公开(公告)号：US08860097B2

公开(公告)日：2014-10-14

申请号：US13701610

申请日：2011-06-14

申请人： Takuya Higuchi ,  Tomonori Akai ,  Katsuyuki Motai

发明人： Takuya Higuchi ,  Tomonori Akai ,  Katsuyuki Motai

IPC分类号： H01L29/66 ,  H01L29/78 ,  G01N27/414

CPC分类号： H01L29/78 ,  G01N27/4145

摘要： Provided is a biosensor that makes it possible to detect the electrical properties of a bio-related material contained in an analyte fluid such as an aqueous solution placed on a sensitive membrane and to observe the bio-related material at a high magnification with an observation device such as a microscope. The biosensor comprises: a substrate 10, a transparent semiconductor film 20 laminated on the substrate 10, a source electrode 30a and a drain electrode 30b formed at both ends of the transparent semiconductor film 20, an insulating film 40 laminated so as to cover the transparent semiconductor film 20 and the source electrode 30a and the drain electrodes 30b, a sensitive membrane 50 laminated on the insulating film 40, and a partition 60 that is formed at both ends of the sensitive membrane 50 to retain an analyte fluid 100, such as an aqueous solution or liquid culture containing a sample, on the sensitive membrane 50 and to retain the analyte fluid 100 in a specific region so that the bio-related material 200 can be placed on the sensitive membrane 50.

摘要翻译： 提供了一种生物传感器，其可以检测包含在诸如放置在敏感膜上的水溶液的分析物流体中的生物相关材料的电性能，并且用观察装置高倍率观察生物相关材料 如显微镜。 生物传感器包括：基板10，层叠在基板10上的透明半导体膜20，形成在透明半导体膜20的两端的源电极30a和漏极30b，层叠以覆盖透明半导体膜20的绝缘膜40 半导体膜20以及源电极30a和漏电极30b，层压在绝缘膜40上的敏感膜50以及形成在敏感膜50的两端以保持分析物流体100的分隔件60，例如 含有样品的水溶液或液体培养物在敏感膜50上并将分析物流体100保持在特定区域中，使得生物相关材料200可以放置在敏感膜50上。

公开(公告)号：US20130210068A1

公开(公告)日：2013-08-15

申请号：US13878726

申请日：2010-12-06

申请人： Naoki Yokoyama ,  Tomonori Akai ,  Yuya Takasugi

发明人： Naoki Yokoyama ,  Tomonori Akai ,  Yuya Takasugi

IPC分类号： C12Q1/04

CPC分类号： C12Q1/04 ,  C12Q1/045

摘要： This invention provides a means for cell migration assays by regulating the cells adhered to a substrate so that they migrate to a given region, which is a substrate used for cell culture comprising: a base material comprising a conductive region and an insulating region provided thereon and cell-adhesive regions and non-cell-adhesive regions provided in the conductive region and the insulating region, respectively, wherein a cell-adhesive region is positioned adjacent to a non-cell-adhesive region in the conductive region, and a cell-adhesive region is positioned adjacent to a non-cell-adhesive region in the insulating region.

摘要翻译： 本发明提供了一种用于细胞迁移测定的方法，其通过调节附着于基底的细胞使得它们迁移到给定区域，所述给定区域是用于细胞培养的底物，其包含：基材，其包含导电区域和设置在其上的绝缘区域， 设置在导电区域和绝缘区域中的细胞粘附区域和非细胞粘合剂区域，其中细胞粘附区域邻近导电区域中的非细胞粘附区域定位，并且细胞粘合剂 区域与绝缘区域中的非细胞粘合剂区域相邻。

