Process for the purification of acarbose with polymers
    7.
    发明授权
    Process for the purification of acarbose with polymers 失效
    用聚合物净化阿卡波糖的方法

    公开(公告)号:US4767850A

    公开(公告)日:1988-08-30

    申请号:US868403

    申请日:1986-05-29

    摘要: In the purification of acarbose by contacting an acarbose-containing solution with a cation exchanger to adsorb the acarbose, eluting the ion exchanger and collecting an eluate fraction enriched in purified acarbose, the improvement wherein the cation exchanger is a polymer obtained by polymerizing an aromatic compound possessing at least one vinyl group and at least one hydrophilic monomer in the presence of a solvent for the monomer which is a precipitant for the crosslinked polymer formed, isolating the resistant polymer, and sulphonating the polymer in the presence of a swelling agent for the polymer. The invention gives sharp separation and other processing advantages.

    摘要翻译: 在通过使含有阿卡波糖的溶液与阳离子交换剂接触以吸附阿卡波糖以洗脱离子交换剂并收集富集纯化的阿卡波糖的洗脱液级分的阿卡波糖的纯化中,其中阳离子交换剂是通过使芳族化合物聚合而获得的聚合物 在用于形成的交联聚合物的沉淀剂的溶剂的溶剂存在下,具有至少一个乙烯基和至少一个亲水性单体,分离耐药聚合物,并在聚合物溶胀剂存在下磺化聚合物 。 本发明提供了清晰的分离等加工优点。