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公开(公告)号：US07323696B2
公开(公告)日：2008-01-29
申请号：US11031983
申请日：2005-01-06
CPC分类号： B82Y5/00 , C12Q2563/155 , G01N33/54346 , G01N33/587
摘要： Beads coded with phosphor particles and methods of making and using them are provided.
摘要翻译： 提供用磷光体颗粒编码的珠子，并制作和使用它们的方法。
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2.发明授权Methods for generating pH/ionic concentration gradient near electrode surfaces for modulating biomolecular interactions 有权用于在电极表面附近产生用于调节生物分子相互作用的pH /离子浓度梯度的方法公开(公告)号：US09075041B2
公开(公告)日：2015-07-07
申请号：US13543300
申请日：2012-07-06
IPC分类号： G01N33/50 , G01N27/327 , G01N33/53
CPC分类号： G01N33/50 , G01N27/3275 , G01N33/5306
摘要： Methods of modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest from a biological sample in a biosensor having a multisite array of test sites. In particular, the methods modulate the pH or ionic concentration gradient near the electrodes in such biosensor. The methods of modulating the binding interactions provide a biosensor and analytic methods for more accurately measuring an analyte of interest in a biological sample.
摘要翻译： 在生物传感器中调节生物样品中生物分子探针或检测剂与目的分析物之间的结合相互作用的方法，该生物传感器具有多个测试位点阵列。 特别地，该方法调节这种生物传感器中电极附近的pH或离子浓度梯度。 调节结合相互作用的方法提供了生物传感器和分析方法，用于更精确地测量生物样品中感兴趣的分析物。
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公开(公告)号：US08312890B1
公开(公告)日：2012-11-20
申请号：US11252914
申请日：2005-10-18
申请人： Aldrich N. K. Lau
发明人： Aldrich N. K. Lau
IPC分类号： F16K17/14
CPC分类号： F16K99/0001 , B01L3/502738 , B01L3/502746 , B01L2200/0621 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2400/0406 , B01L2400/0415 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , B01L2400/0661 , B01L2400/0677 , B01L2400/0683 , B01L2400/082 , B01L2400/084 , B01L2400/086 , F16K99/003 , F16K99/0036 , F16K99/0057 , F16K2099/0084 , Y10S422/901 , Y10T137/0318 , Y10T137/0324 , Y10T137/1624 , Y10T137/1812 , Y10T137/2191 , Y10T137/8376 , Y10T137/8593 , Y10T137/85978 , Y10T436/143333 , Y10T436/2575
摘要： A fluid processing device, system, and method for processing a fluid, are provided. The device includes a substrate, a plurality of fluid retainment regions formed in or on the substrate, and a barrier at least partially separating two or more of the fluid retainment regions, wherein the barrier can include a solvent-dissolvable, LCST-free material.
摘要翻译： 提供了一种用于处理流体的流体处理装置，系统和方法。 该装置包括衬底，形成在衬底中或衬底上的多个流体保持区域，以及至少部分地分离两个或更多个流体保持区域的屏障，其中该阻挡层可包括溶剂可溶解的不含LCST的材料。
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公开(公告)号：US20100136701A1
公开(公告)日：2010-06-03
申请号：US12627799
申请日：2009-11-30
CPC分类号： F16K99/0001 , B01L3/502738 , B01L3/502746 , B01L2200/0621 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2400/0406 , B01L2400/0415 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , B01L2400/0661 , B01L2400/0677 , B01L2400/0683 , B01L2400/082 , B01L2400/084 , B01L2400/086 , F16K99/003 , F16K99/0036 , F16K99/0057 , F16K2099/0084 , Y10S422/901 , Y10T137/0318 , Y10T137/0324 , Y10T137/1624 , Y10T137/1812 , Y10T137/2191 , Y10T137/8376 , Y10T137/8593 , Y10T137/85978 , Y10T436/143333 , Y10T436/2575
摘要： A diagnostic device is provided that includes a plurality of retainment regions, with the retainment regions that are separated by at least one dissolvable barrier. The retainment regions can be interconnected through at least one fluid processing passageway. A retainment region can include a container such as a retainment region, well, chamber, or other receptacle, or a retainment region such as a surface on which the material is retained. The retainment regions can include a reaction retainment region, one or more reagent retainment regions, each containing unreacted reagents, and a sample retainment region. A pressure-actuated valve can be positioned in each fluid processing passageway interconnecting the one or more reagent retainment regions with the respective intermediate retainment regions interposed between each of the one or more reagent retainment regions and the reaction retainment region. The dissolvable barrier can be a fluid flow modulator in the at least one fluid processing passageway.
