公开(公告)号：US5296473A

公开(公告)日：1994-03-22

申请号：US850609

申请日：1992-03-13

申请人： Kozo Hara ,  Kohki Fujita ,  Masayuki Yamashita ,  Yasuhiko Tsunetomi ,  Shuzo Sakai ,  Toshio Miyake

发明人： Kozo Hara ,  Kohki Fujita ,  Masayuki Yamashita ,  Yasuhiko Tsunetomi ,  Shuzo Sakai ,  Toshio Miyake

IPC分类号： A23C9/156 ,  A23F5/24 ,  A23G1/00 ,  A23G1/56 ,  A23G3/34 ,  A23G4/00 ,  A23G4/10 ,  A23K1/16 ,  A23L1/187 ,  A23L1/236 ,  C12P19/18 ,  C13K13/00 ,  A61K31/70 ,  A61K31/715 ,  C12P19/04

CPC分类号： A23G4/10 ,  A23C9/156 ,  A23F5/243 ,  A23G1/56 ,  A23G3/346 ,  A23K20/163 ,  A23L27/33 ,  A23L9/10 ,  C12P19/18 ,  C12Y204/0101 ,  C12Y302/01026 ,  C13K13/00 ,  A23G2200/06 ,  Y10S435/803 ,  Y10S435/83

摘要： The lactosucrose high-content powder according to the present invention is prepared by allowing an aqueous solution containing sucrose and lactose to act on a saccharidetransferring enzyme, removing concomitant saccharides in the resultant saccharide solution containing lactosucrose to obtain a solution having a high concentration of lactosucrose, i.e. lactosucrose content of 45 w/w % or more of the sugar composition, and spraydrying the resultant solution to obtain a powder having a high concentration of lactosucrose. The powder is incorporated in an orally- or parenterally-administrable product to obtain an orally- or parenterally-administrable product which exerts a selective growth-promoting-effect on a microorganism of the genus Bifidobacterium in vivo.

摘要翻译： 根据本发明的乳糖蔗糖高含量粉末是通过使含有蔗糖和乳糖的水溶液作用于糖转移酶，除去所得到的含有蔗糖的糖溶液中的伴随糖，得到具有高浓度的乳糖蔗糖的溶液， 即乳糖蔗糖含量为糖组成的45w / w％以上，喷雾干燥所得溶液，得到乳糖浓度高的粉末。 将粉末掺入口服或肠胃外给药的产品中以获得在体内对双歧杆菌属的微生物施加选择性生长促进作用的口服或肠胃外给药的产品。

公开(公告)号：US5130239A

公开(公告)日：1992-07-14

申请号：US665828

申请日：1991-03-07

申请人： Kozo Hara ,  Kohki Fujita ,  Masayuki Yamashita ,  Yasuhiko Tsunetomi ,  Shuzo Sakai ,  Toshio Miyake

发明人： Kozo Hara ,  Kohki Fujita ,  Masayuki Yamashita ,  Yasuhiko Tsunetomi ,  Shuzo Sakai ,  Toshio Miyake

IPC分类号： A23C9/156 ,  A23F5/24 ,  A23G1/00 ,  A23G1/56 ,  A23G3/34 ,  A23G4/00 ,  A23G4/10 ,  A23K1/16 ,  A23L1/187 ,  A23L1/236 ,  C12P19/18 ,  C13K13/00

CPC分类号： A23G4/10 ,  A23C9/156 ,  A23F5/243 ,  A23G1/56 ,  A23G3/346 ,  A23K20/163 ,  A23L27/33 ,  A23L9/10 ,  C12P19/18 ,  C12Y204/0101 ,  C12Y302/01026 ,  C13K13/00 ,  A23G2200/06 ,  Y10S435/803 ,  Y10S435/83

摘要： The lactosucrose high-content powder according to the present invention is prepared by allowing an aqueous solution containing sucrose and lactose to act on a saccharide-transferring enzyme, removing concomitant saccharides in the resultant saccharide solution containing lactosucrose to obtain a lactosucrose high-content solution with a lactosucrose content of 45 w/w % or higher on sugar composition, and spray-drying the resultant solution to obtain a lactosucrose high-content powder. The powder is incorporated in an orally- or parenterally-administrable product to obtain an orally- or parenterally-administrable product which exerts a selective growth-promoting-effect on a microorganism of the genus Bifidobacterium in vivo.

