公开(公告)号：US09801632B2

公开(公告)日：2017-10-31

申请号：US13079848

申请日：2011-04-05

申请人： Jack Goodman ,  Gregory Hake ,  Thomas Schoon

发明人： Jack Goodman ,  Gregory Hake ,  Thomas Schoon

IPC分类号： B65B51/06 ,  A61B17/08 ,  A61B17/10 ,  B65H37/00

CPC分类号： A61B17/085 ,  A61B17/10 ,  B65H37/007 ,  Y10T156/1348

摘要： A dispensing device configured to operate with an adhesive backed mesh and backing film for tissue bonding is disclosed. The dispensing device provides for low-friction, low force pay-out of a desired length of an adhesive backed mesh to a wound site. The device prevents or eliminates distortion of the mesh prior to application to the wound site, and includes means for reducing or eliminating binding during use. The dispensing device is configured to operate in a “forward” mode (substrate to which mesh is applied passes beneath applicator after mesh is applied) to provide essentially an unobstructed view of the wound site during use.

公开(公告)号：US08118508B2

公开(公告)日：2012-02-21

申请号：US11565022

申请日：2006-11-30

申请人： Jack Goodman ,  Gregory Hake ,  Thomas Schoon ,  Thomas A. Shepard

发明人： Jack Goodman ,  Gregory Hake ,  Thomas Schoon ,  Thomas A. Shepard

IPC分类号： B43K5/14

CPC分类号： B43M11/06 ,  A61B17/00491 ,  A61M35/00

摘要： An applicator device for dispensing a polymerizable adhesive material comprising a body portion comprising a closed proximal end and an open distal end providing a cavity sized to accept a frangible container having a polymerizable adhesive material; at least one breaking member at least partially deflectable into the cavity; an annular housing movable with respect to the body portion; and a reservoir secured to the open distal end of the body portion, the reservoir further comprising an applicator; wherein the annular housing is movable relative to the body portion from a first position to a second position to deflect at least a portion of the breaking member into the cavity.

摘要翻译： 一种用于分配可聚合粘合剂材料的施加器装置，其包括主体部分，该主体部分包括封闭的近端和敞开的远端，其提供尺寸适于接受具有可聚合粘合剂材料的易碎容器的腔体; 至少部分可偏转到所述腔中的至少一个破坏构件; 可相对于主体部分移动的环形壳体; 以及储存器，其固定到所述主体部分的敞开的远端，所述储存器还包括施加器; 其中所述环形壳体可相对于所述主体部分从第一位置移动到第二位置，以将所述断裂构件的至少一部分偏转到所述空腔中。

公开(公告)号：US20110180215A1

公开(公告)日：2011-07-28

申请号：US13079848

申请日：2011-04-05

申请人： Jack Goodman ,  Gregory Hake ,  Thomas Schoon

发明人： Jack Goodman ,  Gregory Hake ,  Thomas Schoon

IPC分类号： B65B51/06

CPC分类号： A61B17/085 ,  A61B17/10 ,  B65H37/007 ,  Y10T156/1348

摘要： A dispensing device configured to operate with an adhesive backed mesh and backing film for tissue bonding is disclosed. The dispensing device provides for low-friction, low force pay-out of a desired length of an adhesive backed mesh to a wound site. The device prevents or eliminates distortion of the mesh prior to application to the wound site, and includes means for reducing or eliminating binding during use. The dispensing device is configured to operate in a “forward” mode (substrate to which mesh is applied passes beneath applicator after mesh is applied) to provide essentially an unobstructed view of the wound site during use.

摘要翻译： 公开了一种配置为用于组织粘合的粘性背衬网和背衬膜操作的分配装置。 分配装置提供了将所需长度的粘合剂背衬的网状物的低摩擦力，低力量输出到伤口部位。 该装置在施加到伤口部位之前防止或消除网状物的变形，并且包括在使用期间减少或消除结合的装置。 分配装置被配置为以“向前”模式操作（在施加网格之后通过网眼施加的基底）在使用期间基本上提供伤口部位的无障碍视图。

公开(公告)号：US07722632B2

公开(公告)日：2010-05-25

申请号：US10435236

申请日：2003-05-09

申请人： Paul T. Rothstein ,  Paul Pignato ,  Thomas Daigle ,  Jack Goodman

发明人： Paul T. Rothstein ,  Paul Pignato ,  Thomas Daigle ,  Jack Goodman

IPC分类号： A61B17/04

CPC分类号： A61B17/06061 ,  A61B17/0483 ,  A61B90/50 ,  A61B2017/0237

摘要： A device for holding a surgical suture including a base, a guide body, a cam body, a bearing member, and a spring member. The base has a top side, a front edge, and a back edge. The guide body projects from the top side of the base and defines a guide face having an entrance side and an exit side. The entrance side is adjacent the front edge and the exit side is adjacent the back edge. The cam body is pivotally mounted to the top side and forms a toothed surface positioned to selectively secure a surgical suture against the guide face. The spring member is positioned between the cam body and the bearing member, biasing the toothed surface toward the guide face.

