摘要:
A composition and method for inhibiting proliferation of a tumor cell compared to a non-tumor cell. Also described are methods of screening for a composition that inhibits cap-dependent translation compared to cap-independent translation of proteins.
摘要:
A composition and method for inhibiting proliferation of a tumor cell compared to a non-tumor cell. Also described are methods of screening for a composition that inhibits cap-dependent translation compared to cap-independent translation of proteins.
摘要:
Compositions and methods for inhibiting translation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, (4) disorders associated with viral infections, and/or (5) non-proliferative metabolic disorders such as type II diabetes where inhibition of translation initiation is beneficial using the compounds disclosed herein.
摘要:
Compositions and methods for inhibiting translation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, (4) disorders associated with viral infections, and/or (5) non-proliferative metabolic disorders such as type II diabetes where inhibition of translation initiation is beneficial using the compounds disclosed herein.
摘要:
A method for manufacturing a rolling-element bearing cage includes clamping a cage blank in the radial direction using a clamping element in a first position where the cage blank is processed. Then, the cage blank is rotated relative to the clamping element to a second position where the cage blank is further processed. A device for manufacturing a rolling-element bearing cage includes the clamping element, which remain stationary together with a tool for processing the cage blank, while only the cage blank is rotated.
摘要:
A bearing cage for a rolling element bearing includes a plurality of individual bearing cage segments configured to respectively accommodate rolling elements in rolling element pockets formed by the bearing cage segments. Each bearing cage segment includes a first coupling device disposed on a first axial end thereof. A first lamellar support ring defines first and second ring halves that are connected to each other, are axially adjacent to each other are biased towards each other. The first ring half extends through the respective first coupling devices of the plurality of bearing cage segments and the second ring half is disposed on an axially-inner side or an axially-outer side of the first coupling devices such that the first coupling devices are clamped between the first and second ring halves.
摘要:
(Modified) rice endosperm protein is used as novel protective hydrocolloid for active ingredients, especially fat-soluble active ingredients and/or colorants. Included are compositions comprising (modified) rice endosperm protein and at least one active ingredient and to their manufacture, as well as to the (modified) rice endosperm protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions, and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a (modified) rice endosperm protein and such a composition, respectively.
摘要:
A pressure supply to an automatic selector device of a change-speed gearbox, controls working pressure via a multi-path valve device. The working pressure is supplied either only to clutch actuators of two drive clutches located in the force path before the change-speed gearbox or to selector actuators for the actuation of selector clutches producing the force path within the change-speed gearbox. The clutch actuator of one drive clutch is subjected to a load-dependent main pressure in the latter case.
摘要:
A pressure medium actuated friction clutch with axially movable friction discs is engaged by at least one engagement spring and by an engagement actuator, and can be disengaged by a disengagement actuator In the steady-state engaged condition, only the spring force is effective.
摘要:
An arrangement for use on a vehicle, especially truck for transporting portable bridges, with the sections of a portable bridge being adapted to be arranged one above the other on support frames, and being adapted to be received on the support frames, by means of a bridge placing apparatus. The support frames are distributed over the effective length, behind the cab of the particular truck, and secured to the frame or the like thereof. The support frames are provided as independent components, releasably securable to the vehicle frame or to a loading platform, and the support frame immediately adjacent the cab is provided with a pivot drive arrangement for moving the sections of the portable bridge in the longitudinal direction of the vehicle.