摘要:
Disclosed is a method for screening for inhibitors of Hepatitis B Virus pX activity. The method involves contacting a test compound with (I) the pX protein of HBV, (ii) a transcription factor comprising the bZIP domain, or fragments that comprise a minimal a bZIP domain, and (iii) an oligoduplex comprising a target DNA sequence of the transcription factor to form a test mixture. After incubating the test mixture under appropriate conditions and for a sufficient time to allow pX-mediated dimerization and DNA binding of the transcription factor to occur, the level of DNA binding of the transcription factor in each test mixture is determined. A test compound is considered to be any compound that causes a decrease in the level of DNA binding in the test mixture relative to the level of DNA binding in control mixtures.
摘要:
A logical customer organization model is applied to group the individual agreements into separate logical customer organizations, wherein the groupings can be region based groupings, organization groupings and departmental groupings. Unified login identification (ID) model is applied to enable a first user to login to a portal using a first login ID to access a first asset in a first asset group according to a first logical customer organization. The unified login ID model enables the first user to use the same first login ID to access a second asset in the first asset group according to the first logical customer organization. The unified login ID model also enables the first user to login to the portal using a second login ID to access one or more assets in a second asset group according to a second logical customer organization. Each of the first and second logical customer organization may be associated with one or more asset groups and one or more user groups.
摘要:
A performance, analytics and auditing (PAA) system is configured to operate with a complex web application including a portal application and its sub systems non-intrusively. The PAA system includes a first component configured to capture behavior-related information from the portal application, a second component configured to capture performance-related information from the portal application, a third component configured to capture auditing-related information from the portal application. The PAA system is further configured to start or stop with minimal impact on the portal application, wherein the PAA system is coded using Aspect Oriented Programming (AOP) and able to collect information from multiple threads.
摘要:
At least one user is designated to manage assets including management delegations, access restrictions, and access permissions. Management responsibilities are applied based on business rules and based on a hierarchical model. The hierarchical model enables a well-defined logical flow of delegations and restrictions with pruning capability. User groups, asset groups, asset trees and asset permissions may be defined. The designated user can manage a single asset or all assets or a subset of assets. An asset may belong to one or more asset groups.
摘要:
The invention relates to newly discovered nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided.
摘要:
The invention relates to newly discovered nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided.
摘要:
A logical customer organization model is applied to group the individual agreements into separate logical customer organizations, wherein the groupings can be region based groupings, organization groupings and departmental groupings. Unified login identification (ID) model is applied to enable a first user to login to a portal using a first login ID to access a first asset in a first asset group according to a first logical customer organization. The unified login ID model enables the first user to use the same first login ID to access a second asset in the first asset group according to the first logical customer organization. The unified login ID model also enables the first user to login to the portal using a second login ID to access one or more assets in a second asset group according to a second logical customer organization. Each of the first and second logical customer organization may be associated with one or more asset groups and one or more user groups.
摘要:
The invention relates to newly discovered nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided.
摘要:
The invention relates to newly discovered nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided.
摘要:
At least one user is designated to manage assets including management delegations, access restrictions, and access permissions. Management responsibilities are applied based on business rules and based on a hierarchical model. The hierarchical model enables a well-defined logical flow of delegations and restrictions with pruning capability. User groups, asset groups, asset trees and asset permissions may be defined. The designated user can manage a single asset or all assets or a subset of assets. An asset may belong to one or more asset groups.