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26 条记录 (耗时 0.057 秒)

    Furanone derivatives
    7.
    发明授权
    Furanone derivatives 有权
    呋喃酮衍生物

    公开(公告)号：US07985771B2

    公开(公告)日：2011-07-26

    申请号：US10630170

    申请日：2003-07-30

    申请人： Sekhar Boddupalli ,  Gail Walkinshaw ,  Bing Wang

    发明人： Sekhar Boddupalli ,  Gail Walkinshaw ,  Bing Wang

    IPC分类号： A01N34/08 ,  A01N51/00 ,  A01N43/00 ,  A01N43/54 ,  A01N43/78 ,  A01N43/64 ,  C07D249/00 ,  C07D307/00 ,  C07D403/00

    CPC分类号： A61K31/41 ,  A61K31/425 ,  Y10S514/859 ,  Y10S514/863

    摘要： The invention relates to a method of treating with furanone derivatives and the pharmaceutically acceptable salts thereof, one or more conditions of the skin, in particular regulating skin condition, regulating signs of skin aging, treating a number of conditions such as contact dermatitis, skin irritation, rosacea, acne, psoriasis, and preventing and protecting skin tissue against age-related damage or damage resulting from insults such as harmful (UV) radiation or environmental pollution, stress and fatigue.

    摘要翻译： 本发明涉及用呋喃酮衍生物及其药学上可接受的盐，皮肤的一种或多种条件，特别是调节皮肤状况，调节皮肤老化迹象，治疗诸如接触性皮炎，皮肤刺激等症状的方法 ，红斑痤疮，痤疮，牛皮癣，以及预防和保护皮肤组织免受由于有害（UV）辐射或环境污染，压力和疲劳等侮辱引起的年龄相关损害或损害。

    Chroman derivatives as lipoxygenase inhibitors
    10.
    发明申请
    Chroman derivatives as lipoxygenase inhibitors 审中-公开
    色甘酸衍生物作为脂氧合酶抑制剂

    公开(公告)号：US20060193797A1

    公开(公告)日：2006-08-31

    申请号：US11349813

    申请日：2006-02-07

    申请人： Wei Zhang ,  Jian Chen ,  Sekhar Boddupalli

    发明人： Wei Zhang ,  Jian Chen ,  Sekhar Boddupalli

    IPC分类号： A61K8/49 ,  C07D311/04 ,  A61K31/353

    CPC分类号： A61K8/498 ,  A61K31/353 ,  A61K2800/782 ,  A61Q19/00 ,  C07D311/22 ,  C07D311/68 ,  C07D311/70 ,  C07D335/06

    摘要： The present invention is concerned with certain novel derivatives of Formula I: wherein X and R1 to R10 are as described in the specification, and where either R5 is OH, —NRdORa or —NRd—NRbRc, or R7 is —NRdORa or —NRd—NRbRc, or C═R7R8 is C═NORa or C═N—NRbRc, which may be useful in the manufacture of pharmaceutical compositions for treating disorders mediated by lipoxygenases. They may also be useful in the manufacture of skin care and/or pharmaceutical compositions for the treatment of lipoxygenase mediated disorders.

    摘要翻译： 本发明涉及式I的某些新型衍生物：其中X和R 1至R 10如说明书中所述，并且其中R 5 其中R 1，R 2，R 3，R 4，R 4，R 4， 或者R 7是-NR d或-NR 11或-NR 6 或者是CR 8和C 8以及C 8和R 8是C或N 其可用于制备用于治疗由脂肪氧合酶介导的病症的药物组合物。 它们也可用于制备用于治疗脂氧合酶介导的病症的皮肤护理和/或药物组合物。