-
公开(公告)号：US20240218310A1
公开(公告)日：2024-07-04
申请号：US18089570
申请日：2022-12-28
Applicant: Industrial Technology Research Institute
Inventor： Li-An Wu , Ting-Hsuan Chen , Chih-Hung Lee , Nien-Jen Chou , Kuo-Hsing Wen , Wen-Ting Chiang
Abstract: A cell culture device configured for activating, transducing, isolating and/or expanding cells. The cell culture device includes a mixing tank and a rotary control platform. The mixing tank includes a first support, a hollow tank and a cover. The hollow tank is disposed on the first support and has a first opening, a second opening and an accommodating space. The cover covers the second opening and has a first hole, an inlet end and an outlet end. The rotary control platform includes a base, a second support, a rotating gear, an inclination control member and a micro injector. The second support is disposed on the base. The rotating gear is fixed on the first support. The inclination control member has a first part, a second part and a third part. The first part is connected to the rotating gear, and the second part is connected to the first part and the third part. The micro injector extends to the accommodating space through the first hole of the cover. The micro injector has a top end and a bottom end, the top end is fixed on the third part, and the bottom end is disposed to a bottom of the accommodating space. The micro injector is inclined towards the bottom of the accommodating space.
-
公开(公告)号：US20220169985A1
公开(公告)日：2022-06-02
申请号：US17535694
申请日：2021-11-26
Applicant: Industrial Technology Research Institute
Inventor： Ting-Hsuan Chen , Kuo-Hsing Wen , Ya-Hui Chiu , Nien-Tzu Chou , Ching-Fang Lu , Cheng-Tai Chen , Ting-Shuo Chen , Pei-Shin Jiang
IPC: C12N5/0783 , C12M1/00 , C12M1/42 , C12M1/06
Abstract: A cell activation reactor and a cell activation method are provided. The cell activation reactor includes a body, a rotating part, an upper cover, a microporous film, and multiple baffles. The body has an accommodating space, which is suitable for accommodating multiple cells and multiple magnetic beads. The rotating part is disposed in the accommodating space and includes multiple impellers. The microporous film is disposed in the accommodating space and covers multiple holes of the accommodating space. The baffles are disposed in the body. When the rotating part is driven to rotate, the interaction between the baffles and the impellers separates the cells and the magnetic beads.
-
公开(公告)号：US10183295B2
公开(公告)日：2019-01-22
申请号：US15588043
申请日：2017-05-05
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Tseng-Huang Liu , Kuo-Hsing Wen , Pei-Shin Jiang , Jie-Len Huang , Ting-Hsuan Chen
Abstract: A convective polymerase chain reaction apparatus includes a tube, a temperature control unit, at least one light source and a sensor. The tube includes a cavity used to contain a reaction solution. The reaction solution has a liquid level measured from a bottom of the cavity to a top surface of the reaction solution. The temperature control unit is disposed adjacent to the tube for controlling the temperature of the reaction solution. The at least one light source provides a light beam passing through an incident portion of the tube to excite the reaction solution emitting a fluorescent light. The incident portion is located at a height greater than ½ of a liquid level. The sensor is adjacent to the tube for detecting the excited fluorescence. The light beam has an incident direction forming a non-straight angle with a long axis of the tube.
-
Patent Agency Ranking
公开(公告)号：US11884912B2
公开(公告)日：2024-01-30
申请号：US16727057
申请日：2019-12-26
Applicant: Industrial Technology Research Institute
Inventor： Kuo-Hsing Wen , Ting-Hsuan Chen , Cheng-Tai Chen , Chien-An Chen , Su-Fung Chiu , Yung-Chi Chang , Nien-Jen Chou , Ping-Jung Wu , Shaw-Hwa Parng , Pei-Shin Jiang
Abstract: A cell culture device includes a culture unit, a gas supply unit, a first pressure unit, at least one inspecting unit and a control unit. The culture unit contains a cell culture liquid. The gas supply unit, connected with the culture unit, is used for transmitting a culture gas into the culture unit. The first pressure unit, connected with the culture unit, is used for applying a pressure to the cell culture liquid in the culture unit. The at least one inspecting unit, connected with the culture unit, is used for receiving the cell culture liquid for inspection. The control unit, electrically coupled with the culture unit, the first pressure unit, the gas supply unit and the at least one inspecting unit, is used for monitoring corresponding condition parameters to determine respective operations. In addition, a cell culture method for the cell culture device is also provided.
