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1.发明授权Microorganism for producing riboflavin and method for producing riboflavin using the same 有权用于生产核黄素的微生物及使用其生产核黄素的方法公开(公告)号：US07166456B2
公开(公告)日：2007-01-23
申请号：US10454221
申请日：2003-06-04
申请人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
发明人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
摘要： Riboflavin-producing Bacillus subtilis which is resistant to proline analogue, and a method for producing riboflavin using the Bacillus subtilis are provided.
摘要翻译： 提供了对脯氨酸类似物具有抗性的产生核黄素的枯草芽孢杆菌，以及使用枯草芽孢杆菌生产核黄素的方法。
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2.发明授权Microorganism for producing riboflavin and method for producing riboflavin using the same 有权用于生产核黄素的微生物及使用其生产核黄素的方法公开(公告)号：US07078222B2
公开(公告)日：2006-07-18
申请号：US10454220
申请日：2003-06-04
申请人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
发明人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
摘要： Riboflavin-producing Bacillus subtilis which is resistant to threonine analogue, and a method for producing riboflavin using the Bacillus subtilis are provided.The subject Bacillus subtilis referred to as Bacillus subtilis CJKB0002 has the accession number KCCM-10446, having been deposited in Korean Culture Center of Microorganisms (KCCM), 361-221, Yurim B/D, Hongie-1-dong, Seodaemun-gut, Seoul 120-091 Republic of Korea, on Nov. 18, 2002.
摘要翻译： 提供了对苏氨酸类似物具有抗性的产生核黄素的枯草芽孢杆菌，以及使用枯草芽孢杆菌生产核黄素的方法。 被称为枯草芽孢杆菌CJKB0002的枯草芽孢杆菌具有保藏在韩国微生物培养中心（KCCM），361-221，Yurim B / D，Hongie-1-dong，Seodaemun-gut的登录号KCCM-10446， 汉城120-091大韩民国，2002年11月18日。
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3.发明授权Genetically engineered recombinant Escherichia coli producing L-tryptophan having originally L-phenylalanine productivity, and method for producing L-tryptophan using the microorganism 有权生产L-苯丙氨酸生产力的基因工程重组大肠杆菌生产L-色氨酸，以及使用该微生物生产L-色氨酸的方法公开(公告)号：US08945907B2
公开(公告)日：2015-02-03
申请号：US12520350
申请日：2007-12-28
申请人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
发明人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
CPC分类号： C12P13/227 , C12N9/88 , C12N15/52
摘要： The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinant E. coli strain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) of E. coli having L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.
摘要翻译： 本发明涉及具有L-色氨酸生产力的微生物和使用其的L-色氨酸的生产方法。 更准确地说，本发明涉及由具有L-苯丙氨酸生产力的大肠杆菌的突变形式（KFCC 10066）产生的具有色氨酸生产力的重组大肠杆菌菌株CJ600（KCCM 10812P），其中色氨酸营养缺陷型被释放，L-苯丙氨酸 生物合成被阻断，但通过加强色氨酸生物合成中涉及的基因来增强色氨酸的生产力，以及使用其生产L-色氨酸的方法。
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公开(公告)号：US08569066B2
公开(公告)日：2013-10-29
申请号：US13548044
申请日：2012-07-12
申请人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
发明人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
CPC分类号： C12P13/227 , C12N9/88 , C12N15/52
摘要： The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinant E. coli strain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) of E. coli having L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.
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5.发明申请GENETICALLY ENGINEERED RECOMBINANT ESCHERICHIA COLI PRODUCING L-TRYPTOPHAN HAVING ORIGINALLY L-PHENYLALANINE PRODUCTIVITY, AND METHOD FOR PRODUCING L-TRYPTOPHAN USING THE MICROORGANISM 有权具有原始L-苯丙氨酸生产力的基因工程重组蛋白生产L-酪氨酸的方法和使用微生物生产L-酪氨酸的方法公开(公告)号：US20120276639A1
公开(公告)日：2012-11-01
申请号：US13548044
申请日：2012-07-12
申请人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
发明人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
IPC分类号： C12N15/70
CPC分类号： C12P13/227 , C12N9/88 , C12N15/52
摘要： The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinant E. coli strain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) of E. coli having L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.
