-
1.发明授权Synthetic intermediate of 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)cytosine, synthetic intermediate of thionucleoside, and method for producing the same 有权1-（2-脱氧-2-氟-4-硫代 - 乙酰-D-阿拉伯呋喃糖基）胞嘧啶的合成中间体，硫代核苷的合成中间体及其制备方法公开(公告)号：US09221865B2
公开(公告)日：2015-12-29
申请号：US14621119
申请日：2015-02-12
Applicant: FUJIFILM Corporation
Inventor： Kouki Nakamura , Satoshi Shimamura , Junichi Imoto , Motomasa Takahashi , Katsuyuki Watanabe , Kenji Wada , Yuuta Fujino , Takuya Matsumoto , Makoto Takahashi , Hideki Okada , Takehiro Yamane , Takayuki Ito
IPC: C07D409/04 , C07H19/06 , A61K31/7068 , C07C303/28 , C07C45/00 , C07B53/00 , C07C309/73 , C07C249/04 , C07C251/38 , C07H13/04 , C07H13/08 , C07H15/04 , C07H15/18 , C07H15/203 , C07H17/02 , C07H19/067 , C07H19/073 , C07H23/00 , C07C69/78 , C07H1/00 , C07H7/04 , C07C67/29 , C07C68/06 , C07C69/28 , C07C69/618 , C07C69/76 , C07C69/92 , C07C69/96
CPC classification number: C07D333/32 , A61K31/7068 , C07B53/00 , C07C45/00 , C07C47/277 , C07C67/29 , C07C68/06 , C07C69/28 , C07C69/618 , C07C69/76 , C07C69/78 , C07C69/92 , C07C69/96 , C07C249/04 , C07C251/38 , C07C251/40 , C07C303/28 , C07C309/66 , C07C309/73 , C07F7/1804 , C07H1/00 , C07H7/04 , C07H13/04 , C07H13/08 , C07H15/04 , C07H15/18 , C07H15/203 , C07H17/02 , C07H19/06 , C07H19/067 , C07H19/073 , C07H23/00 , Y02P20/55
Abstract: A compound represented by a formula [1D] as shown below (wherein R1A, R1B, R2A, R2B, R3A and R3B represent a hydrogen atom, an optionally substituted C1-6 alkyl group, and the like) is useful as an intermediate for producing a thionucleoside, and the production method of the present invention is useful as a method for producing a thionucleoside.
Abstract translation: 由下式（其中R1A，R1B，R2A，R2B，R3A和R3B表示氢原子，任选取代的C 1-6烷基等）表示的由式[1D]表示的化合物可用作生产中间体 硫代核苷，本发明的制造方法可用作硫代核苷的制造方法。
-
公开(公告)号：US10093645B2
公开(公告)日：2018-10-09
申请号：US15246177
申请日：2016-08-24
Applicant: FUJIFILM Corporation
Inventor： Kouki Nakamura , Satoshi Shimamura , Junichi Imoto , Motomasa Takahashi , Katsuyuki Watanabe , Kenji Wada , Yuuta Fujino , Takuya Matsumoto , Makoto Takahashi , Hideki Okada , Takehiro Yamane , Takayuki Ito
IPC: C07C47/277 , C07D333/32 , A61K31/7068 , C07C303/28 , C07C45/00 , C07B53/00 , C07C309/73 , C07H19/06 , C07C249/04 , C07C251/38 , C07H13/04 , C07H13/08 , C07H15/04 , C07H15/18 , C07H15/203 , C07H17/02 , C07H19/067 , C07H19/073 , C07H23/00 , C07C69/78 , C07H1/00 , C07H7/04 , C07C67/29 , C07C68/06 , C07C69/28 , C07C69/618 , C07C69/76 , C07C69/92 , C07C69/96 , C07C251/40 , C07C309/66 , C07F7/18
Abstract: A compound represented by a formula [1D] as shown below (wherein R1A, R1B, R2A, R2B, R3A and R3B represent a hydrogen atom, an optionally substituted C1-6 alkyl group, and the like) is useful as an intermediate for producing a thionucleoside, and the production method of the present invention is useful as a method for producing a thionucleoside.
