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公开(公告)号：US20050069878A1
公开(公告)日：2005-03-31
申请号：US10481041
申请日：2002-06-12
申请人： Henry Yue , Dyung Lu , April Hafalia , Chandra Arvizu , Jayalaxmi Ramkumar , Y Tang , Farrah Khan , Barrie Greene , Thomas Richardson , Junming Yang , Craig Ison , Bridget Warren , Vicki Elliott , Brooke Emerling , Ann Gorvard , Ernestine Lee , Jennifer Griffin , Yeganeh Zebarjadian , Anita Swarnakar , Preeti Lal , Mariah Baughn , Uyen Tran , Sally Lee , Ian Forsythe , Janice Au-Young
发明人： Henry Yue , Dyung Lu , April Hafalia , Chandra Arvizu , Jayalaxmi Ramkumar , Y Tang , Farrah Khan , Barrie Greene , Thomas Richardson , Junming Yang , Craig Ison , Bridget Warren , Vicki Elliott , Brooke Emerling , Ann Gorvard , Ernestine Lee , Jennifer Griffin , Yeganeh Zebarjadian , Anita Swarnakar , Preeti Lal , Mariah Baughn , Uyen Tran , Sally Lee , Ian Forsythe , Janice Au-Young
IPC分类号： G01N33/50 , A01K67/00 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/16 , A61P3/10 , A61P7/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P15/00 , A61P15/10 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/06 , A61P21/00 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/20 , A61P25/28 , A61P27/06 , A61P27/12 , A61P29/00 , A61P31/04 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/08 , C07H21/04 , C07K1/14 , C07K14/47 , C07K14/475 , C07K16/18 , C07K16/46 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53
CPC分类号： C07K14/4702 , A01K2217/05 , A61K38/00 , C07K14/4747
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译： 本发明的各种实施方案提供与细胞生长，分化和死亡（CGDD）相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号：US20050123912A1
公开(公告)日：2005-06-09
申请号：US10486977
申请日：2002-08-14
申请人： Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
发明人： Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/16 , A61P3/10 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/00 , A61P15/00 , A61P17/00 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/00 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/22
CPC分类号： C07K14/4702 , A61K38/00 , G01N2500/00
摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。
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公开(公告)号：US20050118582A1
公开(公告)日：2005-06-02
申请号：US10483505
申请日：2002-07-10
申请人： Anita Swarnakar , Thomas Richardson , Bridget Warren , Jennifer Griffin , Y Tang , Henry Yue , Mariah Baughn , Brooke Emerling , Preeti Lal , Dyung Lu , Ian Forsythe , Jayalaxmi Ramkumar , Joana Li , Shanya Becha , Brendan Duggan , Madhusudan Sanjanwala , Ernestine Lee , Neil Burford , Vicki Elliott , Craig Ison , Li Ding , Mark Borowsky , Monique Yao , Ines Barroso , Bao Tran , Narinder Chawla , April Hafalia , Danniel Nguyen , Yan Lu , Chandra Arvizu
发明人： Anita Swarnakar , Thomas Richardson , Bridget Warren , Jennifer Griffin , Y Tang , Henry Yue , Mariah Baughn , Brooke Emerling , Preeti Lal , Dyung Lu , Ian Forsythe , Jayalaxmi Ramkumar , Joana Li , Shanya Becha , Brendan Duggan , Madhusudan Sanjanwala , Ernestine Lee , Neil Burford , Vicki Elliott , Craig Ison , Li Ding , Mark Borowsky , Monique Yao , Ines Barroso , Bao Tran , Narinder Chawla , April Hafalia , Danniel Nguyen , Yan Lu , Chandra Arvizu
CPC分类号： C07K14/4702
摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。
