METHOD OF MANUFACTURING CORELESS SUBSTRATE
    2.
    发明申请
    METHOD OF MANUFACTURING CORELESS SUBSTRATE 审中-公开
    制造无害基板的方法

    公开(公告)号:US20120324723A1

    公开(公告)日:2012-12-27

    申请号:US13448869

    申请日:2012-04-17

    IPC分类号: H05K3/00

    摘要: The present invention has been made in an effort to provide a method of manufacturing a coreless substrate that forms an opening by patterning a dry film for forming the opening onto one surface of a carrier, separating the carrier from the substrate, and removing only the dry film for forming the opening. In the present invention, since the pad can be exposed by removing only the dry film for forming the opening, a process time for forming the opening can be reduced and since a process is simple, a cost is saved.

    摘要翻译: 本发明的目的在于提供一种制造无芯基板的方法,该无芯基板通过在载体的一个表面上形成开口的干膜图案化而形成开口,将载体与基板分离,并且仅去除干燥的 用于形成开口的胶片。 在本发明中,由于仅通过除去用于形成开口的干膜来露出垫,所以可以减少形成开口的处理时间,并且由于处理简单,因此节约了成本。

    METHOD FOR PREPARING RECOMBINANT PEPTIDE FROM SPIDER VENOM AND METHOD FOR RELIEVING PAIN
    3.
    发明申请
    METHOD FOR PREPARING RECOMBINANT PEPTIDE FROM SPIDER VENOM AND METHOD FOR RELIEVING PAIN 审中-公开
    从天花板制备重组蛋白的方法及缓解疼痛的方法

    公开(公告)号:US20120015886A1

    公开(公告)日:2012-01-19

    申请号:US12907475

    申请日:2010-10-19

    IPC分类号: A61K38/17 A61P29/00

    CPC分类号: C07K14/43518 C12N15/815

    摘要: The present invention relates to a method for producing a recombinant, spider toxin peptide and analgesic compositions containing said peptide. More specifically, the present invention relates to a method in which the gene for GsMTx4 is subcloned into a vector, so that it is linked to a secretion signal sequence of the alpha factor and under the control of methanol-inducible alcohol oxidase (AOX) promoter to construct a recombinant yeast expression plasmid. Yeast cells are transformed with this plasmid to produce the GsMTx4 peptide and analgesic compositions containing said peptide. The recombinant yeast expression system of the present invention affords a more stable method for producing GsMTx4 than its natural route. Thus the GsMTx4 peptide and its derivatives produced by the method of this invention can be used in the cure of related diseases such as heart failure as the peptide specifically inhibits mechanosensitive ion channels.

    摘要翻译: 本发明涉及一种生产含有所述肽的重组蜘蛛毒素肽和镇痛组合物的方法。 更具体地,本发明涉及将GsMTx4的基因亚克隆到载体中的方法,使其与α因子的分泌信号序列连接并在甲醇诱导型醇氧化酶(AOX)启动子的控制下 构建重组酵母表达质粒。 用该质粒转化酵母细胞以产生含有所述肽的GsMTx4肽和镇痛组合物。 本发明的重组酵母表达系统提供比其自然途径更稳定的产生GsMTx4的方法。 因此,通过本发明方法产生的GsMTx4肽及其衍生物可用于治疗诸如心力衰竭等相关疾病,因为该肽特异性抑制机械敏感离子通道。

    PRINTED CIRCUIT BOARD HAVING A BUMP AND A METHOD OF MANUFACTURING THE SAME
    4.
    发明申请
    PRINTED CIRCUIT BOARD HAVING A BUMP AND A METHOD OF MANUFACTURING THE SAME 审中-公开
    具有BUMP的印刷电路板及其制造方法

    公开(公告)号:US20110048786A1

    公开(公告)日:2011-03-03

    申请号:US12870137

    申请日:2010-08-27

    IPC分类号: H05K1/11 H05K3/10

    摘要: Disclosed herein is a printed circuit board having a bump and a method of manufacturing the same. The printed circuit board having a bump includes an insulating layer into which an inner circuit layer is impregnated; a protective layer that is formed under the insulating layer and has an opening exposing a pad unit of the inner circuit layer; and a bump that is integrally formed with the pad unit and is protruded from the inner side of the protective layer to the outside of the protective layer through the opening. The bump is integrally formed with the pad unit, thereby improving bonding strength between the bump and the printed circuit board, and the surface area of the bump is formed to be wide, thereby improving bonding strength between a solder ball and the printed circuit board.

    摘要翻译: 这里公开了具有凹凸的印刷电路板及其制造方法。 具有凸块的印刷电路板包括绝缘层,内部电路层被浸渍到该绝缘层中; 形成在所述绝缘层之下并具有暴露所述内部电路层的焊盘单元的开口的保护层; 以及与所述垫单元一体形成并从所述保护层的内侧通过所述开口突出到所述保护层的外侧的凸块。 凸块与焊盘单元一体地形成,从而提高凸块和印刷电路板之间的接合强度,并且凸块的表面积形成为宽,从而提高焊球和印刷电路板之间的接合强度。

    Method For Preparing Recombinant Peptide From Spider Venom and Analgesic Composition Containing The Peptide
    5.
    发明申请
    Method For Preparing Recombinant Peptide From Spider Venom and Analgesic Composition Containing The Peptide 审中-公开
    从蜘蛛毒液制备重组肽的方法和含有肽的止痛组合物

