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    DENTAL COMPOSITION
    2.
    发明申请
    DENTAL COMPOSITION 有权
    牙科成分

    公开(公告)号：US20150231040A1

    公开(公告)日：2015-08-20

    申请号：US14704301

    申请日：2015-05-05

    Applicant: Simon STELZIG ,  Joachim E. KLEE ,  Andreas FACHER ,  Christoph WEBER

    Inventor： Simon STELZIG ,  Joachim E. KLEE ,  Andreas FACHER ,  Christoph WEBER

    IPC: A61K6/00

    CPC classification number: A61K6/0091 ,  A61K6/0023 ,  A61K6/08 ,  A61K6/083 ,  A61K6/0835 ,  A61K6/087 ,  A61K6/09 ,  C07C231/02 ,  C08L33/00 ,  C08L75/16 ,  C08L33/10 ,  C07C233/38

    Abstract: Dental composition comprising (i) a particulate filler; (ii) a polymerizable hydrolysis-stable compound of the following formula (1) AXn wherein A is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, which X may be the same or different and are represented by the following formula (2) wherein R1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group or a group —(CH2)m—Z, wherein Z is COOM, OPO3M2, PO3M2, SO3M, and M is independently a hydrogen atom or a metal atom, and m is an integer of from 0 to 6, L is a bond, a C1-6 alkylene group; and n is an integer of at least 1; provided that at least one X cannot be a (meth)acryl group; and (iii) an initiator system.

    Abstract translation: 牙科组合物，其包含（i）颗粒填料; （ii）下式（1）的可聚合水解稳定化合物AXn其中A是至少含有n个氮原子和任选一个或多个酸性基团的连接基团，X是含有可聚合双键并形成酰胺键的部分 与A的氮原子一起，X可以相同或不同，并由下式（2）表示，其中R 1和R 2彼此独立地表示氢原子，C 1-6烷基或基团 - （CH 2）m-Z，其中Z为COOM，OPO3M2，PO3M2，SO3M和M独立地为氢原子或金属原子，m为0-6的整数，L为键，C1-6 亚烷基; n为1以上的整数。 条件是至少一个X不能是（甲基）丙烯酰基; 和（iii）引发剂体系。

    Dental cement composition
    5.
    发明授权
    Dental cement composition 有权

    公开(公告)号：US10117810B2

    公开(公告)日：2018-11-06

    申请号：US13979806

    申请日：2011-10-18

    Applicant: Simon Stelzig ,  Joachim E. Klee ,  Andreas Facher ,  Christoph Weber

    Inventor： Simon Stelzig ,  Joachim E. Klee ,  Andreas Facher ,  Christoph Weber

    IPC: A61K6/083 ,  A61K6/00 ,  A61K6/09 ,  C07C233/09 ,  C07C233/20 ,  C08F122/38

    Abstract: Dental cement composition comprising (i) a particulate filler reactive with a polyacid in a cement reaction; (ii) a water-soluble polymerizable compound of the following formula (1), AXn (1) wherein A is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, which X may be the same or different and are represented by the following formula (2) wherein R1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group or a group —(CH2)m—Z, wherein Z is COOM, OPO3M2, PO3M2, SO3M, and M is independently a hydrogen atom or a metal atom, and m is an integer of from 0 to 6, L is a bond or a C1-6 alkylene group; and n is an integer of at least 1; provided that at least one X cannot be a (meth)acryl group; and (iii) an initiator system; optionally a polyacidic polymer having polymerizable double bonds; and optionally water.

    Dental composition
    6.
    发明授权
    Dental composition 有权

    公开(公告)号：US09603780B2

    公开(公告)日：2017-03-28

    申请号：US13979811

    申请日：2011-10-18

    Applicant: Simon Stelzig ,  Joachim E. Klee ,  Andreas Facher ,  Christoph Weber

    Inventor： Simon Stelzig ,  Joachim E. Klee ,  Andreas Facher ,  Christoph Weber

    IPC: B29C47/92 ,  A61K6/083 ,  A61K6/00 ,  A61K6/02 ,  C07C233/31 ,  C08F290/06 ,  C07C233/20

    CPC classification number: A61K6/083 ,  A61K6/0023 ,  A61K6/0835 ,  C07C233/20 ,  C08L33/00

    Abstract: Dental composition comprising a water-soluble polymerizable compound of the following formula (1): wherein A is a linear or branched linker group represented by the following formula (3), wherein the nitrogen atom of at least two of the termini forms an amide bond with an X moiety; wherein R′ represents a hydrogen atom or a substituted or unsubstituted aliphatic or cycloaliphatic hydrocarbon group, wherein each R may be the same or different L1, L2, and L3 which may be the same or different, independently represent a single bond, or a C2-20 straight-chain, branched or cyclic hydrocarbon group optionally containing from 1 to 6 heteroatoms selected from nitrogen and oxygen in the backbone of the hydrocarbon group, and optionally from 1 to 6 functional groups selected from carboxylic acid groups or a salt thereof, hydroxyl groups, thiol groups and amino groups, and in case a plurality of L1 and L2 are present, each of L1 and L2 may be the same or different; Q1 and Q2, which may be the same or different, independently represent a single bond or a linkage selected from an amide, a urethane, a urea and a thiourea linkage; k is an integer of at least 0, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, wherein each X may be the same or different and are represented by the following formula (2): wherein R1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group or a group —(CH2)m—COOM, wherein M represents a hydrogen atom or a metal atom, m is an integer of from 0 to 6, L is a bond or a C1-6 alkylene group; and n is an integer of at least 2; (ii) an initiator system; optionally a polyacidic polymer; optionally water and/or a water soluble solvent; and optionally a particulate filler.

