公开(公告)号：US20110196454A1

公开(公告)日：2011-08-11

申请号：US12665695

申请日：2009-11-13

申请人： Angela Strand ,  Mark Zdeblick ,  George Savage ,  David O'reilly

发明人： Angela Strand ,  Mark Zdeblick ,  George Savage ,  David O'reilly

IPC分类号： A61N1/36

CPC分类号： A61N1/36071 ,  A61N1/05 ,  A61N1/36132 ,  A61N1/36135 ,  G06F19/3418 ,  G06F19/3481

摘要： Sensing system, device, and method for therapy modulation are provided. Various aspects include a receive module and a therapy-related action module. The receive module may receive a therapy parameter of an individual. The therapy-related action module may effectuate, based on the therapy parameter, a therapy-related action associated with a nervous system of the individual.

摘要翻译： 提供了用于治疗调制的感测系统，装置和方法。 各方面包括接收模块和治疗相关动作模块。 接收模块可以接收个体的治疗参数。 治疗相关动作模块可以基于治疗参数来实现与个体的神经系统相关联的治疗相关动作。

公开(公告)号：US20120016211A1

公开(公告)日：2012-01-19

申请号：US13243759

申请日：2011-09-23

申请人： George Savage ,  Hooman Hafezi ,  Olivier Colliou ,  Mark Zdeblick ,  Angela Strand

发明人： George Savage ,  Hooman Hafezi ,  Olivier Colliou ,  Mark Zdeblick ,  Angela Strand

IPC分类号： A61B5/07

CPC分类号： A61B5/053 ,  A61B5/04884 ,  A61B5/073 ,  A61B5/1107 ,  A61B5/14539 ,  A61B5/42 ,  A61B5/6861 ,  A61B2560/0214 ,  A61B2560/0242 ,  G06F19/00

摘要： Portable electroviscerography systems are provided. Aspects of the systems include a body-associated receiver and an ingestible identifier unit, both of which are configured to detect visceral electrical signals. The system communicates with an extra-corporeal data processor configured to receive data from the body-associated receiver and generate and electroviscerogram from the received data. Also provided are methods of producing electroviscerograms using systems of the present invention.

摘要翻译： 提供便携式电视摄影系统。 系统的方面包括身体相关联的接收器和可摄取的识别器单元，它们都配置成检测内脏电信号。 该系统与配置成从身体相关联的接收器接收数据并从接收到的数据生成电视图的外部数据处理器进行通信。 还提供了使用本发明的系统生产电视图的方法。

公开(公告)号：US08583227B2

公开(公告)日：2013-11-12

申请号：US13243759

申请日：2011-09-23

申请人： George Savage ,  Hooman Hafezi ,  Olivier Colliou ,  Mark Zdeblick ,  Angela Strand

发明人： George Savage ,  Hooman Hafezi ,  Olivier Colliou ,  Mark Zdeblick ,  Angela Strand

IPC分类号： A61B5/05

CPC分类号： A61B5/053 ,  A61B5/04884 ,  A61B5/073 ,  A61B5/1107 ,  A61B5/14539 ,  A61B5/42 ,  A61B5/6861 ,  A61B2560/0214 ,  A61B2560/0242 ,  G06F19/00

摘要： Portable electroviscerography systems are provided. Aspects of the systems include a body-associated receiver and an ingestible identifier unit, both of which are configured to detect visceral electrical signals. The system communicates with an extra-corporeal data processor configured to receive data from the body-associated receiver and generate and electroviscerogram from the received data. Also provided are methods of producing electroviscerograms using systems of the present invention.