摘要翻译： 一种用于保持包括基部，引导体，凸轮体，支承构件和弹簧构件的手术缝合线的装置。 底座具有顶侧，前边缘和后边缘。 引导体从基部的顶侧突出并且限定具有入口侧和出口侧的引导面。 入口侧邻近前缘，出口侧邻近后缘。 凸轮主体枢转地安装到顶侧并形成齿形表面，其被定位成选择性地将外科缝合线固定抵靠引导面。 弹簧构件定位在凸轮本体和轴承构件之间，将齿形表面朝向引导面偏置。

公开(公告)号：US20080243082A1

公开(公告)日：2008-10-02

申请号：US11731855

申请日：2007-03-30

申请人： Jack Goodman

发明人： Jack Goodman

IPC分类号： A61M27/00

CPC分类号： A61M25/02 ,  A61M2025/0266 ,  A61M2025/0273 ,  A61M2025/028

摘要： Devices, systems and methods for fixation of medical articles which remain in a patient's body for a period of time are provided. The articles may be secured to the patient's skin by use of a device having an arcuate channel for holding the medical article. In one device, a base member including an arcuate channel receives the medical article, which base member has a plurality of protrusions which rest against the skin providing a gap for application of a polymerizable adhesive composition which polymerizes, forming a seal around the medical article and securing the medical article to the body. Alternatively, a device including a base member having an arcuate channel is provided adhered to a flexible member. The device receives the medical article and is positioned proximate to the patient's skin. Polymerizable adhesive composition is applied to the flexible member, securing the medical article to the patient's body upon polymerization.

摘要翻译： 提供了用于固定保留在患者体内一段时间的医疗用品的装置，系统和方法。 可以通过使用具有用于保持医疗用品的弧形通道的装置将物品固定到患者的皮肤上。 在一个装置中，包括弓形通道的基部构件接收医疗用品，该基底构件具有多个突出部，该突起部靠在皮肤上，提供用于施加可聚合的粘合剂组合物的间隙，聚合性粘合剂组合物聚合，在医疗制品周围形成密封， 将医疗用品固定在身上。 或者，包括具有弓形通道的基部构件的装置被附着到柔性构件。 该装置接收医疗用品并且被定位成靠近患者的皮肤。 可聚合的粘合剂组合物施加到柔性构件上，在聚合时将医疗制品固定到患者身上。

公开(公告)号：US20080194426A1

公开(公告)日：2008-08-14

申请号：US12068150

申请日：2008-02-04

申请人： Jack Goodman ,  Matthew Torres ,  Hongjun Yang ,  David G. Mateer ,  Ian Stuart Richard Smith

发明人： Jack Goodman ,  Matthew Torres ,  Hongjun Yang ,  David G. Mateer ,  Ian Stuart Richard Smith

IPC分类号： C40B60/12

CPC分类号： G01N21/253 ,  B01L3/5027 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502746 ,  B01L7/00 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0877 ,  B01L2300/18 ,  B01L2300/1822 ,  B01L2300/1838 ,  B01L2400/0478 ,  B01L2400/0481 ,  B01L2400/0487 ,  B01L2400/06 ,  B01L2400/0622 ,  G01N21/05 ,  G01N2021/0346 ,  G01N2035/00158

摘要： A system for performing hybridization assays comprises a cartridge for housing a flow through device, where the cartridge includes a test fluid chamber for facilitating a substantially uniform flow of a test fluid mixture through the flow through device, and a fluidics station to deliver the test fluid mixture to the cartridge. The cartridge has a chip holder that holds the flow-through device, which has an array of microchannel passages. The chip holder has a support for placement of the flow though device, the test fluid chamber for directing a substantially uniform flow of a test fluid mixture through the array of microchannel passages of the flow through device, and a first port that receives the test fluid mixture. The cartridge has a sealing system for preventing the leakage of the test fluid around the flow through device. The test fluid chamber is defined in part by a spade-like surface having an inlet for the test fluid mixture.