公开(公告)号：US20100258789A1

公开(公告)日：2010-10-14

申请号：US12680638

申请日：2008-09-26

申请人： Tomonori Akai ,  Yasuhiro Iizumi

发明人： Tomonori Akai ,  Yasuhiro Iizumi

IPC分类号： H01L51/50

CPC分类号： H05B33/14 ,  C09K11/025 ,  C09K11/883

摘要： The present invention provides an EL device that contains a quantum-dots-containing layer in which quantum dots hardly coagulate even under high-temperature conditions, e.g., at a temperature of 90° C. or more, that has a good performance even if heat treatment was carried at a high temperature in its production process, that can retain its emission characteristics for a prolonged period of time, and that has high durability.An electroluminescent device comprises a pair of electrodes, and an electroluminescent layer containing at least a luminescent layer, situated between the electrodes. The luminescent layer contains quantum dots whose surfaces are protected by one or more protective materials. At least one of the protective materials has a glass transition temperature and a melting point of 90° C. or more.

摘要翻译： 本发明提供一种EL器件，其含有量子点含量层，即使在高温条件下（例如在90℃以上的温度下）也能量子点难以凝固，即使在热 在其生产过程中在高温下进行处理，其可以长时间保持其排放特性，并且具有高耐久性。 电致发光器件包括一对电极和位于电极之间的至少包含发光层的电致发光层。 发光层含有量子点，其表面被一种或多种保护材料保护。 保护材料中的至少一种具有玻璃化转变温度和90℃以上的熔点。

公开(公告)号：US20080122353A1

公开(公告)日：2008-05-29

申请号：US11772954

申请日：2007-07-03

申请人： Tomonori AKAI ,  Shigehiro UENO

发明人： Tomonori AKAI ,  Shigehiro UENO

IPC分类号： H01J1/62 ,  H01J9/02

CPC分类号： H01L51/5234 ,  H01L51/0037 ,  H01L51/0043 ,  H01L51/5048

摘要： An object of the present invention is to provide an EL element, which is with a problem of the EL layer deterioration caused at the time of forming a cathode layer on an EL layer resolved, and without the decline of the original functions; and a production method suitable for producing such an EL element. The object has been achieved by providing an EL element having a lamination structure with an anode layer, an EL layer, a charge transporting protection layer and a cathode layer formed in this order on a substrate, and by using a hole transporting material such as TPD for the charge transporting protection layer.

摘要翻译： 本发明的目的是提供一种EL元件，其具有在EL层上形成阴极层时引起的EL层劣化的问题，并且不会降低原来的功能; 以及适于制造这种EL元件的制造方法。 该目的已经通过提供具有层叠结构的EL元件来实现，该EL元件具有在基板上依次形成的阳极层，EL层，电荷输送保护层和阴极层，并且通过使用诸如TPD的空穴传输材料 用于电荷传输保护层。

公开(公告)号：US20080038584A1

公开(公告)日：2008-02-14

申请号：US11835536

申请日：2007-08-08

申请人： Tomonori AKAI

发明人： Tomonori AKAI

IPC分类号： B32B9/00

CPC分类号： H01L51/5262 ,  H01L51/524 ,  H01L51/5253 ,  H05B33/04 ,  H05B33/22 ,  H05B33/28

摘要： A main object of the present invention is to provide an organic EL element having high chromatic purity and excellent display quality. To achieve the object, the present invention provides an organic electroluminescence element comprising: a transparent substrate; a transparent or semitransparent-first electrode layer formed on the transparent substrate; an organic EL layer formed on the transparent or semitransparent-first electrode layer and containing at least a light emitting layer; a semitransparent-second electrode layer formed on the organic EL layer; a transparent or semitransparent-optical path length adjusting layer formed on the semitransparent-second electrode layer and made of an inorganic material; and a reflecting layer formed on the transparent or semitransparent-optical path length adjusting layer.

