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145 条记录 (耗时 0.032 秒)

    Stent With Improved Mechanical Properties
    2.
    发明申请
    Stent With Improved Mechanical Properties 审中-公开
    具有改善机械性能的支架

    公开(公告)号：US20080319534A1

    公开(公告)日：2008-12-25

    申请号：US11767308

    申请日：2007-06-22

    申请人： Matthew J. Birdsall ,  Gianfranco Pellegrini ,  Justin Goshgarian ,  Jeffrey Allen

    发明人： Matthew J. Birdsall ,  Gianfranco Pellegrini ,  Justin Goshgarian ,  Jeffrey Allen

    IPC分类号： A61F2/06

    CPC分类号： A61F2/88 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91558 ,  A61F2220/0058 ,  A61F2250/0036

    摘要： A stent includes a central portion having a first waveform. The first waveform is wrapped around a longitudinal axis of the stent at a pitch to define a plurality of helical turns. The stent also includes an end segment connected to one end of the central portion. The end segment has a second waveform that includes a plurality of struts and a plurality of crowns. Each of the plurality of struts has a different length so that peaks of the crowns that define an end of the stent lie within a plane that is substantially perpendicular to the longitudinal axis. Cross-sectional areas of the struts having different lengths vary so that the struts move substantially uniformly during radial contraction and/or radial expansion of the stent.

    摘要翻译： 支架包括具有第一波形的中心部分。 第一波形以间距缠绕在支架的纵向轴线上以限定多个螺旋形匝。 支架还包括连接到中心部分的一端的端部段。 端部段具有包括多个支柱和多个冠部的第二波形。 多个支柱中的每一个具有不同的长度，使得限定支架的端部的冠部的顶点位于基本上垂直于纵向轴线的平面内。 具有不同长度的支柱的横截面积变化，使得支柱在支架的径向收缩和/或径向膨胀期间基本均匀地移动。

    Bioabsorbable Stent Having a Radiopaque Marker
    3.
    发明申请
    Bioabsorbable Stent Having a Radiopaque Marker 审中-公开
    具有不透射线标记的生物可吸收支架

    公开(公告)号：US20090204203A1

    公开(公告)日：2009-08-13

    申请号：US12027715

    申请日：2008-02-07

    申请人： Jeffrey Allen ,  Matthew J. Birdsall

    发明人： Jeffrey Allen ,  Matthew J. Birdsall

    IPC分类号： A61F2/82

    CPC分类号： A61F2/915 ,  A61F2210/0004 ,  A61F2230/0013 ,  A61F2250/003 ,  A61F2250/0036 ,  A61F2250/0098

    摘要： A bioabsorbable stent includes one or more radiopaque markers. The stent body may include a generally cylindrical body portion and a marker support for receiving the one or more marker(s). The marker support may be connected to an end of the body portion, or may be an integral portion of the body portion. By selectively controlling dissolution of the biodegradable material of the marker support, the marker support will remain intact for a sufficient time to allow for the marker to endothelialize and therefore prevent the marker from dislodging and embolizing. The controlled dissolution may be accomplished via one or more of the following mechanisms, including increasing the cross-sectional thickness of the marker support, passivating or oxidizing the marker support, utilizing a different, slower absorbing material for the marker support, utilizing a bioabsorbable polymeric coating on the marker support, or protecting the marker support with a sacrificial anode.

    摘要翻译： 生物可吸收支架包括一个或多个不透射线的标记。 支架主体可以包括大致圆柱形主体部分和用于接收一个或多个标记的标记支撑件。 标记支撑件可以连接到主体部分的端部，或者可以是主体部分的整体部分。 通过选择性地控制标记载体的可生物降解材料的溶解，标记物载体将保持完整的足够的时间以允许标记物内皮化并因此防止标记物移出和栓塞。 受控的溶解可以通过一种或多种以下机制来实现，包括使用生物可吸收聚合物的标记载体的不同的较慢的吸收材料来增加标记物载体的横截面厚度，钝化或氧化标记物载体 涂覆在标记支撑件上，或用牺牲阳极保护标记支撑件。

    Stent With Therapeutic Agent Delivery Structures in Low Strain Regions
    4.
    发明申请
    Stent With Therapeutic Agent Delivery Structures in Low Strain Regions 审中-公开
    在低应变区域中具有治疗剂递送结构的支架

    公开(公告)号：US20080249599A1

    公开(公告)日：2008-10-09

    申请号：US11696816

    申请日：2007-04-05

    申请人： Jeffrey Allen ,  Scott Doig ,  Matthew J. Birdsall ,  Darrel Untereker

    发明人： Jeffrey Allen ,  Scott Doig ,  Matthew J. Birdsall ,  Darrel Untereker

    IPC分类号： A61F2/82

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91558 ,  A61F2250/0023 ,  A61F2250/0067

    摘要： A system for treating abnormalities of the cardiovascular system includes a stent having a plurality of therapeutic agent-carrying regions and non therapeutic agent-carrying regions. The therapeutic agent-carrying regions are located within low strain regions of the stent and the non therapeutic agent-carrying regions are located within high strain regions of the stent. Another embodiment of the invention includes a method of manufacturing a therapeutic agent-carrying stent comprising forming a stent framework and applying a formulation containing one or more therapeutic agents to the stent framework while preventing the therapeutic agents from contacting the high strain regions of the stent framework.

    摘要翻译： 用于治疗心血管系统异常的系统包括具有多个治疗剂携带区域和非治疗剂携带区域的支架。 治疗剂携带区域位于支架的低应变区域内，并且非治疗剂携带区域位于支架的高应变区域内。 本发明的另一个实施方案包括制备治疗剂携带支架的方法，包括形成支架框架并将含有一种或多种治疗剂的制剂施用于支架框架，同时防止治疗剂接触支架框架的高应变区域 。

    Stent Having Controlled Porosity for Improved Ductility
    5.
    发明申请
    Stent Having Controlled Porosity for Improved Ductility 审中-公开
    具有控制孔隙度的支架以改善延展性

    公开(公告)号：US20080208352A1

    公开(公告)日：2008-08-28

    申请号：US11679426

    申请日：2007-02-27

    申请人： Michael Krivoruchko ,  Jeffrey Allen ,  Matthew J. Birdsall

    发明人： Michael Krivoruchko ,  Jeffrey Allen ,  Matthew J. Birdsall

    IPC分类号： A61F2/86

    CPC分类号： A61L31/022 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2230/0013 ,  A61F2250/0023 ,  A61L31/146

    摘要： An endoluminal prosthesis for placement in a body lumen of a metallic material having controlled porosity for improved ductility. The metallic material may be formed into a stent structure or a wire or sheet, which may then be formed into the stent structure. The porous network of the stent includes pores that range from nanometer scale to micron scale. The controlled porosity accommodates volume changes as well as provides a barrier to crack propagation to allow alloy steels and amorphous metal materials, which would otherwise be considered too brittle for the demands of intraventional use, to be utilized in a stent.

    摘要翻译： 用于放置在具有受控孔隙度的金属材料的体腔中用于改善延展性的腔内假体。 金属材料可以形成为可以形成支架结构的支架结构或线或片。 支架的多孔网络包括范围从纳米级到微米级的孔。 受控的孔隙率适应体积变化，并且提供裂纹扩展的障碍，以允许在支架中使用合金钢和非晶态金属材料，否则其将被认为对于常规使用的要求太脆。