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公开(公告)号：US20180299475A1
公开(公告)日：2018-10-18
申请号：US15943362
申请日：2018-04-02
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Yochanan Uri , Igor KOCHETKOV , Shai AHARON , Itay BARAK , Uri ISSMAN
Abstract: Fraction collector dispensers and methods of using such dispensers are provided. In one embodiment, the dispenser includes an inlet for receiving liquid from a liquid source, wherein the inlet is in fluid communication with an outlet from which liquid is dispensed into a receptacle; and a reservoir in fluid communication with a flow path between the inlet and outlet, wherein the reservoir comprises trapped air therein and is configured to receive liquid during movement of the dispenser between receptacles or during movement of receptacles between dispense positions, wherein the dispenser is moveable between a first receptacle and a second receptacle or the receptacles are moveable between dispense positions.
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公开(公告)号：US09354179B2
公开(公告)日：2016-05-31
申请号：US13911115
申请日：2013-06-06
Applicant: Bio-Rad Laboratories Inc.
Inventor： Yochanan Uri , Boaz Ran , Ariel G. Notcovich , Shay Nimri
CPC classification number: G01N21/553 , G01N21/253 , G01N21/658 , G01N33/54373 , G01N2021/0328 , G01N2201/0407 , G01N2201/0484 , G01N2201/062
Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.
Abstract translation: 一种用于光学检测系统的尖端，用于使用从分析物结合到所述尖端内部的检测表面反射的光来分析吸入所述尖端的流体样品中的分析物，所述检测表面包括第一检测表面和位于 相同的流动路径，没有可分离它们的可控阀，其中第一和第二检测表面具有不同的表面化学性质。
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公开(公告)号：US10359397B2
公开(公告)日：2019-07-23
申请号：US14968400
申请日：2015-12-14
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Yochanan Uri , Uri Issman , Igor Kochetkov , Itay Barak , Shai Aharon , Shai Nimri
IPC: G01N27/447 , G01N33/543
Abstract: Horizontal gel electrophoresis devices and methods of extracting a gel from a gel housing are provided. The devices allow for extraction of gels without having to open the housing comprising the gel. The devices include gel cassettes that simplify the automation of gel electrophoresis and electroblotting of proteins. Also provided are devices that allow for horizontal gel electrophoresis without the need to from a liquid seal between the buffer reservoir and the gel housing. Also described are methods for extracting a gel from a housing without opening the housing.
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公开(公告)号：US20160006910A1
公开(公告)日：2016-01-07
申请号：US14789717
申请日：2015-07-01
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Yochanan Uri , Boaz Ran , Itay Barak , Steven Swihart , Evan Thrush
IPC: H04N5/225
CPC classification number: H04N5/2252 , G01N21/76 , G01N21/763 , G01N2201/0221
Abstract: Provided herein are imaging cassettes for detecting a luminescent and/or radioactive signals. Such cassettes are useful in common biological assays, e.g., immunoassays, nucleotide detection assays, and other affinity assays.
Abstract translation: 本文提供了用于检测发光和/或放射性信号的成像盒。 这样的盒可用于常见的生物测定，例如免疫测定，核苷酸检测测定和其他亲和测定。
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公开(公告)号：US12201974B2
公开(公告)日：2025-01-21
申请号：US16984852
申请日：2020-08-04
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Yochanan Uri , Itay Barak , Robert Lovchik , David P. Taylor , Marcel Buerge , Govind V. Kaigala
IPC: B01L3/00
Abstract: The present disclosure is notably directed to a microfluidic probe head (202), or MFP head, comprising a processing surface (204) having liquid injection and liquid aspiration apertures, as well as projections (205) extending from the processing surface (204). The arrangement of injection and aspiration apertures provides for a hydrodynamic flow confinement within a processing region that is formed between the processing surface (204) and a substrate (104) or sample surface (for example, the bottom of a microtiter plate sample well (102)), typically located beneath the processing surface (204). The disclosure is further directed to related microfluidic probe devices, and methods of operation of such an MFP head, notably to deposit cells on a surface.
