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公开(公告)号：US20100233048A1
公开(公告)日：2010-09-16
申请号：US12526610
申请日：2008-02-08
CPC分类号： B01D46/546 , B01D46/0027 , B01D46/0036
摘要： A filter media for removing both chemical contaminates and particulate contaminates. The filter media includes a particulate filtration media layer which includes a fine fiber media. The filter media further includes a chemical filtration media layer.
摘要翻译： 用于除去化学污染物和颗粒污染物的过滤介质。 过滤介质包括包含细纤维介质的颗粒过滤介质层。 过滤介质还包括化学过滤介质层。
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公开(公告)号：US20110257032A1
公开(公告)日：2011-10-20
申请号：US13087332
申请日：2011-04-14
申请人： Ram Sasisekharan , Karthik Viswanathan , Udayanath Aich , Rahul Raman , Zachary Shriver , Ido Bachelet
发明人： Ram Sasisekharan , Karthik Viswanathan , Udayanath Aich , Rahul Raman , Zachary Shriver , Ido Bachelet
CPC分类号： G01N33/56983 , C07B2200/11 , C40B40/12 , G01N2333/11 , G01N2400/12 , Y02A50/59
摘要： The present invention provides methods and systems for functionally analyzing glycans and their interaction partners. Among other things, the invention provides modular glycan arrays in which different glycan populations are associated with different discrete solid phase particles. Provided arrays offer many advantages over available systems for assessing glycan binding interactions.
摘要翻译： 本发明提供用于功能分析聚糖及其相互作用配偶体的方法和系统。 除此之外，本发明提供了模块化聚糖阵列，其中不同的聚糖群体与不同的离散固相颗粒相关联。 提供的阵列比用于评估聚糖结合相互作用的可用系统提供了许多优点。
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3.发明申请公开(公告)号：US20100144553A1
公开(公告)日：2010-06-10
申请号：US12623070
申请日：2009-11-20
申请人： Carlos Bosques , Nishla Keiser , Aravind Srinivasan , Rahul Raman , Karthik Viswanathan , Ram Sasisekharan , Pankaj Gandhe , Sasi Raguram
发明人： Carlos Bosques , Nishla Keiser , Aravind Srinivasan , Rahul Raman , Karthik Viswanathan , Ram Sasisekharan , Pankaj Gandhe , Sasi Raguram
IPC分类号： C40B40/12
CPC分类号： G01N33/6851 , G01N33/66 , G01N33/68 , G01N33/6842 , G01N33/6848 , G01N2400/10 , G06F19/703
摘要： The invention relates, in part, to the improved analysis of carbohydrates. In particular, the invention relates to the analysis of carbohydrates, such as N-glycans and O-glycans found on proteins and saccharides attached to lipids. Improved methods, therefore, for the study of glycosylation patterns on cells, tissue and body fluids are also provided. Information from the analysis of glycans, such as the glycosylation patterns on cells, tissues and in body fluids, can be used in diagnostic and treatment methods as well as for facilitating the study of the effects of glycosylation/altered glycosylation. Such methods are also provided. Methods are further provided to assess production processes, to assess the purity of samples containing glycoconjugates, and to select glycoconjugates with the desired glycosylation.
摘要翻译： 本发明部分涉及碳水化合物的改进分析。 特别地，本发明涉及碳水化合物的分析，例如在蛋白质上发现的N-聚糖和O-聚糖以及与脂质连接的糖。 因此，还提供了改进的方法，用于研究细胞，组织和体液上的糖基化模式。 来自聚糖分析的信息，例如细胞，组织和体液中的糖基化模式，可用于诊断和治疗方法以及促进糖基化/改变糖基化作用的研究。 还提供了这样的方法。 进一步提供方法以评估生产过程，以评估含有糖缀合物的样品的纯度，并选择具有所需糖基化的糖缀合物。
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4.发明申请公开(公告)号：US20080241918A1
公开(公告)日：2008-10-02
申请号：US11893171
申请日：2007-08-14
申请人： Ram Sasisekharan , Karthik Viswanathan , Aarthi Chandrasekaran , Rahul Raman , Aravind Srinivasan , S. Raguram , Viswanathan Sasisekharan
发明人： Ram Sasisekharan , Karthik Viswanathan , Aarthi Chandrasekaran , Rahul Raman , Aravind Srinivasan , S. Raguram , Viswanathan Sasisekharan
CPC分类号： G01N33/5308 , G01N2400/10
摘要： The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.
摘要翻译： 本发明提供了一种用于分析聚糖和与其结合的相互作用配偶体之间的相互作用的系统。 本发明还提供结合伞形拓扑聚糖的HA多肽，以及与其相关的试剂和方法。
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公开(公告)号：US10226527B2
公开(公告)日：2019-03-12
申请号：US13253060
申请日：2011-10-04
IPC分类号： A61K39/145 , C12N7/00 , A61K39/12
摘要： The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.
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公开(公告)号：US08915064B2
公开(公告)日：2014-12-23
申请号：US12120689
申请日：2008-05-15
CPC分类号： F01N3/2892 , B01F3/04049 , B01F5/0644 , B01F2005/0017 , F01N3/035 , F01N3/2066 , F01N13/0093 , F01N13/0097 , F01N13/08 , F01N2240/20 , F01N2610/02 , Y02A50/2325 , Y02T10/24
摘要： A flow device for an exhaust treatment system includes a base and at least one flow deflector tube secured to the base. The flow deflector tube includes a flow inlet, a flow outlet, and a passage that extends through the flow deflector tube from the flow inlet to the flow outlet. The flow outlet is at an angled orientation to the flow inlet. A method of mixing reactants and exhaust in an exhaust treatment system includes the steps of injecting reactants into exhaust gases flowing through an exhaust conduit used to convey the exhaust gases from an engine. Bent tubes are disposed in the exhaust conduit and used to mix the exhaust gases and the reactants.
