摘要:
Provided are highly conserved antigens and epitopes of SARS-CoV-2 that can be used in vaccines and to produce bindings proteins (e.g., antibodies) for treating, preventing, or reducing the risks of infections caused by β-coronaviruses such as SARS-CoV-2, and as targets for detecting SARS-CoV-2 infection
摘要:
A trans-impedance filter circuit provided according to an aspect of the present invention contains an operational amplifier, a first resistor, a first capacitor, a second resistor, and a second capacitor. The second capacitor is connected in parallel between the inverting input terminal and an output path of the operational amplifier. The second resistor is connected between the output terminal of the operational amplifier and a second node on a path connecting the input signal to the inverting input terminal. The first resistor is coupled between the first node and inverting input terminal of the operational amplifier. The first capacitor is coupled between the first node and Vss. Due to such connections, the filter circuit operates as a second order filter circuit, thereby providing a desired high level of filtering. Also, as the filter circuit is implemented with a single operational amplifier, the power and area requirements are reduced.
摘要:
Methods and apparatus for error cancelation in calibrated current sources are disclosed. In an example, a digital to analog converter to convert digital bits into an analog output signal is described, including a plurality of current sources, a calibrator, and a current source selector. The example current sources output substantially identical currents, and the calibrator is selectively coupled to sequentially calibrate the current sources to a reference current. The example current source selector assigns respective ones of the plurality of current sources to the digital bits in accordance with a bit-to-current source sequence selected to reduce current error in the analog output and changes the assignments based on the current source coupled to the calibrator.
摘要:
Methods and apparatus for error cancelation in calibrated current sources are disclosed. In an example, a digital to analog converter to convert digital bits into an analog output signal is described, including a plurality of current sources, a calibrator, and a current source selector. The example current sources output substantially identical currents, and the calibrator is selectively coupled to sequentially calibrate the current sources to a reference current. The example current source selector assigns respective ones of the plurality of current sources to the digital bits in accordance with a bit-to-current source sequence selected to reduce current error in the analog output and changes the assignments based on the current source coupled to the calibrator.
摘要:
In an apparatus and method for monitoring defects in wafers, a monitoring circuit is fabricated on an area of each one of the wafers. The monitoring circuit includes representative devices that replicate similar devices located in a die area of the wafers. Defects if present in the representative devices contribute to a generation of a noise, thereby causing an imbalance in a differential signal measurable across selected ones of the representative devices. A digitizing circuit that uses a common mode voltage as a reference to measure the imbalance digitizes the differential signal to a digital signal, the digital signal being indicative of the noise generated by the defects. The digital signal is stored over a configurable time interval to form a digital bit stream. The digital bit stream is compared to a reference to determine whether the defeats are within an allowable range.
摘要:
In a method and apparatus for trimming values of load resistors to reduce variations there between, a common mode feedback loop (CMFBL) included in a differential amplifier is switched from operating in a closed loop mode to operate in an open loop mode. The CMFBL includes an operational amplifier (OA) generating an output signal. A selector switch, coupled to receive the output signal, is operable to switch a path of the output signal in response to a CAL signal. In the closed loop mode, the selector switch routes the output signal to a feedback loop to provide a regulated current to the load resistors. In the open loop mode, the OA operates as a comparator and the output signal is provided as a digital signal. The selector switch provides the digital signal to a controller to digitally trim the values of the load resistors.
摘要:
In an apparatus and method for monitoring defects in wafers, a monitoring circuit is fabricated on an area of each one of the wafers. The monitoring circuit includes representative devices that replicate similar devices located in a die area of the wafers. Defects if present in the representative devices contribute to a generation of a noise, thereby causing an imbalance in a differential signal measurable across selected ones of the representative devices. A digitizing circuit that uses a common mode voltage as a reference to measure the imbalance digitizes the differential signal to a digital signal, the digital signal being indicative of the noise generated by the defects. The digital signal is stored over a configurable time interval to form a digital bit stream. The digital bit stream is compared to a reference to determine whether the defects are within an allowable range.
摘要:
In an apparatus and method for improving performance of a third order, double-sampled, sigma-delta modulator (SDM), a first one of three feedback elements included in a feedback loop of the SDM is selected to complete the feedback loop during a first half-cycle of the clock used for the double-sampling. The first one is restricted from being reselected during a subsequent half-cycle of the clock until the first one is reset. A second one of the three feedback elements is selected during a second half-cycle of the clock that is consecutive to the first half-cycle, the second one being different than the first one. A third one of the three feedback elements is selected during a third half-cycle of the clock that is consecutive to the second half-cycle, the third one being different than the second one.
摘要:
In an apparatus and method for improving performance of a third order, double-sampled, sigma-delta modulator (SDM), a first one of three feedback elements included in a feedback loop of the SDM is selected to complete the feedback loop during a first half-cycle of the clock used for the double-sampling. The first one is restricted from being reselected during a subsequent half-cycle of the clock until the first one is reset. A second one of the three feedback elements is selected during a second half-cycle of the clock that is consecutive to the first half-cycle, the second one being different than the first one. A third one of the three feedback elements is selected during a third half-cycle of the clock that is consecutive to the second half-cycle, the third one being different than the second one.
摘要:
A pipeline ADC implemented with both general charge redistribution stages and flip-around charge redistribution stages. Using the flip-around charge redistribution stages leads to reduced power/area consumption, but could lead to accumulation and propagation of errors. general charge redistribution stages are used to control/contain the errors. As a result, the ADC is implemented to achieve an acceptable bit error and power efficiency combination. According to another aspect of the present invention, the first stage is implemented as a flip-around charge redistribution stage (in combination with general charge redistribution stages in subsequent stages) since there is no accumulation of error from prior stages, and implementing the first stage as a flip-around charge redistribution stage gives maximum advantages in power efficiency.