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43 条记录 (耗时 0.031 秒)

    Polymerase chain reaction apparatus
    1.
    发明授权
    Polymerase chain reaction apparatus 有权
    聚合酶链反应装置

    公开(公告)号：US08663976B2

    公开(公告)日：2014-03-04

    申请号：US13039630

    申请日：2011-03-03

    申请人： Won-seok Chung ,  Kak Namkoong ,  Joon-ho Kim

    发明人： Won-seok Chung ,  Kak Namkoong ,  Joon-ho Kim

    IPC分类号： C12M1/34 ,  C12M3/00

    CPC分类号： B01L9/527 ,  B01L3/502715 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/147 ,  B01L2300/1827

    摘要： A polymerase chain reaction (“PCR”) apparatus includes a PCR chip holder which accommodates and supports a PCR chip, a housing which supports ends of the PCR chip holder, a temperature control element which moves perpendicularly with respect to the PCR chip holder in a space between the housing and the PCR chip holder in the housing, and an elastic unit which elastically biases the temperature control element toward the PCR chip holder, between the temperature control element and the housing. The temperature control element includes a top surface which is selectively contacted to a bottom surface of the PCR chip.

    摘要翻译： 聚合酶链式反应（“PCR”）装置包括：一个PCR芯片保持器，其容纳和支持PCR芯片;支撑PCR芯片保持器端部的壳体;一个相对于PCR芯片保持器垂直移动的温度控制元件 壳体和壳体中的PCR芯片保持器之间的空间以及在温度控制元件和壳体之间弹性地将温度控制元件朝向PCR芯片保持器偏置的弹性单元。 温度控制元件包括选择性地接触PCR芯片的底表面的顶表面。

    Device and method for detecting biomolecules using adsorptive medium and field effect transistor
    3.
    发明授权
    Device and method for detecting biomolecules using adsorptive medium and field effect transistor 有权
    用吸附介质和场效应晶体管检测生物分子的装置和方法

    公开(公告)号：US08198658B2

    公开(公告)日：2012-06-12

    申请号：US12125506

    申请日：2008-05-22

    申请人： Jeo Young Shim ,  Kyu Tae Yoo ,  Won Seok Chung ,  Jung Im Han

    发明人： Jeo Young Shim ,  Kyu Tae Yoo ,  Won Seok Chung ,  Jung Im Han

    IPC分类号： H01L29/72

    CPC分类号： G01N27/4145

    摘要： A device for detecting biomolecules includes: a semiconductor substrate; a source region and a drain region separately provided at the substrate; a chamber formed at the substrate including a region between the source region and the drain region, the chamber configured to contain a sample including the biomolecules; and an electrode which applies a voltage to the sample in the chamber. The biomolecules are mobile with respect to the electrode and sample. Methods for detecting biomolecules are also disclosed.

    摘要翻译： 用于检测生物分子的装置包括：半导体衬底; 分别设置在所述基板上的源极区域和漏极区域; 在所述基板上形成的室，所述室包括所述源区域和所述漏极区域之间的区域，所述室被配置为容纳包含所述生物分子的样品; 以及向室中的样品施加电压的电极。 生物分子相对于电极和样品是可移动的。 还公开了检测生物分子的方法。

    POLYMERASE CHAIN REACTION APPARATUS
    5.
    发明申请
    POLYMERASE CHAIN REACTION APPARATUS 有权
    聚合物链反应装置

    公开(公告)号：US20120052531A1

    公开(公告)日：2012-03-01

    申请号：US13039630

    申请日：2011-03-03

    申请人： Won-seok CHUNG ,  Kak NAMKOONG ,  Joon-ho KIM

    发明人： Won-seok CHUNG ,  Kak NAMKOONG ,  Joon-ho KIM

    IPC分类号： C12P19/34 ,  C12M1/40

    CPC分类号： B01L9/527 ,  B01L3/502715 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/147 ,  B01L2300/1827

    摘要： A polymerase chain reaction (“PCR”) apparatus includes a PCR chip holder which accommodates and supports a PCR chip, a housing which supports ends of the PCR chip holder, a temperature control element which moves perpendicularly with respect to the PCR chip holder in a space between the housing and the PCR chip holder in the housing, and an elastic unit which elastically biases the temperature control element toward the PCR chip holder, between the temperature control element and the housing. The temperature control element includes a top surface which is selectively contacted to a bottom surface of the PCR chip.

    摘要翻译： 聚合酶链式反应（“PCR”）装置包括：一个PCR芯片保持器，其容纳和支持PCR芯片;支撑PCR芯片保持器端部的壳体;一个相对于PCR芯片保持器垂直移动的温度控制元件 壳体和壳体中的PCR芯片保持器之间的空间以及在温度控制元件和壳体之间弹性地将温度控制元件朝向PCR芯片保持器偏置的弹性单元。 温度控制元件包括选择性地接触PCR芯片的底表面的顶表面。

    Method and a device for detecting genes
    8.
    发明授权
    Method and a device for detecting genes 有权
    方法和检测基因的装置

    公开(公告)号：US08632969B2

    公开(公告)日：2014-01-21

    申请号：US12141448

    申请日：2008-06-18

    申请人： Jeo Young Shim ,  Jung Im Han ,  Won Seok Chung

    发明人： Jeo Young Shim ,  Jung Im Han ,  Won Seok Chung

    IPC分类号： C12Q1/68 ,  C12P19/34 ,  C12M1/34 ,  C12M3/00 ,  H01L21/70 ,  G01N15/06 ,  G01N27/00 ,  C07H21/02 ,  C07H21/04

    CPC分类号： C12Q1/6825 ,  C12Q2539/101 ,  C12Q2531/113 ,  C12Q2527/107

    摘要： A method and a device for detecting nucleic acid are disclosed, wherein impurities in a sample can be easily removed. The method comprises injecting a sample containing an adsorption medium with nucleic adsorbed thereon into a chamber; washing the sample; heating the sample to denature the nucleic acid; cooling down; and detecting nucleic acid by using the biomolecule detection device. The device includes: a source and a drain region; a gate electrode layer; a chamber formed over the semiconductor substrate including the gate electrode layer; and a heating means, wherein a gate adsorption layer to which a nucleic acid is adsorbed is formed on the gate electrode layer. A single-stranded nucleic acid is adsorbed to the gate adsorption layer, and a channel is formed between the source and the drain region. The current in the channel provides a basis to detect a gene.

    摘要翻译： 公开了一种用于检测核酸的方法和装置，其中样品中的杂质可以容易地除去。 该方法包括将含有吸附有核酸的吸附介质的样品注入室中; 洗样 加热样品使核酸变性; 冷却下来; 并通过使用生物分子检测装置检测核酸。 该器件包括：源极和漏极区域; 栅电极层; 形成在包括栅电极层的半导体衬底上的腔室; 以及加热装置，其中在所述栅极电极层上形成有吸附有核酸的栅极吸附层。 单链核酸被吸附到栅极吸附层，并且在源区和漏区之间形成沟道。 通道中的电流为检测基因提供了依据。