公开(公告)号：US20100158890A1

公开(公告)日：2010-06-24

申请号：US12282695

申请日：2007-03-15

申请人： Kenichi Tanaka ,  Enrico Di Cera ,  Andras Gruber ,  Stephen Raymond Hanson

发明人： Kenichi Tanaka ,  Enrico Di Cera ,  Andras Gruber ,  Stephen Raymond Hanson

IPC分类号： A61K38/48 ,  G01N33/53 ,  A61P7/04

CPC分类号： A61K38/4833 ,  G01N33/86 ,  G01N2333/7452

摘要： The present invention provides methods for inhibiting the anticoagulation effect of a thrombin inhibitor in a patient in need thereof comprising administration of a therapeutically effective amount of a variant prothrombin or thrombin that is capable of binding the thrombin inhibitor and that has reduced procoagulant activity. Variant prothrombins or thrombins of use in the methods of the present invention include thrombin mutants W215A, W215A/E217A, or variants thereof in which the amino acids at positions 215 and/or 217 are alanine. Methods are also provided in which the thrombin mutants are administered with an additional active agent, particularly hemostatic agents such as activated factor VII or activated prothrombin complex concentrate. In one embodiment of the invention, the methods are useful in the treatment of patients in which a direct thrombin inhibitor has been administered, particularly argatroban. The present invention further provides a method for quantifying the concentration of an anticoagulant in the plasma or whole blood of a patient using a variant prothrombin or thrombin titration assay.

摘要翻译： 本发明提供了抑制凝血酶抑制剂在有需要的患者中的抗凝效果的方法，其包括施用治疗有效量的能够结合凝血酶抑制剂并降低促凝血活性的变体凝血酶原或凝血酶。 在本发明的方法中使用的变体前血栓素或血栓素包括其中215位和/或217位的氨基酸为丙氨酸的凝血酶突变体W215A，W215A / E217A或其变体。 还提供了其中凝血酶突变体与另外的活性剂，特别是止血剂如活化因子VII或活化的凝血酶原复合物浓缩物一起施用的方法。 在本发明的一个实施方案中，所述方法可用于治疗已经施用直接凝血酶抑制剂的患者，特别是阿加曲班。 本发明还提供了使用变体凝血酶原或凝血酶滴定测定来定量患者血浆或全血中抗凝血剂浓度的方法。

公开(公告)号：US09393691B2

公开(公告)日：2016-07-19

申请号：US13147415

申请日：2010-02-10

申请人： Akio Noda ,  Haruhisa Okuda ,  Kenichi Tanaka ,  Tetsuo Sawaragi ,  Hiroshi Matsuhisa ,  Yasuyoshi Yokokouji ,  Hideo Utsuno ,  Masaharu Komori ,  Hajime Mizuyama ,  Hiroaki Nakanishi ,  Yukio Horiguchi ,  Takehisa Kouda ,  Kazuhiro Izui

发明人： Akio Noda ,  Haruhisa Okuda ,  Kenichi Tanaka ,  Tetsuo Sawaragi ,  Hiroshi Matsuhisa ,  Yasuyoshi Yokokouji ,  Hideo Utsuno ,  Masaharu Komori ,  Hajime Mizuyama ,  Hiroaki Nakanishi ,  Yukio Horiguchi ,  Takehisa Kouda ,  Kazuhiro Izui

IPC分类号： B25J9/06 ,  B25J9/16 ,  G05B19/42

CPC分类号： B25J9/1661 ,  G05B19/42 ,  G05B2219/36404 ,  G05B2219/39527 ,  G05B2219/40111 ,  G05B2219/40613

摘要： An industrial robot system may enable a reduction in an installation/adjustment period, and an increase in a no-error continuous operation period. The system includes an action planning section for temporary halts, an error-inducing-task restraining section, a section for teaching task, an operation mastering section, a hand library, an optimum-task-operation generating section, a specific task library, an error-recovery-task teaching section, an error recovery library, a finger-eye-camera measurement section including an omnidirectional mirror, a three-dimensional recognition section, a controller, a manipulator, and a hand with a plurality of fingers.

