Step-scan ion trap mass spectrometry for high speed proteomics
    2.
    发明授权
    Step-scan ion trap mass spectrometry for high speed proteomics 有权
    步进扫描离子阱质谱法用于高速蛋白质组学

    公开(公告)号:US08507846B2

    公开(公告)日:2013-08-13

    申请号:US13566352

    申请日:2012-08-03

    IPC分类号: B01D59/44 H01J49/00

    摘要: An ion trap mass spectrometer and methods for obtaining a mass spectrum of ions by step scanning the driving frequency in frequency increments over a bandwidth, wherein for each step a specific frequency is held for a fixed number of complete cycles, wherein each specific frequency is changed continuously to the frequency in the next step, and wherein each specific frequency in each step starts at phase zero position.

    摘要翻译: 一种离子阱质谱仪和用于通过在带宽上以频率增量扫描驱动频率来获得离子质谱的方法,其中对于每个步骤,特定频率保持固定数量的完整循环,其中每个特定频率被改变 在下一步骤中连续地进入频率,并且其中每个步骤中的每个特定频率从相位零位置开始。

    STEP-SCAN ION TRAP MASS SPECTROMETRY FOR HIGH SPEED PROTEOMICS
    3.
    发明申请
    STEP-SCAN ION TRAP MASS SPECTROMETRY FOR HIGH SPEED PROTEOMICS 有权
    用于高速度保护的步进扫描质谱分析

    公开(公告)号:US20130032709A1

    公开(公告)日:2013-02-07

    申请号:US13566352

    申请日:2012-08-03

    IPC分类号: H01J49/34 H01J49/36 H01J49/26

    摘要: An ion trap mass spectrometer and methods for obtaining a mass spectrum of ions by step scanning the driving frequency in frequency increments over a bandwidth, wherein for each step a specific frequency is held for a fixed number of complete cycles, wherein each specific frequency is changed continuously to the frequency in the next step, and wherein each specific frequency in each step starts at phase zero position.

    摘要翻译: 一种离子阱质谱仪和用于通过在带宽上以频率增量扫描驱动频率来获得离子质谱的方法,其中对于每个步骤,特定频率保持固定数量的完整循环,其中每个特定频率被改变 在下一步骤中连续地进入频率,并且其中每个步骤中的每个特定频率从相位零位置开始。

    MASS SPECTROMETER AND METHODS FOR DETECTING LARGE BIOMOLECULES
    5.
    发明申请
    MASS SPECTROMETER AND METHODS FOR DETECTING LARGE BIOMOLECULES 有权
    用于检测大生物分子的质谱仪和方法

    公开(公告)号:US20110284733A1

    公开(公告)日:2011-11-24

    申请号:US12785945

    申请日:2010-05-24

    IPC分类号: H01J49/26 B01D59/44

    CPC分类号: H01J49/025 H01J49/0027

    摘要: A mass spectrometer and methods for obtaining the mass spectrum of a single macromolecular or biomolecular ion in a mass spectrometer. The methods include creating single macromolecular or biomolecular primary ions in an ion trap by ionization of a macromolecule or biomolecule; ejecting half of the primary ions for detection with a first charge detector; ejecting half of the primary ions to impact upon a conversion dynode, thereby creating secondary ions for detection with charge amplification detector such as a channeltron or an electromultiplier or an MCP.

    摘要翻译: 质谱仪和在质谱仪中获得单个大分子或生物分子离子的质谱的方法。 该方法包括通过大分子或生物分子的离子化在离子阱中产生单个大分子或生物分子一级离子; 用第一电荷检测器喷射一半的初级离子用于检测; 喷射一半的初级离子以冲击转换倍增极,从而产生二次离子,以便用电荷放大检测器(例如通道电极或电倍增管或MCP)进行检测。

    APPARATUSES AND METHODS FOR PORTABLE MASS SPECTROMETRY
    6.
    发明申请
    APPARATUSES AND METHODS FOR PORTABLE MASS SPECTROMETRY 有权
    便携式质谱仪的装置和方法

    公开(公告)号:US20110147581A1

    公开(公告)日:2011-06-23

    申请号:US12976543

    申请日:2010-12-22

    IPC分类号: H01J49/26

    摘要: Methods and apparatuses for portable mass spectrometry are disclosed. The apparatuses comprise at least one source of ionized analyte, at least one frequency scanning subsystem, at least one detector, and optionally at least one vacuum pump, and are portable. In some embodiments, the apparatuses comprise multiple sources of ionized analyte and/or are configured to obtain mass spectra of a large analyte, such as analyte with an m/z ratio of at least 105, or analyte with a molecular weight of at least 105 Da, as well as mass spectra of small molecule analyte. In some embodiments, the methods comprise obtaining mass spectra with a portable apparatus described above.

