-
公开(公告)号:US20210251067A1
公开(公告)日:2021-08-12
申请号:US17255034
申请日:2019-06-25
发明人: Dennis Pohle , Christian Schulz , Ilona Rolfes
IPC分类号: H05H1/00
摘要: A probe for measuring plasma parameters by means of active plasma resonance spectroscopy comprises an external coupling, a balun, an internal coupling, and a probe head. It is provided that the couplings, the balun, and the probe head are integrated in an electrically-insulating substrate cylinder, and the substrate cylinder has a layered structure made from multiple substrate layers along its rotational axis. In this way, a probe for measuring plasma parameters is provided which enables an improved measurement of the plasma parameters, wherein the plasma is influenced as little as possible during the measurement of the plasma parameters.
-
公开(公告)号:US08933629B2
公开(公告)日:2015-01-13
申请号:US14075026
申请日:2013-11-08
IPC分类号: H01J7/24 , H01J31/26 , H01J13/48 , H01J15/04 , H01J17/36 , H05B37/00 , H05B39/00 , H05B41/00 , H01J37/32 , H01J37/04 , B44C1/22 , C03C15/00 , C03C25/68 , C23F1/00
CPC分类号: H01J37/04 , H01J37/32009 , H01J37/32091 , H01J37/32146 , H01J37/32165 , H01J37/32706
摘要: A method of establishing a DC bias in front of at least one electrode in a plasma operating apparatus by applying an RF voltage with at least two harmonic frequency components with a controlled relative phase between the components, where at least one of the higher frequency components is established as an even multiple of the lower frequency component.
摘要翻译: 一种在等离子体操作装置中在至少一个电极前面建立直流偏压的方法,该方法是通过施加具有至少两个谐波频率分量的RF电压,该至少两个谐波频率分量与组件之间具有受控的相对相位,其中至少一个较高频率分量为 建立为低频分量的偶数倍。
-
3.
公开(公告)号:US20240207451A1
公开(公告)日:2024-06-27
申请号:US18491138
申请日:2023-10-20
申请人: SPARINGVISION , RUHR-UNIVERSITÄT BOCHUM , INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , SORBONNE UNIVERSITE
发明人: Deniz DALKARA
CPC分类号: A61K48/0058 , A61K38/1709 , A61K38/177 , C07K14/47 , C12N15/86 , C12N2750/14122 , C12N2750/14143 , C12N2750/14145
摘要: The present invention concerns a new gene therapy approach to increase light-sensitivity in degenerating cones in advanced stages of rod-cone dystrophy (RCD) mediated by G-protein-gated inwardly rectifying potassium channel (GIRK), in particular GIRK4 S143T, activated by G proteins recruited by cone opsin expressed in degenerating cones.
-
公开(公告)号:US20220277185A1
公开(公告)日:2022-09-01
申请号:US17636942
申请日:2020-08-20
发明人: Philip SCHMITT , Martin HOFFMANN
摘要: A passive micromechanical counter for counting and storing a number of mechanical pulses includes at least one memory cell, the memory cell having a cell input, a latching mechanism and an electromechanical coding unit, the cell input being designed to mechanically transmit the mechanical pulse to the latching mechanism, and the latching mechanism being designed to store the number of mechanical pulses transmitted by means of its discrete latching position. It is provided that an electrical digital signal can be generated by applying an electrical voltage to the electromechanical coding unit, the electrical digital signal representing the discrete latching position of the latching mechanism.
-
公开(公告)号:US20200306279A1
公开(公告)日:2020-10-01
申请号:US15779745
申请日:2016-11-30
申请人: Forschungszentrum Borstel Leibniz-Zentrum Für Medizin und Biowissenschaften , Universität Rostock , Ruhr-Universität Bochum
发明人: Marcus PETERS , Otto HOLST , Christian VOGEL , Alice VOSS
IPC分类号: A61K31/7028 , C07H15/04 , A61K35/744 , A61K35/745 , A61K47/64 , A61K9/00 , A61P29/00 , A61P37/08
摘要: The present invention relates to L-arabino-oligosaccharides, in particular synthetically produced L-arabino-oligosaccharides and their uses for the prophylaxis of allergic reactions in mammals.