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公开(公告)号：US20060216706A1
公开(公告)日：2006-09-28
申请号：US10484603
申请日：2002-07-16
申请人： Y Tang , Vicki Elliott , Mariah Baughn , Henry Yue , Aaron Klammer , April Hafalia , Elizabeth Stewart , Cynthia Honchell , Ann Gorvard , Ian Forsythe , Li Ding , Uyen Tran , Jennifer Griffin , Yeganeh Zebarjadian , Anna Chinn , Anne Curtis , Mark Borowsky , Anita Swarnakar , Neil Burford , Wen Luo , Ernestine Lee , Brooke Emerling , Soo Lee , Junming Yang , Farrah Khan , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla , Brendan Duggan , Kimberly Gietzen , Karen Jones
发明人： Y Tang , Vicki Elliott , Mariah Baughn , Henry Yue , Aaron Klammer , April Hafalia , Elizabeth Stewart , Cynthia Honchell , Ann Gorvard , Ian Forsythe , Li Ding , Uyen Tran , Jennifer Griffin , Yeganeh Zebarjadian , Anna Chinn , Anne Curtis , Mark Borowsky , Anita Swarnakar , Neil Burford , Wen Luo , Ernestine Lee , Brooke Emerling , Soo Lee , Junming Yang , Farrah Khan , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla , Brendan Duggan , Kimberly Gietzen , Karen Jones
IPC分类号： C12Q1/68 , G01N33/574 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号： C07K14/47 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , G01N33/574 , G01N2510/00
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译： 本发明的各种实施方案提供与细胞生长，分化和死亡（CGDD）相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号：US20060115813A1
公开(公告)日：2006-06-01
申请号：US10480962
申请日：2002-06-06
申请人： Junming Yang , Brooke Emerling , Y Tang , Mariah Baugh , Ernestine Lee , Jayalaxmi Ramkumar , Henry Yue , Jennifer Griffin , Narinder Chawla , Bao Tran , Danniel Nguyen , Farrah Khan , Ameena Gandhi , April Hafalia , Anita Swarnakar , Rajagopal Gururajan , Jennifer Policky , Monique Yao , Bridget Warren , Kimberly Gietzen , Vicki Elliott , Soo Lee , Bharati Sanjanwala , Cynthia Honchell , Ian Forsythe , Ann Gorvad , Thomas Richardson , Sally Lee , Ines Barroso
发明人： Junming Yang , Brooke Emerling , Y Tang , Mariah Baugh , Ernestine Lee , Jayalaxmi Ramkumar , Henry Yue , Jennifer Griffin , Narinder Chawla , Bao Tran , Danniel Nguyen , Farrah Khan , Ameena Gandhi , April Hafalia , Anita Swarnakar , Rajagopal Gururajan , Jennifer Policky , Monique Yao , Bridget Warren , Kimberly Gietzen , Vicki Elliott , Soo Lee , Bharati Sanjanwala , Cynthia Honchell , Ian Forsythe , Ann Gorvad , Thomas Richardson , Sally Lee , Ines Barroso
摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译： 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与INTSIG的异常表达相关的紊乱的方法。
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公开(公告)号：US20060051836A1
公开(公告)日：2006-03-09
申请号：US10491468
申请日：2002-10-10
申请人： Y Tang , Ian Forsythe , Brooke Emerling , April Hafalia , Henry Yue , Kimberly Gietzen , Narinder Chawla , Joseph Marquis , Shanya Becha , Amy Kable , Preeti Lal , Thomas Richardson , Soo Lee , Ernestine Lee , Bao Tran
发明人： Y Tang , Ian Forsythe , Brooke Emerling , April Hafalia , Henry Yue , Kimberly Gietzen , Narinder Chawla , Joseph Marquis , Shanya Becha , Amy Kable , Preeti Lal , Thomas Richardson , Soo Lee , Ernestine Lee , Bao Tran
CPC分类号： C07K14/47
摘要： Various embodiments of the invention provide human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.