摘要翻译： 提供便携式电视摄影系统。 系统的方面包括身体相关联的接收器和可摄取的识别器单元，它们都配置成检测内脏电信号。 该系统与配置成从身体相关联的接收器接收数据并从接收到的数据生成电视图的外部数据处理器进行通信。 还提供了使用本发明的系统生产电视图的方法。

公开(公告)号：US20130172690A1

公开(公告)日：2013-07-04

申请号：US13640699

申请日：2011-04-11

申请人： Lawrence Arne ,  Benedict Costello ,  Yuriy Mestman ,  Timothy Robertson ,  George Savage ,  Angela Strand ,  Todd Thompson ,  Mark Zdeblick ,  William McAllister

发明人： Lawrence Arne ,  Benedict Costello ,  Yuriy Mestman ,  Timothy Robertson ,  George Savage ,  Angela Strand ,  Todd Thompson ,  Mark Zdeblick ,  William McAllister

IPC分类号： A61B5/00 ,  A61B5/053

CPC分类号： A61B5/4833 ,  A61B5/053 ,  A61B5/6846 ,  A61B2562/0214 ,  A61M15/0016 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0083 ,  A61M15/009 ,  A61M2016/0024 ,  A61M2016/0039 ,  A61M2205/13 ,  A61M2205/331 ,  A61M2205/3317 ,  A61M2205/332 ,  A61M2205/3375 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/6009 ,  A61M2205/6054 ,  A61M2230/63 ,  A61M2230/65

摘要： An apparatus is disclosed as part of a system for tracking and confirming delivery of a medicinal dose to a user. The apparatus includes a detector. The detector is secured to and communicatively coupled to the user and is capable of detecting a current flow through the user's body. The current flow is produced when the user makes contact with the apparatus. The apparatus includes at least two contact areas connected to a power source where a circuit and, hence, a current path is completed through the user's body as the user makes contact with the apparatus. The current flow is detected by the detector, which is coupled to the user. Also disclosed is an apparatus for tracking and confirming delivery of a medicinal dose to a user where the apparatus includes an acoustic detector. Upon loading the dose into a chamber an acoustic vibration is generated. The vibration is detected and correlated with a current flow that is produced when the user makes contact with the apparatus. The combined event of vibration detection and current flow detection confirms that the dose is loaded and the user is in contact with the apparatus and ready to receive the dose.

摘要翻译： 公开了一种用于跟踪并确认向用户传送药用剂量的系统的一部分的装置。 该装置包括检测器。 检测器被固定到并且通信地耦合到用户，并且能够检测通过用户身体的电流。 当用户与设备接触时产生电流。 该设备包括连接到电源的至少两个接触区域，其中当用户与设备接触时，电路和因此的电流路径通过用户的身体完成。 电流由检测器检测到，该检测器耦合到用户。 还公开了一种用于跟踪并确认药物剂量递送给用户的装置，其中该装置包括声学检测器。 当将剂量加载到室中时，产生声振动。 检测振动并与用户与设备接触时产生的电流相关联。 振动检测和电流检测的组合事件证实了剂量被加载并且使用者与设备接触并准备接收剂量。

公开(公告)号：US08055334B2

公开(公告)日：2011-11-08

申请号：US12665022

申请日：2009-12-10

申请人： George Savage ,  Hooman Hafezi ,  Olivier Colliou ,  Mark Zdeblick ,  Angela Strand

发明人： George Savage ,  Hooman Hafezi ,  Olivier Colliou ,  Mark Zdeblick ,  Angela Strand

IPC分类号： A61B5/04

CPC分类号： A61B5/053 ,  A61B5/04884 ,  A61B5/073 ,  A61B5/1107 ,  A61B5/14539 ,  A61B5/42 ,  A61B5/6861 ,  A61B2560/0214 ,  A61B2560/0242 ,  G06F19/00

摘要： Portable electroviscerography systems are provided. Aspects of the systems include a body-associated receiver and an ingestible identifier unit, both of which are configured to detect visceral electrical signals. The system communicates with an extra-corporeal data processor configured to receive data from the body-associated receiver and generate and electroviscerogram from the received data. Also provided are methods of producing electroviscerograms using systems of the present invention.

