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公开(公告)号：US20190241936A1
公开(公告)日：2019-08-08
申请号：US16227735
申请日：2018-12-20
Applicant: Industrial Technology Research Institute
Inventor： Tseng-Huang Liu , Chia-Ying Tang , Pei-Shin Jiang
IPC: C12Q1/689 , C07K17/02 , C12Q1/6895 , G01N33/543
CPC classification number: C12Q1/689 , C07K17/02 , C12Q1/04 , C12Q1/37 , C12Q1/6895 , G01N33/523 , G01N33/54306
Abstract: A test strip for microorganism detection includes: a porous substrate, a surface of which a surface has a first color; and a microorganism detection composition, which is at least adhered to a part of a surface of the porous substrate or at least adhered to a part of a surface of the porous substrate and a part of an interior of the porous substrate. The microorganism detection composition includes: a plurality of colored particles having a second color different than the first color; and a plurality of specific peptides immobilized on the surfaces of the plurality of colored particles, in which the plurality of specific peptides connect the plurality of colored particles to each other to make the plurality of colored particles aggregate to cover the part of the surface of the porous substrate and present the second color on the part of the surface of the porous substrate.
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公开(公告)号：US20140186894A1
公开(公告)日：2014-07-03
申请号：US14138155
申请日：2013-12-23
Applicant: Industrial Technology Research Institute
Inventor： Tseng-Huang Liu , Pei-Shin Jiang , Chih-Lung Lin , Su-Jan Lee , Chao-Hung Kao
CPC classification number: C12N9/1252
Abstract: Isolated DNA polymerase and the mutant DNA polymerases thereof are provided. The DNA polymerases have good thermostability.
Abstract translation: 提供了分离的DNA聚合酶及其突变型DNA聚合酶。 DNA聚合酶具有良好的热稳定性。
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公开(公告)号：US20210128199A1
公开(公告)日：2021-05-06
申请号：US17145513
申请日：2021-01-11
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： CHIH-WEN YANG , Po-Jen Cheng , Ting-Hsuan Chen , Tseng-Huang Liu
Abstract: A device, an instrument and a belt for tying the cervix are provided. The device includes the belt and the instrument. The belt is used to tie the cervix. The instrument includes a first outer pipe, a second outer pipe and two fork structures. The first outer pipe and the second outer pipe are rotatable to each other. The two fork structures are connected individually to corresponding axial ends of the first outer pipe and the second outer pipe, respectively, and insert into the belt detachably.
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公开(公告)号：US20180104696A1
公开(公告)日：2018-04-19
申请号：US15588043
申请日：2017-05-05
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Tseng-Huang Liu , Kuo-Hsing Wen , Pei-Shin Jiang , Jie-Len Huang , Ting-Hsuan CHEN
CPC classification number: B01L7/52 , B01L7/525 , B01L2300/0654 , B01L2300/0681 , B01L2300/0832 , B01L2300/18 , B01L2400/0445 , C12Q1/686 , G01N21/00
Abstract: A convective polymerase chain reaction apparatus includes a tube, a temperature control unit, at least one light source and a sensor. The tube includes a cavity used to contain a reaction solution. The reaction solution has a liquid level measured from a bottom of the cavity to a top surface of the reaction solution. The temperature control unit is disposed adjacent to the tube for controlling the temperature of the reaction solution. The at least one light source provides a light beam passing through an incident portion of the tube to excite the reaction solution emitting a fluorescent light. The incident portion is located at a height greater than ½ of a liquid level. The sensor is adjacent to the tube for detecting the excited fluorescence. The light beam has an incident direction forming a non-straight angle with a long axis of the tube.
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公开(公告)号：US11648034B2
公开(公告)日：2023-05-16
申请号：US17145513
申请日：2021-01-11
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Chih-Wen Yang , Po-Jen Cheng , Ting-Hsuan Chen , Tseng-Huang Liu
CPC classification number: A61B17/44 , A61B17/12009 , A61B17/42 , A61B90/30 , A61B2017/4225
Abstract: A device, an instrument and a belt for tying the cervix are provided. The device includes the belt and the instrument. The belt is used to tie the cervix. The instrument includes a first outer pipe, a second outer pipe and two fork structures. The first outer pipe and the second outer pipe are rotatable to each other. The two fork structures are connected individually to corresponding axial ends of the first outer pipe and the second outer pipe, respectively, and insert into the belt detachably.
