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    Fuzzy logic
    1.
    发明授权
    Fuzzy logic 有权
    模糊逻辑

    公开(公告)号：US09486568B2

    公开(公告)日：2016-11-08

    申请号：US14190782

    申请日：2014-02-26

    申请人： B. BRAUN AVITUM AG

    发明人： Richard Atallah ,  Christof Strohhoefer ,  Juergen Wagner

    IPC分类号： A61M1/16 ,  A61M1/34 ,  B01D61/22 ,  B01D61/32 ,  A61B5/02 ,  A61B5/021 ,  A61M1/36 ,  A61B5/024 ,  A61B5/145 ,  A61B5/1455

    CPC分类号： A61M1/3403 ,  A61B5/02 ,  A61B5/021 ,  A61B5/024 ,  A61B5/14535 ,  A61B5/14551 ,  A61M1/16 ,  A61M1/1613 ,  A61M1/3609 ,  A61M1/3639 ,  A61M2205/3303 ,  A61M2205/3341 ,  A61M2205/3344 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/005 ,  A61M2230/207 ,  A61M2230/30 ,  B01D61/22 ,  B01D61/32

    摘要： The described system and method for blood treatment are configured to detect at least two hemodynamic parameters, for example the blood pressure and the relative blood volume, during the blood treatment. At least two fuzzy modules receive measuring values of the hemodynamic parameters as input variables, wherein the output signals transmitted by the fuzzy modules are weighted by at least one weighting module. A setting means effectuates setting of at least one variable, for example an ultrafiltration rate, a dialysis fluid conductivity or a dialysis fluid temperature, in response to the output signal transmitted by the weighting module. In this way, e.g. threatening intradialytic hypotensive episodes can be detected and avoided. The system can be designed as a dialyzer for hemodialysis, hemofiltration or hemodiafiltration.

    摘要翻译： 所描述的用于血液处理的系统和方法被配置为在血液处理期间检测至少两个血液动力学参数，例如血压和相对血液体积。 至少两个模糊模块接收作为输入变量的血液动力学参数的测量值，其中由模糊模块发送的输出信号由至少一个加权模块加权。 响应于由加权模块发送的输出信号，设定装置实现至少一个变量的设置，例如超滤速率，透析流体导电率或透析液体温度。 以这种方式，例如 可以检测和避免威胁性内分泌性低血压事件。 该系统可以设计为用于血液透析，血液滤过或血液透析过滤的透析器。

    Device and method for identifying a malfunction in an extracorporeal blood circulation
    3.
    发明授权
    Device and method for identifying a malfunction in an extracorporeal blood circulation 有权

    公开(公告)号：US10099000B2

    公开(公告)日：2018-10-16

    申请号：US14633663

    申请日：2015-02-27

    申请人： B. BRAUN AVITUM AG

    发明人： Christof Strohhoefer ,  Jens Schreiber ,  Jennifer Steger

    IPC分类号： A61M1/36 ,  G01L11/00 ,  A61M1/14 ,  A61M1/34 ,  G01F1/00 ,  A61M39/10

    摘要： Methods and systems for identifying a malfunction in the extracorporeal blood circulation of a dialysis machine are disclosed. The malfunction may be identified by detecting at least one state parameter; determining a first evaluation criterion for identifying a malfunction in the extracorporeal blood circulation (FEB); using the first evaluation criterion, making a decision with respect to the presence of a malfunction in the extracorporeal blood circulation, generating a first error signal, and monitoring the detected state parameter; determining at least one further evaluation criterion; using the at least one further evaluation criterion, making a decision with respect to the presence of a malfunction in the extracorporeal blood circulation and generating at least one further error signal; combining the first error signal and the at least one further error signal to result in a combined error signal; and triggering an alarm if the combined error signal exceeds a predetermined limit value.

