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18 条记录 (耗时 0.027 秒)

    Polymerase chain reaction apparatus
    1.
    发明授权
    Polymerase chain reaction apparatus 有权
    聚合酶链反应装置

    公开(公告)号：US08663976B2

    公开(公告)日：2014-03-04

    申请号：US13039630

    申请日：2011-03-03

    申请人： Won-seok Chung ,  Kak Namkoong ,  Joon-ho Kim

    发明人： Won-seok Chung ,  Kak Namkoong ,  Joon-ho Kim

    IPC分类号： C12M1/34 ,  C12M3/00

    CPC分类号： B01L9/527 ,  B01L3/502715 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/147 ,  B01L2300/1827

    摘要： A polymerase chain reaction (“PCR”) apparatus includes a PCR chip holder which accommodates and supports a PCR chip, a housing which supports ends of the PCR chip holder, a temperature control element which moves perpendicularly with respect to the PCR chip holder in a space between the housing and the PCR chip holder in the housing, and an elastic unit which elastically biases the temperature control element toward the PCR chip holder, between the temperature control element and the housing. The temperature control element includes a top surface which is selectively contacted to a bottom surface of the PCR chip.

    摘要翻译： 聚合酶链式反应（“PCR”）装置包括：一个PCR芯片保持器，其容纳和支持PCR芯片;支撑PCR芯片保持器端部的壳体;一个相对于PCR芯片保持器垂直移动的温度控制元件 壳体和壳体中的PCR芯片保持器之间的空间以及在温度控制元件和壳体之间弹性地将温度控制元件朝向PCR芯片保持器偏置的弹性单元。 温度控制元件包括选择性地接触PCR芯片的底表面的顶表面。

    Fluorescence detecting optical system and multi-channel fluorescence detection apparatus including the same
    2.
    发明授权
    Fluorescence detecting optical system and multi-channel fluorescence detection apparatus including the same 有权
    荧光检测光学系统和包括其的多通道荧光检测装置

    公开(公告)号：US09000399B2

    公开(公告)日：2015-04-07

    申请号：US13271101

    申请日：2011-10-11

    申请人： Kyung-ho Kim ,  Joon-ho Kim ,  Kak Namkoong ,  Won-seok Chung

    发明人： Kyung-ho Kim ,  Joon-ho Kim ,  Kak Namkoong ,  Won-seok Chung

    IPC分类号： G01N21/64 ,  G01J3/44 ,  G01J3/02 ,  G01N21/05 ,  G01N21/03

    CPC分类号： G01N21/645 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/4406 ,  G01N21/05 ,  G01N2021/0346 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6478 ,  G01N2201/0635

    摘要： A fluorescence detection optical system detects fluorescence beams with two or more different wavelengths and maintains a focal position through an automatic focusing function. A multi-channel fluorescence detection apparatus includes the fluorescence detection optical system. The fluorescence detection optical system includes an automatic focusing unit which receives light reflected off a microfluidic device and determines a focal point by using an astigmatic method or a knife edge method, and an actuator which adjusts a position of an objective lens according to control of the automatic focusing unit. In addition, the fluorescence detection optical system may include a plurality of dual band pass filters, dichroic devices, etc., which provide light beams emitted from at least two light sources and transfer fluorescence generated from the microfluidic device to a photodetector.

    摘要翻译： 荧光检测光学系统检测具有两个或更多个不同波长的荧光束并通过自动聚焦功能保持焦点位置。 多通道荧光检测装置包括荧光检测光学系统。 荧光检测光学系统包括自动聚焦单元，其接收从微流体装置反射的光并且通过使用散光方法或刀刃方法确定焦点，以及致动器，其根据控制的方式调整物镜的位置 自动对焦单元 此外，荧光检测光学系统可以包括多个双带通滤波器，二向色装置等，其提供从至少两个光源发射的光束并将从微流体装置产生的荧光转移到光电检测器。

    Fluorescence detecting optical system and multi-channel fluorescence detection apparatus having the same
    5.
    发明授权
    Fluorescence detecting optical system and multi-channel fluorescence detection apparatus having the same 有权
    荧光检测光学系统和具有该荧光检测光学系统的多通道荧光检测装置

    公开(公告)号：US08624201B2

    公开(公告)日：2014-01-07

    申请号：US13421119

    申请日：2012-03-15

    申请人： Kyung-ho Kim ,  Joon-ho Kim ,  Kak Namkoong ,  Won-seok Chung

    发明人： Kyung-ho Kim ,  Joon-ho Kim ,  Kak Namkoong ,  Won-seok Chung

    IPC分类号： G01N21/64

    CPC分类号： G01N21/645 ,  G01N21/6445

    摘要： A fluorescence detecting optical system, and a multi-channel fluorescence detection apparatus comprising same, comprising a light source that emits excitation light, a polarizer that transmits light having a predetermined polarization component, a polarizing beam splitter that transmits light having a predetermined polarization component and reflects light having a different polarization component than the predetermined polarization component, and a quarter-wave plate converting linearly polarized to circularly polarized light or vice versa.

