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    Biostatic polymer formed articles
    2.
    发明授权
    Biostatic polymer formed articles 有权
    生物静电聚合物成型制品

    公开(公告)号：US09179669B2

    公开(公告)日：2015-11-10

    申请号：US11883519

    申请日：2006-02-02

    申请人： Steven Kritzler

    发明人： Steven Kritzler

    IPC分类号： A01N33/12 ,  C08K5/00 ,  C08K5/19 ,  C09D129/04

    CPC分类号： A01N33/12 ,  C08K5/0058 ,  C08K5/19 ,  C09D129/04 ,  A01N25/10 ,  A01N25/24 ,  A01N2300/00 ,  C08L29/04 ,  A01N25/34

    摘要： Compositions comprising a polyvinyl alcohol in combination with a biocide which is a plasticizer, such as a quaternary ammonium compound, or in combination with a biocide and a compatible plasticizer, and wherein the biocide forms a complex with the polyvinyl alcohol, said combination having been heated to above its melting point, said composition having a surface which remains biostatic or biocidal for at least 7 days. A hot melt of the composition may be cast or applied as a film or coating or may be extruded molded or otherwise into articles. Volatiles formed during heating may be removed from the combination e.g. by low pressure.

    摘要翻译： 包含聚乙烯醇与作为增塑剂的杀生物剂如季铵化合物或与杀生物剂和相容的增塑剂组合的组合物，并且其中所述杀生物剂与聚乙烯醇形成络合物，所述组合已被加热 至高于其熔点，所述组合物具有保持生物静态或杀生物剂至少7天的表面。 组合物的热熔体可以作为膜或涂层浇铸或施加，或者可以挤出成型或以其它方式挤压成型。 在加热过程中形成的挥发物可以从组合物中除去。 通过低压。

    Drip tray tablet
    3.
    发明授权
    Drip tray tablet 有权
    滴纸盘片

    公开(公告)号：US08795740B2

    公开(公告)日：2014-08-05

    申请号：US10576862

    申请日：2004-10-20

    申请人： Steven Kritzler ,  Alex Sava

    发明人： Steven Kritzler ,  Alex Sava

    IPC分类号： A01N59/14 ,  A01N59/00 ,  C02F3/00 ,  C02F1/00 ,  C02F1/68 ,  C11D9/16

    CPC分类号： F24F13/22 ,  A01N63/02 ,  A61L2/23 ,  C02F1/50 ,  C02F3/34 ,  C02F2305/14 ,  F24F2003/1678 ,  F24F2013/227 ,  A01N59/14 ,  A01N35/08 ,  A01N25/34 ,  A01N2300/00

    摘要： A tablet for use in a drip tray including an excipient selected so that the tablet will not fully dissolve in water at ambient temperature for a period of at least one month, more preferably up to 12 months, a biocide, at least one enzyme, preferably a proteolytic or hydrolase enzyme, and enzyme preserving means, such as a boron compound for maintaining enzyme activity in a moist environment. The excipient may be for example poly vinyl alcohols, high molecular weight polyethylene glycols, high molecular weight polypropylene glycols, esters or partial esters of polyethylene glycols or of polypropylene glycols, and high molecular weight thermoplastic surfactants. The invention also relates to methods for inhibiting the growth of biofilm in an drip tray or the like, including the step of adding to the tray a tablet according to the invention.

    摘要翻译： 一种用于包括赋形剂的滴液盘的片剂，其选择为使得片剂在环境温度下不会完全溶解在水中至少一个月，更优选至多12个月的时间，杀生物剂，至少一种酶，优选地 蛋白水解酶或水解酶，以及酶保存装置，例如在潮湿环境中保持酶活性的硼化合物。 赋形剂可以是例如聚乙烯醇，高分子量聚乙二醇，高分子量聚丙二醇，聚乙二醇或聚丙二醇的酯或偏酯，以及高分子量热塑性表面活性剂。 本发明还涉及抑制滴落盘等中生物膜生长的方法，包括向托盘中加入根据本发明的片剂的步骤。

    Biofilm growth prevention
    4.
    发明申请
    Biofilm growth prevention 有权
    生物膜生长预防

    公开(公告)号：US20070004596A1

    公开(公告)日：2007-01-04

    申请号：US10557617

    申请日：2004-05-18

    申请人： Steven Kritzler

    发明人： Steven Kritzler

    IPC分类号： A01N25/10 ,  A61K31/05 ,  A01N31/08

    CPC分类号： A01N25/00 ,  A01N25/10 ,  A61L2/18 ,  A61L2/232 ,  C09D5/024 ,  C09D5/14 ,  A01N31/08 ,  A01N31/12 ,  A01N31/14 ,  A01N31/16