摘要翻译： 提供便携式电视摄影系统。 系统的方面包括身体相关联的接收器和可摄取的识别器单元，它们都配置成检测内脏电信号。 该系统与配置成从身体相关联的接收器接收数据并从接收到的数据生成电视图的外部数据处理器进行通信。 还提供了使用本发明的系统生产电视图的方法。

公开(公告)号：US20110040203A1

公开(公告)日：2011-02-17

申请号：US12665022

申请日：2009-12-10

申请人： George Savage ,  Hooman Hafezi ,  Olivier Colliou ,  Mark Zdeblick ,  Angela Strand

发明人： George Savage ,  Hooman Hafezi ,  Olivier Colliou ,  Mark Zdeblick ,  Angela Strand

IPC分类号： A61B5/0488

CPC分类号： A61B5/053 ,  A61B5/04884 ,  A61B5/073 ,  A61B5/1107 ,  A61B5/14539 ,  A61B5/42 ,  A61B5/6861 ,  A61B2560/0214 ,  A61B2560/0242 ,  G06F19/00

摘要： Portable electroviscerography systems are provided. Aspects of the systems include a body-associated receiver and an ingestible identifier unit, both of which are configured to detect visceral electrical signals. The system communicates with an extra-corporeal data processor configured to receive data from the body-associated receiver and generate and electroviscerogram from the received data. Also provided are methods of producing electroviscerograms using systems of the present invention.

摘要翻译： 提供便携式电视摄影系统。 系统的方面包括身体相关联的接收器和可摄取的识别器单元，它们都配置成检测内脏电信号。 该系统与配置成从身体相关联的接收器接收数据并从接收到的数据生成电视图的外部数据处理器进行通信。 还提供了使用本发明的系统生产电视图的方法。

公开(公告)号：US20130096501A1

公开(公告)日：2013-04-18

申请号：US13805987

申请日：2011-06-20

申请人： Lawrence Arne ,  Todd Thompson ,  Mark Zdeblick ,  Angela Strand ,  George Savage ,  Yuriy Mestman ,  William H. McAllister

发明人： Lawrence Arne ,  Todd Thompson ,  Mark Zdeblick ,  Angela Strand ,  George Savage ,  Yuriy Mestman ,  William H. McAllister

IPC分类号： A61M5/50

CPC分类号： A61M5/5086 ,  A61M15/0016 ,  A61M15/009 ,  A61M2016/0024 ,  A61M2016/0039 ,  A61M2205/13 ,  A61M2205/331 ,  A61M2205/3317 ,  A61M2205/332 ,  A61M2205/3375 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/6009 ,  A61M2205/6054 ,  A61M2230/63 ,  A61M2230/65 ,  A61N5/0624

摘要： A method is disclosed for detecting, by a sensing and data acquisition circuit module, at least one parameter associated with an access port. The method includes wiping at least a portion of an access port, allowing the access port to dry for a predetermined amount of time, accessing the access port with an access device, such as a syringe, and detecting at least one parameter associated with the access port by the sensor and acquisition module. An access port is disclosed that includes a sensor and a data acquisition module for sensing, recording, and providing an alert associated with the detection of the at least one parameter associated with the access port.

摘要翻译： 公开了一种用于通过感测和数据采集电路模块检测与接入端口相关联的至少一个参数的方法。 该方法包括擦除访问端口的至少一部分，允许访问端口干预预定的时间量，使用诸如注射器的访问设备访问访问端口，以及检测与访问相关联的至少一个参数 端口由传感器和采集模块组成。 公开了一种访问端口，其包括传感器和数据获取模块，用于感测，记录和提供与检测与接入端口相关联的至少一个参数相关联的警报。

公开(公告)号：US08858432B2

公开(公告)日：2014-10-14

申请号：US12524837

申请日：2008-02-01

申请人： Timothy Robertson ,  George Savage ,  Mark Zdeblick ,  Yashar Behzadi ,  Benedict Costello ,  Jeremy Frank ,  Hooman Hafezi ,  Tariq Haniff ,  David O'Reilly

发明人： Timothy Robertson ,  George Savage ,  Mark Zdeblick ,  Yashar Behzadi ,  Benedict Costello ,  Jeremy Frank ,  Hooman Hafezi ,  Tariq Haniff ,  David O'Reilly

IPC分类号： A61B1/00 ,  H04B5/00 ,  H01M6/00 ,  H01Q1/27 ,  A61B5/07 ,  A61B5/00 ,  A61J3/00 ,  H01Q1/00 ,  A61B5/0205

CPC分类号： A61B5/073 ,  A61B5/0028 ,  A61B5/0031 ,  A61B5/0073 ,  A61B5/0205 ,  A61B5/14507 ,  A61B5/6846 ,  A61B5/6861 ,  A61B5/6873 ,  A61B2560/0214 ,  A61J3/007 ,  G01N27/3277 ,  H01M6/005 ,  H01Q1/273 ,  H04B5/0068 ,  Y10S128/903

摘要： Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.

