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    Cardiac stimulation apparatus and method for the control of hypertension
    3.
    发明授权
    Cardiac stimulation apparatus and method for the control of hypertension 有权
    心脏刺激装置及控制高血压的方法

    公开(公告)号：US08428729B2

    公开(公告)日：2013-04-23

    申请号：US13281742

    申请日：2011-10-26

    申请人： Robert S. Schwartz ,  Robert A. Van Tassel

    发明人： Robert S. Schwartz ,  Robert A. Van Tassel

    IPC分类号： A61N1/365

    CPC分类号： A61N1/36514 ,  A61N1/3627 ,  A61N1/36564

    摘要： A method that electrically stimulates a heart muscle to alter the ejection profile of the heart, to control the mechanical function of the heart and reduce the observed blood pressure of the patient. The therapy may be invoked by an implantable blood pressure sensor associated with a pacemaker like device. In some cases, where a measured pretreatment blood pressure exceeds a treatment threshold, a patient's heart may be stimulated with an electrical stimulus timed relative to the patient's cardiac ejection cycle. This is done to cause dyssynchrony between at least two cardiac chambers or within a cardiac chamber, which alters the patient's cardiac ejection profile from a pretreatment cardiac ejection profile. This has the effect of reducing the patient's blood pressure from the measured pretreatment blood pressure.

    摘要翻译： 一种电刺激心肌以改变心脏的射血分布，控制心脏的机械功能并降低观察到的患者血压的方法。 该治疗可以由与起搏器相似的装置相关联的可植入血压传感器来调用。 在一些情况下，在测量的预处理血压超过治疗阈值的情况下，可以以相对于患者的心脏射血周期计时的电刺激来刺激患者的心脏。 这是为了在至少两个心室之间或心室内引起不同步，其改变患者的心脏射血分布从预处理的心脏射血分布。 这具有从测量的预处理血压降低患者的血压的效果。

    Cardiac Stimulation Apparatus And Method For The Control Of Hypertension
    4.
    发明申请
    Cardiac Stimulation Apparatus And Method For The Control Of Hypertension 有权
    心脏刺激装置及控制高血压的方法

    公开(公告)号：US20120041502A1

    公开(公告)日：2012-02-16

    申请号：US13281742

    申请日：2011-10-26

    申请人： Robert S. Schwartz ,  Robert A. Van Tassel

    发明人： Robert S. Schwartz ,  Robert A. Van Tassel

    IPC分类号： A61N1/362

    CPC分类号： A61N1/36514 ,  A61N1/3627 ,  A61N1/36564

    摘要： A method that electrically stimulates a heart muscle to alter the ejection profile of the heart, to control the mechanical function of the heart and reduce the observed blood pressure of the patient. The therapy may be invoked by an implantable blood pressure sensor associated with a pacemaker like device. In some cases, where a measured pretreatment blood pressure exceeds a treatment threshold, a patient's heart may be stimulated with an electrical stimulus timed relative to the patient's cardiac ejection cycle. This is done to cause dyssynchrony between at least two cardiac chambers or within a cardiac chamber, which alters the patient's cardiac ejection profile from a pretreatment cardiac ejection profile. This has the effect of reducing the patient's blood pressure from the measured pretreatment blood pressure.

    摘要翻译： 一种电刺激心肌以改变心脏的射血分布，控制心脏的机械功能并降低观察到的患者血压的方法。 该治疗可以由与起搏器相似的装置相关联的可植入血压传感器来调用。 在一些情况下，在测量的预处理血压超过治疗阈值的情况下，可以以相对于患者的心脏射血周期计时的电刺激来刺激患者的心脏。 这是为了在至少两个心室之间或在心室内引起不同步，其改变患者的心脏射血分布从预处理的心脏射血分布。 这具有从测量的预处理血压降低患者的血压的效果。

    Implantable Device For Promoting Repair Of A Body Lumen
    8.
    发明申请
    Implantable Device For Promoting Repair Of A Body Lumen 审中-公开
    用于促进身体内腔修复的植入式装置

