 4). In addition, the or each free edge is folded back into an inner volume of the textile component in such a way as to define an attachment edge (6, 8) suitable for attachment to the soft tissue.