摘要翻译： 提供了包含可摄入事件标记（即IEM）和个人信号接收器的可摄入事件标记系统。 IEM的实施方案包括标识符，其可以或可以不存在于生理上可接受的载体中。 标识符的特征在于与身体的目标内部生理部位（例如消化道内部靶位点）接触时被激活。 个人信号接收器被配置为与身体内部或身体上的生理位置相关联并且接收IEM的信号。 在使用期间，IEM广播由个人信号接收机接收的信号。

公开(公告)号：US20100185055A1

公开(公告)日：2010-07-22

申请号：US12524837

申请日：2008-02-01

申请人： Timothy Robertson ,  George Savage ,  Mark Zdeblick ,  Yashar Behzadi ,  Benedict Costello ,  Jeremy Frank ,  Hooman Hafezi ,  Tariq Haniff ,  David O'Reilly

发明人： Timothy Robertson ,  George Savage ,  Mark Zdeblick ,  Yashar Behzadi ,  Benedict Costello ,  Jeremy Frank ,  Hooman Hafezi ,  Tariq Haniff ,  David O'Reilly

IPC分类号： A61B1/00

CPC分类号： A61B5/073 ,  A61B5/0028 ,  A61B5/0031 ,  A61B5/0073 ,  A61B5/0205 ,  A61B5/14507 ,  A61B5/6846 ,  A61B5/6861 ,  A61B5/6873 ,  A61B2560/0214 ,  A61J3/007 ,  G01N27/3277 ,  H01M6/005 ,  H01Q1/273 ,  H04B5/0068 ,  Y10S128/903

摘要： Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.

摘要翻译： 提供了包含可摄入事件标记（即IEM）和个人信号接收器的可摄入事件标记系统。 IEM的实施方案包括标识符，其可以或可以不存在于生理上可接受的载体中。 标识符的特征在于与身体的目标内部生理部位（例如消化道内部靶位点）接触时被激活。 个人信号接收器被配置为与身体内部或身体上的生理位置相关联并且接收IEM的信号。 在使用期间，IEM广播由个人信号接收机接收的信号。

公开(公告)号：US08036748B2

公开(公告)日：2011-10-11

申请号：US12665111

申请日：2009-11-13

申请人： Mark Zdeblick ,  Marc Jensen ,  Olivier Colliou ,  Angela Strand

发明人： Mark Zdeblick ,  Marc Jensen ,  Olivier Colliou ,  Angela Strand

IPC分类号： A61N1/00 ,  A61K9/22

CPC分类号： A61N1/37217 ,  A61B5/073 ,  A61J3/06 ,  A61J3/07 ,  A61M5/1723 ,  A61M31/002 ,  G06F19/00

摘要： An ingestible therapy activator system and method are provided. In one aspect, the ingestible therapy activator includes an ingestible device having an effector module to send an effector instruction and a responder module associated with a therapeutic device. The responder module may receive and process the effector instruction, resulting in a response by the therapeutic device. Examples of responses by therapeutic device include activating a therapy, deactivating a therapy, modulating a therapy, and discontinuing a therapy.

摘要翻译： 提供了一种可摄取的治疗激活剂系统和方法。 在一个方面，可摄入治疗激活剂包括具有效应器模块的可摄取装置，以发送效应器指令和与治疗装置相关联的应答模块。 应答器模块可以接收并处理效应器指令，导致治疗装置的响应。 治疗装置的反应的实例包括激活治疗，停用治疗，调节治疗和停止治疗。