摘要翻译： 本发明涉及具有L-色氨酸生产力的微生物和使用其的L-色氨酸的生产方法。 更准确地说，本发明涉及由具有L-苯丙氨酸生产力的大肠杆菌的突变形式（KFCC 10066）产生的具有色氨酸生产力的重组大肠杆菌菌株CJ600（KCCM 10812P），其中色氨酸营养缺陷型被释放，L-苯丙氨酸 生物合成被阻断，但通过加强色氨酸生物合成中涉及的基因来增强色氨酸的生产力，以及使用其生产L-色氨酸的方法。
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6.发明申请GENETICALLY ENGINEERED RECOMBINANT ESCHERICHIA COLI PRODUCING L-TRYPTOPHAN HAVING ORIGINALLY L-PHENYLALANINE PRODUCTIVITY, AND METHOD FOR PRODUCING L-TRYPTOPHAN USING THE MICROORGANISM 有权具有原始L-苯丙氨酸生产力的基因工程重组蛋白生产L-酪氨酸的方法和使用微生物生产L-酪氨酸的方法公开(公告)号：US20100028956A1
公开(公告)日：2010-02-04
申请号：US12520350
申请日：2007-12-28
申请人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
发明人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
CPC分类号： C12P13/227 , C12N9/88 , C12N15/52
摘要： The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinant E. coli strain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) of E. coli having L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.
摘要翻译： 本发明涉及具有L-色氨酸生产力的微生物和使用其的L-色氨酸的生产方法。 更准确地说，本发明涉及由具有L-苯丙氨酸生产力的大肠杆菌的突变形式（KFCC 10066）产生的具有色氨酸生产力的重组大肠杆菌菌株CJ600（KCCM 10812P），其中色氨酸营养缺陷型被释放，L-苯丙氨酸 生物合成被阻断，但通过加强色氨酸生物合成中涉及的基因来增强色氨酸的生产力，以及使用其生产L-色氨酸的方法。
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7.发明授权Avirulent Salmonella gallinarum variants and pharmaceutical composition using the same 有权无毒性沙门氏菌变种和使用其的药物组合物公开(公告)号：US08481052B2
公开(公告)日：2013-07-09
申请号：US13274854
申请日：2011-10-17
申请人： Hyang Choi , Soo An Shin , Si Yong Yang , Young Wook Cho
发明人： Hyang Choi , Soo An Shin , Si Yong Yang , Young Wook Cho
IPC分类号： A61K39/112 , C12N1/20
CPC分类号： A61K39/0275 , A61K2039/522 , A61K2039/552 , C07K14/255 , Y02A50/482
摘要： The present invention relates to avirulent Salmonella gallinarum variants by inactivating virulence gene clusters of Salmonella gallinarum (SG), a main pathogen of avian salmonellosis, and various uses thereof notably in the production of Salmonella-specific lytic bacteriophages, pharmaceutical compositions and feed additives.
摘要翻译： 本发明涉及无毒性沙门氏菌变种，其通过灭活禽沙门氏菌病的主要病原体沙门氏菌（SG）的毒力基因簇，以及其在沙门氏菌特异性溶解性噬菌体，药物组合物和饲料添加剂的生产中的各种用途。
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公开(公告)号：US08148131B2
公开(公告)日：2012-04-03
申请号：US12550304
申请日：2009-08-28
申请人： In Hye Kang , Min Tae Park , Young Wook Cho , Hyang Choi , Soo An Shin
发明人： In Hye Kang , Min Tae Park , Young Wook Cho , Hyang Choi , Soo An Shin
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , A61K2035/11 , C07K14/005 , C12N2795/10321 , C12N2795/10322
摘要： The present invention relates to a novel bacteriophage, more particularly, a bacteriophage that has a specific bactericidal activity against Fowl Typhoid causing Salmonella Gallinarum (SG) and Pullorum disease-causing Salmonella Pullorum (SP). Further, the present invention relates to a composition for the prevention or treatment of infectious diseases caused by Salmonella Gallinarum or Salmonella Pullorum, comprising the bacteriophage as an active ingredient. Furthermore, the present invention relates to feed and drinking water for poultry, sanitizers and cleaners, comprising the bacteriophage as an active ingredient.
