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1.发明申请Use Of Purified 2'-Fucosyllactose, 3-Fucosyllactose and Lactodifucotetraose as Prebiotics 有权使用纯化的2'-岩藻糖基乳糖，3-岩藻糖基乳糖和乳糖四糖作为益生元公开(公告)号：US20120294840A1
公开(公告)日：2012-11-22
申请号：US13469499
申请日：2012-05-11
IPC分类号： A61K31/702 , A61K35/74 , A61P1/00 , C07H3/06
CPC分类号： A61K31/702 , A23L2/52 , A23L33/10 , A23L33/21 , A23L33/28 , A23L33/40 , A23V2002/00 , C07H3/06 , Y02A50/473 , Y02A50/481
摘要： The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
摘要翻译： 本发明提供了利用合成人乳寡糖作为益生元的组合物和方法。
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2.发明申请Use of Secretor, Lewis and Sialyl Antigen Levels in Clinical Samples as Predictors of Risk for Disease 有权在临床样本中使用分泌者，Lewis和唾液酸抗原水平作为疾病风险的预测因子公开(公告)号：US20090191551A1
公开(公告)日：2009-07-30
申请号：US12205089
申请日：2008-09-05
CPC分类号： A61K31/7028 , A61K31/702 , A61K31/715 , A61K35/741 , A61K35/745 , A61K35/747 , A61K36/06 , A61K38/02 , A61K45/06 , G01N33/6893 , G01N33/80 , G01N2800/067 , Y02A50/471 , Y02A50/473 , Y02A50/491 , Y02A50/52
摘要： An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).
摘要翻译： 可以通过测量来自个体的生物样品中的至少一种分泌型抗原的水平来鉴定坏死性小肠结肠炎和相关疾病风险的个体，并将所测量的至少一种分泌型抗原的水平与预定值或预定范围进行比较 的价值观。 可以测量的分泌抗原是：H-1，H-2，Lewisb和Lewisy抗原及其衍生物（例如，路易斯a的唾液酸化形式，路易斯x，路易斯b，路易斯y; H-1，H -2，Lewis a，Lewis x，Lewis b或Lewis y）。
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公开(公告)号：US08314061B2
公开(公告)日：2012-11-20
申请号：US12160335
申请日：2007-01-09
IPC分类号： C07K14/00
CPC分类号： A61K38/2264 , A23L33/19 , A23L33/40 , G01N2800/042 , G01N2800/044 , G01N2800/065 , G01N2800/067 , G01N2800/32 , G01N2800/321 , G01N2800/323 , G01N2800/324 , A61K2300/00
摘要： Methods for treating various disorders by orally administering adiponectin or a biologically active fragment thereof are described.
摘要翻译： 描述了通过口服施用脂联素或其生物活性片段治疗各种疾病的方法。
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4.发明授权
公开(公告)号：US5505955A
公开(公告)日：1996-04-09
申请号：US378865
申请日：1995-01-23
IPC分类号： A23L1/305 , A61K35/20 , A61K35/55 , A61K38/00 , A61K38/17 , C07K14/47 , A61K45/00 , A61K9/68
CPC分类号： C07K14/47 , A23L33/19 , A61K35/20 , A61K35/55 , A61K38/1709 , Y10S514/867 , Y10S514/904 , Y10S514/905 , Y10S514/937 , Y10S514/962
摘要： An anti-diarrheic product comprises a foodstuff and an anti-rotaviral agent such as human defatted fat globule membranes, the human milk macromolecular fraction, the milk mucin complex, the 46 Kd apparent MW glycoprotein, a polypeptide having the rotavirus-binding specificity of the 46 Kd apparent MW HMFG glycoprotein, mixtures thereof, or mixtures thereof, and optionally skim milk, curd, and/or whey. They product of the invention is provided also as an anti-diarrheal kit, with instructions for its use. The product of the invention has therapeutic and prophylactic application for inhibiting the onset of, or countering, rotavirus infection and/or diarrhea, in a subject, such as for example, infants and children (infantile gasteroenteritis), travellers, and immunodeficient persons, including HIV positive and transplant patients.