公开(公告)号：US4843156A

公开(公告)日：1989-06-27

申请号：US692066

申请日：1985-01-16

申请人： Toshio Miyake ,  Shuzo Sakai ,  Takashi Shibuya

发明人： Toshio Miyake ,  Shuzo Sakai ,  Takashi Shibuya

IPC分类号： A23L27/30 ,  C07H1/06 ,  C07H3/06 ,  C13K13/00

CPC分类号： C07H3/06 ,  C13K13/005

摘要： Oligoglucosylfructosides wherein an oligoglucosylfructoside having a polymerization degree of 2 or 3 glucose units are recovered in a high purity from a feed solution additionally containing substantial amounts of higher- and lower-oligosaccharides by sequentially admitting predetermined volumes of the feed solution and water to the column of a strongly-acidic cation exchange resin in alkaline-earth metal form; sequentially separating the effluents from the column into the first fraction rich in the higher oligosaccharide, the second fraction rich in the higher oligosaccharide but highly contaiminated with the oligoglucosylfructoside, the first fraction rich in the oligoglucosylfructoside, the fourth fraction rich in the oligoglucosylfructoside but highly contaminated with the lower oligosaccharide, and the fifth fraction rich in the lower oligosaccharide; and recovering the third fraction. The second- and fourth fractions can be admitted to the column so as to decrease the amount of elution water and also to recover the high-oligoglucosylfructoside fraction in a much higher concentration and recovery yield.

摘要翻译： 其中通过依次将预定体积的进料溶液和水顺序地加入到含有大量低聚糖的进料溶液的塔中，通过另外含有大量的高级和低级寡糖的进料溶液以高纯度从高纯度回收聚合度为2或3个葡萄糖单元的寡葡糖基果糖苷 碱土金属形式的强酸性阳离子交换树脂; 将从柱中排出的污水依次分离成富含较高寡糖的第一级分，第二级分富含高寡聚物，但与寡葡糖基果糖苷高度接触，第一级富含寡聚葡糖基果糖苷，第四级富含低聚葡糖基果糖苷但高度污染 低级寡糖，第五级富含低聚糖; 并回收第三部分。 可以将第二和第四级分进入柱，以减少洗脱水的量，并且还可以以更高的浓度和回收率获得高寡葡糖基果糖苷级分。

公开(公告)号：US4816272A

公开(公告)日：1989-03-28

申请号：US133813

申请日：1987-12-16

申请人： Masakazu Mitsuhashi ,  Shuzo Sakai ,  Toshio Miyake

发明人： Masakazu Mitsuhashi ,  Shuzo Sakai ,  Toshio Miyake

IPC分类号： A23L7/109 ,  A23L1/16 ,  A23L1/236

CPC分类号： A23L7/109

摘要： Crystalline .alpha.-maltose extremely improves the stability, taste quality and shelf life of noodles and alimentary pastes, as well as decreases the addition of water in their preparation. Since crystalline .alpha.-maltose exerts an activity of binding flour, a satisfiable dough can be obtained with a reduced addition of water. In corporation of crystalline .alpha.-maltose into flour yields a premixed flour for preparing noodles and alimentary pastes, and the addition of water thereto attains an excellent dough products.