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Patent Agency Ranking
6.发明申请HORIZONTAL ELECTROPHORESIS SEPARATION DEVICE WITHOUT SEAL AND METHOD OF EXTRACTING GEL WITHOUT OPENING CASSETTE 审中-公开没有密封的水平电泳分离装置和不开放CASSETTE提取凝胶的方法公开(公告)号：US20160299099A1
公开(公告)日：2016-10-13
申请号：US14968400
申请日：2015-12-14
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Yochanan Uri , Uri Issman , Igor Kochetkov , Itay Barak , Shai Aharon , Shai Nimri
IPC: G01N27/447 , G01N33/543
CPC classification number: G01N27/44756 , G01N27/44721 , G01N27/44726 , G01N27/44739 , G01N27/44743 , G01N27/44782 , G01N33/54366
Abstract: Horizontal gel electrophoresis devices and methods of extracting a gel from a gel housing are provided. The devices allow for extraction of gels without having to open the housing comprising the gel. The devices include gel cassettes that simplify the automation of gel electrophoresis and electroblotting of proteins. Also provided are devices that allow for horizontal gel electrophoresis without the need to from a liquid seal between the buffer reservoir and the gel housing. Also described are methods for extracting a gel from a housing without opening the housing.
Abstract translation: 提供了水凝胶电泳装置和从凝胶壳体提取凝胶的方法。 该装置允许提取凝胶，而不必打开包含凝胶的壳体。 该装置包括凝胶盒，其简化了凝胶电泳的自动化和蛋白质的电印迹。 还提供了允许水平凝胶电泳而不需要在缓冲储存器和凝胶壳体之间的液体密封的装置。 还描述了在不打开壳体的情况下从壳体中提取凝胶的方法。
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公开(公告)号：US11480565B2
公开(公告)日：2022-10-25
申请号：US16900577
申请日：2020-06-12
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Shai Nimri , Yochanan Uri , Boaz Ran
Abstract: An instrument for detecting signal from a biological sample includes a pipettor module configured to hold a plurality of pipettes in respective pipette positions, to hold liquid in one or more pipette tips, and to pipette liquid in and out of the one or more pipette tips. Each of the one or more pipette tips has a pipette tip point. The instrument further includes one or more magnets positioned such that each of the one or more pipette tips is adjacent one of the one or more magnets.
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公开(公告)号：US09933565B2
公开(公告)日：2018-04-03
申请号：US15211728
申请日：2016-07-15
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Steve Swihart , Evan Thrush , Yochanan Uri , Boaz Ran , Itay Barak , Kevin McDonald
IPC: G02B6/08 , G02B5/22 , G01N21/64 , G02B5/28 , G01N27/447
CPC classification number: G02B6/08 , G01N21/6454 , G01N27/44721 , G01N2021/6484 , G02B5/22 , G02B5/28
Abstract: Devices, systems, methods, and kits for contact imaging are provided. A contact imaging device includes an imaging sensor, a fixed fiber faceplate mechanically coupled to the imaging sensor, and an optical filtering layer mechanically coupled to the fixed fiber faceplate. The optical filtering layer can include an interference filter, an absorptive filter, and/or a removable fiber faceplate. The contact imaging device can be used to image fluorescent samples by filtering out excitation light on the basis of wavelength and/or angle of incidence.
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公开(公告)号：US09829434B2
公开(公告)日：2017-11-28
申请号：US15070211
申请日：2016-03-15
Applicant: Bio-Rad Laboratories Inc.
Inventor： Yochanan Uri , Boaz Ran , Ariel G. Notcovich , Shay Nimri
IPC: G01N21/01 , G01N21/65 , G01N21/25 , G01N21/552 , G01N33/543 , G01N21/03
CPC classification number: G01N21/553 , G01N21/253 , G01N21/658 , G01N33/54373 , G01N2021/0328 , G01N2201/0407 , G01N2201/0484 , G01N2201/062
Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.
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公开(公告)号：US09794454B2
公开(公告)日：2017-10-17
申请号：US14789717
申请日：2015-07-01
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Yochanan Uri , Boaz Ran , Itay Barak , Steven Swihart , Evan Thrush
CPC classification number: H04N5/2252 , G01N21/76 , G01N21/763 , G01N2201/0221
Abstract: Provided herein are imaging cassettes for detecting a luminescent and/or radioactive signals. Such cassettes are useful in common biological assays, e.g., immunoassays, nucleotide detection assays, and other affinity assays.
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