摘要翻译： 本发明的主要目的是提供一种色纯度高，显示质量优异的有机EL元件。 为了实现该目的，本发明提供一种有机电致发光元件，包括：透明基板; 形成在透明基板上的透明或半透明第一电极层; 形成在所述透明或半透明第一电极层上并且至少含有发光层的有机EL层; 形成在有机EL层上的半透明第二电极层; 形成在半透明第二电极层上并由无机材料制成的透明或半透明光路长度调节层; 以及形成在透明或半透明光路长度调节层上的反射层。

公开(公告)号：US07714505B2

公开(公告)日：2010-05-11

申请号：US11772954

申请日：2007-07-03

申请人： Tomonori Akai ,  Shigehiro Ueno

发明人： Tomonori Akai ,  Shigehiro Ueno

IPC分类号： H01J63/04

CPC分类号： H01L51/5234 ,  H01L51/0037 ,  H01L51/0043 ,  H01L51/5048

摘要： An object of the present invention is to provide an EL element, which is with a problem of the EL layer deterioration caused at the time of forming a cathode layer on an EL layer resolved, and without the decline of the original functions; and a production method suitable for producing such an EL element. The object has been achieved by providing an EL element having a lamination structure with an anode layer, an EL layer, a charge transporting protection layer and a cathode layer formed in this order on a substrate, and by using a hole transporting material such as TPD for the charge transporting protection layer.

摘要翻译： 本发明的目的是提供一种EL元件，其具有在EL层上形成阴极层时引起的EL层劣化的问题，并且不会降低原来的功能; 以及适于制造这种EL元件的制造方法。 该目的已经通过提供具有层叠结构的EL元件来实现，该EL元件具有在基板上依次形成的阳极层，EL层，电荷输送保护层和阴极层，并且通过使用诸如TPD的空穴传输材料 用于电荷传输保护层。

公开(公告)号：US06650464B2

公开(公告)日：2003-11-18

申请号：US10054693

申请日：2002-01-24

申请人： Tomonori Akai

发明人： Tomonori Akai

IPC分类号： G02F129

CPC分类号： H01L51/0013 ,  H01L27/32

摘要： A laser processing device comprising: an optical system having a laser beam source, and an air-tight chamber provided separately from the optical system, wherein the chamber has a transparent portion for transmitting a laser beam emitted from the laser beam source, on a light-receptive face thereof receiving the laser beam, the chamber is capable of accommodating a donor substrate on which an organic substance layer including at least a luminous layer to be transferred is formed and an acceptor substrate onto which the organic substance layer is transferred from the donor substrate by the laser beam transmitted through the transparent portion, and the inside of the air-tight chamber is in an inert gas atmosphere or in a vacuum atmosphere.

公开(公告)号：US09163274B2

公开(公告)日：2015-10-20

申请号：US13807346

申请日：2011-06-30

申请人： Tomonori Akai ,  Kei Imai ,  Yoshio Aikawa ,  Masaki Ohtake ,  Satoshi Sugimura

发明人： Tomonori Akai ,  Kei Imai ,  Yoshio Aikawa ,  Masaki Ohtake ,  Satoshi Sugimura

IPC分类号： C12Q1/04 ,  A61B17/435 ,  A01K67/027 ,  C12N5/073 ,  C12M3/00 ,  C12M1/34 ,  C12M1/36

CPC分类号： G06T7/0016 ,  A01K67/027 ,  A01K2227/101 ,  A61B17/435 ,  C12M21/06 ,  C12M41/46 ,  C12M41/48 ,  C12N5/0604 ,  C12Q1/04 ,  G01N33/4833 ,  G06T2207/10016 ,  G06T2207/30044

摘要： An object of the present invention is to provide a means for efficiently obtaining mammalian embryos having high conception rates. A first aspect of the present invention is a method for selecting a mammalian embryo prepared by in vitro culture from a fertilized egg, comprising a step of selecting an embryo using two or more of the following indicators: the time from fertilization to the completion of first cleavage; the morphology at a stage after first cleavage and before second cleavage; the morphology at a stage after third cleavage and before fourth cleavage; and the amount of oxygen consumed at the early blastocyst stage, the blastocyst stage, or the expanded blastocyst stage.