    摘要翻译： 一种荧光检测光学系统和包括其的多通道荧光检测装置，包括发射激发光的光源，透射具有预定偏振分量的光的偏振器，透射具有预定偏振分量的光的偏振分束器和 反射具有与预定偏振分量不同的偏振分量的光，以及将线偏振成圆偏振光的四分之一波片反射。

    Microarray reaction device and method of using the same
    8.
    发明授权
    Microarray reaction device and method of using the same 失效
    微阵列反应装置及其使用方法

    公开(公告)号：US08647591B2

    公开(公告)日：2014-02-11

    申请号：US13007750

    申请日：2011-01-17

    申请人： Won-seok Chung ,  Myo-yong Lee ,  Kak Namkoong ,  Woochang Lee

    发明人： Won-seok Chung ,  Myo-yong Lee ,  Kak Namkoong ,  Woochang Lee

    IPC分类号： B01L3/00 ,  B01L99/00 ,  F16K3/00 ,  C40B40/00 ,  C40B60/00 ,  F16K31/00

    CPC分类号： C40B30/00 ,  C40B40/06 ,  C40B40/10 ,  C40B60/12

    摘要： A microarray reaction device includes a fluid container, a reaction chamber, a first channel connected with the fluid container, a second channel connected with the reaction chamber, and a valve. The valve includes a first and second support unit, respectively including a first and second penetration opening unit, extended through a first and second surface thereof. The first and second penetration opening unit is connected to a second end of the first and second channel, respectively. The second support unit includes a third penetration opening unit extended through a second surface thereof. The first and second surfaces contact each other, such that the first support unit and the second support unit are slidably disposed with each other. The microarray reaction device further includes a storing chamber connected with the third penetration opening unit, and a pump connected to the storing chamber and providing pressure to the storing chamber.

    摘要翻译： 微阵列反应装置包括流体容器，反应室，与流体容器连接的第一通道，与反应室连接的第二通道和阀。 阀包括第一和第二支撑单元，分别包括延伸穿过其第一和第二表面的第一和第二穿透开口单元。 第一和第二穿透开口单元分别连接到第一和第二通道的第二端。 第二支撑单元包括延伸穿过其第二表面的第三穿透开口单元。 第一和第二表面彼此接触，使得第一支撑单元和第二支撑单元彼此可滑动地布置。 微阵列反应装置还包括与第三穿透开口单元连接的储存室，以及连接到储存室并向储存室提供压力的泵。

    Method of detecting bio-molecules using field effect transistor without fixing probe bio-molecules on the gate sensing surface
    10.
    发明授权
    Method of detecting bio-molecules using field effect transistor without fixing probe bio-molecules on the gate sensing surface 有权
    使用场效应晶体管检测生物分子的方法，而不将探针生物分子固定在栅极感测表面上

    公开(公告)号：US08038943B2

    公开(公告)日：2011-10-18

    申请号：US11695905

    申请日：2007-04-03

    申请人： Kyu-tae Yoo ,  Kyu-sang Lee ,  Won-seok Chung ,  Jeo-young Shim ,  Yeon-ja Cho

    发明人： Kyu-tae Yoo ,  Kyu-sang Lee ,  Won-seok Chung ,  Jeo-young Shim ,  Yeon-ja Cho

    IPC分类号： G01N27/00

    CPC分类号： G01N33/54373

    摘要： A method of detecting a presence of bio-molecules, or a concentration of the target bio-molecules using a field effect transistor, includes allowing a first sample including a first target bio-molecule to contact a sensing surface of the field effect transistor and measuring a change in an electric signal of the field effect transistor, the field effect transistor including a substrate, a source region and a drain region, the source region and the drain region formed apart from each other on the substrate, the source region and the drain region each doped to having an opposite polarity than a polarity of the substrate, a channel region disposed between the source region and the drain region and an insulating layer including the sensing surface, the insulating layer disposed on the channel region.

    摘要翻译： 使用场效应晶体管检测生物分子的存在或靶生物分子的浓度的方法包括允许包含第一靶生物分子的第一样品接触场效应晶体管的感测表面并测量 场效应晶体管的电信号的变化，所述场效应晶体管包括基板，源极区和漏极区，在所述基板上彼此分离形成的所述源极区和漏极区，所述源极区和漏极 每个被掺杂为具有与衬底的极性相反的极性，设置在源区和漏区之间的沟道区和包括感测表面的绝缘层，绝缘层设置在沟道区上。