    公开(公告)号：US20090210050A1

    公开(公告)日：2009-08-20

    申请号：US12429803

    申请日：2009-04-24

    申请人： Robert A. Van Tassel ,  David R. Holmes, JR. ,  Robert S. Schwartz

    发明人： Robert A. Van Tassel ,  David R. Holmes, JR. ,  Robert S. Schwartz

    IPC分类号： A61F2/06

    CPC分类号： A61F2/82 ,  A61B5/0031 ,  A61B5/028 ,  A61B5/6862 ,  A61B5/6876 ,  A61F2/0077 ,  A61F2/91 ,  A61L31/14

    摘要： An implantable stent having surface features adapted to promote an organized growth pattern of infiltrating cells when implanted in a tubular organ is provided. The surface features comprise depressions, pores, projections, pleats, channels or grooves in the stent body and are designed to increase turbulence or stagnation in the flow of a liquid, such as blood through the stent, and/or to promote the growth of infiltrating cells in an organized pattern. Alternatively, the invention stent can be populated with living cells prior to implant and can be heatable from an external source of energy, thereby inducing production of therapeutic bioactive agents from ingrowing cells. The invention also provides an implantable heatable stent for transcutaneously monitoring the flow of fluid through a lumen into which the stent is implanted by measuring the rate at which the heated stent cools in response to blood flow when the source of heat is removed.

    摘要翻译： 提供了一种植入式支架，其具有适于在植入管状器官时促进浸润细胞的有组织生长模式的表面特征。 表面特征包括支架主体中的凹陷，孔，突起，褶皱，通道或凹槽，并且被设计成增加液体如血液通过支架的流动中的湍流或停滞，和/或促进渗透的生长 细胞以有组织的模式。 或者，本发明支架可以在植入之前填充活细胞，并且可以从外部能量源加热，从而从向内生长细胞诱导治疗性生物活性剂的产生。 本发明还提供了一种可植入的可加热支架，用于通过测量当热源移除时响应于血液流动而被加热的支架冷却的速率，通过测量支架植入其中的内腔来经皮监测流体的流动。

    Self-sealing vascular access device
    9.
    发明授权
    Self-sealing vascular access device 失效
    自密封血管通路装置

    公开(公告)号：US5728132A

    公开(公告)日：1998-03-17

    申请号：US629022

    申请日：1996-04-08

    申请人： Robert A. Van Tassel ,  David R. Holmes ,  Robert S. Schwartz

    发明人： Robert A. Van Tassel ,  David R. Holmes ,  Robert S. Schwartz

    IPC分类号： A61B17/00 ,  A61B17/34 ,  A61M25/08 ,  A61B17/04

    CPC分类号： A61B17/3417 ,  A61B17/0057 ,  A61B17/00491 ,  A61B17/3498

    摘要： An instrument for achieving rapid hemostasis at the conclusion of a catheterization procedure comprises a device for injecting a fluid hemostatic agent into a puncture wound that is operatively associated with a conventional introducer sheath component of the introducer used to gain access to a blood vessel using the Seldinger technique. The hemostatic agent injection device includes a tubular member that can be concentrically disposed with a tubular introducer sheath so as to be slidable therealong and where the injection device includes a hemostatic agent inlet port at a proximal end thereof and an ejection port at a distal end, the two ports being interconnected by a lumen. In a first embodiment, the hemostatic agent injection device is adapted to coaxially surround the introducer sheath and in an alternate embodiment, the injection device is coaxially disposed within the lumen of the introducer sheath.

    摘要翻译： 用于在导管插入术结束时实现快速止血的仪器包括用于将流体止血剂注射到穿刺伤口中的装置，所述穿刺伤口与用于使用所述Seldinger进入血管的导引器的常规导引器鞘部件可操作地相关联 技术。 止血剂注射装置包括管状构件，该管状构件可以同心地设置有管状导引鞘，以便能够沿着其滑动，并且其中注射装置包括其近端处的止血剂入口和远端的排出口， 两个端口由管腔相互连接。 在第一实施例中，止血剂注射装置适于同轴地包围导引鞘，并且在替代实施例中，注射装置同轴地设置在导引鞘的内腔中。