Stable carotenoid emulsions suitable for parenteral administration
    2.
    发明授权
    Stable carotenoid emulsions suitable for parenteral administration 失效
    稳定的类胡萝卜素乳剂适用于肠胃外给药

    公开(公告)号:US5925684A

    公开(公告)日:1999-07-20

    申请号:US813977

    申请日:1997-03-10

    摘要: A stable oil-in-water emulsion suitable for parenteral administration, containing less than 10% by weight lecithin, consisting of an aqueous phase and of an oil phase which is very finely dispersed by means of a physiologically tolerated emulsifier and which contains at least one carotenoid and is based on a physiologically tolerated oil or fat and comprises as emulsifier polyoxyethylene/polyoxypropylene block polymers and/or lecithin, and wherein the carotenoid is present in the oil phase in a concentration above the saturation solubility of the carotenoid in the oil or fat at room temperature.

    摘要翻译: 适用于胃肠外给药的稳定的水包油乳剂,其含有小于10重量%的卵磷脂,由水相和油相组成,油相通过生理耐受性乳化剂非常细微地分散,并含有至少一种 类胡萝卜素,并且基于生理上耐受的油或脂肪,并且包含作为乳化剂聚氧乙烯/聚氧丙烯嵌段聚合物和/或卵磷脂的乳化剂,并且其中类胡萝卜素以高于类胡萝卜素在油或脂肪中的饱和溶解度的浓度存在于油相中 在室温下。