摘要翻译： 用于进行杂交测定的系统包括用于容纳流过装置的筒，其中所述筒包括用于促进测试流体混合物通过流动装置的基本均匀流动的测试流体室，以及用于输送测试流体的流体站 混合到墨盒。 盒具有保持流通装置的芯片保持器，该流通装置具有一组微通道通道。 芯片保持器具有用于放置流通装置的支撑件，测试流体室用于引导测试流体混合物的基本上均匀的流动通过流过装置的微通道通道的阵列，以及接收测试流体的第一端口 混合物。 盒具有用于防止测试流体围绕流过装置的泄漏的密封系统。 测试流体室部分地由具有用于测试流体混合物的入口的铲形表面限定。

公开(公告)号：US20080108878A1

公开(公告)日：2008-05-08

申请号：US12004937

申请日：2007-12-21

申请人： Jack Goodman ,  Tom Daigle ,  Douglas Gubbin ,  David Kim

发明人： Jack Goodman ,  Tom Daigle ,  Douglas Gubbin ,  David Kim

IPC分类号： A61B1/32

CPC分类号： A61B17/02 ,  A61B2017/00314 ,  A61B2017/2905 ,  A61B2017/306

摘要： An improved tissue engagement device such as a suction stabilizer or retractor. The stabilizer or retractor is provided with one or more suction pods mounted to the distal end of a flexible arm. The flexible arm is coupled to a base assembly, which attaches the arm to an associated retractor or other structure that is fixedly located relative to the operative site. The base assembly includes a fixed portion, which is coupled to the retractor or other fixed mounting point and a rotatable turret, allowing rotation of the arm relative to the fixed portion of the base assembly. A tensioning mechanism mounted to the turret applies tension to compress the turret around a corresponding pivot mounted to the fixed portion of the base to rotationally lock the turret and to lock the arm in its current configuration. If the device is a suction stabilizer, it may carry a spreading/tightening mechanism along with two suction pods and the tensioning mechanism may lock the relative location of the spreading/tightening mechanism relative to the arm and operate to spread the suction pods apart from one another to provide for additional stabilization at the desired anastomosis site. If the device is a suction retractor, the tensioning mechanism may lock a pivotably mounted carrier for a single enlarged suction pod so that the suction pod is held in its desired orientation relative to the arm.

摘要翻译： 改进的组织接合装置，例如吸力稳定器或牵开器。 稳定器或牵开器设置有一个或多个安装到柔性臂的远端的抽吸舱。 柔性臂联接到基部组件，其将臂附接到相对于牵开器或相对于手术部位固定定位的其他结构。 基座组件包括固定部分，该固定部分联接到牵开器或其他固定安装点以及可转动的转台，允许臂相对于基座组件的固定部分旋转。 安装到转台上的张紧机构施加张力以围绕安装到基座的固定部分的相应枢轴压缩转台，以旋转地锁定转台并将臂锁定在其当前配置中。 如果设备是吸力稳定器，则它可以与两个吸力舱一起携带扩张/紧固机构，并且张紧机构可以相对于手臂锁定扩张/紧固机构的相对位置，并且操作以将抽吸荚与一个 另一个在所需的吻合部位提供额外的稳定。 如果装置是抽吸牵开器，则张紧机构可以锁定可枢转地安装的载体以用于单个扩大的吸入舱，使得吸入舱相对于臂保持在其期望的方向。

公开(公告)号：US07326561B2

公开(公告)日：2008-02-05

申请号：US09926094

申请日：2000-12-20

申请人： Jack Goodman ,  Matthew Torres ,  Hongjun Yang ,  David G. Mateer ,  Ian Stuart Richard Smith

发明人： Jack Goodman ,  Matthew Torres ,  Hongjun Yang ,  David G. Mateer ,  Ian Stuart Richard Smith

IPC分类号： C12M1/36

CPC分类号： G01N21/253 ,  B01L3/5027 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502746 ,  B01L7/00 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0877 ,  B01L2300/18 ,  B01L2300/1822 ,  B01L2300/1838 ,  B01L2400/0478 ,  B01L2400/0481 ,  B01L2400/0487 ,  B01L2400/06 ,  B01L2400/0622 ,  G01N21/05 ,  G01N2021/0346 ,  G01N2035/00158

摘要： A system for performing hybridization assays comprises a cartridge for housing a flow through device, where the cartridge includes a test fluid chamber for facilitating a substantially uniform flow of a test fluid mixture through the flow through device, and a fluidics station to deliver the test fluid mixture to the cartridge. The cartridge has a chip holder that holds the flow-through device, which has an array of microchannel passages. The chip holder has a support for placement of the flow though device, the test fluid chamber for directing a substantially uniform flow of a test fluid mixture through the array of microchannel passages of the flow through device, and a first port that receives the test fluid mixture. The cartridge has a sealing system for preventing the leakage of the test fluid around the flow through device. The test fluid chamber is defined in part by a spade-like surface having an inlet for the test fluid mixture.

