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公开(公告)号：US09463064B2
公开(公告)日：2016-10-11
申请号：US14846814
申请日：2015-09-06
Applicant: Boston Scientific Scimed Inc.
Inventor： Raj Subramaniam , Josef V. Koblish , Zaya Tun , Guy R. Harvey , Minhchau N. Cao , Kurt D. Sparks
CPC classification number: A61B18/1492 , A61B2018/00023 , A61B2018/00065 , A61B2018/0022 , A61B2018/00232 , A61B2018/00238 , A61B2018/00345 , A61B2018/00351 , A61B2018/00577 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00839 , A61B2018/1472
Abstract: Devices, systems, and methods for performing ablation therapy on body tissue are disclosed. An example ablation device for treating body tissue includes an ionically conductive balloon and a radio-frequency electrode that delivers RF energy into a distal section of the balloon. The balloon is configured to transmit the RF energy in a direction distally towards a leading end of the ablation device. Multiple ablation electrodes on the device can be used for providing lesions of different size or shape.
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公开(公告)号：US10813687B2
公开(公告)日：2020-10-27
申请号：US14704392
申请日：2015-05-05
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： Josef V. Koblish , Leslie Oley
Abstract: Discloses herein are ablative catheters and methods of use. The catheters can include a cooling chamber for circulating cooling fluid within the catheter tip to reduce hot spots within the catheter tip and/or to reduce the formation of coagulum. A proximal cooling chamber can be positioned proximally to a thermal mass for cooling a proximal portion of the catheter. In addition, or alternatively, a distal cooling chamber can be positioned for cooling a distal portion of the catheter tip. The cooling fluid can flow the ablative catheter in an open, closed, or open and closed loop.
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3.发明授权公开(公告)号：US10070910B2
公开(公告)日：2018-09-11
申请号：US13938086
申请日：2013-07-09
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： Frank W. Ingle , Robert F. Bencini , Josef V. Koblish , Jonathan A. Wohlgemuth , Paul A. Roche
CPC classification number: A61B18/02 , A61B2017/22051 , A61B2017/22054 , A61B2018/00196 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61M25/1011
Abstract: Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.
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4.发明授权Systems and methods for making and using medical ablation systems having mapping catheters with improved anchoring ability 有权用于制造和使用具有改进的锚定能力的具有映射导管的医疗消融系统的系统和方法公开(公告)号：US09480521B2
公开(公告)日：2016-11-01
申请号：US14282726
申请日：2014-05-20
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： Isaac Kim , Josef V. Koblish , David McGee
CPC classification number: A61B18/02 , A61B5/0422 , A61B5/0538 , A61B5/4836 , A61B5/6853 , A61B5/6856 , A61B5/6857 , A61B18/1492 , A61B18/18 , A61B2017/00053 , A61B2017/00867 , A61B2018/00166 , A61B2018/0022 , A61B2018/00375 , A61B2018/00577 , A61B2018/00642 , A61B2018/00916 , A61B2018/0212 , A61B2018/1407
Abstract: A mapping catheter includes an elongated body for inserting into patient vasculature. A distal end of the elongated body includes a distal portion that includes a plurality of electrodes, a proximal portion disposed proximal to the distal portion, and a reduced-dimension portion disposed between the proximal and distal portions. The distal end is formed, at least in part, from a memory shape material that bends into a preformed shape upon release from a confined space. The preformed shape includes a first loop formed, at least in part, by the distal portion. The first loop is transverse to a longitudinal axis of the proximal portion. The reduced-dimension portion is configured and arranged to bend such that the reduced-dimension section advances distally through the first loop when the first loop is held in a fixed position and a force is applied distally along the longitudinal axis of the proximal portion.
Abstract translation: 映射导管包括用于插入患者脉管系统的细长体。 细长主体的远端包括远端部分，其包括多个电极，靠近远端部分设置的近端部分和设置在近端部分和远端部分之间的缩小部分。 远端至少部分地由从密闭空间释放时弯曲成预成形的记忆形状材料形成。 预成型形状包括至少部分由远端部分形成的第一环。 第一回路横向于近端部分的纵向轴线。 减小尺寸部分被构造和布置成弯曲，使得当第一环保持在固定位置并且沿着近端部分的纵向轴线向远侧施加力时，缩小尺寸部分向远侧延伸穿过第一环。
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公开(公告)号：US09393072B2
公开(公告)日：2016-07-19
申请号：US14295089
申请日：2014-06-03
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： Isaac J. Kim , Josef V. Koblish , Simplicio A. Velilla , Mark D. Mirigian
CPC classification number: A61B18/18 , A61B5/0422 , A61B5/7217 , A61B18/1492 , A61B2017/00044 , A61B2017/00084 , A61B2018/00029 , A61B2018/00351 , A61B2018/00577 , A61B2018/00589 , A61B2018/00773 , A61B2018/00839 , A61B2018/1467 , A61B2218/002 , Y10T29/49002 , Y10T29/49826
Abstract: An embodiment of an open-irrigated catheter system comprises a tip section, a distal insert, and mapping electrodes. The tip section has an exterior wall that defines an open interior region within the tip section. The exterior wall includes mapping electrode openings and irrigation ports. The exterior wall is conductive for delivering radio frequency (RF) energy for an RF ablation procedure. The irrigation ports are in fluid communication with the open interior region to allow fluid to flow from the open interior region through the irrigation ports. The distal insert is positioned within the tip section to separate the open region into a distal fluid reservoir and a proximal fluid reservoir. The mapping electrodes are positioned in the mapping electrode openings in the tip section.
