摘要:
Disrupting tissue and devices and systems for disrupting tissue. The disclosure describes ways to deliver moieties to a target tissue, where the target tissue in general is not at the point of introduction, in such a way that minimal damage is produced in the tissue at the point of introduction. In some embodiments this is accomplished by jetting fluid at high velocity into the target tissue. The disclosure further describes novel agents deliverable in such systems for use in remodeling tissues. Some of these agents comprise a liquid while others do not. Additionally, although not specifically described in detail much of the disclosure may additionally be used in the delivery of therapeutic drugs.
摘要:
Disrupting tissue and devices and systems for disrupting tissue. The disclosure describes ways to deliver moieties to a target tissue, where the target tissue in general is not at the point of introduction, in such a way that minimal damage is produced in the tissue at the point of introduction. In some embodiments this is accomplished by jetting fluid at high velocity into the target tissue. The disclosure further describes novel agents deliverable in such systems for use in remodeling tissues. Some of these agents comprise a liquid while others do not. Additionally, although not specifically described in detail much of the disclosure may additionally be used in the delivery of therapeutic drugs.
摘要:
An electronic and transducer device can be attached, adhered, or otherwise embedded into or upon a removable oral appliance or other oral device to form a two-way communication assembly. The device contains a motion sensor to detect external forces imposed on the user such as an explosion, for example. The information is stored for medical treatment, among others. In another embodiment, the device provides an electronic and transducer device that can be attached, adhered, or otherwise embedded into or upon a removable oral appliance or other oral device to form a medical tag containing patient identifiable information. Such an oral appliance may be a custom-made device fabricated from a thermal forming process utilizing a replicate model of a dental structure obtained by conventional dental impression methods. The electronic and transducer assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating transducer element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure.
摘要:
Methods and apparatus for transmitting vibrations via an electronic and/or actuator assembly through a custom-fitted dental appliance are disclosed herein. The customized fitting is done by the user. The assembly may be attached, adhered, or otherwise embedded intra-orally on a tooth or oral tissue. The electronic and actuator assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating actuator element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure.
摘要:
A device for delivery of biologic materials, comprising: a cartridge having at least two cylinder bores for fluids to be delivered, wherein each cylinder includes an exit port for a fluid, a plunger within each cylinder for pushing the fluids out of the cylinder, a housing adapted to receive the cartridge, wherein the housing or cartridge includes an adaptor to receive and lock a manifold that operably connects to the exit ports of the cartridge, at least two toothed rams, wherein each toothed ram is at least partially within a cylinder bore, a trigger connected to the housing, wherein the trigger includes a toothed drive rack, a toothed wheel assembly that cooperates with the toothed drive rack and with the toothed rams, as well as methods of making the device, methods of using the device to treat discs, kits including the device.
摘要:
A method and apparatus of treating an abdominal aortic aneurysm in a patient includes the steps of providing a deployable tubular graft of length to extend across the aneurysm. The graft is inserted endovascularly through an artery communicating with the aorta to a site within the aorta whereby an insertion end of the graft is positioned adjacent a non-dilated region of the aorta. The graft is deployed such that the insertion end of the graft is placed against an interior wall of the non-dilated region of the aorta. The graft is held from within the graft against the interior walls of the aorta and while being held, sutures are introduced laparoscopically through a wall of the aorta to the exterior of the graft whereby the graft is sutured to the inner walls of the aorta and the graft.
摘要:
A modular mating stent is adapted to resist migration within a receiving stent. The modular mating stent has a substantially self-expandable first section of predetermined compressibility that is adapted to permit the first section to conform to the shape of a body lumen surrounding the first section. The modular mating stent also has a balloon-expandable second section that is less compressible than the first section, which is adapted to firmly engage a surface of the receiving stent surrounding the second section.
摘要:
An endoluminal prosthesis for treatment of a condition in a lumen in the vicinity of a branch lumen, the lumen being adapted to resist migration, is provided. In one embodiment, the prosthesis includes a substantially tubular main stent adapted for placement in the main lumen. A substantially tubular anchor stent is connected to the main stent and adapted for placement in the branch lumen.
摘要:
A tissue ablation assembly comprises an elongate probe device, at least one ablation electrode element carried by the probe device for conveying ablation energy, and at least one magnetic element for substantially altering the path of the ablation energy conveyed by the electrode element(s). In one embodiment, the magnetic element substantially urges the ablation energy radially outward. In another embodiment, magnetic element takes the form of a ring magnet that exhibits at least four alternating magnetic poles circumferentially disposed around the probe device axis. A method of treating tissue (e.g., a tumor) is also provided. The method comprises introducing a probe device into the patient, conveying ablation energy from the probe device, and applying a magnetic field adjacent the probe device to substantially alter the path of the ablation energy, e.g., by urging the ablation energy conveyed from the probe device radially outward into the tissue to create a tissue lesion, or by urging the ablation energy longitudinally.
摘要:
An ablation device includes an electrode having an enclosed lumen, and a heat sink located within the lumen. An ablation device includes an elongated body, an electrode secured to the elongated body, and a heat sink connected to the electrode, wherein the heat sink is confined by the electrode and at least a portion of the elongated body. An ablation device includes an electrode, and a heat sink connected to the electrode, wherein the heat sink is not connected to a pump.