摘要翻译： 提供了一种诊断装置，其包括多个保持区域，其中保留区域被至少一个可溶解屏障隔开。 保持区域可以通过至少一个流体处理通道相互连接。 保持区域可以包括诸如保持区域，孔，腔室或其它容器的容器，或诸如保持材料的表面的保持区域。 保留区域可以包括反应保留区域，一个或多个试剂保留区域，每个含有未反应的试剂和样品保留区域。 压力致动阀可以定位在每个流体处理通道中，其将一个或多个试剂保留区域与插入在一个或多个试剂保留区域中的每一个和反应保留区域之间的各个中间保留区域互连。 可溶解屏障可以是至少一个流体处理通道中的流体流动调节器。
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公开(公告)号：US20100133104A1
公开(公告)日：2010-06-03
申请号：US12627824
申请日：2009-11-30
CPC分类号： F16K99/0001 , B01L3/502738 , B01L3/502746 , B01L2200/0621 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2400/0406 , B01L2400/0415 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , B01L2400/0661 , B01L2400/0677 , B01L2400/0683 , B01L2400/082 , B01L2400/084 , B01L2400/086 , F16K99/003 , F16K99/0036 , F16K99/0057 , F16K2099/0084 , Y10S422/901 , Y10T137/0318 , Y10T137/0324 , Y10T137/1624 , Y10T137/1812 , Y10T137/2191 , Y10T137/8376 , Y10T137/8593 , Y10T137/85978 , Y10T436/143333 , Y10T436/2575
摘要： A diagnostic device is provided that includes a plurality of retainment regions interconnected through at least one fluid processing passageway or separated by at least one barrier. A fluid flow modulator can be provided in the fluid processing passageway if a fluid processing passageway is provided. The barrier and/or fluid flow modulator can comprise a polysaccharide, a derivative of a polysaccharide, or a combination thereof. For example, the barrier can comprise a chitosan material.
摘要翻译： 提供了诊断装置，其包括通过至少一个流体处理通道互连或由至少一个屏障隔开的多个保持区域。 如果提供流体处理通道，流体流动调节器可以设置在流体处理通道中。 阻隔和/或流体流动调节器可以包含多糖，多糖的衍生物或其组合。 例如，阻挡层可以包含壳聚糖材料。
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6.发明授权High speed, high resolution compositions, methods, and kits for capillary electrophoresis 有权用于毛细管电泳的高速，高分辨率组合物，方法和试剂盒公开(公告)号：US06706162B1
公开(公告)日：2004-03-16
申请号：US09668960
申请日：2000-09-25
申请人： Karl O. Voss , Aldrich N. K. Lau
发明人： Karl O. Voss , Aldrich N. K. Lau
IPC分类号： B01D5702
CPC分类号： G01N27/44747 , B01D53/02 , G01N27/44791
摘要： The invention provides compositions, methods and kits for high speed, high resolution of analytes by capillary electrophoresis starting with uncoated capillaries. The compositions comprise a sieving component, comprising a non-crosslinked acrylamide polymer, and a surface interaction component, comprising at least one uncharged and non-crosslinked water-soluble silica-adsorbing polymer. Methods for employing the novel compositions in capillary electrophoresis are provided. Kits comprising the novel compositions for use in the novel methods are also provided.
