SYSTEMS AND METHODS FOR EXERTING FORCE ON BODIES

    公开(公告)号:US20210346235A1

    公开(公告)日:2021-11-11

    申请号:US17384968

    申请日:2021-07-26

    Abstract: Systems and methods for exerting forces on a body, including a support structure defining a space and a plurality of surface contacting units that are configured to exert force upon the body, such that the weight is distributed away from the primary weight bearing regions to non-weight bearing regions of the body, or vice versa, without exerting significant shear or frictional forces on surfaces of the body. The systems and methods may be used to exert forces to cause fluid shift in different compartments of the body. Applications include treatment of various disease conditions including pressure ulcers, heart failure, high blood pressure, preeclampsia, osteoporosis, injuries of spine and to slow microgravity-induced bone and muscle loss. The systems and methods may be used to simulate gravity, weightlessness or buoyancy, in rehabilitation medicine. The system may include a chair, bed, a wearable suit or an exoskeleton.

    METHODS AND COMPOSITIONS FOR TREATING TYPE 2 DIABETES AND RELATED CONDITIONS
    4.
    发明申请
    METHODS AND COMPOSITIONS FOR TREATING TYPE 2 DIABETES AND RELATED CONDITIONS 审中-公开
    用于治疗2型糖尿病的方法和组合物及相关条件

    公开(公告)号:US20140178456A1

    公开(公告)日:2014-06-26

    申请号:US14194813

    申请日:2014-03-02

    CPC classification number: A61K31/4439 A61K9/0024 A61K47/14 A61K47/22 A61K47/34

    Abstract: In some embodiments, there are provided methods and compositions for treating, preventing, or delaying the onset of type 2 diabetes and related disorders. The methods comprise administering a sustained release composition comprising a peroxisome proliferator-activated receptor (PPAR) agonist subcutaneously in a localized area of the subject. Slow release of the PPAR agonist in situ enhances the metabolic activity of subcutaneous adipose tissue, resulting in an increased ability of the tissue to clear excess glucose and lipid from the blood stream, while minimizing adverse side-effects of the agonist.

    Abstract translation: 在一些实施方案中,提供了用于治疗,预防或延迟2型糖尿病和相关病症发作的方法和组合物。 所述方法包括在受试者的局部区域中皮下投与包含过氧化物酶体增殖物激活受体(PPAR)激动剂的持续释放组合物。 PPAR激动剂的缓慢释放原位增强皮下脂肪组织的代谢活性,导致组织从血液中清除过量的葡萄糖和脂质的能力增加,同时最小化激动剂的不利副作用。

    Systems and methods for exerting force on bodies

    公开(公告)号:US10265237B2

    公开(公告)日:2019-04-23

    申请号:US14772359

    申请日:2014-03-06

    Abstract: Systems and methods for exerting forces on a body, including a support structure defining a space and a plurality of surface contacting units that are configured to exert force upon the body, such that the weight is distributed away from the primary weight bearing regions to non-weight bearing regions of the body, or vice versa, without exerting significant shear or frictional forces on surfaces of the body. The systems and methods may be used to exert forces to cause fluid shift in different compartments of the body. Applications include treatment of various disease conditions including pressure ulcers, heart failure, high blood pressure, preeclampsia, osteoporosis, injuries of spine and to slow microgravity-induced bone and muscle loss. The systems and methods may be used to simulate gravity, weightlessness or buoyancy, in rehabilitation medicine. The system may include a chair, bed, a wearable suit or an exoskeleton.

    Systems and methods for exerting force on bodies

    公开(公告)号:US11071678B2

    公开(公告)日:2021-07-27

    申请号:US16391169

    申请日:2019-04-22

    Abstract: Systems and methods for exerting forces on a body, including a support structure defining a space and a plurality of surface contacting units that are configured to exert force upon the body, such that the weight is distributed away from the primary weight bearing regions to non-weight bearing regions of the body, or vice versa, without exerting significant shear or frictional forces on surfaces of the body. The systems and methods may be used to exert forces to cause fluid shift in different compartments of the body. Applications include treatment of various disease conditions including pressure ulcers, heart failure, high blood pressure, preeclampsia, osteoporosis, injuries of spine and to slow microgravity-induced bone and muscle loss. The systems and methods may be used to simulate gravity, weightlessness or buoyancy, in rehabilitation medicine. The system may include a chair, bed, a wearable suit or an exoskeleton.

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