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    Turbocharger surge management control techniques to eliminate surge valve
    1.
    发明授权
    Turbocharger surge management control techniques to eliminate surge valve 有权

    公开(公告)号：US10760479B2

    公开(公告)日：2020-09-01

    申请号：US16018960

    申请日：2018-06-26

    申请人： Ethan E Bayer ,  David R Pedro ,  David A Lawrence ,  Saikiran Chikine

    发明人： Ethan E Bayer ,  David R Pedro ,  David A Lawrence ,  Saikiran Chikine

    IPC分类号： F02B37/22 ,  F02D41/00 ,  F02M35/10 ,  F02B37/12

    摘要： A control system and method for an engine including a turbocharger without a surge valve involve utilizing one or more pressure sensors configured to measure air pressure in an intake system of the engine, the intake system comprising a compressor of the turbocharger and a throttle valve downstream from the compressor, and a controller configured to control the engine to avoid surge at the compressor and eliminate a need for the surge valve by determining a desired position for the throttle valve based on a driver requested engine torque, determining a minimum mass flow through the compressor that avoids surge based on the measured air pressure in the intake system and a predetermined compressor map, and commanding the throttle valve to a target position to maintain at least the minimum compressor mass flow, wherein the target position is greater than the desired position, thereby avoiding surge at the compressor.

    ENGINE CYLINDER BANK-TO-BANK TORQUE IMBALANCE CORRECTION
    4.
    发明申请
    ENGINE CYLINDER BANK-TO-BANK TORQUE IMBALANCE CORRECTION 有权
    发动机缸体至银行扭矩不平衡校正

    公开(公告)号：US20160076471A1

    公开(公告)日：2016-03-17

    申请号：US14851033

    申请日：2015-09-11

    申请人： Ethan E. Bayer ,  Ayman Ismail ,  David A. Lawrence

    发明人： Ethan E. Bayer ,  Ayman Ismail ,  David A. Lawrence

    IPC分类号： F02D41/00 ,  F02D13/02 ,  F02B75/22 ,  F02D41/14

    CPC分类号： F02D41/0082 ,  F01L1/34 ,  F01L2013/111 ,  F01L2800/11 ,  F01L2820/041 ,  F01L2820/042 ,  F02B75/22 ,  F02D13/0226 ,  F02D13/0238 ,  F02D41/0085 ,  F02D41/1405 ,  F02D41/1443 ,  F02D41/1454 ,  F02D41/2451 ,  F02D41/2454 ,  F02D2041/001 ,  F02D2200/0411 ,  Y02T10/18

    摘要： An engine bank-to-bank airflow balancing technique includes calculating current and offset volumetric efficiencies of the engine and calculating a slope representing (i) a difference between the offset and current volumetric efficiencies and (ii) a difference between offset and current intake camshaft positions. Based on the respective exhaust gas oxygen concentrations, the technique involves calculating a volumetric efficiency correction corresponding to each cylinder bank and based on the slope and the volumetric efficiency corrections, calculating target intake camshaft position shifts. The technique further involves controlling offsets of the intake camshafts based on the target intake camshaft position shifts. After a predetermined number of target intake camshaft position shifts are determined and stored with respect to various combinations of engine speed and a ratio of intake manifold pressure to barometric pressure, final intake camshaft position shifts may be determined and utilized when determining the intake camshaft positions.

    摘要翻译： 发动机库对空气流平衡技术包括计算发动机的当前和偏移体积效率并计算斜率，其表示（i）偏移和当前体积效率之间的差异，以及（ii）偏置和当前进气凸轮轴位置之间的差异 。 基于相应的废气氧浓度，该技术涉及计算对应于每个气缸组的体积效率校正，并且基于斜率和体积效率校正，计算目标进气凸轮轴位置偏移。 该技术还涉及基于目标进气凸轮轴位置偏移来控制进气凸轮轴的偏移。 在相对于发动机转速和进气歧管压力与大气压力的比例的各种组合来确定和存储预定数量的目标进气凸轮轴位置偏移之后，可以在确定进气凸轮轴位置时确定和利用最终进气凸轮轴位置偏移。

    POLYPEPTIDES SHARING SEQUENCE IDENTITY WITH A FIBROBLAST GROWTH FACTOR POLYPEPTIDE AND NUCLEIC ACIDS ENCODING THE SAME
    9.
    发明申请
    POLYPEPTIDES SHARING SEQUENCE IDENTITY WITH A FIBROBLAST GROWTH FACTOR POLYPEPTIDE AND NUCLEIC ACIDS ENCODING THE SAME 审中-公开
    多肽与纤维蛋白原生长因子多肽和核酸共编序列序列识别

    公开(公告)号：US20090098603A1

    公开(公告)日：2009-04-16

    申请号：US12273334

    申请日：2008-11-18

    申请人： David BOTSTEIN ,  Audrey Goddard ,  Austin L. Gurney ,  Kenneth J. Hillan ,  David A. Lawrence ,  Margaret Ann Roy

    发明人： David BOTSTEIN ,  Audrey Goddard ,  Austin L. Gurney ,  Kenneth J. Hillan ,  David A. Lawrence ,  Margaret Ann Roy

    IPC分类号： C12P21/04 ,  C12N15/11 ,  C12N15/00 ,  C12N5/06 ,  C07K14/00 ,  C12N1/21 ,  C12N1/19

    CPC分类号： C07K14/50 ,  C07K2317/24 ,  C07K2319/00

    摘要： The present invention is directed to novel polypeptides having homology to the PRO533 protein and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention, and methods for producing the polypeptides of the present invention. The invention concerns compositions and methods for the diagnosis and treatment of neoplastic cell growth and proliferation in mammals, including humans. The invention is based on the identification of genes that are amplified in the genome of tumor cells. Such gene amplification is expected to be associated with the overexpression of the gene product and contribute to tumorigenesis and/or autocrine signaling. Accordingly, the proteins encoded by the amplified genes are believed to be useful targets for the diagnosis and/or treatment (including prevention) of certain cancers, and may act of predictors of the prognosis of tumor treatment. Furthermore, the compounds, compositions including antagonists and methods of the present invention are further expected to have therapeutic effect upon conditions characterized by FgF-19 modulation.

    摘要翻译： 本发明涉及与PRO533蛋白质和编码这些多肽的核酸分子具有同源性的新型多肽。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明多肽的嵌合多肽分子，与本发明的多肽结合的抗体，以及本发明多肽的制备方法 发明。 本发明涉及用于诊断和治疗哺乳动物包括人类的肿瘤细胞生长和增殖的组合物和方法。 本发明基于在肿瘤细胞基因组中扩增的基因的鉴定。 预期这种基因扩增与基因产物的过度表达有关，并且有助于肿瘤发生和/或自分泌信号传导。 因此，由扩增的基因编码的蛋白质被认为是某些癌症的诊断和/或治疗（包括预防）的有用靶标，并且可以作为肿瘤治疗预后的预测因子。 此外，进一步预期本发明的化合物，包括拮抗剂和方法的组合物对于以FgF-19调节为特征的病症具有治疗作用。