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公开(公告)号:US20060121459A1
公开(公告)日:2006-06-08
申请号:US10504973
申请日:2003-02-18
申请人: Narinder Chawla , Henry Yue , Thomas Richardson , Joseph Marquis , Patricia Lehr-Mason , Ann Gorvad , Shanya Becha , Amy Kable , Anita Swarnakar , Pei Jin , Phillip Hawkins , David Chien , Jayalaxmi Ramkumar , Uyen Tran , April Hafalia , Mariah Baughn , Soo Lee , Xin Jiang , Alan Jackson , Reena Khare , Sean Bulloch
发明人: Narinder Chawla , Henry Yue , Thomas Richardson , Joseph Marquis , Patricia Lehr-Mason , Ann Gorvad , Shanya Becha , Amy Kable , Anita Swarnakar , Pei Jin , Phillip Hawkins , David Chien , Jayalaxmi Ramkumar , Uyen Tran , April Hafalia , Mariah Baughn , Soo Lee , Xin Jiang , Alan Jackson , Reena Khare , Sean Bulloch
CPC分类号: C07K14/705 , C07K16/28
摘要: Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and Q polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码REMAP的人受体和膜相关蛋白(REMAP)和Q多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与REMAP异常表达相关的紊乱的方法。
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公开(公告)号:US20050107588A1
公开(公告)日:2005-05-19
申请号:US10495148
申请日:2002-11-13
申请人: Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
发明人: Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
IPC分类号: C07K14/47 , C07K14/705 , C07H21/04
CPC分类号: C07K14/705 , C07K14/47
摘要: Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, anti-bodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译: 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白(REMAP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与REMAP异常表达相关的紊乱的方法。
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公开(公告)号:US20050191627A1
公开(公告)日:2005-09-01
申请号:US10491183
申请日:2002-09-26
申请人: Junming Yang , Aina Dyung Lu , Henry Yue , Vicki Elliott , Bridget Warren , Brendan Duggan , Ian Forsythe , Ernestine Lee , April Hafalia , Jayalaxmi Ramkumar , Narinder Chawla , Mariah Baughn , Shanya Becha , Ann Gorvad , Uyen Tran , Joana Li , Monique Yao , Craig Ison , Jennifer Griffin , Soo Lee , Hsin-Ru Chang , Brooke Emerling , Tom Tang , Preeti Lal , Amy Kable , Joseph Marquis , Xin Jiang , Alan Jackson , Yeganeh Zebarjadian , Anita Swarnakar , Amy Wilson , Pei Jin , Thomas Richardson , Umesh Bhatia , John Burrill , Sally Lee , Julie Blake , Anne Ho , Wenjin Zheng , Jin Gao
发明人: Junming Yang , Aina Dyung Lu , Henry Yue , Vicki Elliott , Bridget Warren , Brendan Duggan , Ian Forsythe , Ernestine Lee , April Hafalia , Jayalaxmi Ramkumar , Narinder Chawla , Mariah Baughn , Shanya Becha , Ann Gorvad , Uyen Tran , Joana Li , Monique Yao , Craig Ison , Jennifer Griffin , Soo Lee , Hsin-Ru Chang , Brooke Emerling , Tom Tang , Preeti Lal , Amy Kable , Joseph Marquis , Xin Jiang , Alan Jackson , Yeganeh Zebarjadian , Anita Swarnakar , Amy Wilson , Pei Jin , Thomas Richardson , Umesh Bhatia , John Burrill , Sally Lee , Julie Blake , Anne Ho , Wenjin Zheng , Jin Gao
CPC分类号: C12N9/00
摘要: Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.
