Reverse transcriptase having improved thermostability
    2.
    发明授权
    Reverse transcriptase having improved thermostability 有权
    逆转录酶具有改善的热稳定性

    公开(公告)号:US09534210B2

    公开(公告)日:2017-01-03

    申请号:US13984746

    申请日:2012-02-07

    Abstract: The present invention relates to a reverse transcriptase having improved thermostability, more precisely a mutant reverse transcriptase with improved thermostability by substitution of one or more amino acids selected from the group consisting of the 63rd glutamine (Q63), the 264th lysine (K264), the 295th lysine (K295), the 306th threonine (T306), the 346th glutamic acid (E346), the 408th proline (P408), the 438th histidine (H438), and the 454th asparagin (N454) of the amino acid sequence of M-MLV originated reverse transcriptase represented by SEQ. ID. NO: 1 with other amino acids. The mutant reverse transcriptase of the present invention demonstrates excellent thermostability, compared with the wild type reverse transcriptase. Therefore, it is advantageous to obtain the target cDNA with stable reverse transcription activity even in the presence of RNA that can form the stable secondary structure at a high temperature.

    Abstract translation: 本发明涉及具有改善的热稳定性的逆转录酶,更准确地说,具有通过取代选自第63位谷氨酰胺(Q63),第264位赖氨酸(K264), 第309位赖氨酸(K295),第306位苏氨酸(T306),第346位谷氨酸(E346),第408位脯氨酸(P408),第438位组氨酸(H438)和第454位天门冬酰胺(N454) MLV起源于SEQ ID NO: ID。 NO:1与其他氨基酸。 与野生型逆转录酶相比,本发明的突变型逆转录酶表现出优异的热稳定性。 因此,即使在能够在高温下形成稳定的二级结构的RNA的存在下,也可以获得具有稳定的逆转录活性的靶cDNA。

    Method for performing mobility in a wireless communication system and apparatus for the same
    4.
    发明授权
    Method for performing mobility in a wireless communication system and apparatus for the same 有权
    在无线通信系统中执行移动性的方法及其装置

    公开(公告)号:US09344944B2

    公开(公告)日:2016-05-17

    申请号:US14009950

    申请日:2012-04-04

    CPC classification number: H04W36/30 H04W36/0083 H04W36/04

    Abstract: A method for performing mobility by a user equipment (UE) in a wireless communication system is provided. The method includes: receiving a report configuration from a serving cell, the report configuration including detection basis information; detecting whether a cell is present based on the detection basis information; transmitting, by the UE, a detection report reporting the detected cell is present to the serving cell; receiving a measurement configuration used for measuring the detected cell from the serving cell; measuring the cell based on the measurement configuration; and performing mobility with the cell.

    Abstract translation: 提供了一种用于在无线通信系统中由用户设备(UE)执行移动性的方法。 该方法包括:从服务小区接收报告配置,该报告配置包括检测基础信息; 基于检测基准信息检测单元是否存在; 由所述UE向所述服务小区发送报告所检测到的小区的检测报告; 从所述服务小区接收用于测量所检测到的小区的测量配置; 基于测量配置测量单元; 并与该小区一起执行移动性。

    Method for reporting system information in wireless communication system and apparatus for supporting same
    8.
    发明授权
    Method for reporting system information in wireless communication system and apparatus for supporting same 有权
    用于在无线通信系统中报告系统信息的方法和用于支持其的装置

    公开(公告)号:US09258746B2

    公开(公告)日:2016-02-09

    申请号:US14232568

    申请日:2012-07-13

    Abstract: A method for a terminal reporting system information in a wireless communication system is disclosed. The method comprises: receiving a system information report request of a neighboring cell from a serving cell; and transmitting a system information report to the serving cell as a response to the system information report request. If the terminal has system information that is obtained in advance of the neighboring cell that is obtained before receiving the system information report request, the system information report comprises the system information that is obtained in advance and validity information on the system information that is obtained in advance.

    Abstract translation: 公开了一种在无线通信系统中终端报告系统信息的方法。 该方法包括:从服务小区接收相邻小区的系统信息报告请求; 以及作为对所述系统信息报告请求的响应,向所述服务小区发送系统信息报告。 如果终端具有在接收系统信息报告请求之前获得的相邻小区之前获得的系统信息,则系统信息报告包括预先获得的系统信息和关于系统信息的有效性信息 提前。

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