-
3.发明授权Synthetic intermediate of 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl) cytosine, synthetic intermediate of thionucleoside, and method for producing the same 有权1-（2-脱氧-2-氟-4-硫代-β-D-阿拉伯呋喃糖基）胞嘧啶，硫代核苷的合成中间体及其制备方法的合成中间体公开(公告)号：US09475835B2
公开(公告)日：2016-10-25
申请号：US14873966
申请日：2015-10-02
Applicant: FUJIFILM Corporation
Inventor： Kouki Nakamura , Satoshi Shimamura , Junichi Imoto , Motomasa Takahashi , Katsuyuki Watanabe , Kenji Wada , Yuuta Fujino , Takuya Matsumoto , Makoto Takahashi , Hideki Okada , Takehiro Yamane , Takayuki Ito
IPC: C07D333/26 , C07D333/28 , C07D333/32 , C07H19/06 , A61K31/7068 , C07C303/28 , C07C45/00 , C07B53/00 , C07C309/73 , C07C249/04 , C07C251/38 , C07H13/04 , C07H13/08 , C07H15/04 , C07H15/18 , C07H15/203 , C07H17/02 , C07H19/067 , C07H19/073 , C07H23/00 , C07C69/78 , C07H1/00 , C07H7/04 , C07C67/29 , C07C68/06 , C07C69/28 , C07C69/618 , C07C69/76 , C07C69/92 , C07C69/96
CPC classification number: C07D333/32 , A61K31/7068 , C07B53/00 , C07C45/00 , C07C47/277 , C07C67/29 , C07C68/06 , C07C69/28 , C07C69/618 , C07C69/76 , C07C69/78 , C07C69/92 , C07C69/96 , C07C249/04 , C07C251/38 , C07C251/40 , C07C303/28 , C07C309/66 , C07C309/73 , C07F7/1804 , C07H1/00 , C07H7/04 , C07H13/04 , C07H13/08 , C07H15/04 , C07H15/18 , C07H15/203 , C07H17/02 , C07H19/06 , C07H19/067 , C07H19/073 , C07H23/00 , Y02P20/55
Abstract: A compound represented by a formula [1D] as shown below (wherein R1A, R1B, R2A, R2B, R3A and R3B represent a hydrogen atom, an optionally substituted C1-6 alkyl group, and the like) is useful as an intermediate for producing a thionucleoside, and the production method of the present invention is useful as a method for producing a thionucleoside.
-
公开(公告)号：US10941307B2
公开(公告)日：2021-03-09
申请号：US15967603
申请日：2018-05-01
Applicant: FUJIFILM CORPORATION
Inventor： Hiroaki Tsuyama , Kazuhiro Yokoi , Kouki Nakamura , Kenjiro Araki
Abstract: A photopolymerization initiator which is a compound having a structure in which one or more carbonyl groups that link to a carbon atom are further directly bonded to an aromatic ring of an aromatic acyl group that bonds to a phosphorus atom in an acylphosphine oxide structure. A producing method of a photopolymerization initiator produces the photopolymerization initiator. In a polymerizable composition and an ink jet recording method, the photopolymerization initiator is used. Furthermore, an acylphosphine oxide compound has a partial structure represented by Formula 1 or Formula 2.