摘要翻译: 本发明的各种实施方案提供了识别和编码ENZM的人类酶(ENZM)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与ENZM异常表达相关的紊乱的方法。
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公开(公告)号:US20070276126A1
公开(公告)日:2007-11-29
申请号:US10524355
申请日:2003-08-12
申请人: Vicki Elliott , Reena Khare , Brooke Emerling , Amy Kable , Uyen Tran , Pei Jin , Shanya Becha , Joseph Marquis , Anita Swarnakar , Narinder Chawla , Jayalaxmi Ramkumar , April Hafalia , Soo Lee , Xin Jiang , Alan Jackson , Thomas Richardson , Julie Blake , Jonathan Wang , David Chien , Yonghong Yang
发明人: Vicki Elliott , Reena Khare , Brooke Emerling , Amy Kable , Uyen Tran , Pei Jin , Shanya Becha , Joseph Marquis , Anita Swarnakar , Narinder Chawla , Jayalaxmi Ramkumar , April Hafalia , Soo Lee , Xin Jiang , Alan Jackson , Thomas Richardson , Julie Blake , Jonathan Wang , David Chien , Yonghong Yang
CPC分类号: C07K14/705 , Y02A90/26
摘要: Various embodiments of the invention provide human cell adhesion and extracellular matrix proteins (CADECM) and polynucleotides which identify and encode CADECM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CADECM.
摘要翻译: 本发明的各种实施方案提供了识别和编码CADECM的人细胞粘附和细胞外基质蛋白(CADECM)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与CADECM异常表达相关的紊乱的方法。
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公开(公告)号:US20050118594A1
公开(公告)日:2005-06-02
申请号:US10498788
申请日:2002-12-12
申请人: Narinder Chawla , Soo Lee , Huijun Ring , Ernestine Lee , Ian Forsythe , Reena Khare , Uyen Tran , Amy Kable , Thomas Richardson , Brooke Emerling , Erika Lindquist , Mariah Baughn , April Hafalia , Pei Jin , Anita Swarnakar , Joana Li , Joseph Marquis , Ann Gorvad , William Sprague , Shanya Becha , Vicki Elliott
发明人: Narinder Chawla , Soo Lee , Huijun Ring , Ernestine Lee , Ian Forsythe , Reena Khare , Uyen Tran , Amy Kable , Thomas Richardson , Brooke Emerling , Erika Lindquist , Mariah Baughn , April Hafalia , Pei Jin , Anita Swarnakar , Joana Li , Joseph Marquis , Ann Gorvad , William Sprague , Shanya Becha , Vicki Elliott
CPC分类号: C07K14/4702 , A61K38/00 , C12N9/00
摘要: Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode-ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.
摘要翻译: 本发明的各种实施方案提供了识别和编码ENZM的人类酶(ENZM)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与ENZM异常表达相关的紊乱的方法。
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公开(公告)号:US20070124581A1
公开(公告)日:2007-05-31
申请号:US10513957
申请日:2003-05-06
申请人: Reena Khare , Vicki Elliott , Joseph Marquis , Jayalaxmi Ramkumar , Narinder Chawla , Patricia Mason , April Hafalia , Anita Swarnakar , Pei Jin , Shanya Becha , Amy Kable , Uyen Tran , Mariah Baughn , Neil Burford , Richard Graul , Brooke Emerling , William Sprague , Jennifer Griffin , Craig Ison
发明人: Reena Khare , Vicki Elliott , Joseph Marquis , Jayalaxmi Ramkumar , Narinder Chawla , Patricia Mason , April Hafalia , Anita Swarnakar , Pei Jin , Shanya Becha , Amy Kable , Uyen Tran , Mariah Baughn , Neil Burford , Richard Graul , Brooke Emerling , William Sprague , Jennifer Griffin , Craig Ison
IPC分类号: H04L9/00
CPC分类号: C07K14/47 , A61K48/00 , G01N33/5014 , G01N2500/04
摘要: Various embodiments of the invention provide human cell adhesion and extracellular matrix proteins (CADECM) and polynucleotides which identify and encode CADECM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CADECM.