摘要翻译： 工业机器人系统可以实现安装/调整周期的减少以及无错误的连续操作期间的增加。 该系统包括用于暂时停止的动作规划部，错误诱导任务抑制部，教学任务部，操作母版部，手库，最优任务动作生成部，特定任务库， 错误恢复任务教学部分，错误恢复库，包括全向镜，三维识别部分，控制器，操纵器和具有多个手指的手的手指相机测量部分。

公开(公告)号：US09199777B2

公开(公告)日：2015-12-01

申请号：US11720997

申请日：2005-12-07

申请人： Yoshinori Nanba ,  Kenichi Tanaka

发明人： Yoshinori Nanba ,  Kenichi Tanaka

IPC分类号： B65D33/16 ,  A44B1/04 ,  B65D75/66 ,  B65D33/25

摘要： A tearing guide strip 23 is integrated with a base part 21a or 21b of at least one of a male member 2a and a female member 2b constituting a zipper 2 in a peelable manner to improve the tearing unsealing ability of a zipper-equipped bag provided with an interlocking type zipper enabling resealing and unsealing after the bag is unsealed.

公开(公告)号：US09073444B2

公开(公告)日：2015-07-07

申请号：US13532957

申请日：2012-06-26

申请人： Akira Ito ,  Mitsuru Fujita ,  Shinji Katoh ,  Kenichi Tanaka ,  Yukitsugu Sakaguchi

发明人： Akira Ito ,  Mitsuru Fujita ,  Shinji Katoh ,  Kenichi Tanaka ,  Yukitsugu Sakaguchi

IPC分类号： H02J7/00 ,  B60L11/18 ,  B60L1/00

CPC分类号： B60L11/1838 ,  B60L1/00 ,  H02J7/0004 ,  H02J7/0068 ,  H02J7/007 ,  Y02T10/7005 ,  Y02T10/7072 ,  Y02T90/121 ,  Y02T90/128 ,  Y02T90/14 ,  Y02T90/163

摘要： A battery charging system for a vehicle, capable of charging a vehicle battery pack properly in a short time even during driving a vehicle-mounted electrical load. The battery charging system includes the battery pack mounted in the vehicle, the vehicle-mounted electrical load that can be driven by a current from the battery pack, and a battery charge controller that controls charging of the battery pack. When the battery pack is charged by using an external battery charger during operation of the load, the battery charge controller requires the external battery charger to supply a sum current that is a sum of a current for charging the battery pack and a current for driving the load to the vehicle.

摘要翻译： 一种用于车辆的电池充电系统，其能够即使在车载电力负载的驱动期间也能在短时间内正确地对车辆电池组充电。 电池充电系统包括安装在车辆中的电池组，可由来自电池组的电流驱动的车载电气负载，以及控制电池组充电的电池充电控制器。 当在负载运行期间使用外部电池充电器对电池组进行充电时，电池充电控制器要求外部电池充电器提供总和电流，该电流是用于对电池组充电的电流和用于驱动电池的电流之和 载入车辆。

公开(公告)号：US09011006B2

公开(公告)日：2015-04-21

申请号：US11630955

申请日：2005-06-27

申请人： Shuichi Goto ,  Kenichi Tanaka

发明人： Shuichi Goto ,  Kenichi Tanaka

IPC分类号： B65D33/00 ,  B65D65/26 ,  B65D77/32 ,  B65D33/25

CPC分类号： B65D33/2575 ,  B65D33/2508 ,  B65D33/2533 ,  B65D77/32

摘要： A bag 1 with a reclosable tape includes a reclosable tape 20 having a male fastener part 21 and a female fastener part 22 attached to one inner surface of a bag body 10, a cut tape 23 provided between mounting base parts 212 and 222 of those fastener parts, and an easily unsealable structure 50 formed on the mounting base part 212 adjacent to the cut tape 23 in an unsealing start part 30 of a side seal part 60 of the bag body. The easily unsealable structure 50 may be formed by: forming a hole portion 50a or a portion formed by a weak line on the mounting base part 212, arranging a thickness of the mounting base part 212 in the unsealing start part 30 so as to be thinner than other portions, or forming a non-adhesive part between the mounting base part 212 and the cut tape 23.