摘要翻译： 本发明的各种实施方案提供用于疾病检测和治疗（MDDT）的人分子和鉴定和编码MDDT的多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与MDDT异常表达相关的紊乱的方法。
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公开(公告)号：US20060035315A1
公开(公告)日：2006-02-16
申请号：US10203486
申请日：2001-02-23
申请人： Henry Yue , Y Tang , Preeti Lal , Jennifer Policky , Danniel Nguyen , Janice Au-Young , Monique Yao , Farrah Khan , Narinder Walia , Ameena Gandhi , Catherine Tribouley , Chandra Arvizu , Michael Thornton , Barrie Greene , Roberto Hernandez , Mark Borowsky , Madhu Sanjanwala
发明人： Henry Yue , Y Tang , Preeti Lal , Jennifer Policky , Danniel Nguyen , Janice Au-Young , Monique Yao , Farrah Khan , Narinder Walia , Ameena Gandhi , Catherine Tribouley , Chandra Arvizu , Michael Thornton , Barrie Greene , Roberto Hernandez , Mark Borowsky , Madhu Sanjanwala
IPC分类号： C07K14/705 , C07H21/04 , C12P21/06 , C12N15/74
CPC分类号： C07K14/705 , A61K38/00
摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
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公开(公告)号：US20050048479A1
公开(公告)日：2005-03-03
申请号：US10311625
申请日：2001-06-26
申请人： Ameena Gandhi , Catherine Tribouley , Li Ding , Dyung Lu , Ernestine Lee , Henry Yue , Junming Yang , Mariah Baughn , Michael Thornton , Monique Yao , Narinder Chawla , Y Tang , Vicki Elliott , Yan Lu
发明人： Ameena Gandhi , Catherine Tribouley , Li Ding , Dyung Lu , Ernestine Lee , Henry Yue , Junming Yang , Mariah Baughn , Michael Thornton , Monique Yao , Narinder Chawla , Y Tang , Vicki Elliott , Yan Lu
IPC分类号： G01N33/50 , A61K38/00 , A61K38/51 , A61K45/00 , A61P9/00 , A61P15/00 , A61P21/00 , A61P21/04 , A61P25/00 , A61P27/00 , A61P43/00 , C07K16/40 , C07K16/46 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/88 , C12N15/09 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , G01N33/573 , A01K67/00 , C07H21/04 , C12N9/22
CPC分类号： C12N9/88 , A01K2217/05 , A61K38/00 , C12Y406/01001 , C12Y406/01002
摘要： The invention provides human adenylyl and guanylyl cyclases (ADGUC) and polynucleotides which identify and encode ADGUC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ADGUC.
摘要翻译： 本发明提供鉴定和编码ADGUC的人腺苷酰和鸟苷酸环化酶（ADGUC）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与ADGUC的异常表达相关的紊乱的方法。
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公开(公告)号：US20050175607A1
公开(公告)日：2005-08-11
申请号：US10220335
申请日：2001-02-26
申请人： Y Tang , Chenghua Liu , Vinod Asundi , Chongjun Xu , Tom Wehrman , Feiyan Ren , Yunqing Ma , Ping Zhou , Qing Zha , Yonghong Yang , Radoje Drmanac , Jie Zhang , Rui-hong Chen , Jian-Rui Wang , Dunrui Wang , Aidong Xue
发明人： Y Tang , Chenghua Liu , Vinod Asundi , Chongjun Xu , Tom Wehrman , Feiyan Ren , Yunqing Ma , Ping Zhou , Qing Zha , Yonghong Yang , Radoje Drmanac , Jie Zhang , Rui-hong Chen , Jian-Rui Wang , Dunrui Wang , Aidong Xue
CPC分类号： C07K14/47 , C12Q1/6886
摘要： The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
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公开(公告)号：US20050196754A1
公开(公告)日：2005-09-08
申请号：US10450763
申请日：2001-03-30
申请人： Radoje Drmanac , Chenghua Liu , Y Tang
发明人： Radoje Drmanac , Chenghua Liu , Y Tang
IPC分类号： A61K38/00 , C07H21/04 , C07K14/47 , C07K14/81 , C12N5/02 , C12N9/00 , C12N15/12 , C12P21/06 , C12Q1/68
CPC分类号： C07K14/47 , A61K38/00 , C07K14/8107
摘要： The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
摘要翻译： 本发明提供了新的核酸，由这些核酸编码的新的多肽序列及其用途。
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