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公开(公告)号：US20160079060A1
公开(公告)日：2016-03-17
申请号：US14788723
申请日：2015-06-30
申请人： Joseph M. Jacobson , David Kong , Vikas Anant , Ashley Salomon , Saul Griffith , Will DelHagen , Vikrant Agnihotri
发明人： Joseph M. Jacobson , David Kong , Vikas Anant , Ashley Salomon , Saul Griffith , Will DelHagen , Vikrant Agnihotri
IPC分类号： H01L21/02 , H01L21/285 , H01L21/263
CPC分类号： H01L21/02631 , B82Y10/00 , B82Y40/00 , C23C14/024 , C23C14/048 , C23C14/228 , C23C16/047 , C23C16/45525 , C23C16/45555 , H01L21/02225 , H01L21/02266 , H01L21/0228 , H01L21/02351 , H01L21/0262 , H01L21/02664 , H01L21/2633 , H01L21/2855 , H01L21/28556 , H01L27/30 , H01L51/0002 , Y10S977/888 , Y10S977/891
摘要： A technique for forming nanostructures including introducing a plurality of molecular-size scale and/or nanoscale building blocks to a region near a substrate and simultaneously scanning a pattern on the substrate with an energy beam, wherein the energy beam causes a change in at least one physical property of at least a portion of the building blocks, such that a probability of the portion of the building blocks adhering to the pattern scanned by the energy beam is increased, and wherein the building blocks adhere to the pattern to form the structure. The energy beam and at least a portion of the building blocks may interact by electrostatic interaction to form the structure.
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公开(公告)号：US20160006813A1
公开(公告)日：2016-01-07
申请号：US14698840
申请日：2015-04-28
IPC分类号： H04L29/08 , H04B1/3827 , H04B17/318
CPC分类号： H04B1/3827 , H04B1/3888 , H04B5/0037 , H04B5/0075 , H04B2001/3894 , H04W84/18
摘要： A platform for context-aware experimentation includes a housing for one or more sensors for obtaining data pertaining to an on-going experiment, a communications subsystem for transmitting data obtained by the sensors, and a microcontroller for receiving data from the sensors, providing it to the communications subsystem, and possibly controlling the sensors. The housing may be a tube, which may be configured to hold a sample and may have a cap, or a waterproof package, which may have an opening to admit at least part of a sample. The platform may include a power source. The platform may include a computer processor, located outside the housing, for analyzing the data obtained by the sensors, determining the experimental context in which the sensors are operating and/or which experimental step in a protocol is being performed, and/or reminding users of required parameters for the steps in the protocol.
摘要翻译： 用于上下文感知实验的平台包括用于获得与正在进行的实验有关的数据的一个或多个传感器的壳体，用于传送由传感器获得的数据的通信子系统，以及用于从传感器接收数据的微控制器， 通信子系统，并且可能控制传感器。 壳体可以是管，其可以被配置成保持样品并且可以具有帽或防水包，其可以具有允许至少部分样品的开口。 平台可以包括电源。 平台可以包括位于壳体外部的计算机处理器，用于分析由传感器获得的数据，确定传感器正在操作的实验上下文和/或正在执行协议中的哪个实验步骤和/或提醒用户 需要参数的协议中的步骤。
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公开(公告)号：US09070556B2
公开(公告)日：2015-06-30
申请号：US14600676
申请日：2015-01-20
申请人： Joseph M. Jacobson , David Kong , Vikas Anant , Ashley Salomon , Saul Griffith , Will DelHagen , Vikrant Agnihotri
发明人： Joseph M. Jacobson , David Kong , Vikas Anant , Ashley Salomon , Saul Griffith , Will DelHagen , Vikrant Agnihotri
IPC分类号： H01L51/00 , H01L21/02 , H01L21/285 , H01L27/30
CPC分类号： H01L21/02631 , B82Y10/00 , B82Y40/00 , C23C14/024 , C23C14/048 , C23C14/228 , C23C16/047 , C23C16/45525 , C23C16/45555 , H01L21/02225 , H01L21/02266 , H01L21/0228 , H01L21/02351 , H01L21/0262 , H01L21/02664 , H01L21/2633 , H01L21/2855 , H01L21/28556 , H01L27/30 , H01L51/0002 , Y10S977/888 , Y10S977/891
摘要： A technique for forming nanostructures including introducing a plurality of molecular-size scale and/or nanoscale building blocks to a region near a substrate and simultaneously scanning a pattern on the substrate with an energy beam, wherein the energy beam causes a change in at least one physical property of at least a portion of the building blocks, such that a probability of the portion of the building blocks adhering to the pattern scanned by the energy beam is increased, and wherein the building blocks adhere to the pattern to form the structure. The energy beam and at least a portion of the building blocks may interact by electrostatic interaction to form the structure.