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Patent Agency Ranking
公开(公告)号：US09241761B2
公开(公告)日：2016-01-26
申请号：US13729685
申请日：2012-12-28
Applicant: Boston Scientific Scimed, Inc. , Koninklijke Philips N.V.
Inventor： Darrell L. Rankin , Josef V. Koblish , Szabolcs Deladi
IPC: A61B8/00 , A61B18/14 , A61B8/12 , A61M5/00 , A61B8/08 , A61B18/12 , A61B19/00 , A61B17/00 , A61B18/00
CPC classification number: A61B18/1492 , A61B8/12 , A61B8/445 , A61B8/4477 , A61B8/5207 , A61B8/54 , A61B18/1206 , A61B2017/00106 , A61B2017/003 , A61B2018/00023 , A61B2018/00577 , A61B2018/00821 , A61B2018/00982 , A61B2090/3784 , A61B2090/3966 , A61B2217/007 , A61M5/00
Abstract: Devices and systems for ultrasonically imaging anatomical structures and performing ablation therapy within the body are disclosed. A combined ablation and ultrasound imaging probe includes an ablation electrode tip including an ablation electrode configured for delivering ablation energy, and a number of ultrasonic imaging sensors configured for imaging the tissue surrounding the probe. The ultrasonic imaging sensors are supported within the interior of the tip via a tip insert, and deliver ultrasonic waves through acoustic openings formed through the tip. The tip insert separates an interior lumen within the tip into a proximal fluid chamber and a distal fluid chamber. During an ablation procedure, the ultrasonic imaging sensors can be tasked to generate a number of ultrasonic images that can be displayed on a user interface.
Abstract translation: 公开了用于超声成像解剖结构并在体内进行消融治疗的装置和系统。 组合消融和超声成像探头包括消融电极尖端，其包括被配置为递送消融能量的消融电极，以及多个超声成像传感器，其构造成用于使探针周围的组织成像。 超声波成像传感器通过尖端插入件支撑在尖端的内部，并且通过穿过尖端形成的声学开口传送超声波。 尖端插入物将尖端内的内腔分成近端流体腔和远侧流体腔。 在消融过程中，可以使超声波成像传感器产生可以在用户界面上显示的多个超声波图像。
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公开(公告)号：US09757191B2
公开(公告)日：2017-09-12
申请号：US14498211
申请日：2014-09-26
Applicant: Boston Scientific Scimed Inc.
Inventor： Boaz Avitall , Josef V. Koblish
CPC classification number: A61B18/1492 , A61B5/0422 , A61B5/0464 , A61B5/065 , A61B5/4887 , A61B5/6852 , A61B18/1206 , A61B18/18 , A61B2018/0016 , A61B2018/00357 , A61B2018/00577 , A61B2018/00642 , A61B2018/00654 , A61B2018/00678 , A61B2018/00839 , A61B2018/00898 , A61B2018/00904 , A61B2018/00916 , A61B2018/126 , A61B2218/002
Abstract: An electrophysiology system comprises an ablation catheter, a radiofrequency generator, and a mapping processor. The ablation catheter has a tissue ablation electrode and a plurality of microelectrodes distributed about the circumference of the tissue ablation electrode and electrically isolated therefrom. The plurality of microelectrodes define a plurality of bipolar microelectrode pairs. The mapping processor is configured to acquire output signals from the bipolar microelectrode pairs, compare the output signals, and generate an output to a display providing a visual indication of a characteristic of the microelectrodes and the tissue ablation electrode relative to myocardial tissue to be mapped and/or ablated.
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8.发明申请SYSTEMS AND METHODS FOR MAKING AND USING MEDICAL ABLATION SYSTEMS HAVING MAPPING CATHETERS WITH IMPROVED ANCHORING ABILITY 审中-公开制造和使用具有改进锚定能力的地图导管的医疗系统的系统和方法公开(公告)号：US20170042601A1
公开(公告)日：2017-02-16
申请号：US15338600
申请日：2016-10-31
Applicant: Boston Scientific Scimed Inc.
