Methods for screening for inhibitors of the transcription-enhancing
activity of the X protein of hepatitis B virus
    1.
    发明授权
    Methods for screening for inhibitors of the transcription-enhancing activity of the X protein of hepatitis B virus 失效
    筛选乙型肝炎病毒X蛋白转录增强活性抑制剂的方法

    公开(公告)号:US06051373A

    公开(公告)日:2000-04-18

    申请号:US351659

    申请日:1994-12-07

    摘要: Disclosed is a method for screening for inhibitors of Hepatitis B Virus pX activity. The method involves contacting a test compound with (I) the pX protein of HBV, (ii) a transcription factor comprising the bZIP domain, or fragments that comprise a minimal a bZIP domain, and (iii) an oligoduplex comprising a target DNA sequence of the transcription factor to form a test mixture. After incubating the test mixture under appropriate conditions and for a sufficient time to allow pX-mediated dimerization and DNA binding of the transcription factor to occur, the level of DNA binding of the transcription factor in each test mixture is determined. A test compound is considered to be any compound that causes a decrease in the level of DNA binding in the test mixture relative to the level of DNA binding in control mixtures.

    摘要翻译: 公开了筛选乙型肝炎病毒pX活性抑制剂的方法。 该方法包括使测试化合物与(I)HBV的pX蛋白质接触,(ii)包含bZIP结构域的转录因子或包含最小bZIP结构域的片段,和(iii)包含靶DNA DNA序列的寡偶联 转录因子形成试验混合物。 将试验混合物在合适的条件下孵育足够的时间以允许pX介导的二聚化和转录因子的DNA结合发生,确定每个测试混合物中转录因子的DNA结合水平。 被测化合物被认为是导致测试混合物中DNA结合水平相对于对照混合物中DNA结合水平降低的任何化合物。

    Unified user login for co-location facilities
    2.
    发明授权
    Unified user login for co-location facilities 有权
    统一用户登录协同设施

    公开(公告)号:US09082091B2

    公开(公告)日:2015-07-14

    申请号:US12964629

    申请日:2010-12-09

    IPC分类号: H04L9/32 G06Q10/06 G06F21/60

    摘要: A logical customer organization model is applied to group the individual agreements into separate logical customer organizations, wherein the groupings can be region based groupings, organization groupings and departmental groupings. Unified login identification (ID) model is applied to enable a first user to login to a portal using a first login ID to access a first asset in a first asset group according to a first logical customer organization. The unified login ID model enables the first user to use the same first login ID to access a second asset in the first asset group according to the first logical customer organization. The unified login ID model also enables the first user to login to the portal using a second login ID to access one or more assets in a second asset group according to a second logical customer organization. Each of the first and second logical customer organization may be associated with one or more asset groups and one or more user groups.

    摘要翻译: 应用逻辑客户组织模型将各个协议分组到单独的逻辑客户组织中,其中分组可以是基于区域的分组,组织分组和部门分组。 应用统一登录识别(ID)模型以使第一用户能够使用第一登录ID登录到门户,以根据第一逻辑客户组织访问第一资产组中的第一资产。 统一登录ID模型使得第一用户能够使用相同的第一登录ID来根据第一逻辑客户组织访问第一资产组中的第二资产。 统一登录ID模型还允许第一用户使用第二登录ID登录到门户,以根据第二逻辑客户组织访问第二资产组中的一个或多个资产。 第一和第二逻辑客户组织中的每一个可以与一个或多个资产组和一个或多个用户组相关联。

    PERFORMANCE, ANALYTICS AND AUDITING FRAMEWORK FOR PORTAL APPLICATIONS
    3.
    发明申请
    PERFORMANCE, ANALYTICS AND AUDITING FRAMEWORK FOR PORTAL APPLICATIONS 有权
    性能,分析和门户应用的审核框架

    公开(公告)号:US20110145399A1

    公开(公告)日:2011-06-16

    申请号:US12964677

    申请日:2010-12-09

    IPC分类号: G06F15/173

    摘要: A performance, analytics and auditing (PAA) system is configured to operate with a complex web application including a portal application and its sub systems non-intrusively. The PAA system includes a first component configured to capture behavior-related information from the portal application, a second component configured to capture performance-related information from the portal application, a third component configured to capture auditing-related information from the portal application. The PAA system is further configured to start or stop with minimal impact on the portal application, wherein the PAA system is coded using Aspect Oriented Programming (AOP) and able to collect information from multiple threads.

    摘要翻译: 性能,分析和审计(PAA)系统被配置为使用非侵入式的门户应用程序及其子系统的复杂Web应用程序进行操作。 PAA系统包括被配置为从门户应用程序捕获行为相关信息的第一组件,被配置为从门户应用程序捕获与性能相关的信息的第二组件,被配置为从门户应用程序捕获与审计相关的信息的第三组件。 PAA系统还被配置为以对门户应用程序的最小影响来启动或停止,其中PAA系统使用面向对象编程(AOP)进行编码,并能够从多个线程收集信息。

    UNIFIED USER LOGIN FOR CO-LOCATION FACILITIES
    7.
    发明申请
    UNIFIED USER LOGIN FOR CO-LOCATION FACILITIES 有权
    统一用户登录协同设施

    公开(公告)号:US20110145903A1

    公开(公告)日:2011-06-16

    申请号:US12964629

    申请日:2010-12-09

    IPC分类号: H04L9/32

    摘要: A logical customer organization model is applied to group the individual agreements into separate logical customer organizations, wherein the groupings can be region based groupings, organization groupings and departmental groupings. Unified login identification (ID) model is applied to enable a first user to login to a portal using a first login ID to access a first asset in a first asset group according to a first logical customer organization. The unified login ID model enables the first user to use the same first login ID to access a second asset in the first asset group according to the first logical customer organization. The unified login ID model also enables the first user to login to the portal using a second login ID to access one or more assets in a second asset group according to a second logical customer organization. Each of the first and second logical customer organization may be associated with one or more asset groups and one or more user groups.

    摘要翻译: 应用逻辑客户组织模型将各个协议分组到单独的逻辑客户组织中,其中分组可以是基于区域的分组,组织分组和部门分组。 应用统一登录识别(ID)模型以使第一用户能够使用第一登录ID登录到门户,以根据第一逻辑客户组织访问第一资产组中的第一资产。 统一登录ID模型使得第一用户能够使用相同的第一登录ID来根据第一逻辑客户组织访问第一资产组中的第二资产。 统一登录ID模型还允许第一用户使用第二登录ID登录到门户,以根据第二逻辑客户组织访问第二资产组中的一个或多个资产。 第一和第二逻辑客户组织中的每一个可以与一个或多个资产组和一个或多个用户组相关联。