-
公开(公告)号：US20230340443A1
公开(公告)日：2023-10-26
申请号：US18151122
申请日：2023-01-06
Applicant: Danisco US Inc.
Inventor： Bart C. Koops , Paula Johanna Maria Teunissen , Marco Van Brussel-Zwijnen , Martijn Scheffers , Kees-Jan Guijt , Zhengzheng Zou , Zhongmei Tang , Zhen Qian , Jing Ge , Zhenghong Zhang
CPC classification number: C12N9/242 , C12P19/02 , C12P19/14 , C12Y302/01001 , C12Y302/01003 , C12N9/2428 , C12P7/06
Abstract: Described are methods and compositions relating to granular starch-converting glucoamylases and α-amylases. The enzymes can be used to perform enzymatic starch hydrolysis of granular starch at or below the gelatinization temperature of insoluble granular starch.
-
公开(公告)号：US11130946B2
公开(公告)日：2021-09-28
申请号：US16742080
申请日：2020-01-14
Applicant: DANISCO US INC
Inventor： Pieter Van Solingen , Richard R. Bott , Wolfgang Aehle , Martijn Scheffers
Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
-
公开(公告)号：US20190002853A1
公开(公告)日：2019-01-03
申请号：US15938035
申请日：2018-03-28
Applicant: Danisco US Inc.
Inventor： Wolfgang Aehle , Piet Van Solingen , Martijn Scheffers , Richard Bott
CPC classification number: C12N9/2428 , C12N15/09 , C12Y302/01003 , Y02E50/17
Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
-
公开(公告)号：US09290753B2
公开(公告)日：2016-03-22
申请号：US14172790
申请日：2014-02-04
Applicant: Danisco US Inc.
Inventor： Wolfgang Aehle , Richard R. Bott , Martijn Scheffers , Pieter van Solingen , Casper Vroemen
CPC classification number: C12N9/2428 , C12P7/06 , C12P19/02 , C12P19/14 , Y02E50/17
Abstract: The present disclosure relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present disclosure provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions and cleaning compositions. The disclosure also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
-
5.发明申请METHOD OF USING ALPHA-AMYLASE FROM ASPERGILLUS TERREUS AND PULLULANASE FOR SACCHARIFICATION 审中-公开使用来自青蒿素和富勒烯的ALPHA-AMYLASE进行分离的方法公开(公告)号：US20160010128A1
公开(公告)日：2016-01-14
申请号：US14649807
申请日：2013-12-06
Applicant: DANISCO US INC.
Inventor： Jing Ge , Ling Hua , Martijn Scheffers , Marco Van Brussel , Casper Vroemen , Bo Zhang
CPC classification number: C12P19/14 , A21D8/042 , A23L2/382 , A23L7/107 , A23L29/35 , C11D3/386 , C12C5/004 , C12C7/04 , C12C7/16 , C12C11/003 , C12C12/04 , C12N9/242 , C12P7/06 , C12P7/14 , C12P19/02 , C12P2203/00 , C13K1/06 , C13K11/00 , D06L1/06 , Y02E50/17
Abstract: A fungal alpha-amylase is provided from Aspergillus terreus (AtAmyl). AtAmyl has an optimal pH of 4.5 and is operable at 30 75 degrees C., allowing the enzyme to be used in combination with a glucoamylase and a pullulanase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AtAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.
Abstract translation: 由Aspergillus terreus（AtAmyl）提供真菌α-淀粉酶。 AtAmyl具有4.5的最佳pH，并且在30±75℃下可操作，使酶在糖化反应中与葡糖淀粉酶和支链淀粉酶组合使用。 这消除了作为分批方法进行糖化反应的必要性，其中必须重新调节pH和温度以最佳地使用α-淀粉酶或葡糖淀粉酶。 与由来自曲霉（Aspergillus kawachii）的α-淀粉酶催化的糖化产物相比，AtAmyl还催化淀粉底物对显着富含DP2和（DP1 + DP2）的寡糖组合物的糖化。 这有助于例如在同时糖化和发酵过程中由发酵生物体利用寡糖组合物。
-
Patent Agency Ranking
公开(公告)号：US20140087442A1
公开(公告)日：2014-03-27
申请号：US14015740
申请日：2013-08-30
Applicant: Danisco US Inc.
