Metallic object with a thin polyphase oxide coating and process for the manufacture thereof
    1.
    发明授权
    Metallic object with a thin polyphase oxide coating and process for the manufacture thereof 失效
    具有薄多环氧化物涂层的金属物体及其制造方法

    公开(公告)号:US06524718B1

    公开(公告)日:2003-02-25

    申请号:US09297220

    申请日:1999-06-21

    IPC分类号: B32B1504

    摘要: A metallic object, having a metallic substrate of a valve metal or a valve metal alloy inclusive of intermetallic phases, and a thin polyphase oxide coating, is disclosed. The polyphase oxide coating has a metal oxide phase and at least one other organic and/or inorganic phase. The polyphase oxide coating is produced by bringing the metallic substrate into contact with an organic and/or inorganic component to be integrated into the polyphase oxide coating such that the inorganic and/or organic phases are present at or in the direct vicinity of the substrate surface and by simultaneously or subsequently anodically polarizing the substrate material in an electrolytic solution.

    摘要翻译: 公开了一种金属物体,其具有阀金属的金属基底或包括金属间相的阀金属合金和薄的多相氧化物涂层。 多相氧化物涂层具有金属氧化物相和至少一种其它有机和/或无机相。 多相氧化物涂层是通过使金属基材与有机和/或无机组分接触而制成的,以将其整合到多相氧化物涂层中,使得无机和/或有机相存在于基材表面的直接附近 并且通过同时或随后在电解液中阳极极化基板材料。

    OSTEOGENIC COMPOSITE MATRIX, METHOD FOR THE PRODUCTION THEREOF AND IMPLANT AND SCAFFOLD FOR TISSUE ENGINEERING PROVIDED WITH A COATING FORMED BY SAID OSTEOGENIC COMPOSITE MATRIX
    2.
    发明申请
    OSTEOGENIC COMPOSITE MATRIX, METHOD FOR THE PRODUCTION THEREOF AND IMPLANT AND SCAFFOLD FOR TISSUE ENGINEERING PROVIDED WITH A COATING FORMED BY SAID OSTEOGENIC COMPOSITE MATRIX 有权
    软骨组合物基质,其生产方法,用于组织工程的植入物和SCAFFOLD,用由酸性复合基质形成的涂层

    公开(公告)号:US20100119575A1

    公开(公告)日:2010-05-13

    申请号:US12572884

    申请日:2009-10-02

    摘要: The invention relates to an osteogenic composite matrix consisting of collagen and non-collagen components of an extracellular matrix (ECM-components), to a method for producing said matrix, to a method for producing an implant or a scaffold for tissue engineering which is provided with a coating formed by said osteogenic composite matrix and is used for stimulating and accelerating a hard tissue formation such as, for example. The implant osseointegration in bones. The inventive osteogenic composite matrix comprises a collagen and at least one non-collagen ECM component or the derivatives thereof, wherein the collagen component consists of non-crosslinked collagen fibres produced by fibrillogenesis and the non-collagen ECM component or the derivatives thereof are integrated into said collagen fibres.

    摘要翻译: 本发明涉及由细胞外基质(ECM-组分)的胶原和非胶原组分组成的成骨复合基质,制备所述基质的方法,提供用于组织工程的植入物或支架的制备方法 具有由所述成骨复合基质形成的涂层,并且用于刺激和加速例如硬组织形成。 骨骼中的植入物骨整合。 本发明的成骨复合基质包括胶原蛋白和至少一种非胶原ECM组分或其衍生物,其中胶原组分由通过纤维发生产生的非交联胶原纤维组成,非胶原ECM组分或其衍生物被整合到 说胶原纤维。

    Osteogenic composite matrix, method for the production thereof and implant and scaffold for tissue engineering provided with a coating formed by said osteogenic composite matrix
    4.
    发明授权
    Osteogenic composite matrix, method for the production thereof and implant and scaffold for tissue engineering provided with a coating formed by said osteogenic composite matrix 有权
    成骨复合基质,其生产方法和用于组织工程的植入物和支架,其具有由所述成骨复合基质形成的涂层

    公开(公告)号:US08043627B2

    公开(公告)日:2011-10-25

    申请号:US12572884

    申请日:2009-10-02

    IPC分类号: A61K9/00 C07K14/78

    摘要: The invention relates to an osteogenic composite matrix consisting of collagen and non-collagen components of an extracellular matrix (ECM-components), to a method for producing said matrix, to a method for producing an implant or a scaffold for tissue engineering which is provided with a coating formed by said osteogenic composite matrix and is used for stimulating and accelerating a hard tissue formation such as, for example. The implant osseointegration in bones. The inventive osteogenic composite matrix comprises a collagen and at least one non-collagen ECM component or the derivatives thereof, wherein the collagen component consists of non-crosslinked collagen fibers produced by fibrillogenesis and the non-collagen ECM component or the derivatives thereof are integrated into said collagen fibers.

    摘要翻译: 本发明涉及由细胞外基质(ECM-组分)的胶原和非胶原组分组成的成骨复合基质,制备所述基质的方法,提供用于组织工程的植入物或支架的制备方法 具有由所述成骨复合基质形成的涂层,并且用于刺激和加速例如硬组织形成。 骨骼中的植入物骨整合。 本发明的成骨复合基质包括胶原蛋白和至少一种非胶原ECM组分或其衍生物,其中胶原组分由通过纤维发生产生的非交联胶原纤维组成,非胶原ECM组分或其衍生物被整合到 说胶原纤维。

    Osteogenic Composite Matrix, Method for the Production Thereof and Implant and Scaffold for Tissue Engineering Provided with a Coating Formed by Said Osteogenic Composite matrix
    8.
    发明申请
    Osteogenic Composite Matrix, Method for the Production Thereof and Implant and Scaffold for Tissue Engineering Provided with a Coating Formed by Said Osteogenic Composite matrix 审中-公开
    成骨复合基质,其生产方法和用于组织工程的植入物和支架提供由所述成骨复合基质形成的涂层

    公开(公告)号:US20070237799A1

    公开(公告)日:2007-10-11

    申请号:US11578607

    申请日:2005-04-15

    摘要: The invention relates to an osteogenic composite matrix consisting of collagen and non-collagen components of an extracellular matrix (ECM-components), to a method for producing said matrix, to a method for producing an implant or a scaffold for tissue engineering which is provided with a coating formed by said osteogenic composite matrix and is used for stimulating and accelerating a hard tissue formation such as, for example the implant osseointegration in bones. The inventive osteogenic composite matrix comprises a collagen and at least one non-collagen ECM component or the derivatives thereof, wherein the collagen component consists of non-crosslinked collagen fibres produced by fibrillogenesis and the non-collagen ECM component or the derivatives thereof are integrated into said collagen fibres.

    摘要翻译: 本发明涉及由细胞外基质(ECM-组分)的胶原和非胶原组分组成的成骨复合基质,制备所述基质的方法,提供用于组织工程的植入物或支架的制备方法 具有由所述成骨复合基质形成的涂层,并且用于刺激和加速硬组织形成,例如骨骼中的植入物骨整合。 本发明的成骨复合基质包括胶原蛋白和至少一种非胶原ECM组分或其衍生物,其中胶原组分由通过纤维发生产生的非交联胶原纤维组成,非胶原ECM组分或其衍生物被整合到 说胶原纤维。