摘要翻译： 本发明提供了用未经涂覆的毛细管从毛细管电泳开始高分辨率分析物的组合物，方法和试剂盒。 组合物包含筛分组分，其包含非交联的丙烯酰胺聚合物和包含至少一种不带电和非交联的水溶性二氧化硅吸附聚合物的表面相互作用组分。 提供了在毛细管电泳中使用新型组合物的方法。 还提供了包含用于新颖方法的新型组合物的试剂盒。
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7.发明授权
公开(公告)号：US5484552A
公开(公告)日：1996-01-16
申请号：US416555
申请日：1995-04-04
申请人： Mark F. Wartenberg , Harriette Atkins , Robert H. Reamey , Laurence Welsh , James Strain , Janusz Wojtowicz , Wayne Montoya , Paul S. Drzaic , John Havens , Akira Tomita , Aldrich N. K. Lau
发明人： Mark F. Wartenberg , Harriette Atkins , Robert H. Reamey , Laurence Welsh , James Strain , Janusz Wojtowicz , Wayne Montoya , Paul S. Drzaic , John Havens , Akira Tomita , Aldrich N. K. Lau
IPC分类号： G02F1/1334 , C09K19/02 , C09K19/54 , C09K19/58 , G02F1/1333 , G02F1/137 , G02F1/13
CPC分类号： C09K19/544 , C09K19/54 , C09K19/58 , G02F1/1334
摘要： A liquid crystal display is made from an encapsulated liquid crystal structure comprising a liquid crystal composition dispersed in a containment medium. Selected additives may be added to the encapsulated liquid crystal structure to improve performance characteristics such as the operating field, the hysteresis, and the voltage holding ratio.
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公开(公告)号：US5173542A
公开(公告)日：1992-12-22
申请号：US583898
申请日：1990-09-17
申请人： Aldrich N. K. Lau , Lanchi P. Vo , Frank W. Mercer
发明人： Aldrich N. K. Lau , Lanchi P. Vo , Frank W. Mercer
IPC分类号： C08G61/00 , C07C245/22 , C07C245/24 , C08G65/40 , C08K5/17 , C08K5/22 , C08K5/27 , C08L27/12 , C08L71/00 , C08L71/08 , C08L71/10 , C08L79/08 , C08L101/00 , H01B3/30 , H01L23/12 , H01L23/498 , H01L23/532 , H05K1/03 , H05K3/46
CPC分类号： C08L71/00 , C07C245/24 , C08G65/40 , C08G65/4006 , C08K5/27 , H01L23/49894 , H01L23/5329 , C08G2650/20 , C08L2203/20 , C08L2312/00 , H01L2924/0002 , H01L2924/09701 , H05K1/034 , H05K2201/015
摘要： Bistriazene compounds such as ##STR1## are useful for crosslinking polymers such as poly(imides), poly(aryl ether ketones), poly(aryl ether sulfones), poly(quinolines), poly(quinoxalines), and nonaromatic fluoropolymers having aliphatic C--H groups. Polymers crosslinked with these bistriazene compounds are useful as interlayer insulators in multilayer integrated circuit articles.
摘要翻译： 诸如聚（酰亚胺），聚（芳基醚酮），聚（芳基醚砜），聚（喹啉），聚（喹喔啉）和非芳族化合物等交联聚合物的双三烯化合物例如
+ TR 具有脂族CH基团的含氟聚合物。 与这些双三烯化合物交联的聚合物可用作多层集成电路制品中的层间绝缘体。 -
公开(公告)号：US08357282B2
公开(公告)日：2013-01-22
申请号：US12623201
申请日：2009-11-20
申请人： Aldrich N. K. Lau
发明人： Aldrich N. K. Lau
IPC分类号： B03C5/02
CPC分类号： B03C5/026 , B03C5/005 , B03C5/028 , C07K1/26 , G01N27/305
摘要： The present teachings relate to systems and methods for separation of substances such as cells, nucleic acids, and carbon nanotubes. The substances are combined with a separation medium in a liquid sample cavity, for example a microchannel, and transit through the separation by optically activated dielectrophoretic forces. The substances are advantageously labeled and visualized using a microscope and camera.
摘要翻译： 本教导涉及用于分离诸如细胞，核酸和碳纳米管的物质的系统和方法。 这些物质与液体样品腔（例如微通道）中的分离介质组合，并通过光学活化的介电电泳力穿过分离。 使用显微镜和照相机有利地将物质标记和可视化。
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公开(公告)号：US07378260B2
公开(公告)日：2008-05-27
申请号：US11096731
申请日：2005-04-01
IPC分类号： C12P19/34
CPC分类号： C12P19/34 , C12N15/1006 , C12N15/1017 , C12Q1/6848 , C12Q2527/149 , C12Q2523/308 , C12Q2521/101
摘要： The present invention provides products and methods of reducing dye artifacts from chain extension reactions.
摘要翻译： 本发明提供了从延伸反应中还原染料伪影的产物和方法。
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