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47 条记录 (耗时 0.11 秒)

    Human protein kinase, phosphatase, and protease family members and uses thereof
    7.
    发明授权
    Human protein kinase, phosphatase, and protease family members and uses thereof 失效
    新型人类蛋白激酶，磷酸酶和蛋白酶家族成员及其用途

    公开(公告)号：US07282360B2

    公开(公告)日：2007-10-16

    申请号：US11636948

    申请日：2006-12-11

    申请人： Rachel E. Meyers ,  Peter J. Olandt ,  Rosana Kapeller-Libermann ,  Rory A. J. Curtis ,  Mark Williamson ,  Nadine Weich

    发明人： Rachel E. Meyers ,  Peter J. Olandt ,  Rosana Kapeller-Libermann ,  Rory A. J. Curtis ,  Mark Williamson ,  Nadine Weich

    IPC分类号： C12N9/20 ,  C12N15/00 ,  C12N1/20 ,  C12Q1/68 ,  C07H21/04

    CPC分类号： C12N9/1205 ,  A61K38/00 ,  C07K16/40 ,  C12N9/12 ,  C12N9/16 ,  C12N9/48 ,  C12N9/6424 ,  C12N9/6427 ,  C12N9/6472 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/156

    摘要： The invention provides isolated nucleic acids molecules, designated 53070, 15985, 26583, 21953, m32404, 14089, and 23436 nucleic acid molecules, which encode novel human protein kinase family members, serine/threonine protein kinase family members, serine/threonine phosphatase family members, prolyl oligopeptidase family members, trypsin family members, trypsin serine protease family members, and ubiquitin protease family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 53070, 15985, 26583, 21953, m32404, 14089, or 23436 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 53070, 15985, 26583, 21953, m32404, 14089, or 23436 gene has been introduced or disrupted. The invention still further provides isolated 53070, 15985, 26583, 21953, m32404, 14089, or 23436 proteins, fusion proteins, antigenic peptides and anti-53070, 15985, 26583, 21953, m32404, 14089, or 23436 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供分离的核酸分子，命名为53070,15985,26583,21953，m32404,14089和23436核酸分子，其编码新的人类蛋白激酶家族成员，丝氨酸/苏氨酸蛋白激酶家族成员，丝氨酸/苏氨酸磷酸酶家族成员 ，脯氨酰寡肽酶家族成员，胰蛋白酶家族成员，胰蛋白酶丝氨酸蛋白酶家族成员和泛素蛋白酶家族成员。 本发明还提供反义核酸分子，含有53070,15985,26583,21953，m32404,14089或23436核酸分子的重组表达载体，已经引入表达载体的宿主细胞，以及非人类转基因动物，其中53070 ，15985,26583,21953，m32404,14089或23436基因已被引入或破坏。 本发明还进一步提供了分离的53070,15985,26583,21953，m32404,14089或23436蛋白，融合蛋白，抗原肽和抗-53070,15985,26583,21953，m32404,14089或23436抗体。 还提供了利用本发明组合物的诊断方法。

    2150, human protein kinase family member and uses therefor
    9.
    发明授权
    2150, human protein kinase family member and uses therefor 失效
    2150，人类蛋白激酶家族成员及其用途

    公开(公告)号：US06911317B2

    公开(公告)日：2005-06-28

    申请号：US10184563

    申请日：2002-06-27

    申请人： Rachel E. Meyers ,  Jose M. Lora

    发明人： Rachel E. Meyers ,  Jose M. Lora

    IPC分类号： C12N9/12 ,  C12Q1/48 ,  C12N1/20 ,  C12N9/20 ,  C12N15/00 ,  C12Q1/68

    CPC分类号： C12N9/12 ,  C07K2319/00 ,  C12N9/1205

    摘要： The invention provides isolated nucleic acids molecules, designated 2150 nucleic acid molecules, which encode novel protein kinase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 2150 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 2150 gene has been introduced or disrupted. The invention still further provides isolated 2150 proteins, fusion proteins, antigenic peptides and anti-2150 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新的蛋白激酶家族成员的分离的命名为2150个核酸分子的核酸分子。 本发明还提供了反义核酸分子，含有2150个核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及2150基因被引入或被破坏的非人类转基因动物。 本发明还进一步提供分离的2150蛋白，融合蛋白，抗原肽和抗-2150抗体。 还提供了利用本发明组合物的诊断和治疗方法。

    Human transferase family members and uses thereof
    10.
    发明授权
    Human transferase family members and uses thereof 失效
    人转移酶家族成员及其用途

    公开(公告)号：US07799898B2

    公开(公告)日：2010-09-21

    申请号：US11786411

    申请日：2007-04-11

    申请人： Rachel E. Meyers

    发明人： Rachel E. Meyers

    IPC分类号： C07K1/00 ,  C07K14/00 ,  C07K17/00 ,  G01N33/00

    CPC分类号： C12Q1/6883 ,  A01K2217/05 ,  A61K38/00 ,  A61K39/00 ,  C07K14/47 ,  C07K16/40 ,  C07K2319/00 ,  C12N9/1007 ,  C12N9/1025 ,  C12N9/1029 ,  C12N9/1048 ,  C12N9/1051 ,  C12N9/1096 ,  C12N9/93 ,  C12Q1/48 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Y602/01001 ,  C12Y602/01016

    摘要： The invention provides isolated nucleic acids molecules, designated 33877, 47179, 26886, 46743, 27417, 32252, and 53320 nucleic acid molecules, which encode novel human transferase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 33877, 47179, 26886, 46743, 27417, 32252, or 53320 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 33877, 47179, 26886, 46743, 27417, 32252, or 53320 gene has been introduced or disrupted. The invention still further provides isolated 33877, 47179, 26886, 46743, 27417, 32252, or 53320 proteins, fusion proteins, antigenic peptides and anti-33877, 47179, 26886, 46743, 27417, 32252, or 53320 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新的人转移酶家族成员的分离的核酸分子，命名为33877,47179,26886,4673,27417,32252和53320核酸分子。 本发明还提供反义核酸分子，含有33877,47179,26886,4673,27417,32252或53320核酸分子的重组表达载体，已经引入了表达载体的宿主细胞，以及非人类转基因动物，其中33877 ，47179,26886,46743,27417,32.252或53320基因已被引入或破坏。 本发明还进一步提供了分离的33877,47179,26886,46743,27417,32252或53320蛋白，融合蛋白，抗原肽和抗33877,47179,26886,46743,27417,32252或53320抗体。 还提供了利用本发明组合物的诊断方法。