公开(公告)号：US08820158B2

公开(公告)日：2014-09-02

申请号：US13356344

申请日：2012-01-23

申请人： Toshio Oike ,  Kenichi Tanaka

发明人： Toshio Oike ,  Kenichi Tanaka

IPC分类号： G01F23/32 ,  G01F23/36 ,  G01D5/165 ,  G01F23/00

CPC分类号： G01D5/165 ,  G01F23/363

摘要： A liquid level detecting device includes a resistor plate having conductive segments, a float that vertically moves in accordance with a displacement of a liquid level, a float arm that has one end to which the float is attached and the other end which is rotatably supported so as to be rotated in association with a vertical movement of the float, and a contact point that slides on the conductive segments in association with a rotation of the float arm. Each of the conductive segments is formed of a first metallic material and a second metallic material. The first metallic material has silver (Ag) and palladium (Pd) and the second metallic material has gold (Au) as a main component. A part which is to be brought into contact with the contact point in each of the conductive segments is formed of the second metallic material.

摘要翻译： 液面检测装置包括具有导电段的电阻板，根据液位的位移而垂直移动的浮子，具有浮子附着的一端的浮臂和可旋转地支撑的另一端 与浮子的垂直运动相关联地旋转，以及与浮动臂的旋转相关联地在导电段上滑动的接触点。 每个导电段由第一金属材料和第二金属材料形成。 第一金属材料具有银（Ag）和钯（Pd），第二金属材料具有金（Au）作为主要成分。 要与每个导电段中的接触点接触的部分由第二金属材料形成。

公开(公告)号：US08671751B2

公开(公告)日：2014-03-18

申请号：US13355816

申请日：2012-01-23

申请人： Takafumi Shimizu ,  Toshio Oike ,  Kenichi Tanaka

发明人： Takafumi Shimizu ,  Toshio Oike ,  Kenichi Tanaka

IPC分类号： G01F23/32 ,  G01F23/00

CPC分类号： H01C10/16 ,  G01F23/36 ,  H01C10/32

摘要： A liquid level detecting apparatus is provided. A resistance plate has a plurality of elongated conductive segments arranged therein. A float is configured to be moved upward and downward depending on a displacement of a liquid level to be measured. A floating arm has one end attached to the float and the other end rotatably supported to be rotated in response to upward and downward movements of the float. A contact is configured to be slid on the plurality of conductive segments in association with a rotation of the float arm depending on the liquid level. The plurality of conductive segments comprise a plurality of first segments made of a first metal material containing at least silver (Ag) and palladium (Pd), and a plurality of second segments made of a second metal material essentially containing gold (Au).

摘要翻译： 提供了液面检测装置。 电阻板具有布置在其中的多个细长导电段。 浮子被配置为根据要测量的液位的位移而向上和向下移动。 浮动臂具有一端连接到浮子，另一端可自由旋转地支撑，以响应浮子的向上和向下运动而旋转。 触点构造成根据液面而与浮动臂的旋转相关联地在多个导电段上滑动。 多个导电段包括由至少含有银（Ag）和钯（Pd）的第一金属材料制成的多个第一段和由基本上含有金（Au）的第二金属材料制成的多个第二段。

公开(公告)号：US08540428B2

公开(公告)日：2013-09-24

申请号：US12442204

申请日：2007-06-27

申请人： Yoshinori Nanba ,  Kenichi Tanaka ,  Shuichi Goto

发明人： Yoshinori Nanba ,  Kenichi Tanaka ,  Shuichi Goto

IPC分类号： B65D65/28

CPC分类号： B65D33/2508 ,  B29C65/02 ,  B29C66/1122 ,  B29C66/3452 ,  B29C66/346 ,  B29C66/43121 ,  B29C66/474 ,  B29C66/71 ,  B29C66/72321 ,  B29C66/72325 ,  B29C66/72341 ,  B29C66/80 ,  B29C66/81422 ,  B29C66/81423 ,  B29C66/81427 ,  B29C66/81431 ,  B29C66/83221 ,  B29D5/10 ,  B29K2023/00 ,  B29K2023/06 ,  B29K2023/0625 ,  B29K2023/0633 ,  B29K2023/086 ,  B29K2023/12 ,  B29K2027/08 ,  B29K2033/20 ,  B29K2067/00 ,  B29K2101/12 ,  B29K2305/02 ,  B29K2995/0053 ,  B29K2995/0067 ,  B29L2005/00 ,  B29L2009/003 ,  B29L2031/7128 ,  B31B70/642 ,  B31B70/8132 ,  B65D33/2533 ,  B65D33/2541 ,  B65D75/5805 ,  Y10T29/49 ,  Y10T29/51 ,  B29K2077/00 ,  B29K2067/006 ,  B29K2067/003 ,  B29K2025/06