公开(公告)号：US5432161A

公开(公告)日：1995-07-11

申请号：US501900

申请日：1990-03-30

申请人： Shuzo Sakai ,  Masaru Yoneyama ,  Toshio Miyake

发明人： Shuzo Sakai ,  Masaru Yoneyama ,  Toshio Miyake

IPC分类号： C12P19/58 ,  A23L33/15 ,  A61K8/67 ,  A61K31/70 ,  A61K31/7028 ,  A61K31/7042 ,  A61K31/7048 ,  A61P3/02 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/10 ,  C07D307/62 ,  C07H15/26 ,  C07H17/04 ,  C12P19/16 ,  C12P19/18 ,  C12P19/60 ,  C07H1/00

CPC分类号： C12P19/60 ,  A61K31/7004 ,  A61K31/7024 ,  A61K8/67 ,  A61K8/676 ,  A61Q19/00 ,  A61Q19/02 ,  C07H17/04 ,  C12P19/16 ,  C12P19/18 ,  C12P19/58 ,  A61Q17/04 ,  A61Q19/10 ,  Y10S435/814 ,  Y10S435/815 ,  Y10S435/816 ,  Y10S435/913 ,  Y10S435/939 ,  Y10S514/844 ,  Y10S514/846

摘要： 2-O-.alpha.-D-Glucopyranosyl-L-ascrobic acid is crystallizable in its supersaturated solution. Crystalline 2-O-.alpha.-D-glucopyranosyl-L-ascorbic acid is substantially nonhygroscopic, free flowing, free of deliquescence, consolidation and direct reducing activity, but is readily soluble in water. Because of these characteristics, crystalline 2-O-.alpha.-D-glucopyranosyl-L-ascorbic acid is handleable with an ease, and superiorly high in stability and physiological activities. Thus, crystalline 2-O-.alpha.-D-glucopyranosyl-L-acorbic acid is favorably useful in vitamin C-enriching agents, foodstuffs, pharmaceuticals and cosmetics.

摘要翻译： 2-O-α-D-吡喃葡萄糖基-L-降血糖在其过饱和溶液中可结晶。 结晶的2-O-α-D-吡喃葡萄糖基-L-抗坏血酸是基本上不吸湿的，自由流动的，没有潮解，固化和直接还原活性，但易溶于水。 由于这些特性，结晶2-O-α-D-吡喃葡萄糖基-L-抗坏血酸易于处理，并且具有优异的稳定性和生理活性。 因此，结晶的2-O-α-D-吡喃葡萄糖基-L-抗坏血酸有利地用于维生素C富集剂，食品，药物和化妆品。

公开(公告)号：US5112407A

公开(公告)日：1992-05-12

申请号：US526958

申请日：1990-05-22

申请人： Shuzo Sakai ,  Hiroshi Akai ,  Toshio Miyake

发明人： Shuzo Sakai ,  Hiroshi Akai ,  Toshio Miyake

IPC分类号： C07H3/04 ,  C07H1/00 ,  C13K7/00

CPC分类号： C13K7/00

摘要： There is provided a process to prepare maltose powder containing crystalline beta-maltose hydrate, comprising concentrating an aqueous solution of a high-purity maltose having a maltose content of at least 85% DS to a moisture content below 10 w/w %, partially crystallizing alpha-maltose in the syrup, and crystallizing beta-maltose hydrate in the same syrup while converting the resultant crystalline alpha-maltose into crystalline beta-maltose hydrate. Use of the invention enables consistently high-quality maltose powders at a reduced drying cost.