摘要翻译： 一种用于形成纳米结构的技术，包括将多个分子尺度尺度和/或纳米尺度结构单元引入到衬底附近的区域，同时用能量束扫描衬底上的图案，其中能量束引起至少一个 构造块的至少一部分的物理性质，使得构成块的部分附着到由能量束扫描的图案的概率增加，并且其中构建块粘附到图案以形成结构。 能量束和至少一部分构建块可通过静电相互作用而形成结构。
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公开(公告)号：US20130197214A1
公开(公告)日：2013-08-01
申请号：US13747373
申请日：2013-01-22
IPC分类号： C08B37/16
CPC分类号： C08B37/0012 , B05D1/00 , C01B13/00 , C08B37/0015 , Y10S977/778 , Y10S977/882 , Y10T428/25 , Y10T428/2991
摘要： Fabrication and arrangement of nanoparticles into one-dimensional linear chains is achieved by successive chemical reactions, each reaction adding one or more nanoparticles by building onto exposed, unprotected linker functionalities. Optionally, protecting groups may be used to control and organize growth. Nanoparticle spheres are functionalized in a controlled manner in order to enable covalent linkages. Functionalization of nanoparticles is accomplished by either ligand exchange or chemical modification of the terminal functional groups of the capping ligand. Nanoparticle chains are obtained by a variety of connectivity modes such as direct coupling, use of linker molecules, and use of linear polymeric templates. In particular, a versatile building block system is obtained through controlled monofunctionalization of nanoparticles.
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5.发明授权Methods for high fidelity production of long nucleic acid molecules with error control 有权用于具有错误控制的长核酸分子的高保真度生产方法公开(公告)号：US08263335B2
公开(公告)日：2012-09-11
申请号：US13093807
申请日：2011-04-25
CPC分类号： B01J19/0046 , B01J2219/00608 , B01J2219/00659 , B01J2219/00722 , C12Q1/6827 , C12Q1/6837 , C12Q1/6846 , C12Q1/6848 , C12Q2565/518 , C12Q2537/149 , C12Q2521/514 , C12Q2537/113 , C12Q2565/537 , C12Q2565/513
摘要： A method for synthesizing a nucleic acid having a desired sequence and length comprises providing a solid support having an immobilized nucleic acid, performing a nucleic acid addition reaction to elongate the immobilized nucleic acid by adding a nucleotide or an oligonucleotide to the nucleic acid, determining whether the nucleotide or the oligonucleotide is added to the nucleic acid by detecting whether there is an increase in electrophoretic force applied to the solid support when an electric field and a magnetic field gradient are applied to the support, wherein the increase in electrophoretic force applied to the support is caused by adding the nucleotide or the oligonucleotide to the nucleic acid, repeating the addition reaction and determination steps if the nucleotide or the oligonucleotide is not added to the nucleic acid, and continuing until the immobilized nucleic acid has a desired sequence and length.