    摘要： A biostatic coating comprising a coating composition which on drying produces an intrinsically hydrophobic film. The coating composition includes a biocidal complex A-B in which A is a phenolic biocide and B is selected from polyvinylpyrrolidone (“PVP”), PVP polymers, PVP copolymers and mixtures thereof. The coating composition for example is selected from acrylic and methacrylic polymer based compositions, acrylic and methacrylic copolymer based compositions, vinyl polymer based compositions, vinyl copolymer based compositions, epoxy resins, epoxy esters, and mixtures thereof. Suitable biocides for use in the invention include, but are not limited to complexes of PVP or PVP copolymer with triclosan; diclosan; dichlorophen; orthophenylphenol; orthobenzylparachlorophenol, cresols, xylols, and substituted diphenyl ethers.

    摘要翻译： 一种生物静电涂层，其包含在干燥时产生本征性疏水膜的涂料组合物。 涂料组合物包括杀生物复合物A-B，其中A是酚类杀生物剂，B选自聚乙烯吡咯烷酮（“PVP”），PVP聚合物，PVP共聚物及其混合物。 涂料组合物例如选自丙烯酸和甲基丙烯酸聚合物基组合物，基于丙烯酸和甲基丙烯酸共聚物的组合物，基于乙烯基聚合物的组合物，基于乙烯基共聚物的组合物，环氧树脂，环氧酯及其混合物。 用于本发明的合适的杀生物剂包括但不限于PVP或PVP共聚物与三氯生的络合物; 双氯酚 二氯酚 邻苯基苯酚 邻苯基对氯苯酚，甲酚，二甲苯胺和取代的二苯醚。

    Prion disinfection
    6.
    发明授权
    Prion disinfection 有权
    朊病毒消毒

    公开(公告)号：US09480761B2

    公开(公告)日：2016-11-01

    申请号：US10467591

    申请日：2002-01-31

    申请人： Steven Kritzler ,  Alex Sava ,  Michael Zalunardo

    发明人： Steven Kritzler ,  Alex Sava ,  Michael Zalunardo

    IPC分类号： C12N1/22 ,  C12N1/20 ,  A61L2/12 ,  A01N63/00 ,  A61L2/00 ,  A61L2/025 ,  A61L2/08 ,  A61L2/16

    CPC分类号： A61L2/12 ,  A01N63/00 ,  A61L2/0082 ,  A61L2/025 ,  A61L2/085 ,  A61L2/16 ,  A61L2202/24

    摘要： The invention relates to a methods and compositions for treating a surface, suspension or solution contaminated with a PrPSc prion protein or a surrogate thereof. The methods and compositions employ a combination of one or more enzymes effective to cleave a prion protein to fragments having a non-infective molecular weight, and one or more agents selected to favor conformational unfolding of the PrPSc prion protein while not denaturing the one or more enzymes.

    摘要翻译： 本发明涉及用于处理被PrPSc朊蛋白或其替代物污染的表面，悬浮液或溶液的方法和组合物。 所述方法和组合物采用有效将朊病毒蛋白切割成具有非感染性分子量的片段的一种或多种酶的组合，以及一种或多种选择用于促进PrPSc朊病毒蛋白构象展开的试剂，而不使所述一种或多种 酶。

    Low foaming cleaner
    7.
    发明授权
    Low foaming cleaner 有权
    低泡沫清洁剂

    公开(公告)号：US09023778B2

    公开(公告)日：2015-05-05

    申请号：US12374157

    申请日：2007-07-18

    申请人： Steven Kritzler ,  Alex Sava

    发明人： Steven Kritzler ,  Alex Sava

    IPC分类号： C11D3/20 ,  C11D3/00 ,  C11D17/00 ,  C11D17/08 ,  C11D7/42 ,  C11D3/386 ,  C11D3/48 ,  C11D7/34 ,  C11D7/50 ,  C11D11/00 ,  C11D7/26

    CPC分类号： C11D3/38618 ,  C11D3/0026 ,  C11D3/48 ,  C11D7/263 ,  C11D7/34 ,  C11D7/5022 ,  C11D11/0041

    摘要： Liquid compositions for cleaning, in particular medical instruments and air conditioning surfaces, said composition excluding surfactants and comprising one or more enzymes including a protease and optionally a hydrolase, a solvent system including a water soluble glycol ether solvent, at least one anionic hydrotrope, and wherein the molar ratio of said at least one hydrotrope to said glycol ether in the composition is selected to preserve the activity of said one or more enzymes. The hydrotrope is advantageously an anionic hydrotrope selected from the group consisting of water soluble anionic hydrotropes of the formula (I) and having no alkyl side chain greater than six carbons in length, for example a xylene sulfonate or cumene sulfonate salt.