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公开(公告)号:US20050176944A1
公开(公告)日:2005-08-11
申请号:US10487092
申请日:2002-08-16
申请人: Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
发明人: Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
IPC分类号: G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P5/00 , A61P5/14 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07H21/04 , C07K1/22 , C07K14/47 , C07K16/18 , C07K16/46 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/12 , C12N9/14 , C12N9/16 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/00 , C12Q1/32 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00
CPC分类号: C07K14/4702 , A61K38/00 , C07K14/47 , G01N2500/04
摘要: Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译: 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子(INTSIG)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与INTSIG的异常表达相关的紊乱的方法。
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公开(公告)号:US20050064543A1
公开(公告)日:2005-03-24
申请号:US10487078
申请日:2002-08-15
申请人: Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
发明人: Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
IPC分类号: G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61P9/00 , A61P25/00 , A61P29/00 , A61P37/06 , A61P43/00 , C07K1/22 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/46 , C07K19/00 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/11 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/00
CPC分类号: C07K14/47 , A01K2217/05 , A61K38/00 , C07K14/705 , C12N9/1205 , C12N9/16 , C12N9/6421
摘要: Various embodiments of the invention provide human secreted proteins(SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其它实施方案提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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9.
公开(公告)号:US20050048490A1
公开(公告)日:2005-03-03
申请号:US10491213
申请日:2002-09-26
申请人: Yalda Azimzai , Mariah Baughn , Shanya Becha , Mark Borowsky , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ameena Gandhi , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Amu Kable , Daniel Kalafus , Patircia Lehr-Mason , Dyung Aina Lu , Joseph Marquis , Danniel Nguyen , Jayalaxmi Ramkumar , Thomas Richardson , Stephanie Kareht , Anita Swarnakar , Y Tom Tang , Uyen Tran , Bridget Warren , Yuming Xu , Monique Yao , Huibin Yue , Henry Yue
发明人: Yalda Azimzai , Mariah Baughn , Shanya Becha , Mark Borowsky , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ameena Gandhi , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Amu Kable , Daniel Kalafus , Patircia Lehr-Mason , Dyung Aina Lu , Joseph Marquis , Danniel Nguyen , Jayalaxmi Ramkumar , Thomas Richardson , Stephanie Kareht , Anita Swarnakar , Y Tom Tang , Uyen Tran , Bridget Warren , Yuming Xu , Monique Yao , Huibin Yue , Henry Yue
CPC分类号: G01N33/74 , C07H21/04 , C07K14/4747 , G01N2500/00
摘要: Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides whichidentify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译: 本发明的各种实施方案提供与细胞生长,分化和死亡(CGDD)相关的人类蛋白质和识别和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号:US20050107293A1
公开(公告)日:2005-05-19
申请号:US10489695
申请日:2002-09-13
申请人: William Sprague , Narinder Chawla , Bridget Warren , Y. Tom Tang , Vicki Elliott , Joseph Marquis , Joana Li , Jennifer Griffin , Kimberly Gietzen , Junming Yang , Dyung Lu , Brooke Emerling , Brendan Duggan , Thomas Richardson , Soo Lee , Jayalaxmi Ramkumar , Shanya Becha , Patricia Mason , Anita Swarnakar , Uyen Tran , Amy Kable , April Hafalia , Reena Khare
发明人: William Sprague , Narinder Chawla , Bridget Warren , Y. Tom Tang , Vicki Elliott , Joseph Marquis , Joana Li , Jennifer Griffin , Kimberly Gietzen , Junming Yang , Dyung Lu , Brooke Emerling , Brendan Duggan , Thomas Richardson , Soo Lee , Jayalaxmi Ramkumar , Shanya Becha , Patricia Mason , Anita Swarnakar , Uyen Tran , Amy Kable , April Hafalia , Reena Khare
IPC分类号: G01N33/53 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/18 , A61P3/00 , A61P5/00 , A61P5/24 , A61P5/38 , A61P9/00 , A61P15/00 , A61P17/00 , A61P25/00 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/06 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/566 , G01N33/577 , G01N37/00 , A61K38/45 , C07H21/04 , C12N9/12
CPC分类号: C07K14/47 , A01K2217/05 , A61K38/00 , C12N9/6421
摘要: Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.a.
摘要翻译: 本发明的各种实施方案提供了识别和编码PMMM的人蛋白质修饰和维持分子(PMMM)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与PMMM异常表达相关的紊乱的方法。
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