公开(公告)号：US4870059A

公开(公告)日：1989-09-26

申请号：US870132

申请日：1986-06-03

申请人： Masakazu Mitsuhashi ,  Shuzo Sakai ,  Toshio Miyake

发明人： Masakazu Mitsuhashi ,  Shuzo Sakai ,  Toshio Miyake

IPC分类号： A23L3/3463 ,  A23L3/40 ,  A23L3/42 ,  A61K9/00 ,  A61K47/00 ,  A61K47/26 ,  B01J20/24 ,  C13K7/00 ,  F26B5/16

CPC分类号： F26B5/16 ,  A23L3/3463 ,  A23L3/42 ,  A61K47/26 ,  A61K9/0014 ,  A61K9/0019 ,  Y10S514/844 ,  Y10S514/88

摘要： There are disclosed a novel desiccant containing anhydrous maltose and dehydration of hydrous matters, e.g. food, pharmaceutical and cosmetic, therewith. Such hydrous matters are dehydrated without causing alteration or deterioration by incorporating anhydrous maltose into the hydrous matters to convert the anhydrous maltose into crystalline beta-maltose hydrate. The anhydrous maltoses usable in the invention are anhydrous crystalline alpha-maltose, anhydrous crystalline beta-maltose and anhydrous amorphous beta-maltose, specifically, those in pulverulent form.

摘要翻译： 公开了含有无水麦芽糖的新型干燥剂和水合物的脱水，例如 食品，制药和化妆品。 通过将无水麦芽糖加入到含水物质中，将无水麦芽糖转化为结晶β-麦芽糖水合物，使水合物脱水而不引起改变或变质。 可用于本发明的无水麦芽糖是无水结晶α-麦芽糖，无水结晶β-麦芽糖和无水无定形β-麦芽糖，具体是粉末形式的那些。

公开(公告)号：US5407812A

公开(公告)日：1995-04-18

申请号：US150981

申请日：1993-11-12

申请人： Shuzo Sakai ,  Masaru Yoneyama ,  Toshio Miyake

发明人： Shuzo Sakai ,  Masaru Yoneyama ,  Toshio Miyake

IPC分类号： C12P19/58 ,  A23L33/15 ,  A61K8/67 ,  A61K31/70 ,  A61K31/7028 ,  A61K31/7042 ,  A61K31/7048 ,  A61P3/02 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/10 ,  C07D307/62 ,  C07H15/26 ,  C07H17/04 ,  C12P19/16 ,  C12P19/18 ,  C12P19/60

CPC分类号： C12P19/60 ,  A61K31/7004 ,  A61K31/7024 ,  A61K8/67 ,  A61K8/676 ,  A61Q19/00 ,  A61Q19/02 ,  C07H17/04 ,  C12P19/16 ,  C12P19/18 ,  C12P19/58 ,  A61Q17/04 ,  A61Q19/10 ,  Y10S435/814 ,  Y10S435/815 ,  Y10S435/816 ,  Y10S435/913 ,  Y10S435/939 ,  Y10S514/844 ,  Y10S514/846

摘要： 2-O-.alpha.-D-Glucopyranosyl-L-ascrobic acid is crystallizable in its supersaturated solution. Crystalline 2-O-.alpha.-D-glucopyranosyl-L-ascorbic acid is substantially nonhygroscopic, free flowing, free of deliquescence, consolidation and direct reducing activity, but is readily soluble in water. Because of these, characteristics crystalline 2-O-.alpha.-D-glucopyranosyl-L-ascorbic acid is handleable with an ease, and superiorly high in stability and physiological activities. Thus, crystalline 2-O-.alpha.-D-glucopyranosyl-L-ascorbic acid is favorably useful in vitamin C-enriching agents, foodstuffs, pharmaceuticals and cosmetics.

摘要翻译： 2-O-α-D-吡喃葡萄糖基-L-降血糖在其过饱和溶液中可结晶。 结晶的2-O-α-D-吡喃葡萄糖基-L-抗坏血酸是基本上不吸湿的，自由流动的，没有潮解，固化和直接还原活性，但易溶于水。 因此，具有结晶2-O-α-D-吡喃葡萄糖基-L-抗坏血酸的特征易于处理，并且具有优异的稳定性和生理活性。 因此，结晶的2-O-α-D-吡喃葡萄糖基-L-抗坏血酸有利地用于维生素C富集剂，食品，药物和化妆品。