摘要： A belt-shaped base of a male member of a zipper tape attached to an inner surface of a bag body includes: a main body on which an engagement portion is provided; a first projecting portion provided on an opening-side of the main body; a thin portion connected to an opening-side of the first projecting portion; and a second projecting portion connected to an opening-side of the thin portion. A belt-shaped base of a female member includes: a main body; a first projecting portion; a thin portion; and a second projecting portion. When the zipper tape is fused onto the bag body, a space is provided between the thin portions and a film of the bag body.

摘要翻译： 附着在袋体的内表面上的卡扣带的阳构件的带状基座包括：主体，设置有接合部; 设置在所述主体的开口侧的第一突出部; 与所述第一突出部的开口侧连接的薄壁部; 以及与薄部的开口侧连接的第二突出部。 阴构件的带状基座包括：主体; 第一突出部分; 一小部分 和第二突出部分。 当拉链带熔合到袋体上时，在薄片部分和袋体之间设置有空间。

公开(公告)号：US08449160B2

公开(公告)日：2013-05-28

申请号：US12849352

申请日：2010-08-03

申请人： Kenichi Tanaka ,  Masahiro Aoki ,  Tsukuru Ohtoshi

发明人： Kenichi Tanaka ,  Masahiro Aoki ,  Tsukuru Ohtoshi

IPC分类号： F21V7/04

CPC分类号： G02B6/4204 ,  G02B27/0994 ,  G02B27/1006 ,  G02B27/104 ,  G02B27/123 ,  H01S5/02212 ,  H01S5/02284 ,  H01S5/4012 ,  H01S5/4093 ,  H04N9/3129 ,  H04N9/3161

摘要： A multi-wavelength light emitting device includes the following three sections; a light source section having multiple luminous points that emit multiple light beams, a condenser lens section that concentrates the light beams emitted from the luminous points, and a light guide section that propagates superposedly and mixedly the light beams concentrated by the condenser lens section after emission thereof from the luminous points.

摘要翻译： 多波长发光器件包括以下三个部分; 具有发射多个光束的多个发光点的光源部分，聚集从发光点发射的光束的聚光透镜部分和在发射之后叠加并混合由聚光透镜部分聚集的光束的导光部分 来自发光点。

公开(公告)号：US08306301B2

公开(公告)日：2012-11-06

申请号：US13237113

申请日：2011-09-20

申请人： Kenichi Tanaka

发明人： Kenichi Tanaka

IPC分类号： G06K9/00

CPC分类号： A61B1/05 ,  A61B1/00009 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0646 ,  A61B5/489 ,  G06T7/0012 ,  G06T7/12 ,  G06T2207/10068 ,  G06T2207/30101

摘要： An image processing apparatus includes: a region detection section which detects a candidate region in which a structure having a predetermined shape is estimated to exist from an image a border pixel detection section which detects a border of the candidate region; a region setting section which sets a local region in the vicinity of and both sides of the border; a feature value calculation section which calculates predetermined feature values based on predetermined values obtained for respective pixel units of the local regions; a discrimination value calculation section which calculates a discrimination value based on calculation results of the predetermined feature values in local region groups on one side and the other side when viewed from the border; and a candidate region correction section which corrects a detection result of a candidate region based on a calculation result of the discrimination value.

摘要翻译： 一种图像处理装置，包括：区域检测部，其从检测到所述候选区域的边界的边界像素检测部的图像检测出其中存在具有预定形状的结构的候选区域; 区域设定部，其设定边界附近和两侧的局部区域; 特征值计算部，其基于针对所述局部区域的各像素单位获得的规定值来计算预定特征量; 鉴别值计算部分，当从边界观察时，基于在一侧和另一侧的局部区域组中的预定特征值的计算结果来计算鉴别值; 以及候选区域校正部，其基于所述识别值的计算结果来校正候选区域的检测结果。