Inventor： Isaac J. Kim , Josef V. Koblish , David L. McGee
CPC classification number: A61B18/02 , A61B5/0422 , A61B5/0538 , A61B5/4836 , A61B5/6853 , A61B5/6856 , A61B5/6857 , A61B18/1492 , A61B18/18 , A61B2017/00053 , A61B2017/00867 , A61B2018/00166 , A61B2018/0022 , A61B2018/00375 , A61B2018/00577 , A61B2018/00642 , A61B2018/00916 , A61B2018/0212 , A61B2018/1407
Abstract: A mapping catheter includes an elongated body for inserting into patient vasculature. A distal end of the elongated body includes a distal portion that includes a plurality of electrodes, a proximal portion disposed proximal to the distal portion, and a reduced-dimension portion disposed between the proximal and distal portions. The distal end is formed, at least in part, from a memory shape material that bends into a preformed shape upon release from a confined space. The preformed shape includes a first loop formed, at least in part, by the distal portion. The first loop is transverse to a longitudinal axis of the proximal portion. The reduced-dimension portion is configured and arranged to bend such that the reduced-dimension section advances distally through the first loop when the first loop is held in a fixed position and a force is applied distally along the longitudinal axis of the proximal portion.
Abstract translation: 映射导管包括用于插入患者脉管系统的细长体。 细长主体的远端包括远端部分，其包括多个电极，靠近远端部分设置的近端部分和设置在近端部分和远端部分之间的缩小部分。 远端至少部分地由从密闭空间释放时弯曲成预成形的记忆形状材料形成。 预成型形状包括至少部分由远端部分形成的第一环。 第一回路横向于近端部分的纵向轴线。 减小尺寸部分被构造和布置成弯曲，使得当第一环保持在固定位置并且沿着近端部分的纵向轴线向远侧施加力时，缩小尺寸部分向远侧延伸穿过第一环。
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公开(公告)号：US09370329B2
公开(公告)日：2016-06-21
申请号：US14029533
申请日：2013-09-17
Applicant: Boston Scientific Scimed, Inc.
Inventor： Zaya Tun , Isaac J. Kim , Josef V. Koblish , Minhchau N. Cao , Steve Ha
IPC: A61B5/042 , A61B18/14 , A61B5/00 , A61B18/18 , A61M5/00 , A61B18/12 , A61B5/04 , A61B17/00 , A61B18/00
CPC classification number: A61B5/6853 , A61B5/04012 , A61B5/0422 , A61B5/4836 , A61B18/1206 , A61B18/1492 , A61B18/18 , A61B2017/00044 , A61B2018/00023 , A61B2018/00136 , A61B2018/00791 , A61B2018/00839 , A61M5/00
Abstract: A system for performing mapping and ablation functions includes a catheter sized and shaped for vascular access. The catheter includes an elongate body extending between a proximal end and a distal end. A tip section positioned at the distal end of the catheter body and includes a proximal portion and a distal portion. One or more electrode structures are formed on an exterior surface of the tip section. The one or more electrode structures each includes a mapping electrode at the distal portion of the tip section and a contact pad electrically coupled to the mapping electrode.
Abstract translation: 用于执行测绘和消融功能的系统包括尺寸和形状用于血管通路的导管。 导管包括在近端和远端之间延伸的细长体。 位于导管主体的远端的尖端部分，包括近端部分和远端部分。 一个或多个电极结构形成在尖端部分的外表面上。 所述一个或多个电极结构各自包括在所述尖端部分的远端部分处的映射电极和电耦合到所述映射电极的接触焊盘。
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10.发明申请PRESHAPED ABLATION CATHETER FOR ABLATING PULMONARY VEIN OSTIA WITHIN THE HEART 审中-公开用于在心脏中排出肺动脉的预处理导管公开(公告)号：US20160066993A1
公开(公告)日：2016-03-10
申请号：US14942906
申请日：2015-11-16
Applicant: Boston Scientific Scimed Inc.
Inventor： Boaz Avitall , Josef V. Koblish
CPC classification number: A61B18/1492 , A61B5/6852 , A61B2017/00318 , A61B2017/00323 , A61B2017/00331 , A61B2017/00867 , A61B2018/00375 , A61M25/0041 , A61M25/0144 , A61M25/0147 , A61M25/0152 , A61M2025/0161 , C08L2201/12
Abstract: Catheters and methods are provided for performing medical procedures. The catheter comprises an elongated flexible integrated catheter body having proximal and distal shaft portions, a central support positioned inside the distal shaft and at least one operative element carried by the distal shaft portion. The distal shaft portion has a proximal section configured to be internally actuated to form a simple curve with an apex that can be inserted into the vessel ostium, an intermediate section pre-shaped to form a curve that bends opposite the simple curve, and a distal section configured to be placed into a non-radial relationship with the vessel ostium when the apex of the simple curve is inserted into the vessel ostium.
Abstract translation: 提供导管和方法用于执行医疗程序。 导管包括细长的柔性整体导管主体，其具有近端和远端轴部分，位于远端轴内的中心支撑件和由远侧轴部分承载的至少一个操作元件。 远侧轴部具有构造成内部致动的近端部分，以形成具有可插入血管口的顶点的简单曲线，预成形以形成弯曲与简单曲线相对的曲线的中间部分，以及远端 截面构造成当简单曲线的顶点插入血管口时，与血管口放置成非径向关系。
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