-
公开(公告)号:US20190285651A1
公开(公告)日:2019-09-19
申请号:US16349205
申请日:2017-11-21
发明人: Klaus Gerwert , Andreas Nabers , Jonas Schartner
IPC分类号: G01N33/68 , G01N21/552
摘要: The invention provides a combined immuno-infrared assay for the differential diagnosis and sub classification of Alzheimer's disease into different disease stages. The method can be applied for assured disease diagnostics and patient stratification. The assay considers the label-free detection of the change within the Amyloid-beta peptide and Tauprotein secondary structure distribution in bodily fluids. This secondary structure change from native to β-sheet enriched isoforms appears years before clinical disease manifestation. Now, the combined method utilizes this shift for diagnostics based on liquid biopsies.
-
公开(公告)号:US11800627B2
公开(公告)日:2023-10-24
申请号:US17255034
申请日:2019-06-25
发明人: Dennis Pohle , Christian Schulz , Ilona Rolfes
CPC分类号: H05H1/0037 , H01J37/32935 , H01J37/32972
摘要: A probe for measuring plasma parameters by means of active plasma resonance spectroscopy comprises an external coupling, a balun, an internal coupling, and a probe head. It is provided that the couplings, the balun, and the probe head are integrated in an electrically-insulating substrate cylinder, and the substrate cylinder has a layered structure made from multiple substrate layers along its rotational axis. In this way, a probe for measuring plasma parameters is provided which enables an improved measurement of the plasma parameters, wherein the plasma is influenced as little as possible during the measurement of the plasma parameters.
-
8.
公开(公告)号:US20230159609A1
公开(公告)日:2023-05-25
申请号:US17995880
申请日:2020-07-10
申请人: Sorbonne Université , Centre National de la Recherche Scientifique , INSERM (Institut National de la Santé et de la Recherche Médicale) , Ruhr-Universität Bochum , Centrre Hospitalier National d'Ophtalmologie Quinze-Vingts
发明人: Deniz DALKARA , Cardillia-Joe SIMON , Stefan HERLITZE , José-Alain SAHEL , Isabelle AUDO , Serge PICAUD , Stéphane Bertin
IPC分类号: C07K14/705 , C12N15/86 , C07K14/005 , A61P27/02 , A61P25/00
CPC分类号: C07K14/705 , C12N15/86 , C07K14/005 , A61P27/02 , A61P25/00 , C12N2750/14143 , C12N2750/14145 , C12N2750/14171 , C12N2750/14122 , A61K48/00
摘要: The present invention concerns a new gene therapy approach to increase light-sensitivity in degenerating cones in advanced stages of rod-cone dystrophy (RCD) mediated by G-protein-gated-K+ channel (GIRK), in particular GIRK2, activated by G proteins recruited by cone opsin expressed in degenerating cones.
-
公开(公告)号:US20210039319A1
公开(公告)日:2021-02-11
申请号:US16491851
申请日:2018-02-13
IPC分类号: B29C64/386 , B29C64/118 , B33Y50/00
摘要: Beginning on a starting area on a surface of a digital model, a layered subdivision of the model takes place to produce a three-dimensional object. Positioning of the layers on the starting area is based on calculation of a distance field, which assigns to each point of the model volume a shortest distance within the volume to the nearest starting area. For each discrete point of a layer defined by a distance field an orientation of a processing head is determined. The surface normal of the layer is calculated or gradient vectors of the distance field are calculated, which show a direction of the steepest rise in distances for the discrete point. Shape and distribution of layers conform to the shape of the digital model. The sequence for the adaptive construction results from the assignment of the layers to distance values, beginning with a lowest distance value in ascending order.
-
公开(公告)号:US12008432B2
公开(公告)日:2024-06-11
申请号:US17636942
申请日:2020-08-20
发明人: Philip Schmitt , Martin Hoffmann
CPC分类号: G06M1/108 , B81B3/0064 , B81B2201/0292 , B81B2203/04
摘要: A passive micromechanical counter for counting and storing a number of mechanical pulses includes at least one memory cell, the memory cell having a cell input, a latching mechanism and an electromechanical coding unit, the cell input being designed to mechanically transmit the mechanical pulse to the latching mechanism, and the latching mechanism being designed to store the number of mechanical pulses transmitted by means of its discrete latching position. It is provided that an electrical digital signal can be generated by applying an electrical voltage to the electromechanical coding unit, the electrical digital signal representing the discrete latching position of the latching mechanism.
-
-
-
-
-
-
-
-
-