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    Mutant proteins and methods for selecting them
    2.
    发明授权
    Mutant proteins and methods for selecting them 有权
    突变蛋白和选择它们的方法

    公开(公告)号：US09081020B2

    公开(公告)日：2015-07-14

    申请号：US12866594

    申请日：2009-02-05

    申请人： Malcolm Peter Weir ,  Richard Henderson ,  Christopher Gordon Tate ,  Edward Christopher Hulme

    发明人： Malcolm Peter Weir ,  Richard Henderson ,  Christopher Gordon Tate ,  Edward Christopher Hulme

    IPC分类号： G01N33/74 ,  G01N33/68 ,  G01N33/53 ,  C07K14/705

    CPC分类号： G01N33/74 ,  C07K14/70571 ,  G01N33/6872 ,  G01N2333/726

    摘要： A method for selecting a membrane protein with increased stability, the method comprising: a) providing one or more mutants of a parent membrane protein in a membrane-containing composition, wherein the one or more mutants are exposed to an amount of a membrane destabilizing agent which is effective to destabilize the parent membrane protein in-situ, b) determining whether the or each mutant membrane protein has increased stability with respect to its structure and/or a biological activity compared to the stability of the parent membrane protein with respect to its structure and/or the same biological activity, and c) selecting the one or more mutants which have increased stability compared to the stability of the parent membrane protein.

    摘要翻译： 一种用于选择具有增加的稳定性的膜蛋白的方法，所述方法包括：a）在含膜组合物中提供一种或多种亲本膜蛋白的突变体，其中所述一种或多种突变体暴露于一定量的膜去稳定剂 其有效地原位破坏亲本膜蛋白质，b）与相对于其亲本膜蛋白的稳定性相比，确定该突变膜蛋白或每个突变膜蛋白是否相对于其结构和/或生物活性具有增加的稳定性 结构和/或相同的生物活性，以及​​c）选择与亲本膜蛋白的稳定性相比具有增加的稳定性的一种或多种突变体。

    APPLIANCE CONFIGURED TO CIRCULATE AIR DURING A WASH CYCLE
    3.
    发明申请
    APPLIANCE CONFIGURED TO CIRCULATE AIR DURING A WASH CYCLE 审中-公开
    设备配置在循环中循环空气

    公开(公告)号：US20120298142A1

    公开(公告)日：2012-11-29

    申请号：US13116592

    申请日：2011-05-26

    申请人： Brent Alden Junge ,  David Beers ,  Nicholas Okruch, JR. ,  Richard Henderson ,  Ranjeet Patil

    发明人： Brent Alden Junge ,  David Beers ,  Nicholas Okruch, JR. ,  Richard Henderson ,  Ranjeet Patil

    IPC分类号： A47L15/42 ,  F28D15/02

    CPC分类号： A47L15/4257 ,  A47L15/483 ,  A47L15/488 ,  A47L2401/18 ,  A47L2401/19 ,  A47L2501/11 ,  A47L2501/12 ,  F28D20/023

    摘要： An appliance such as a dishwasher is configured to re-circulate air to reduce the amount of air with high moisture content that is expelled from the dishwasher. In one embodiment, the dishwasher comprises a wash zone in which objects are positioned to be washed and a door assembly, secured to the dishwasher in sealing engagement. Air from an upper region of the wash zone is drawn into a door cavity in the door assembly and re-circulated to a lower region of the wash zone. Inside of the door cavity is a thermal sink with a surface on which vapor in the air condenses, thereby lowering the relative humidity of the air that is ejected from the door assembly and into the lower region of the wash zone.