摘要翻译： 合成具有所需序列和长度的核酸的方法包括提供具有固定化核酸的固体支持物，通过向核酸中加入核苷酸或寡核苷酸进行核酸加成反应以延长固定化的核酸，确定是否 通过检测当对载体施加电场和磁场梯度时施加到固体支持物上的电泳力是否增加，将核苷酸或寡核苷酸加入到核酸中，其中施加到载体上的电泳力的增加 通过向核酸添加核苷酸或寡核苷酸引起支持，如果核苷酸或寡核苷酸未加入到核酸中，则重复加成反应和测定步骤，并持续直到固定的核酸具有所需的序列和长度。
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公开(公告)号：US08213076B2
公开(公告)日：2012-07-03
申请号：US12840697
申请日：2010-07-21
申请人： Jonathan D. Albert , Barrett Comiskey , Joseph M. Jacobson , Libing Zhang , Andrew Loxley , Robert D. Feeney , Paul S. Drzaic , Ian D. Morrison
发明人： Jonathan D. Albert , Barrett Comiskey , Joseph M. Jacobson , Libing Zhang , Andrew Loxley , Robert D. Feeney , Paul S. Drzaic , Ian D. Morrison
CPC分类号： G02F1/167 , G02F2001/1676 , G09G3/344 , G09G2300/0434
摘要： Novel addressing schemes for controlling electronically addressable displays include a scheme for rear-addressing displays, which allows for in-plane switching of the display material. Other schemes include a rear-addressing scheme which uses a retroreflecting surface to enable greater viewing angle and contrast. Another scheme includes an electrode structure that facilitates manufacture and control of a color display. Another electrode structure facilitates addressing a display using an electrostatic stylus. Methods of using the disclosed electrode structures are also disclosed. Another scheme includes devices combining display materials with silicon transistor addressing structures.
摘要翻译： 用于控制电子可寻址显示器的新型寻址方案包括用于后寻址显示器的方案，其允许显示材料的平面内切换。 其他方案包括使用回射表面以实现更大视角和对比度的后方寻址方案。 另一方案包括有利于彩色显示器的制造和控制的电极结构。 另一种电极结构有助于使用静电触针来寻址显示器。 还公开了使用所公开的电极结构的方法。 另一种方案包括将显示材料与硅晶体管寻址结构组合在一起的装置。
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公开(公告)号：US08206952B2
公开(公告)日：2012-06-26
申请号：US13019092
申请日：2011-02-01
CPC分类号： C12P19/34 , C12Q1/6825 , C12Q1/6834 , C12Q1/6848 , C12Q2565/518 , C12Q2565/513 , C12Q2521/514
摘要： In a method for synthesizing a long nucleic acid molecule, a first immobilized nucleic acid has a first 5′ region and a first 3′ region and a second immobilized nucleic acid has a second 5′ region and a second 3′ region. The second 3′ region and the first 5′ region have identical nucleic acid sequences. An oligonucleotide is hybridized to the first 3′ region, extending the hybridized oligonucleotide and producing a first extension product having a 3′ region that is complementary to the first 5′ region. The 3′ region of the first extension product is hybridized to the second 3′ region, extending the 3′ region of the first extension product and producing a synthesized nucleic acid molecule having a 3′ region that is complementary to the second 5′ region, wherein the synthesized nucleic acid molecule has a sequence complementary to the first and second 3′ and 5′ regions.
摘要翻译： 在合成长核酸分子的方法中，第一固定化核酸具有第一5'区和第3'区，第二固定化核具有第二5'区和第二3'区。 第二个3'区和第5个'区具有相同的核酸序列。 将寡核苷酸与前3'区域杂交，延伸杂交的寡核苷酸并产生具有与前5'区互补的3'区的第一延伸产物。 第一延伸产物的3'区域与第二3'区域杂交，延伸第一延伸产物的3'区域并产生具有与第二5'区域互补的3'区域的合成核酸分子， 其中所述合成的核酸分子具有与所述第一和第二3'和5'区互补的序列。
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8.发明授权公开(公告)号：US07999787B2
公开(公告)日：2011-08-16
申请号：US11162188
申请日：2005-08-31
申请人： Karl R. Amundson , Alexi C. Arango , Joseph M. Jacobson , Thomas H. Whitesides , Michael D. McCreary , Richard J. Paolini, Jr.
发明人： Karl R. Amundson , Alexi C. Arango , Joseph M. Jacobson , Thomas H. Whitesides , Michael D. McCreary , Richard J. Paolini, Jr.