摘要翻译： 抗腹泻产品包括食品和抗旋转病毒剂如人脱脂脂肪球膜，人乳大分子级分，乳粘蛋白复合物，46Kd表观MW糖蛋白，具有轮状病毒结合特异性的多肽 46Kd表观MW HMFG糖蛋白，其混合物，或其混合物，以及任选的脱脂乳，凝乳和/或乳清。 本发明的产品也作为抗腹泻试剂盒提供，其使用说明书。 本发明的产品具有治疗和预防性应用，用于抑制受试者例如婴儿和儿童（婴儿胃脚炎），旅行者和免疫缺陷患者的轮状病毒感染和/或腹泻的发作或抵抗，包括 HIV阳性和移植患者。
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公开(公告)号：US20170354594A1
公开(公告)日：2017-12-14
申请号：US15526310
申请日：2015-11-19
申请人： Marc L. Berger , David S. Newburg
发明人： Marc L. Berger , David S. Newburg
CPC分类号： A61K9/0056 , A23G3/366 , A23G3/54 , A23L29/06 , A23V2002/00 , A61K38/47 , A61K38/4826 , A61K38/4873 , A61K38/4886 , A61K38/54 , A61K47/26 , C12Y302/01001 , C12Y302/01002 , C12Y302/01003 , C12Y302/0101 , C12Y302/0102 , C12Y302/01023 , C12Y302/01024 , C12Y302/01025 , C12Y302/01026 , C12Y302/01048 , C12Y302/0105 , C12Y302/01051 , C12Y304/21004 , C12Y304/22033 , C12Y304/24003
摘要： Provided herein are edible compositions for reducing semen viscosity and/or enhancing semen flavor, and methods of using and preparing such compositions.
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公开(公告)号：US08574850B2
公开(公告)日：2013-11-05
申请号：US13006795
申请日：2011-01-14
IPC分类号： G01N33/53
CPC分类号： A61K31/7028 , A61K31/702 , A61K31/715 , A61K35/741 , A61K35/745 , A61K35/747 , A61K36/06 , A61K38/02 , A61K45/06 , G01N33/6893 , G01N33/80 , G01N2800/067 , Y02A50/471 , Y02A50/473 , Y02A50/491 , Y02A50/52
摘要： An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).
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公开(公告)号：US20100279308A1
公开(公告)日：2010-11-04
申请号：US12719511
申请日：2010-03-08
CPC分类号： G01N33/558 , G01N33/5308 , G01N2333/42 , G01N2333/4724 , G01N2400/12
摘要： A glycan-detecting device containing a sample pad, a membrane in communication with the sample pad, a labeled lectin, an immobilized lectin of the same type, and an immobilized antibody specific to the lectin.
摘要翻译： 含有样品垫的聚糖检测装置，与样品垫连通的膜，标记的凝集素，相同类型的固定化凝集素和对凝集素特异性的固定化抗体。
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公开(公告)号：US09034847B2
公开(公告)日：2015-05-19
申请号：US13382323
申请日：2010-07-02
IPC分类号： A61K31/702 , A61K47/48 , A61P31/00 , A61P31/04 , A61P1/00 , A61P1/04 , A61P1/12 , A61P29/00 , A61K35/20
CPC分类号： A61K31/7016 , A61K31/702 , A61K35/20 , A61K47/50 , A61K47/61 , A61K47/62
摘要： A method of inhibiting inflammation in a subject comprising the administration of milk oligosaccharides or glycoconjugates containing milk oligosaccharides is disclosed.
摘要翻译： 公开了一种抑制受试者炎症的方法，包括给予含有乳寡糖的乳寡糖或糖缀合物。
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9.发明申请OLIGOSACCHARIDE COMPOSITIONS AND USE THEREOF IN THE TREATMENT OF INFECTION 审中-公开低密度脂蛋白组合物及其在感染治疗中的应用公开(公告)号：US20110207659A1
公开(公告)日：2011-08-25
申请号：US13032568
申请日：2011-02-22
IPC分类号： A61K38/16 , C12N9/20 , C12N1/19 , C07H21/04 , A61P31/04 , A61K31/715 , C12N9/36 , C12N9/08 , C12N9/26
CPC分类号： A61K31/702 , A23L33/17 , A23L33/40 , A23V2002/00 , A61K35/20 , A61K38/00 , A61K45/06 , Y02A50/47 , Y02A50/475 , A23V2200/324 , A23V2250/28 , A23V2250/54
摘要： Oligosaccharides and oligosaccharides linked to backbones such as proteins, methods for making such oligosaccharides and methods for using them to treat and/or prevent various disorders are described.
摘要翻译： 描述了与骨架如蛋白质连接的寡糖和寡糖，制备这种寡糖的方法以及用于治疗和/或预防各种疾病的方法。
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公开(公告)号：US20120202753A1
公开(公告)日：2012-08-09
申请号：US13382323
申请日：2010-07-02
IPC分类号： A61K31/7016 , A61K31/702 , A61P29/00 , A61K38/14
CPC分类号： A61K31/7016 , A61K31/702 , A61K35/20 , A61K47/50 , A61K47/61 , A61K47/62
摘要： A method of inhibiting inflammation in a subject comprising the administration of milk oligosaccharides or glycoconjugates containing milk oligosaccharides is disclosed.
摘要翻译： 公开了一种抑制受试者炎症的方法，包括给予含有乳寡糖的乳寡糖或糖缀合物。
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