摘要翻译： 用于排气处理系统的流动装置包括底座和固定到底座的至少一个导流管。 导流管包括流入口，流出口和通过导流管从流入口延伸到流出口的通道。 流出口与流入口成倾斜的方向。 在排气处理系统中混合反应物和废气的方法包括将反应物注入流过用于输送来自发动机的废气的排气导管的废气中的步骤。 弯管设置在排气管道中并用于混合排气和反应物。
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7.发明授权Influenza treatment and/or characterization, human-adapted HA polypeptides; vaccines 有权流感治疗和/或表征，人类适应的HA多肽; 疫苗公开(公告)号：US08802110B2
公开(公告)日：2014-08-12
申请号：US13239376
申请日：2011-09-21
IPC分类号： A61K39/145 , A61K39/12
CPC分类号： C07K14/005 , A61K39/12 , A61K39/145 , C07K16/1018 , C12N7/00 , C12N2760/16122 , C12N2760/16133 , C12N2760/16134 , G01N33/56983 , G01N2333/11
摘要： The present invention provides, among other things, methods, reagents, and systems for the treatment, detection, analysis, and/or characterization of influenza infections.
摘要翻译： 本发明尤其提供用于治疗，检测，分析和/或表征流感感染的方法，试剂和系统。
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公开(公告)号：US20130134110A1
公开(公告)日：2013-05-30
申请号：US13481429
申请日：2012-05-25
申请人： Karthik Viswanathan , Philip Edward Johnson , Dustin Zastera , James Doyle , Gregory L. LaVallee
发明人： Karthik Viswanathan , Philip Edward Johnson , Dustin Zastera , James Doyle , Gregory L. LaVallee
IPC分类号： B01D29/56
CPC分类号： B01D29/56 , B01D29/606 , B01D35/143 , C07C7/12 , C07C7/13
摘要： Described herein are filter assemblies for removing high molecular weight organic components from liquefied petroleum gas, as well as methods for removing high molecular weight components from liquefied petroleum gases. The filter assemblies include an upstream carbon-containing filter media pack and a downstream filter media pack.
摘要翻译： 本文描述了用于从液化石油气中除去高分子量有机组分的过滤器组件以及从液化石油气中除去高分子量组分的方法。 过滤器组件包括上游含碳过滤介质包和下游过滤介质包。
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9.发明申请HEMAGGLUTININ POLYPEPTIDES, AND REAGENTS AND METHODS RELATING THERETO 审中-公开HEMAGGLUTININ POLYPEPTIDES，以及与其相关的试剂和方法公开(公告)号：US20120213819A1
公开(公告)日：2012-08-23
申请号：US13253060
申请日：2011-10-04
CPC分类号： A61K39/145 , A61K39/12 , C12N7/00 , C12N2760/16134
摘要： The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.
摘要翻译： 本发明提供了一种用于分析聚糖和与其结合的相互作用配偶体之间的相互作用的系统。 本发明还提供结合伞形拓扑聚糖的HA多肽，以及与其相关的试剂和方法。
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10.发明申请公开(公告)号：US20060127950A1
公开(公告)日：2006-06-15
申请号：US11244826
申请日：2005-10-06
申请人： Carlos Bosques , Nishla Keiser , Aravind Srinivasan , Rahul Raman , Karthik Viswanathan , Ram Sasisekharan , Pankaj Gandhe , Sasi Raguram
发明人： Carlos Bosques , Nishla Keiser , Aravind Srinivasan , Rahul Raman , Karthik Viswanathan , Ram Sasisekharan , Pankaj Gandhe , Sasi Raguram
CPC分类号： G01N33/6851 , G01N33/66 , G01N33/68 , G01N33/6842 , G01N33/6848 , G01N2400/10 , G16C20/20
摘要： The invention relates, in part, to the improved analysis of carbohydrates. In particular, the invention relates to the analysis of carbohydrates, such as N-glycans and O-glycans found on proteins and saccharides attached to lipids. Improved methods, therefore, for the study of glycosylation patterns on cells, tissue and body fluids are also provided. Information from the analysis of glycans, such as the glycosylation patterns on cells, tissues and in body fluids, can be used in diagnostic and treatment methods as well as for facilitating the study of the effects of glycosylation/altered glycosylation. Such methods are also provided. Methods are further provided to assess production processes, to assess the purity of samples containing glycoconjugates, and to select glycoconjugates with the desired glycosylation.
摘要翻译： 本发明部分涉及碳水化合物的改进分析。 特别地，本发明涉及碳水化合物的分析，例如在蛋白质上发现的N-聚糖和O-聚糖以及与脂质连接的糖。 因此，还提供了改进的方法，用于研究细胞，组织和体液上的糖基化模式。 来自聚糖分析的信息，例如细胞，组织和体液中的糖基化模式，可用于诊断和治疗方法以及促进糖基化/改变糖基化作用的研究。 还提供了这样的方法。 进一步提供方法以评估生产过程，以评估含有糖缀合物的样品的纯度，并选择具有所需糖基化的糖缀合物。
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