    System for identifying a dialyzer apparatus or a component thereof, and sensor device which can be used for this purpose
    5.
    发明授权
    System for identifying a dialyzer apparatus or a component thereof, and sensor device which can be used for this purpose 有权

    公开(公告)号：US10357599B2

    公开(公告)日：2019-07-23

    申请号：US14780195

    申请日：2014-03-27

    申请人： B. BRAUN AVITUM AG

    发明人： Christof Strohhoefer ,  Silvie Krause

    IPC分类号： A61M1/16 ,  A61M1/34 ,  A61M1/36 ,  A61B5/1455

    摘要： A system for acquiring or measuring information relating to a state of dialysance, identifying a dialyzer apparatus, or identifying a membrane filter device during the operation of the dialyzer apparatus in a dialysis treatment of a patient. The dialyzer apparatus includes a housing having an internal volume portion and a membrane filter device arranged within the internal volume portion. The housing allows transmission of radiation. A sensor device connected to the housing of the dialyzer apparatus includes a signal receiving device designed to receive a radiation signal from the housing, the signal characteristic of the state or the identification of the dialyzer apparatus or of the membrane filter unit of the dialyzer apparatus.

    Apparatus and method for determining distribution volume in dialysis patient
    6.
    发明授权
    Apparatus and method for determining distribution volume in dialysis patient 有权

    公开(公告)号：US10101316B2

    公开(公告)日：2018-10-16

    申请号：US14667124

    申请日：2015-03-24

    申请人： B. BRAUN AVITUM AG

    发明人： Henrik Wolff ,  Joern Meibaum ,  Christof Strohhoefer

    IPC分类号： A61M37/00 ,  G01N33/487 ,  G01F1/00 ,  A61M1/16

    摘要： Apparatus and control methods for determining a distribution volume of at least one uremic substance in a dialysis patient are disclosed. The apparatus may include a dialyzer, an optional flow rate measuring system for detecting the flow rate of a dialysis fluid through the dialyzer, a dialysis fluid measuring system for detecting at least one dialysis fluid parameter that depends on the at least one substance in the dialysis fluid, and a computer for establishing a dialysis dose based on the dialysis fluid parameter and for establishing the distribution volume based on the dialysis dose taking a clearance factor and dialysis duration into account.

    APPARATUS AND APPARATUS CONTROL METHOD FOR THE QUANTITATIVE CONCENTRATION DETERMINATION OF SELECTED SUBSTANCES FILTERED OUT OF A PATIENT'S BODY IN A FLUID
    8.
    发明申请
    APPARATUS AND APPARATUS CONTROL METHOD FOR THE QUANTITATIVE CONCENTRATION DETERMINATION OF SELECTED SUBSTANCES FILTERED OUT OF A PATIENT'S BODY IN A FLUID 有权
    用于定量浓度测定流体中患者身体的筛选物质的装置和装置控制方法

    公开(公告)号：US20150323447A1

    公开(公告)日：2015-11-12

    申请号：US14691208

    申请日：2015-04-20

    申请人： B. BRAUN AVITUM AG

    发明人： Miran Alic ,  Christof Strohhoefer ,  Waldemar Janik

    IPC分类号： G01N21/25 ,  G01N21/31

    CPC分类号： G01N21/255 ,  A61M1/1617 ,  A61M2205/3313 ,  G01N21/3103 ,  G01N21/33 ,  G01N21/85 ,  G01N2201/061 ,  G01N2800/347

    摘要： Methods and apparatus are disclosed for determining a substance in a fluid excreted/extracted from the body or spent dialysate, e.g., for determining a quality measure for the dialysis, such as the concentration of selected toxic substances, and/or for determining a removed total quantity of uremic toxins during a dialysis with a dialysis apparatus. A concentration of a substance in the fluid may be determined by: detecting, by an absorption sensor, a first extinction signal of the fluid at an analysis wavelength at a defined first pH value of the fluid; adjusting, by a pH adjusting device, a second pH value of the fluid which differs from the first pH value; detecting, by the absorption sensor, a second extinction signal of the fluid at the analysis wavelength at the second pH value; and processing/comparing the two extinction signals for the first and the second pH values and determining an absolute concentration of the substance dissolved in the fluid.

    摘要翻译： 公开了用于确定从身体排出/提取的流体中的物质或废透析液的方法和装置，例如用于确定透析的质量测量，例如所选择的有毒物质的浓度和/或用于确定去除的总量 用透析仪透析期间尿毒症毒素的量。 流体中物质的浓度可以通过以下方式确定：通过吸收传感器在流体的确定的第一pH值下以分析波长检测流体的第一消光信号; 通过pH调节装置调节与第一pH值不同的流体的第二pH值; 通过吸收传感器检测处于第二pH值的分析波长处的流体的第二消光信号; 以及处理/比较第一和第二pH值的两个消光信号，并确定溶解在流体中的物质的绝对浓度。