-
Patent Agency Ranking
公开(公告)号：US10570112B2
公开(公告)日：2020-02-25
申请号：US16045047
申请日：2018-07-25
Applicant: FUJIFILM Corporation
Inventor： Kouki Nakamura , Satoshi Shimamura , Junichi Imoto , Motomasa Takahashi , Katsuyuki Watanabe , Kenji Wada , Yuuta Fujino , Takuya Matsumoto , Makoto Takahashi , Hideki Okada , Takehiro Yamane , Takayuki Ito
IPC: C07C47/277 , C07D333/32 , C07F7/18 , C07C67/29 , C07C68/06 , C07C69/28 , C07C69/618 , C07C69/76 , C07C69/92 , C07C69/96 , A61K31/7068 , C07C303/28 , C07C45/00 , C07B53/00 , C07C309/73 , C07C249/04 , C07C251/38 , C07H13/04 , C07H13/08 , C07H15/04 , C07H15/18 , C07H15/203 , C07H17/02 , C07H19/067 , C07H19/073 , C07H23/00 , C07H19/06 , C07C69/78 , C07H1/00 , C07H7/04 , C07C251/40 , C07C309/66
Abstract: A compound represented by a formula [1D] as shown below (wherein R1A, R1B, R2A, R2B, R3A and R3B represent a hydrogen atom, an optionally substituted C1-6 alkyl group, and the like) is useful as an intermediate for producing a thionucleoside, and the production method of the present invention is useful as a method for producing a thionucleoside.
-
公开(公告)号：US09187514B2
公开(公告)日：2015-11-17
申请号：US14621119
申请日：2015-02-12
Applicant: FUJIFILM Corporation
Inventor： Kouki Nakamura , Satoshi Shimamura , Junichi Imoto , Motomasa Takahashi , Katsuyuki Watanabe , Kenji Wada , Yuuta Fujino , Takuya Matsumoto , Makoto Takahashi , Hideki Okada , Takehiro Yamane , Takayuki Ito
IPC: C07D409/04 , C07H19/06 , A61K31/7068 , C07C303/28 , C07C45/00 , C07B53/00 , C07C309/73 , C07C249/04 , C07C251/38 , C07H13/04 , C07H13/08 , C07H15/04 , C07H15/18 , C07H15/203 , C07H17/02 , C07H19/067 , C07H19/073 , C07H23/00 , C07C69/78 , C07H1/00 , C07H7/04 , C07C67/29 , C07C68/06 , C07C69/28 , C07C69/618 , C07C69/76 , C07C69/92 , C07C69/96
Abstract: A compound represented by a formula [1D] as shown below (wherein R1A, R1B, R2A, R2B, R3A and R3B represent a hydrogen atom, an optionally substituted C1-6 alkyl group, and the like) is useful as an intermediate for producing a thionucleoside, and the production method of the present invention is useful as a method for producing a thionucleoside.
-
![Pyrazino[2,3-D]isoxazole derivative which is useful as a production intermediate of pyrazine carboxamide derivative](/abs-image/US/2014/12/02/US08901302B2/abs.jpg.150x150.jpg)
7.发明授权Pyrazino[2,3-D]isoxazole derivative which is useful as a production intermediate of pyrazine carboxamide derivative 有权吡嗪并[2,3-D]异恶唑衍生物，其可用作吡嗪甲酰胺衍生物的生产中间体公开(公告)号：US08901302B2
公开(公告)日：2014-12-02
申请号：US13886483
申请日：2013-05-03
Applicant: FUJIFILM Corporation , Toyama Chemical Co., Ltd.
Inventor： Kouki Nakamura , Takeshi Murakami , Hiroyuki Naitou , Naoyuki Hanaki , Katsuyuki Watanabe
IPC: C07D241/50 , C07C239/18 , C07D498/04 , C07C251/38 , C07C255/23 , C07C237/06 , C07D261/18 , C07C255/29 , C07D241/18 , C07D241/24
CPC classification number: C07D241/24 , C07C237/06 , C07C239/18 , C07C251/38 , C07C255/23 , C07C255/29 , C07D241/18 , C07D261/18 , C07D498/04
Abstract: The object of the present invention is to provide a compound which is useful as a production intermediate of pyrazine carboxamide derivative such as 6-fluoro-3-hydroxy-2-pyrazine carboxamide. The present invention provides a pyrazino[2,3-d]isoxazole derivative represented by the formula (I): wherein X represents a halogen atom, a hydroxyl group or a sulfamoyloxy group, and Y represents —C(═O)R or —CN; wherein R represents a hydrogen atom, an alkoxy group an aryloxy group, an alkyl group, an aryl group or an amino group.