    公开(公告)号:US20090023183A1

    公开(公告)日:2009-01-22

    申请号:US12090664

    申请日:2006-10-18

    CPC分类号: C07K14/43518 C12N15/815

    摘要: The present invention relates to a method for producing a recombinant, spider toxin peptide and analgesic compositions containing said peptide. More specifically, the present invention relates to a method in which the gene for GsMTx4 is subcloned into a vector, so that it is linked to a secretion signal sequence of the alpha factor and under the control of methanol-inducible alcohol oxidase (AOX) promoter to construct a recombinant yeast expression plasmid. Yeast cells are transformed with this plasmid to produce the GsMTx4 peptide and analgesic compositions containing said peptide. The recombinant yeast expression system of the present invention affords a more stable method for producing GsMTx4 than its natural route. Thus the GsMTx4 peptide and its derivatives produced by the method of this invention can be used in the cure of related diseases such as heart failure as the peptide specifically inhibits mechanosensitive ion channels.

    摘要翻译: 本发明涉及一种生产含有所述肽的重组蜘蛛毒素肽和镇痛组合物的方法。 更具体地,本发明涉及将GsMTx4的基因亚克隆到载体中的方法,使其与α因子的分泌信号序列连接并在甲醇诱导型醇氧化酶(AOX)启动子的控制下 构建重组酵母表达质粒。 用该质粒转化酵母细胞以产生含有所述肽的GsMTx4肽和镇痛组合物。 本发明的重组酵母表达系统提供比其自然途径更稳定的产生GsMTx4的方法。 因此,通过本发明方法产生的GsMTx4肽及其衍生物可用于治疗诸如心力衰竭等相关疾病,因为该肽特异性抑制机械敏感离子通道。

    Carrier for manufacturing substrate and method of manufacturing substrate using the same
    7.
    发明授权
    Carrier for manufacturing substrate and method of manufacturing substrate using the same 失效
    用于制造基板的载体和使用其的制造基板的方法

    公开(公告)号:US08435376B2

    公开(公告)日:2013-05-07

    申请号:US12787300

    申请日:2010-05-25

    摘要: Disclosed herein is a carrier for manufacturing a substrate, including: a base plate; adhesive layers formed on one side or both sides of the base plate; auxiliary adhesive layers, each of which is buried in one side of each of the adhesive layers, has a smaller area than each of the adhesive layers and has lower adhesivity than each of the adhesive layers; and metal layers, each of which is formed on one side of each of the auxiliary adhesive layers, whose edges are attached to the adhesive layers, and whose other portions excluding the edges are attached to the auxiliary adhesive layers. The carrier is advantageous in that a metal layer and an auxiliary adhesive layer are attached to each other by the adhesivity of the auxiliary adhesive layer, so that it is not required to use vacuum adsorption, with the result that a process of manufacturing a substrate can be performed more stably.

    摘要翻译: 本文公开了一种用于制造基板的载体,包括:基板; 形成在基板的一侧或两侧的粘合剂层; 每个粘合剂层的一侧的辅助粘合剂层具有比每个粘合剂层更小的面积,并且具有比每个粘合剂层更低的粘附性; 以及金属层,其各自形成在每个辅助粘合剂层的一侧上,其边缘附着到粘合剂层,并且除了边缘之外的其它部分附着到辅助粘合剂层。 载体的优点在于,金属层和辅助粘合剂层通过辅助粘合剂层的粘合性彼此附接,使得不需要使用真空吸附,结果是制造基材的工艺可以 更稳定地进行。

    CARRIER FOR MANUFACTURING SUBSTRATE AND METHOD OF MANUFACTURING SUBSTRATE USING THE SAME
    8.
    发明申请
    CARRIER FOR MANUFACTURING SUBSTRATE AND METHOD OF MANUFACTURING SUBSTRATE USING THE SAME 失效
    用于制造基板的承载件及其制造方法

    公开(公告)号:US20110159282A1

    公开(公告)日:2011-06-30

    申请号:US12787300

    申请日:2010-05-25

    摘要: Disclosed herein is a carrier for manufacturing a substrate, including: a base plate; adhesive layers formed on one side or both sides of the base plate; auxiliary adhesive layers, each of which is buried in one side of each of the adhesive layers, has a smaller area than each of the adhesive layers and has lower adhesivity than each of the adhesive layers; and metal layers, each of which is formed on one side of each of the auxiliary adhesive layers, whose edges are attached to the adhesive layers, and whose other portions excluding the edges are attached to the auxiliary adhesive layers. The carrier is advantageous in that a metal layer and an auxiliary adhesive layer are attached to each other by the adhesivity of the auxiliary adhesive layer, so that it is not required to use vacuum adsorption, with the result that a process of manufacturing a substrate can be performed more stably.

    摘要翻译: 本文公开了一种用于制造基板的载体,包括:基板; 形成在基板的一侧或两侧的粘合剂层; 每个粘合剂层的一侧的辅助粘合剂层具有比每个粘合剂层更小的面积,并且具有比每个粘合剂层更低的粘附性; 以及金属层,其各自形成在每个辅助粘合剂层的一侧上,其边缘附着到粘合剂层,并且除了边缘之外的其它部分附着到辅助粘合剂层。 载体的优点在于,金属层和辅助粘合剂层通过辅助粘合剂层的粘合性彼此附接,使得不需要使用真空吸附,结果是制造基材的工艺可以 更稳定地进行。