-
公开(公告)号：US20180104696A1
公开(公告)日：2018-04-19
申请号：US15588043
申请日：2017-05-05
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Tseng-Huang Liu , Kuo-Hsing Wen , Pei-Shin Jiang , Jie-Len Huang , Ting-Hsuan CHEN
CPC classification number: B01L7/52 , B01L7/525 , B01L2300/0654 , B01L2300/0681 , B01L2300/0832 , B01L2300/18 , B01L2400/0445 , C12Q1/686 , G01N21/00
Abstract: A convective polymerase chain reaction apparatus includes a tube, a temperature control unit, at least one light source and a sensor. The tube includes a cavity used to contain a reaction solution. The reaction solution has a liquid level measured from a bottom of the cavity to a top surface of the reaction solution. The temperature control unit is disposed adjacent to the tube for controlling the temperature of the reaction solution. The at least one light source provides a light beam passing through an incident portion of the tube to excite the reaction solution emitting a fluorescent light. The incident portion is located at a height greater than ½ of a liquid level. The sensor is adjacent to the tube for detecting the excited fluorescence. The light beam has an incident direction forming a non-straight angle with a long axis of the tube.
-
公开(公告)号：US11959101B2
公开(公告)日：2024-04-16
申请号：US17535694
申请日：2021-11-26
Applicant: Industrial Technology Research Institute
Inventor： Ting-Hsuan Chen , Kuo-Hsing Wen , Ya-Hui Chiu , Nien-Tzu Chou , Ching-Fang Lu , Cheng-Tai Chen , Ting-Shuo Chen , Pei-Shin Jiang
Abstract: A cell activation reactor and a cell activation method are provided. The cell activation reactor includes a body, a rotating part, an upper cover, a microporous film, and multiple baffles. The body has an accommodating space, which is suitable for accommodating multiple cells and multiple magnetic beads. The rotating part is disposed in the accommodating space and includes multiple impellers. The microporous film is disposed in the accommodating space and covers multiple holes of the accommodating space. The baffles are disposed in the body. When the rotating part is driven to rotate, the interaction between the baffles and the impellers separates the cells and the magnetic beads.
-
公开(公告)号：US20230201840A1
公开(公告)日：2023-06-29
申请号：US17564243
申请日：2021-12-29
Applicant: Industrial Technology Research Institute
Inventor： Chun-Chuan Lin , Hsiao-Yue Tsao , Shih-Bin Luo , Kuo-Hsing Wen , Chien-Chih Kuo , Ping-Jung Wu , Ruey-Shyan Hong , Ting-Hsuan Chen
CPC classification number: B01L7/52 , G01N21/6486 , B01L9/527 , G01N2021/6419 , G01N2021/6421 , C12Q1/686
Abstract: A convective polymerase chain reaction apparatus and an optical detecting method thereof are provided. The optical detecting method includes the following steps. A substance in a tube to be tested is heated. At least two monochromatic lights are provided and are combined using a light combining element to irradiate the tube to be tested. At least two excited lights generated by exciting the substance in the tube to be tested by the at least two monochromatic lights are sensed.
-
公开(公告)号：US09505003B2
公开(公告)日：2016-11-29
申请号：US14582697
申请日：2014-12-24
Applicant: Industrial Technology Research Institute
Inventor： Chih-Hsiang Sung , Tseng-Huang Liu , Ruey-Shyan Hong , Ting-Hsuan Chen , Ping-Jung Wu , Kuo-Hsing Wen , Wan-Chi Chang
CPC classification number: B01L7/52 , B01L9/06 , B01L2200/18 , B01L2300/046 , B01L2300/0663 , B01L2300/1805 , B01L2300/1844
Abstract: A portable real-time heating and detection device includes a body, a cover and a detection unit. The body has an opening, and a base. The cover has a control unit and a fix unit. The detection unit is disposed on the base of the body and has a thermostat, an optical excitation, an optical detection, and a circuit board. The thermostat is disposed close to the opening and has at least one thermostat zone. The optical exciter is disposed between the thermostat and the base. The optical detector is disposed between the thermostat and the opening. The circuit board is electrical coupled to the control unit, the thermostat, the optical excitation, and the optical detector, respectively.
Abstract translation: 便携式实时加热和检测装置包括主体，盖和检测单元。 身体有一个开口和一个基地。 盖具有控制单元和固定单元。 检测单元设置在主体的基座上并具有恒温器，光学激励，光学检测和电路板。 恒温器靠近开口设置，并具有至少一个恒温区。 光激发器设置在恒温器和基座之间。 光学检测器设置在恒温器和开口之间。 电路板分别电耦合到控制单元，恒温器，光学激励和光学检测器。
-
-
-
-
-
-
-
Search Results
8
records
(took 0.014 seconds)