Abstract translation: 本发明的目的是提供一种可用作吡嗪甲酰胺衍生物如6-氟-3-羟基-2-吡嗪甲酰胺的制备中间体的化合物。 本发明提供由式（I）表示的吡嗪并[2,3-d]异恶唑衍生物：其中X表示卤素原子，羟基或氨磺酰氧基，Y表示-C（= O）R或 - CN; 其中R表示氢原子，烷氧基，芳氧基，烷基，芳基或氨基。
-
公开(公告)号：US11898046B2
公开(公告)日：2024-02-13
申请号：US17159410
申请日：2021-01-27
Applicant: FUJIFILM CORPORATION
Inventor： Hiroaki Tsuyama , Kazuhiro Yokoi , Kouki Nakamura , Kenjiro Araki
CPC classification number: C09D11/38 , B41M5/00 , B41M7/0081 , C07F9/53 , C07F9/5337 , C08F2/50
Abstract: A photopolymerization initiator which is a compound having a structure in which one or more carbonyl groups that link to a carbon atom are further directly bonded to an aromatic ring of an aromatic acyl group that bonds to a phosphorus atom in an acylphosphine oxide structure. A producing method of a photopolymerization initiator produces the photopolymerization initiator. In a polymerizable composition and an ink jet recording method, the photopolymerization initiator is used. Furthermore, an acylphosphine oxide compound has a partial structure represented by Formula 1 or Formula 2.
-
![Substituted pyrazino[2,3-d]isooxazoles as intermediates for the synthesis of substituted pyrazinecarbonitriles and substituted pyrazinecarboxamides](/abs-image/US/2015/11/10/US09181203B2/abs.jpg.150x150.jpg)
9.发明授权Substituted pyrazino[2,3-d]isooxazoles as intermediates for the synthesis of substituted pyrazinecarbonitriles and substituted pyrazinecarboxamides 有权取代的吡嗪并[2,3-d]异恶唑作为合成取代的吡嗪甲腈和取代的吡嗪甲酰胺的中间体公开(公告)号：US09181203B2
公开(公告)日：2015-11-10
申请号：US14527174
申请日：2014-10-29
Applicant: FUJIFILM Corporation , TOYAMA CHEMICAL CO., LTD.
Inventor： Kouki Nakamura , Takeshi Murakami , Hiroyuki Naitou , Naoyuki Hanaki , Katsuyuki Watanabe
IPC: C07D241/18 , C07D241/24 , C07D261/18 , C07D498/04 , C07C239/18 , C07C237/06 , C07C251/38 , C07C255/23 , C07C255/29
CPC classification number: C07D241/24 , C07C237/06 , C07C239/18 , C07C251/38 , C07C255/23 , C07C255/29 , C07D241/18 , C07D261/18 , C07D498/04
Abstract: The object of the present invention is to provide a compound which is useful as a production intermediate of pyrazine carboxamide derivative such as 6-fluoro-3-hydroxy-2-pyrazine carboxamide. The present invention provides a pyrazino[2,3-d]isoxazole derivative represented by the formula (I): wherein X represents a halogen atom, a hydroxyl group or a sulfamoyloxy group, and Y represents —C(═O)R or —CN; wherein R represents a hydrogen atom, an alkoxy group an aryloxy group, an alkyl group, an aryl group or an amino group.
Abstract translation: 本发明的目的是提供一种可用作吡嗪甲酰胺衍生物如6-氟-3-羟基-2-吡嗪甲酰胺的制备中间体的化合物。 本发明提供由式（I）表示的吡嗪并[2,3-d]异恶唑衍生物：其中X表示卤素原子，羟基或氨磺酰氧基，Y表示-C（= O）R或 - CN; 其中R表示氢原子，烷氧基，芳氧基，烷基，芳基或氨基。
-
-
-
-
-
-
-
-
Search Results
9
records
(took 0.025 seconds)