    DENTAL COMPOSITION
    8.
    发明申请
    DENTAL COMPOSITION 审中-公开
    牙科成分

    公开(公告)号：US20140039088A1

    公开(公告)日：2014-02-06

    申请号：US13979815

    申请日：2011-10-18

    Applicant: Simon Stelzig ,  Joachim E. Klee ,  Andreas Facher ,  Christoph Weber

    Inventor： Simon Stelzig ,  Joachim E. Klee ,  Andreas Facher ,  Christoph Weber

    IPC: A61K6/087 ,  A61K6/083

    CPC classification number: A61K6/0091 ,  A61K6/0023 ,  A61K6/08 ,  A61K6/083 ,  A61K6/0835 ,  A61K6/087 ,  A61K6/09 ,  C07C231/02 ,  C08L33/00 ,  C08L75/16 ,  C08L33/10 ,  C07C233/38

    Abstract: Dental composition comprising (i) a particulate filler; (ii) a polymerizable hydrolysis-stable compound of the following formula (1) AXn wherein A is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, which X may be the same or different and are represented by the following formula (2) wherein R1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group or a group —(CH2)m—Z, wherein Z is COOM, OPO3M2, PO3M2, SO3M, and M is independently a hydrogen atom or a metal atom, and m is an integer of from 0 to 6, L is a bond, a C1-6 alkylene group; and n is an integer of at least 1; provided that at least one X cannot be a (meth)acryl group; and (iii) an initiator system.

    Abstract translation: 牙科组合物，其包含（i）颗粒填料; （ii）下式（1）的可聚合水解稳定化合物AXn其中A是至少含有n个氮原子和任选一个或多个酸性基团的连接基团，X是含有可聚合双键并形成酰胺键的部分 与A的氮原子一起，X可以相同或不同，并由下式（2）表示，其中R 1和R 2彼此独立地表示氢原子，C 1-6烷基或基团 - （CH 2）m Z，其中Z为COOM，OPO3M2，PO3M2，SO3M和M独立地为氢原子或金属原子，m为0-6的整数，L为键，C1-6亚烷基 ; n为1以上的整数。 条件是至少一个X不能是（甲基）丙烯酰基; 和（iii）引发剂体系。

    DENTAL COMPOSITION
    9.
    发明申请
    DENTAL COMPOSITION 有权
    牙科成分

    公开(公告)号：US20140039087A1

    公开(公告)日：2014-02-06

    申请号：US13979811

    申请日：2011-10-18

    Applicant: Simon Stelzig ,  Joachim E. Klee ,  Andreas Facher ,  Christoph Weber

    Inventor： Simon Stelzig ,  Joachim E. Klee ,  Andreas Facher ,  Christoph Weber

    IPC: A61K6/083

    CPC classification number: A61K6/083 ,  A61K6/0023 ,  A61K6/0835 ,  C07C233/20 ,  C08L33/00

    Abstract: Dental composition comprising a water-soluble polymerizable compound of the following formula (1): wherein A is a linear or branched linker group represented by the following formula (3), wherein the nitrogen atom of at least two of the termini forms an amide bond with an X moiety; wherein R′ represents a hydrogen atom or a substituted or unsubstituted aliphatic or cycloaliphatic hydrocarbon group, wherein each R may be the same or different L1, L2, and L3 which may be the same or different, independently represent a single bond, or a C2-20 straight-chain, branched or cyclic hydrocarbon group optionally containing from 1 to 6 heteroatoms selected from nitrogen and oxygen in the backbone of the hydrocarbon group, and optionally from 1 to 6 functional groups selected from carboxylic acid groups or a salt thereof, hydroxyl groups, thiol groups and amino groups, and in case a plurality of L1 and L2 are present, each of L1 and L2 may be the same or different; Q1 and Q2, which may be the same or different, independently represent a single bond or a linkage selected from an amide, a urethane, a urea and a thiourea linkage; k is an integer of at least 0, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, wherein each X may be the same or different and are represented by the following formula (2): wherein R1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group or a group —(CH2)m—COOM, wherein M represents a hydrogen atom or a metal atom, m is an integer of from 0 to 6, L is a bond or a C1-6 alkylene group; and n is an integer of at least 2; (ii) an initiator system; optionally a polyacidic polymer; optionally water and/or a water soluble solvent; and optionally a particulate filler.

    Abstract translation: 1.一种牙科用组合物，其含有下述式（1）所示的水溶性聚合性化合物：式中，A为下述通式（3）所示的直链或支链连接基团，其中，所述末端中的至少2个的氮原子形成酰胺键 与X部分; 其中R'表示氢原子或取代或未取代的脂族或脂环族烃基，其中每个R可以相同或不同，可以相同或不同的L1，L2和L3独立地表示单键，或C2 -20个直链，支链或环状烃基，任选地含有1至6个选自氮原子和氧的杂原子在烃基的主链中，以及任选地1-6个选自羧酸基团或其盐的官能团，羟基 基团，硫醇基和氨基，并且在存在多个L1和L2的情况下，L1和L2中的每一个可以相同或不同; Q1和Q2可以相同或不同，独立地表示单键或选自酰胺，氨基甲酸酯，脲和硫脲键的键; k是至少为0的整数，X是含有可聚合双键并与A的氮原子形成酰胺键的部分，其中每个X可以相同或不同，并由下式（2）表示：其中 R 1和R 2彼此独立地表示氢原子，C 1-6烷基或基团 - （CH 2）m -COOM，其中M表示氢原子或金属原子，m表示0〜 6，L是键或C1-6亚烷基; 且n为至少2的整数; （ii）引发剂体系; 任选的多酸聚合物; 任选的水和/或水溶性溶剂; 和任选的颗粒填料。

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