Inventor： Wolfgang Aehle , Richard R. Bott , Igor Nikoaev , Martijn Scheffers , Piet Van Solingen , Casper Vroemen
IPC: C12N9/34
CPC classification number: C12N9/2428 , C12N15/09 , C12Y302/01003 , Y02E50/17
Abstract: The present invention relates to glucoamylase variants. In particular, the invention relates to variants in the starch binding domain (SBD) of a glucoamylase. The invention also relates to variants having altered properties (e.g., improved thermostability and/or increased specific activity) as compared to a corresponding parent glucoamylase. The present invention also provides enzyme compositions comprising the variant glucoamylases; DNA constructs comprising polynucleotides encoding the variants; and methods of producing the glucoamylase variants in host cells.
Abstract translation: 本发明涉及葡糖淀粉酶变体。 特别地，本发明涉及葡糖淀粉酶的淀粉结合结构域（SBD）中的变体。 本发明还涉及与相应的母体葡糖淀粉酶相比具有改变的性质（例如，改善的热稳定性和/或增加的比活性）的变体。 本发明还提供了包含变体葡糖淀粉酶的酶组合物; 包含编码变体的多核苷酸的DNA构建体; 以及在宿主细胞中产生葡糖淀粉酶变体的方法。
-
公开(公告)号：US10563187B2
公开(公告)日：2020-02-18
申请号：US15938035
申请日：2018-03-28
Applicant: Danisco US Inc.
Inventor： Wolfgang Aehle , Piet Van Solingen , Martijn Scheffers , Richard Bott
Abstract: The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
-
公开(公告)号：US20190010473A1
公开(公告)日：2019-01-10
申请号：US16064518
申请日：2016-12-20
Applicant: Danisco US Inc.
Inventor： Bart C. Koops , Paula Johanna Maria Teunissen , Marco Van Brussel-Zwijnen , Martijn Scheffers , Kees-Jan Guijt , Zhengzheng Zou , Zhongmei Tang , Zhen Qian , Jing Ge , Zhenghong Zhang
Abstract: Described are methods and compositions relating to granular starch-converting glucoamylases and α-amylases. The enzymes can be used to perform enzymatic starch hydrolysis of granular starch at or below the gelatinization temperature of insoluble granular starch.
-
公开(公告)号：US20190002854A1
公开(公告)日：2019-01-03
申请号：US16064577
申请日：2016-12-20
Applicant: Bart C. KOOPS , Paula Johanna Maria TEUNISSEN , Marco VAN BRUSSEL-ZWIJNEN , Martijn SCHEFFERS , Kees-Jan GUIJT , Zhengzheng ZOU , Zhongmei TANG , Zhen QIAN , Jing GE , Zhenghong ZHANG , Danisco US Inc.
Inventor： Bart C. Koops , Paula Johanna Maria Teunissen , Marco Van Brussel-Zwijnen , Martijn Scheffers , Kees-Jan Guijt , Zhengzheng Zou , Zhongmei Tang , Zhen Qian , Jing Ge , Zhenghong Zhang
Abstract: Described are methods and compositions relating to granular starch-converting glucoamylases and α-amylases. The enzymes can be used to perform enzymatic starch hydrolysis of granular starch at or below the gelatinization temperature of insoluble granular starch.
-
10.发明授权公开(公告)号：US09765374B2
公开(公告)日：2017-09-19
申请号：US14649173
申请日：2013-12-05
Applicant: Danisco US Inc.
Inventor： Ling Hua , Martijn Scheffers , Marco Van Brussel , Casper Vroemen , Bo Zhang , Zhengong Zhang
IPC: C12P7/06 , C12P19/14 , A21D8/04 , C11D3/386 , D06L1/06 , C12C5/00 , C12N9/30 , C12N9/44 , C12C11/00 , C12P19/02 , A23L7/104
CPC classification number: C12P19/14 , A21D8/042 , A23L7/107 , A23V2002/00 , C11D3/386 , C12C5/004 , C12C11/003 , C12N9/242 , C12N9/246 , C12P7/06 , C12P19/02 , C12Y302/01001 , C12Y302/01068 , D06L1/06 , Y02E50/17
Abstract: A fungal alpha-amylase is provided from Aspergillus fumigatus (AfAmyl). AfAmyl has an optimal pH of 3.5 and is operable at 30-75 degrees C., allowing the enzyme to be used in combination with a glucoamylase and an isoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AfAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DPI+DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.
-
-
-
-
-
-
-
-
-
Search Results
20
records
(took 0.044 seconds)
