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    CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF
    2.
    发明公开
    CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF 审中-公开

    公开(公告)号：US20230295202A1

    公开(公告)日：2023-09-21

    申请号：US18296151

    申请日：2023-04-05

    Applicant: FUJIFILM Corporation

    Inventor： Hidenobu KUNIYOSHI ,  Takehiro Yamane ,  Takayuki Yamakawa ,  Shintaro Tanabe ,  Hideyasu Fujiwara ,  Eiichi Kodama

    IPC: C07F9/6561 ,  A61K31/683 ,  A61P31/20

    CPC classification number: C07F9/65616 ,  A61K31/683 ,  A61P31/20

    Abstract: An object of the present invention is to provide a compound exhibiting an excellent drug efficacy as an anti-adenoviral agent, and an anti-adenoviral agent. The present invention provides a compound represented by General Formula [1]
    (in the formula, R1 represents a halogen atom, an amino group which may be substituted, a C1-6 alkoxy group which may be substituted, a hydroxyl group which may be protected, or the like; R2 represents a hydrogen atom or an amino protecting group; R3 represents a C1-20 alkoxy group which may be substituted, an aryloxy group which may be substituted, an amino group which may be substituted, or the like; R4 represents a C1-20 alkoxy group which may be substituted, an aryloxy group which may be substituted, an amino group which may be substituted, or the like); or a salt thereof.

    CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF
    3.
    发明申请
    CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF 有权

    公开(公告)号：US20210147456A1

    公开(公告)日：2021-05-20

    申请号：US17158520

    申请日：2021-01-26

    Applicant: FUJIFILM Corporation

    Inventor： Hidenobu KUNIYOSHI ,  Takehiro Yamane ,  Takayuki Yamakawa ,  Shintaro Tanabe ,  Hideyasu Fujiwara ,  Eiichi Kodama

    IPC: C07F9/6561

    Abstract: An object of the present invention is to provide a compound exhibiting an excellent drug efficacy as an anti-adenoviral agent, and an anti-adenoviral agent. The present invention provides a compound represented by General Formula [1] (in the formula, R1 represents a halogen atom, an amino group which may be substituted, a C1-6 alkoxy group which may be substituted, a hydroxyl group which may be protected, or the like; R2 represents a hydrogen atom or an amino protecting group; R3 represents a C1-20 alkoxy group which may be substituted, an aryloxy group which may be substituted, an amino group which may be substituted, or the like; R4 represents a C1-20 alkoxy group which may be substituted, an aryloxy group which may be substituted, an amino group which may be substituted, or the like); or a salt thereof.

    Cyclobutyl purine derivative or salt thereof
    4.
    发明授权
    Cyclobutyl purine derivative or salt thereof 有权

    公开(公告)号：US12202850B2

    公开(公告)日：2025-01-21

    申请号：US18296151

    申请日：2023-04-05

    Applicant: FUJIFILM Corporation

    Inventor： Hidenobu Kuniyoshi ,  Takehiro Yamane ,  Takayuki Yamakawa ,  Shintaro Tanabe ,  Hideyasu Fujiwara ,  Eiichi Kodama

    IPC: A61K31/683 ,  A61P31/20 ,  C07F9/6561

    Abstract: An object of the present invention is to provide a compound exhibiting an excellent drug efficacy as an anti-adenoviral agent, and an anti-adenoviral agent. The present invention provides a compound represented by General Formula [1] (in the formula, R1 represents a halogen atom, an amino group which may be substituted, a C1-6 alkoxy group which may be substituted, a hydroxyl group which may be protected, or the like; R2 represents a hydrogen atom or an amino protecting group; R3 represents a C1-20 alkoxy group which may be substituted, an aryloxy group which may be substituted, an amino group which may be substituted, or the like; R4 represents a C1-20 alkoxy group which may be substituted, an aryloxy group which may be substituted, an amino group which may be substituted, or the like); or a salt thereof.

    CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF
    8.
    发明申请
    CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF 有权

    公开(公告)号：US20210155644A1

    公开(公告)日：2021-05-27

    申请号：US17158547

    申请日：2021-01-26

    Applicant: Fujifilm Corporation

    Inventor： Hidenobu Kuniyoshi ,  Takehiro Yamane ,  Takayuki Yamakawa ,  Hideyasu Fujiwara ,  Eiichi Kodama

    IPC: C07F9/6561 ,  A61P31/20 ,  C07F9/6574

    Abstract: An object of the present invention is to provide a compound exhibiting an excellent drug efficacy as an anti-adenoviral agent, and an anti-adenoviral agent. The present invention provides an anti-adenoviral agent including a compound represented by General Formula [1] (in the formula, R1 represents a hydrogen atom, a halogen atom, an amino group which may be substituted, a monocyclic nitrogen-containing heterocyclic ring group which may be substituted (provided that a nitrogen atom forming the ring is bonded to a carbon atom to which R1 is bonded), a monocyclic nitrogen- and oxygen-containing heterocyclic ring group which may be substituted (provided that a nitrogen atom forming the ring is bonded to a carbon atom to which R1 is bonded), a C1-6 alkoxy group which may be substituted, a hydroxyl group which may be protected, or the like; R2 represents a hydrogen atom or an amino protecting group; R3 represents a C1-20 alkoxy group which may be substituted, an aryloxy group which may be substituted, an amino group which may be substituted, or the like; R4 represents a C1-20 alkoxy group which may be substituted, an aryloxy group which may be substituted, an amino group which may be substituted, or the like; and X represents an oxygen atom or a sulfur atom) or a salt thereof.

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