摘要翻译： 本发明的目的是提供一种有效地获得具有高受孕率的哺乳动物胚胎的方法。 本发明的第一方面是一种选择通过从受精卵进行体外培养而制备的哺乳动物胚胎的方法，其包括使用以下两个或更多个指标来选择胚胎的步骤：从受精到完成第一次的时间 裂解 在第一次切割后和第二次切割之前的阶段的形态; 在第三次切割后和第四次切割之前的阶段的形态; 以及早期胚泡期，胚泡期或扩大胚泡期消耗的氧量。

公开(公告)号：US08685328B2

公开(公告)日：2014-04-01

申请号：US13060700

申请日：2009-05-21

申请人： Hiroaki Okano ,  Kazuo Nishikawa ,  Hisaharu Yagi ,  Norihiro Matsuoka ,  Tomonori Akai ,  Misaki Nakamura ,  Yoshihiro Shimizu

发明人： Hiroaki Okano ,  Kazuo Nishikawa ,  Hisaharu Yagi ,  Norihiro Matsuoka ,  Tomonori Akai ,  Misaki Nakamura ,  Yoshihiro Shimizu

IPC分类号： A62B7/08 ,  A61L2/00 ,  A61L9/00 ,  C25B5/00 ,  H05F3/00

CPC分类号： A61L9/22 ,  A61L2202/14 ,  A61L2202/25 ,  F24F3/166 ,  F24F2001/0096 ,  F24F2003/1682

摘要： In order to remove a pathogenic effect of a microorganism in a room or a work space in a short period of time, an ion diffusing apparatus, which includes an ion generator (17, 18) for generating positive ions each including H+(H2O)m and negative ions each including O2−(H2O)n, where m and n are arbitrary integers, and a blower for delivering the positive ions and the negative ions, which are generated from the ion generator (17), from a blowout opening, is operated to widely distribute, with a high concentration, the positive ions and the negative ions in the room.

摘要翻译： 为了在短时间内除去微生物在室内或工作空间中的致病作用，可以使用离子扩散装置，该离子扩散装置包括用于产生正离子的离子发生器（17,18），每个离子发生器包括H +（H 2 O）m 和负离子各自包括O 2 - （H 2 O）n，其中m和n是任意整数，并且用于从吹出口从离子发生器（17）输出正离子和负离子的鼓风机是 以高浓度广泛分布室内的正离子和负离子。

公开(公告)号：US20130244328A1

公开(公告)日：2013-09-19

申请号：US13990642

申请日：2010-12-06

申请人： Naoki Yokoyama ,  Tomonori Akai

发明人： Naoki Yokoyama ,  Tomonori Akai

IPC分类号： C12N5/00

CPC分类号： C12N5/0068 ,  C12M25/08 ,  C12M33/00 ,  C12N2529/00 ,  C12N2539/10

摘要： This invention provides a means for modifying surface properties of a cell culture substrate under specific conditions, to thereby regulate regions to which cells are allowed to adhere or are not allowed to adhere, depending on cell type. This invention relates to a method of cell culture comprising steps of: applying a positive potential to a conductive region of a substrate comprising a base material having a conductive region and a non-cell-adhesive membrane coupled thereto with the aid of silane, so as to separate the non-cell-adhesive membrane from the substrate; and culturing cells in a region from which the non-cell-adhesive membrane has been separated.

摘要翻译： 本发明提供了在特定条件下修饰细胞培养基质的表面特性的方法，根据细胞种类，调节允许细胞粘附或不允许粘附的区域。 本发明涉及一种细胞培养方法，其包括以下步骤：借助于硅烷将正电位施加到包括具有导电区域的基底材料和与其偶联的非细胞粘附膜的基底的导电区域，以便 以将非细胞粘附膜与基底分离; 并在非细胞粘附膜分离的区域中培养细胞。