公开(公告)号：US4812444A

公开(公告)日：1989-03-14

申请号：US942421

申请日：1986-12-16

申请人： Masakazu Mitsuhashi ,  Shuzo Sakai ,  Toshio Miyake

发明人： Masakazu Mitsuhashi ,  Shuzo Sakai ,  Toshio Miyake

IPC分类号： B01J20/22 ,  A21D10/00 ,  A23C9/123 ,  A23C15/14 ,  A23G3/34 ,  A23L1/00 ,  A23L1/03 ,  A23L1/09 ,  A23L1/10 ,  A23L1/202 ,  A23L1/238 ,  A23L1/24 ,  A23L1/32 ,  A23L1/326 ,  A23L3/3463 ,  A23L3/40 ,  A23L3/42 ,  A61K8/60 ,  A61K9/00 ,  A61K35/00 ,  A61K36/00 ,  A61K38/00 ,  A61K38/16 ,  A61K38/21 ,  A61K45/06 ,  A61K47/00 ,  A61K47/26 ,  A61P3/02 ,  A61Q19/00 ,  C08L5/00 ,  F26B5/16

CPC分类号： F26B5/16 ,  A23L3/3463 ,  A23L3/42 ,  A61K47/26 ,  A61K8/60 ,  A61K9/0014 ,  A61K9/0019 ,  A61Q19/00 ,  A61Q11/00 ,  A61Q5/00

摘要： A novel dehydration method using anhydrous glycosylfructose as the desiccant is disclosed. Anhydrous glycosylfructose is converted to the crystalline hydrate and acts as the desiccant when incorporated into a hydrous matter. Natural saccharides such as palatinose, raffinose, erlose, and melezitose can be used. The dehydration is applicable to hydrous matters, such as those of foods, pharmaceuticals, cosmetics, and their materials and intermediates.

摘要翻译： 公开了一种使用无水糖果果糖作为干燥剂的新型脱水方法。 将无水糖果果糖转化为结晶水合物，并且当掺入含水物质中时用作干燥剂。 可以使用天然糖类，如帕拉金糖，棉子糖，埃洛尔和松三糖。 脱水适用于食品，药品，化妆品及其材料和中间体等含水物质。

公开(公告)号：US4810827A

公开(公告)日：1989-03-07

申请号：US942423

申请日：1986-12-16

申请人： Masakazu Mitsuhashi ,  Shuzo Sakai ,  Toshio Miyake

发明人： Masakazu Mitsuhashi ,  Shuzo Sakai ,  Toshio Miyake

IPC分类号： B01J20/22 ,  A21D10/00 ,  A23C9/123 ,  A23C13/12 ,  A23C15/12 ,  A23C15/14 ,  A23G3/34 ,  A23L1/00 ,  A23L1/03 ,  A23L1/09 ,  A23L1/10 ,  A23L1/202 ,  A23L1/238 ,  A23L1/24 ,  A23L1/32 ,  A23L1/326 ,  A23L3/3463 ,  A23L3/40 ,  A23L3/42 ,  A61K9/70 ,  A61K35/00 ,  A61K36/00 ,  A61K38/00 ,  A61K38/16 ,  A61K38/21 ,  A61K45/06 ,  A61K47/00 ,  A61K47/26 ,  A61P3/02 ,  F26B5/16 ,  C08L5/00

CPC分类号： F26B5/16 ,  A23L3/3463 ,  A23L3/42

摘要： A novel dehydration process using anhydrous aldohexose as the desiccant is disclosed. Anhydrous aldohexose is converted to crystalline hydrate and acts as the desiccant when it is incorporated into a hydrous substance. Natural saccharides such as glucose, galactose, and mannose are suitable for the aldohexose. The dehydration is applicable to hydrous matters, such as those of foods, pharmaceuticals, cosmetics, and their materials and intermediates.

摘要翻译： 公开了一种使用无水己糖作为干燥剂的新型脱水方法。 将无水己糖转化为结晶水合物，并将其作为干燥剂加入含水物质中。 天然糖如葡萄糖，半乳糖和甘露糖适用于己糖糖。 脱水适用于食品，药品，化妆品及其材料和中间体等含水物质。