    摘要翻译: 公开了便携式质谱法的方法和装置。 该装置包括至少一个离子化分析物源,至少一个频率扫描子系统,至少一个检测器和可选的至少一个真空泵,并且是便携式的。 在一些实施方案中,装置包括多个电离分析物源和/或配置成获得大分析物的质谱,例如m / z比至少为105的分析物,或分子量至少为105的分析物 Da,以及小分子分析物的质谱。 在一些实施例中,所述方法包括使用上述便携式装置获得质谱。

    Mass spectrometer and methods for detecting large biomolecules
    8.
    发明授权
    Mass spectrometer and methods for detecting large biomolecules 有权
    质谱仪和检测大生物分子的方法

    公开(公告)号:US08258464B2

    公开(公告)日:2012-09-04

    申请号:US12785945

    申请日:2010-05-24

    IPC分类号: H01J49/34 H01J37/244

    CPC分类号: H01J49/025 H01J49/0027

    摘要: A mass spectrometer and methods for obtaining the mass spectrum of a single macromolecular or biomolecular ion in a mass spectrometer. The methods include creating single macromolecular or biomolecular primary ions in an ion trap by ionization of a macromolecule or biomolecule; ejecting half of the primary ions for detection with a first charge detector; ejecting half of the primary ions to impact upon a conversion dynode, thereby creating secondary ions for detection with charge amplification detector such as a channeltron or an electromultiplier or an MCP.

    摘要翻译: 质谱仪和在质谱仪中获得单个大分子或生物分子离子的质谱的方法。 该方法包括通过大分子或生物分子的离子化在离子阱中产生单个大分子或生物分子一级离子; 用第一电荷检测器喷射一半的初级离子用于检测; 喷射一半的初级离子以冲击转换倍增极,从而产生二次离子,以便用电荷放大检测器(例如通道电极或电倍增管或MCP)进行检测。

    Cooling system for an electronic rack
    9.
    发明授权
    Cooling system for an electronic rack 有权
    电子机架的冷却系统

    公开(公告)号:US08879268B2

    公开(公告)日:2014-11-04

    申请号:US13371497

    申请日:2012-02-13

    IPC分类号: H05K7/20

    摘要: The present invention discloses a cooling system for an electronic rack, comprising: an electronic rack comprising at least one side wall; at least one electronic chassis comprising a top wall and at least one side wall and disposed inside the electronic rack for housing at least one modular electronics equipment comprising a plurality of electronic components and at least one stationary thermal interface arranged above the plurality of electronic components; a first detachable thermal interface arranged between the top wall of the at least one electronic chassis and the at least one modular electronic equipment; and at least one second detachable thermal interface arranged between the at least one side wall of the electronic rack and the at least one side wall of the at least one electronic chassis.

    摘要翻译: 本发明公开了一种电子机架的冷却系统,包括:电子机架,包括至少一个侧壁; 至少一个电子底盘,其包括顶壁和至少一个侧壁并且设置在所述电子机架内部,用于容纳包括多个电子部件和布置在所述多个电子部件上方的至少一个固定热接口的至少一个模块化电子设备; 布置在所述至少一个电子底盘的顶壁和所述至少一个模块化电子设备之间的第一可拆卸热接口; 以及布置在所述电子机架的所述至少一个侧壁与所述至少一个电子底盘的所述至少一个侧壁之间的至少一个第二可拆卸热接口。

    OPTICAL PATH SWITCHING DEVICE
    10.
    发明申请
    OPTICAL PATH SWITCHING DEVICE 审中-公开
    光路切换装置

    公开(公告)号:US20120308178A1

    公开(公告)日:2012-12-06

    申请号:US13152366

    申请日:2011-06-03

    IPC分类号: G02B6/36

    CPC分类号: G02B6/38

    摘要: An optical path switching device comprises at least one movable carrier plate; at least two optical fiber connection sockets arranged on the movable carrier plate and each connected with an optical fiber; and a driving device mechanical coupled to the movable carrier plate, driving the movable carrier plate to carry one of the optical fiber connection sockets to a position corresponding to an optical fiber connection plug, whereby the optical fiber connection plug can be coupled to the optical fiber connection socket connecting with an intended optical path. The present invention switches the optical path in a purely-mechanical way without using any optical component. The present invention has advantages of simple structure, low cost and low signal loss.

    摘要翻译: 光路切换装置包括至少一个可动载板; 至少两个光纤连接插座,布置在可移动的载板上并且每个与光纤相连; 以及驱动装置,其机械地联接到所述可移动承载板,驱动所述可移动的承载板将所述光纤连接插座中的一个承载到与光纤连接插头相对应的位置,由此所述光纤连接插头可以耦合到所述光纤 连接插座与预期的光路连接。 本发明以纯机械方式切换光路而不使用任何光学部件。 本发明结构简单,成本低,信号损耗低。