    摘要翻译： 诸如洗碗机的装置被配置为重新循环空气以减少从洗碗机排出的高含水量的空气量。 在一个实施例中，洗碗机包括洗涤区域，物体被定位成被清洗，门组件以与密封接合的方式固定在洗碗机上。 来自洗涤区域的上部区域的空气被吸入门组件中的门腔中并且再循环到洗涤区域的下部区域。 门腔内部是具有表面的散热器，空气中的蒸气冷凝，从而降低从门组件喷射到洗涤区域的下部区域中的空气的相对湿度。

    Material submergence system
    4.
    发明申请
    Material submergence system 有权
    物料淹没系统

    公开(公告)号：US20080206473A1

    公开(公告)日：2008-08-28

    申请号：US11998943

    申请日：2007-12-03

    申请人： Chris T. Vild ,  Richard Henderson ,  Richard C. Chandler

    发明人： Chris T. Vild ,  Richard Henderson ,  Richard C. Chandler

    IPC分类号： B05D1/18

    CPC分类号： C25C3/04 ,  C22B9/05 ,  C22B9/055 ,  C22B21/0084 ,  C22B21/064 ,  C25C7/06

    摘要： A molten metal submergence device includes a submergence chamber, an inlet pipe, and a vortex breaker. The submergence chamber is defined by a side wall and includes an inlet in communication with an associated molten metal bath and an outlet in communication with the associated molten metal bath. The inlet is positioned in relation to the side wall such that material passing through the inlet is introduced at least substantially tangentially to the side wall. The inlet pipe is in communication with the inlet of the submergence chamber. The inlet pipe is configured to depend from a wall of the submergence chamber within the confines of the side wall. The vortex breaker is disposed in the submergence chamber between the inlet and the outlet.

    摘要翻译： 熔融金属浸没装置包括浸没室，入口管和涡流破坏器。 浸没室由侧壁限定，并且包括与相关联的熔融金属浴连通的入口和与相关联的熔融金属浴连通的出口。 入口相对于侧壁定位，使得通过入口的材料至少基本上相对于侧壁被引入。 入口管与浸没室的入口连通。 入口管被构造成从侧壁的范围内的淹没室的壁上。 涡流破碎器设置在入口和出口之间的浸没室中。

    High resolution fan control at high PWM frequency with a low clock frequency input
    5.
    发明授权
    High resolution fan control at high PWM frequency with a low clock frequency input 有权
    高分辨率风扇控制在高PWM频率，低时钟频率输入

    公开(公告)号：US06765422B1

    公开(公告)日：2004-07-20

    申请号：US10456876

    申请日：2003-06-05

    申请人： Mehmet Aslan ,  Richard Henderson ,  Chungwai Benedict Ng

    发明人： Mehmet Aslan ,  Richard Henderson ,  Chungwai Benedict Ng

    IPC分类号： H03K317

    CPC分类号： H03K7/08 ,  H02P7/29

    摘要： The present invention enables an IC to have a fast PWM while maintaining the low frequency clock requirement of the temperature measurement. Methods are presented to increase the resolution of the control using a relatively low input clock. According to one method, the numerator and denominator of the PWM duty cycle equation are adjusted to achieve a desired resolution. According to another method, a determined number of PWM cycles are used to set the PWM duty cycle. For example, an averaging of 1024 duty cycles may be used to achieve an increased resolution of the duty cycle as compared to using only one duty cycle. According to yet another method, an error integrating loop is used to determine the level of the next cycle. The number of cycles used to reach the target PWM duty cycle depends on the desired resolution.

    摘要翻译： 本发明使IC能够在保持温度测量的低频时钟要求的同时具有快速PWM。 提出了使用较低输入时钟来提高控制分辨率的方法。 根据一种方法，调整PWM占空比方程的分子和分母以达到期望的分辨率。 根据另一种方法，使用确定数量的PWM周期来设置PWM占空比。 例如，与仅使用一个占空比相比，可以使用1024个占空比的平均值来实现增加的占空比分辨率。 根据另一种方法，使用误差积分环来确定下一周期的水平。 用于达到目标PWM占空比的周期数取决于所需的分辨率。

    Adjustable king pin assembly
    6.
    发明授权
    Adjustable king pin assembly 失效
    可调节主销总成

    公开(公告)号：US4923204A

    公开(公告)日：1990-05-08

    申请号：US258707

    申请日：1988-10-17

    申请人： Richard Henderson

    发明人： Richard Henderson

    IPC分类号： B62D53/08

    CPC分类号： B62D53/0842

    摘要： An adjustable king pin assembly for releasably mating with a fifth wheel assembly on a tractor-trailer arrangement. The king pin is secured to a plate which plate is slidably positioned for longitudinal movement with respect to the frame of the trailer in a space between spaced, elongated, longitudinally aligned guide bars. Spaced longitudinally aligned apertures are provided in the plate or guide bars, and an appropriate locking mechanism, secured to the assembly, is releasably movable into locking position in any one of each one of the apertures to securely hold the plate in position against longitudinal movement. An appropriate mechanical control mechanism is provided for moving the locking means from and into locking position. The assembly according to the invention provides an economical and easy-to-operate system for longitudinally positioning the king pin.