    摘要翻译： 用于清洁的液体组合物，特别是医疗仪器和空调表面，所述组合物不包括表面活性剂，并且包含一种或多种酶，包括蛋白酶和任选的水解酶，溶剂体系，包括水溶性二醇醚溶剂，至少一种阴离子水溶助长剂和 其中选择所述组合物中所述至少一种水溶助长剂与所述二醇醚的摩尔比以保持所述一种或多种酶的活性。 水溶助长剂有利地是选自由式（I）的水溶性阴离子水溶助长剂组成的组的阴离子水溶助长剂，并且不具有大于六个碳原子的烷基侧链，例如二甲苯磺酸盐或枯烯磺酸盐。

    Prion Disinfection
    8.
    发明申请
    Prion Disinfection 审中-公开
    朊病毒消毒

    公开(公告)号：US20110086414A1

    公开(公告)日：2011-04-14

    申请号：US12965697

    申请日：2010-12-10

    申请人： Steven Kritzler ,  Alex Sava ,  Michael Zalunardo

    发明人： Steven Kritzler ,  Alex Sava ,  Michael Zalunardo

    IPC分类号： C12S9/00 ,  C12S99/00 ,  C12N9/50

    CPC分类号： A61L2/12 ,  A01N63/00 ,  A61L2/0082 ,  A61L2/025 ,  A61L2/085 ,  A61L2/16 ,  A61L2202/24

    摘要： The invention relates to a methods and compositions for treating a surface, suspension or solution contaminated with a PrPSc prion protein or a surrogate thereof. The methods and compositions employ a combination of one or more enzymes effective to cleave a prion protein to fragments having a non-infective molecular weight, and one or more agents selected to favour conformational unfolding of the PrPSc prion protein while not denaturing the one or more enzymes.

    摘要翻译： 本发明涉及用于处理被PrPSc朊蛋白或其替代物污染的表面，悬浮液或溶液的方法和组合物。 所述方法和组合物采用有效将朊病毒蛋白切割成具有非感染性分子量的片段的一种或多种酶的组合，以及一种或多种选择用于促进PrPSc朊病毒蛋白构象展开的试剂，而不使所述一种或多种 酶。

    Low Foaming Cleaner
    9.
    发明申请
    Low Foaming Cleaner 有权
    低发泡清洁剂

    公开(公告)号：US20100009884A1

    公开(公告)日：2010-01-14

    申请号：US12374157

    申请日：2007-07-18

    申请人： Steven Kritzler ,  Alex Sava

    发明人： Steven Kritzler ,  Alex Sava

    IPC分类号： C11D3/386

    CPC分类号： C11D3/38618 ,  C11D3/0026 ,  C11D3/48 ,  C11D7/263 ,  C11D7/34 ,  C11D7/5022 ,  C11D11/0041

    摘要： Liquid compositions for cleaning, in particular medical instruments and air conditioning surfaces, said composition excluding surfactants and comprising one or more enzymes including a protease and optionally a hydrolase, a solvent system including a water soluble glycol ether solvent, at least one anionic hydrotrope, and wherein the molar ratio of said at least one hydrotrope to said glycol ether in the composition is selected to preserve the activity of said one or more enzymes. The hydrotrope is advantageously an anionic hydrotrope selected from the group consisting of water soluble anionic hydrotropes of the formula (I) and having no alkyl side chain greater than six carbons in length, for example a xylene sulfonate or cumene sulfonate salt.

    摘要翻译： 用于清洁的液体组合物，特别是医疗仪器和空调表面，所述组合物不包括表面活性剂，并且包含一种或多种酶，包括蛋白酶和任选的水解酶，溶剂体系，包括水溶性二醇醚溶剂，至少一种阴离子水溶助长剂和 其中选择所述组合物中所述至少一种水溶助长剂与所述二醇醚的摩尔比以保持所述一种或多种酶的活性。 水溶助长剂有利地是选自由式（I）的水溶性阴离子水溶助长剂组成的组的阴离子水溶助长剂，并且不具有大于六个碳原子的烷基侧链，例如二甲苯磺酸盐或枯烯磺酸盐。