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Patent Agency Ranking
公开(公告)号：US10918414B2
公开(公告)日：2021-02-16
申请号：US16220221
申请日：2018-12-14
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE , Chang Gung Medical Foundation Lin-Kou Chang Gung Memorial Hospital
Inventor： Chih-Wen Yang , Po-Jen Cheng , Ting-Hsuan Chen , Tseng-Huang Liu
Abstract: A device, an instrument and a belt for tying the cervix are provided. The device includes the belt and the instrument. The belt is used to tie the cervix. The instrument includes a first outer pipe, a second outer pipe and two fork structures. The first outer pipe and the second outer pipe are rotatable to each other. The two fork structures are connected individually to corresponding axial ends of the first outer pipe and the second outer pipe, respectively, and insert into the belt detachably.
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公开(公告)号：US09505003B2
公开(公告)日：2016-11-29
申请号：US14582697
申请日：2014-12-24
Applicant: Industrial Technology Research Institute
Inventor： Chih-Hsiang Sung , Tseng-Huang Liu , Ruey-Shyan Hong , Ting-Hsuan Chen , Ping-Jung Wu , Kuo-Hsing Wen , Wan-Chi Chang
CPC classification number: B01L7/52 , B01L9/06 , B01L2200/18 , B01L2300/046 , B01L2300/0663 , B01L2300/1805 , B01L2300/1844
Abstract: A portable real-time heating and detection device includes a body, a cover and a detection unit. The body has an opening, and a base. The cover has a control unit and a fix unit. The detection unit is disposed on the base of the body and has a thermostat, an optical excitation, an optical detection, and a circuit board. The thermostat is disposed close to the opening and has at least one thermostat zone. The optical exciter is disposed between the thermostat and the base. The optical detector is disposed between the thermostat and the opening. The circuit board is electrical coupled to the control unit, the thermostat, the optical excitation, and the optical detector, respectively.
Abstract translation: 便携式实时加热和检测装置包括主体，盖和检测单元。 身体有一个开口和一个基地。 盖具有控制单元和固定单元。 检测单元设置在主体的基座上并具有恒温器，光学激励，光学检测和电路板。 恒温器靠近开口设置，并具有至少一个恒温区。 光激发器设置在恒温器和基座之间。 光学检测器设置在恒温器和开口之间。 电路板分别电耦合到控制单元，恒温器，光学激励和光学检测器。
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公开(公告)号：US11613755B2
公开(公告)日：2023-03-28
申请号：US17132793
申请日：2020-12-23
Applicant: Industrial Technology Research Institute
Inventor： Ping-Fu Cheng , Ya-Ling Chiu , Kang-Li Wang , Po-Yen Lin , Shih-Ta Chen , Tseng-Huang Liu , Pei-Shin Jiang
IPC: C12N15/115 , A61K47/54 , A61P35/00 , A61K9/00 , C12N15/113
Abstract: A nucleic acid-drug complex is provided in the present disclosure, which includes a nucleic acid sequence of an anti-PD-L1 aptamer and a CpG oligonucleotide sequence capable of activating TLR9, in which the CpG oligonucleotide sequence consists of a first fragment and a second fragment, and the nucleic acid sequence of the anti-PD-L1 aptamer is inserted between the first fragment and the second fragment.
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公开(公告)号：US20190183530A1
公开(公告)日：2019-06-20
申请号：US16220221
申请日：2018-12-14
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE , Chang Gung Medical Foundation Lin-Kou Chang Gung Memorial Hospital
Inventor： CHIH-WEN YANG , Po-Jen Cheng , Ting-Hsuan Chen , Tseng-Huang Liu
CPC classification number: A61B17/44 , A61B17/12009 , A61B2017/4225
Abstract: A device, an instrument and a belt for tying the cervix are provided. The device includes the belt and the instrument. The belt is used to tie the cervix. The instrument includes a first outer pipe, a second outer pipe and two fork structures. The first outer pipe and the second outer pipe are rotatable to each other. The two fork structures are connected individually to corresponding axial ends of the first outer pipe and the second outer pipe, respectively, and insert into the belt detachably.
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公开(公告)号：US10183295B2
公开(公告)日：2019-01-22
申请号：US15588043
申请日：2017-05-05
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Tseng-Huang Liu , Kuo-Hsing Wen , Pei-Shin Jiang , Jie-Len Huang , Ting-Hsuan Chen
Abstract: A convective polymerase chain reaction apparatus includes a tube, a temperature control unit, at least one light source and a sensor. The tube includes a cavity used to contain a reaction solution. The reaction solution has a liquid level measured from a bottom of the cavity to a top surface of the reaction solution. The temperature control unit is disposed adjacent to the tube for controlling the temperature of the reaction solution. The at least one light source provides a light beam passing through an incident portion of the tube to excite the reaction solution emitting a fluorescent light. The incident portion is located at a height greater than ½ of a liquid level. The sensor is adjacent to the tube for detecting the excited fluorescence. The light beam has an incident direction forming a non-straight angle with a long axis of the tube.
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