    摘要翻译： 一种可调节的主销组件，用于与拖拉机 - 拖车装置上的第五轮组件可释放地配合。 主销固定到板上，该板被可滑动地定位成在间隔的，细长的纵向对准的导杆之间的空间中相对于拖车的框架纵向运动。 间隔的纵向对准的孔设置在板或引导杆中，并且固定到组件的适当的锁定机构可释放地移动到每个孔中的任一个中的锁定位置，以将板牢固地保持在适当位置以防止纵向运动。 提供适当的机械控制机构用于将锁定装置从锁定位置移动到锁定位置。 根据本发明的组件提供了一种经济且易于操作的系统，用于纵向定位主销。

    Noise suppressing welding helmet
    7.
    发明授权
    Noise suppressing welding helmet 失效
    噪音抑制焊接头盔

    公开(公告)号：US4103359A

    公开(公告)日：1978-08-01

    申请号：US773633

    申请日：1977-02-28

    申请人： Perry J. Rieppel ,  Harold Richard Henderson

    发明人： Perry J. Rieppel ,  Harold Richard Henderson

    IPC分类号： B23K9/32 ,  A61F9/06 ,  A61F11/14

    CPC分类号： A42B3/166 ,  A61F11/14 ,  A61F9/06

    摘要： A welder's helmet having means to reduce the level of noise reaching a welder's ears when the helmet is positioned for welding. The helmet is characterized by the fact that the sound reducing means while fixed to the helmet does not contact or rest upon the head, ears or face of the welder thus not interfering with normal atmosphere circulation between the welder's head and helmet.

    摘要翻译： 焊工的头盔具有在头盔被定位用于焊接时降低到达焊工耳朵的噪音水平的手段。 头盔的特征在于，固定在头盔上的减声装置不会接触或搁置在焊机的头部，耳朵或表面上，从而不妨碍焊工的头部和头盔之间的正常的大气环流。

    Compiler operation for handling conditional statements
    8.
    发明授权
    Compiler operation for handling conditional statements 有权
    用于处理条件语句的编译器操作

    公开(公告)号：US09134977B2

    公开(公告)日：2015-09-15

    申请号：US12714236

    申请日：2010-02-26

    申请人： Jason I. H. Baron ,  Richard Henderson ,  Roland McGrath

    发明人： Jason I. H. Baron ,  Richard Henderson ,  Roland McGrath

    IPC分类号： G06F9/45

    CPC分类号： G06F8/443

    摘要： A computer-implemented method and apparatus for optimizing conditional code by identifying conditional code in a source code, adding a no-operation instruction to an executable code corresponding to the source code in place of the conditional code, adding an entry to a table to pair the no-operation instruction to the conditional code, compiling the conditional code, and storing the compiled conditional code separate from the executable code. A computer-implemented method and apparatus to optimize conditional code by loading an executable code to be executed, checking whether conditional code associated with the executable code is enabled for execution, looking up a location of a no-operation instruction in a table and a location of a compiled conditional code in the table, and replacing the no-operation instruction in the executable code with the compiled conditional code.

    摘要翻译： 一种用于通过识别源代码中的条件代码来优化条件代码的计算机实现的方法和装置，将不操作指令添加到与源代码相对应的可执行代码以代替条件代码，将条目添加到表中 对条件代码的无操作指令，编译条件代码，以及将编译的条件代码与可执行代码分开存储。 一种通过加载要执行的可执行代码来优化条件代码的计算机实现的方法和装置，检查与可执行代码相关联的条件代码是否被执行，查找表中的无操作指令的位置和位置 的编译条件代码，并用可编译的条件代码替换可执行代码中的无操作指令。