摘要翻译： 用于进行杂交测定的系统包括用于容纳流过装置的筒，其中所述筒包括用于促进测试流体混合物通过流动装置的基本均匀流动的测试流体室，以及用于输送测试流体的流体站 混合到墨盒。 盒具有保持流通装置的芯片保持器，该流通装置具有阵列的微通道通道。 芯片保持器具有用于放置流通装置的支撑件，测试流体室用于引导测试流体混合物的基本上均匀的流动通过流过装置的微通道通道的阵列，以及接收测试流体的第一端口 混合物。 盒具有用于防止测试流体围绕流过装置的泄漏的密封系统。 测试流体室部分地由具有用于测试流体混合物的入口的铲形表面限定。

公开(公告)号：US07311664B2

公开(公告)日：2007-12-25

申请号：US11003100

申请日：2004-12-03

申请人： Jack Goodman ,  Tom Daigle ,  Douglas H. Gubbin ,  David J. S. Kim

发明人： Jack Goodman ,  Tom Daigle ,  Douglas H. Gubbin ,  David J. S. Kim

IPC分类号： A61B1/32

CPC分类号： A61B17/02 ,  A61B2017/00314 ,  A61B2017/2905 ,  A61B2017/306

摘要： An improved tissue engagement device such as a suction stabilizer or retractor. The stabilizer or retractor is provided with one or more suction pods mounted to the distal end of a flexible arm. The flexible arm is coupled to a base assembly, which attaches the arm to an associated retractor or other structure that is fixedly located relative to the operative site. The base assembly includes a fixed portion, which is coupled to the retractor or other fixed mounting point and a rotatable turret, allowing rotation of the arm relative to the fixed portion of the base assembly. A tensioning mechanism mounted to the turret applies tension to compress the turret around a corresponding pivot mounted to the fixed portion of the base to rotationally lock the turret and to lock the arm in its current configuration. If the device is a suction stabilizer, it may carry a spreading/tightening mechanism along with two suction pods and the tensioning mechanism may lock the relative location of the spreading/tightening mechanism relative to the arm and operate to spread the suction pods apart from one another to provide for additional stabilization at the desired anastomosis site. If the device is a suction retractor, the tensioning mechanism may lock a pivotably mounted carrier for a single enlarged suction pod so that the suction pod is held in its desired orientation relative to the arm.

摘要翻译： 改进的组织接合装置，例如吸力稳定器或牵开器。 稳定器或牵开器设置有一个或多个安装到柔性臂的远端的抽吸舱。 柔性臂联接到基部组件，其将臂附接到相对于牵开器或相对于手术部位固定定位的其他结构。 基座组件包括固定部分，该固定部分联接到牵开器或其他固定安装点以及可转动的转台，允许臂相对于基座组件的固定部分旋转。 安装到转台上的张紧机构施加张力以围绕安装到基座的固定部分的相应枢轴压缩转台，以旋转地锁定转台并将臂锁定在其当前配置中。 如果设备是吸力稳定器，则它可以与两个吸力舱一起携带扩张/紧固机构，并且张紧机构可以相对于手臂锁定扩张/紧固机构的相对位置，并且操作以将抽吸荚与一个 另一个在所需的吻合部位提供额外的稳定。 如果装置是抽吸牵开器，则张紧机构可以锁定可枢转地安装的载体以用于单个扩大的吸入舱，使得吸入舱相对于臂保持在其期望的方向。

公开(公告)号：US20050164410A1

公开(公告)日：2005-07-28

申请号：US10912574

申请日：2004-08-06

申请人： John Leland ,  Haresh Shah ,  John Kenten ,  Jack Goodman ,  George Lowke ,  Yuzaburo Namba ,  Gary Blackburn ,  Richard Massey

发明人： John Leland ,  Haresh Shah ,  John Kenten ,  Jack Goodman ,  George Lowke ,  Yuzaburo Namba ,  Gary Blackburn ,  Richard Massey

IPC分类号： C07H21/00 ,  C12Q1/68 ,  G01N1/40 ,  G01N21/66 ,  G01N21/76 ,  G01N33/543 ,  G01N33/58

CPC分类号： G01N33/582 ,  C07H21/00 ,  G01N1/40 ,  G01N21/66 ,  G01N21/76 ,  G01N33/54313 ,  G01N33/54326 ,  G01N33/54366 ,  G01N33/5438

摘要： An apparatus for performing a binding assay for an analyte of interest present in a sample based upon measurement of electrochemiluminescence at an electrode surface comprising a cell defining a sample containing volume intersecting with inlet and outlet means, an electrode having a substantially horizontally positioned surface exposed to and positioned below a portion of the sample containing volume, means for impressing electrochemical energy upon said electrode sufficient to generate luminescence, means for magnetically collecting particles along said surface and means for measuring the luminescence generated at said electrode.

摘要翻译： 基于在包括限定与入口和出口装置相交的体积的样品的细胞的电极表面上测量电化学发光，对样品中存在的感兴趣分析物进行结合测定的装置，具有暴露于 并且位于所述样品容纳体积的一部分下方，用于在所述电极上施加足以产生发光的电化学能量的装置，用于沿着所述表面磁性收集颗粒的装置和用于测量在所述电极处产生的发光的装置。