摘要翻译： 本发明涉及一种新型的噬菌体，更具体地说，涉及一种对引起沙门氏菌（SG）和引致白血病致病沙门氏菌沙门氏菌（SP）的家禽伤寒具有特异杀菌活性的噬菌体。 此外，本发明涉及用于预防或治疗由沙门氏菌（Salmonella Gallinarum）或者沙门氏菌（Salmonella Pullorum）引起的感染性疾病的组合物，其包含噬菌体作为活性成分。 此外，本发明涉及包含噬菌体作为活性成分的家禽，消毒剂和清洁剂的饲料和饮用水。
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公开(公告)号：US20100158870A1
公开(公告)日：2010-06-24
申请号：US12560263
申请日：2009-09-15
申请人： In Hye Kang , Min Tae Park , Young Wook Cho , Soo An Shin , Hyang Choi
发明人： In Hye Kang , Min Tae Park , Young Wook Cho , Soo An Shin , Hyang Choi
CPC分类号： A61K35/76 , A23K10/16 , A23K50/75 , C12N2795/10332
摘要： The present invention relates to a novel bacteriophage, more particularly, a bacteriophage that has a specific bactericidal activity against Salmonella typhimurium, Salmonella gallinarum, or Salmonella pullorum, a composition for the prevention or treatment of infectious diseases including salmonellosis and Salmonella food poisoning caused by Salmonella typhimurium, Fowl typhoid caused by Salmonella gallinarum, and Pullorum disease caused by Salmonella pullorum, which comprises the bacteriophage as an active ingredient, and an animal feed, drinking water, cleaner, and sanitizer which comprise the bacteriophage as an active ingredient.
摘要翻译： 本发明涉及一种新的噬菌体，更具体地说，涉及对鼠伤寒沙门氏菌，沙门氏菌或沙门氏菌具有特异杀菌活性的噬菌体，用于预防或治疗由沙门氏菌引起的沙门氏菌病和沙门氏菌食物中毒的传染病的组合物 鼠伤寒沙门氏菌引起的家禽伤寒，以及包含噬菌体作为活性成分的沙门氏菌引起的白花病，以及包含噬菌体作为活性成分的动物饲料，饮用水，清洁剂和消毒剂。
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公开(公告)号：US09890404B2
公开(公告)日：2018-02-13
申请号：US13992242
申请日：2011-12-08
申请人： Hyang Choi , Kyoung Min Lee , Min Sun Kang , Sung Hoo Jhon , Hye Won Um , Su Jin Choi , Han Won Lee , Soo An Shin
发明人： Hyang Choi , Kyoung Min Lee , Min Sun Kang , Sung Hoo Jhon , Hye Won Um , Su Jin Choi , Han Won Lee , Soo An Shin
CPC分类号： C12P13/001 , C07K14/34 , C12N9/0008 , C12N9/1018 , C12N9/1029 , C12N9/1096 , C12N9/1217 , C12N9/88 , C12R1/15 , C12Y102/01038 , C12Y201/03003 , C12Y203/01035 , C12Y206/01013 , C12Y207/02008 , C12Y401/01017
摘要： The present invention relates to a putrescine-producing microorganism and a method for producing putrescine using the same. To be more specific, the present invention is directed to a microorganism given the ability to produce putrescine which is generated by blocking a biosynthetic pathway from ornithine to arginine, increasing the intracellular level of glutamate, enhancing the biosynthetic pathway of ornithine from glutamate, and introducing extracellular ornithine decarboxylase; and a method for producing putrescine by using the microorganism.
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