IPC分类号： G09G3/34
CPC分类号： G02F1/167 , E06B9/24 , E06B2009/2464 , G02F2001/1672 , G02F2001/1676 , G02F2001/1678 , G02F2201/12 , G09G3/34
摘要： A dielectrophoretic display has a substrate having walls defining a cavity, the cavity having a viewing surface and a side wall inclined to the viewing surface. A fluid is contained within the cavity; and a plurality of particles are present in the fluid. There is applied to the substrate an electric field effective to cause dielectrophoretic movement of the particles so that the particles occupy only a minor proportion of the viewing surface.
摘要翻译： 介电泳显示器具有具有限定空腔的壁的基板，空腔具有观察表面和与观察表面倾斜的侧壁。 流体包含在腔内; 并且流体中存在多个颗粒。 向基板施加有效地引起颗粒的介电泳移动的电场，使得颗粒仅占观察表面的较小比例。
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9.发明申请公开(公告)号：US20110193841A1
公开(公告)日：2011-08-11
申请号：US13094184
申请日：2011-04-26
申请人： Karl R. Amundson , Alexi C. Arango , Joseph M. Jacobson , Thomas H. Whitesides , Michael D. McCreary , Richard J. Paolini, JR.
发明人： Karl R. Amundson , Alexi C. Arango , Joseph M. Jacobson , Thomas H. Whitesides , Michael D. McCreary , Richard J. Paolini, JR.
CPC分类号： G02F1/167 , G02F1/13306 , G02F1/1681 , G02F2001/1678 , G09G3/344 , G09G2310/068
摘要： A dielectrophoretic display has a substrate having walls defining a cavity, the cavity having a viewing surface and a side wall inclined to the viewing surface. A fluid is contained within the cavity; and a plurality of particles are present in the fluid. There is applied to the substrate an electric field effective to cause dielectrophoretic movement of the particles so that the particles occupy only a minor proportion of the viewing surface.
摘要翻译： 介电泳显示器具有具有限定空腔的壁的基板，空腔具有观察表面和与观察表面倾斜的侧壁。 流体包含在腔内; 并且流体中存在多个颗粒。 向基板施加有效地引起颗粒的介电泳移动的电场，使得颗粒仅占观察表面的较小比例。
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公开(公告)号：US07583251B2
公开(公告)日：2009-09-01
申请号：US11799377
申请日：2007-05-01
IPC分类号： G09G3/34
CPC分类号： B41J2/01 , B41J2/02 , B41J3/4076 , B82Y10/00 , B82Y20/00 , C09D11/30 , C09D11/50 , G02B26/026 , G02F1/133305 , G02F1/133348 , G02F1/13336 , G02F1/1334 , G02F1/1343 , G02F1/134309 , G02F1/13439 , G02F1/1345 , G02F1/135 , G02F1/1365 , G02F1/167 , G02F1/172 , G02F1/19 , G02F2001/1676 , G02F2202/12 , G02F2202/28 , G04B47/00 , G06F15/0283 , G06K19/07703 , G09F9/302 , G09F9/372 , G09G3/344 , G09G3/38 , G09G2310/0267 , G09G2310/0275 , G09G2380/02 , H01L27/12 , H01L27/28 , H01L51/0036 , H01L51/0038 , H01L51/0045 , H01L51/005 , H01L51/0051 , H01L51/0052 , H01L51/0077 , H01L51/0078 , H01L51/0508 , H01L51/0512 , H05K1/097 , H05K3/105 , H05K3/1241
摘要： A dielectrophoretic display comprises a substrate having walls defining at least one cavity, the cavity having a viewing surface and a side wall inclined to the viewing surface; a suspending fluid contained within the cavity; a plurality of at least one type of particle suspended within the suspending fluid; and means for applying to the fluid an electric field effect effective to cause dielectrophoretic movement of the particles to the side wall of the cavity.
摘要翻译： 介电电泳显示器包括具有限定至少一个空腔的壁的基板，空腔具有观察表面和与观察表面倾斜的侧壁; 包含在腔内的悬浮液; 悬浮在悬浮液中的多个至少一种类型的颗粒; 以及用于向流体施加有效地引起颗粒到空腔侧壁的介电泳移动的电场效应的装置。
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