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    Sensitivity enhanced biomolecule field effect transistor
    1.
    发明申请
    Sensitivity enhanced biomolecule field effect transistor 有权
    灵敏度增强的生物分子场效应晶体管

    公开(公告)号：US20050199917A1

    公开(公告)日：2005-09-15

    申请号：US11057642

    申请日：2005-02-14

    Applicant: Kyu-tae Yoo ,  Geun-bae Lim ,  Joon-ho Kim ,  Kak Namkoong

    Inventor： Kyu-tae Yoo ,  Geun-bae Lim ,  Joon-ho Kim ,  Kak Namkoong

    IPC: G01N27/327 ,  C12Q1/68 ,  G01N27/414 ,  G01N33/487 ,  H01L29/08

    CPC classification number: G01N27/4145

    Abstract: There is provided a biomolecule FET enhancing a sensitivity. The biomolecule FET includes a substrate, first and second impurity regions formed on both sides of the substrate, and doped with impurities of a polarity opposite to that of the substrate, a gate formed on the substrate and being in contact with the first and second impurity regions, and a probe biomolecule attached to the gate. A region of the gate adjacent to the first impurity region is wider than a region thereof adjacent to the second impurity region. A density of the probe biomolecule attached to the surface of the gate is increased, and when detecting a level of hybridization of the probe biomolecule and the target biomolecule, its sensitivity is improved.

    Abstract translation: 提供了提高灵敏度的生物分子FET。 生物分子FET包括基板，形成在基板两侧的第一和第二杂质区，并且掺杂极性与基板极性相反的杂质;形成在基板上并与第一和第二杂质接触的栅极 区域，以及连接到门的探针生物分子。 与第一杂质区相邻的栅极的区域比与第二杂质区相邻的区域宽。 附着在栅极表面的探针生物分子的密度增加，并且当检测到探针生物分子和靶生物分子的杂交水平时，其灵敏度得到改善。

    Sensitivity enhanced biomolecule field effect transistor
    2.
    发明授权
    Sensitivity enhanced biomolecule field effect transistor 有权
    灵敏度增强的生物分子场效应晶体管

    公开(公告)号：US07151301B2

    公开(公告)日：2006-12-19

    申请号：US11057642

    申请日：2005-02-14

    Applicant: Kyu-tae Yoo ,  Geun-bae Lim ,  Joon-ho Kim ,  Kak Namkoong

    Inventor： Kyu-tae Yoo ,  Geun-bae Lim ,  Joon-ho Kim ,  Kak Namkoong

    IPC: H01L29/76

    CPC classification number: G01N27/4145

    Abstract: There is provided a biomolecule FET enhancing a sensitivity. The biomolecule FET includes a substrate, first and second impurity regions formed on both sides of the substrate, and doped with impurities of a polarity opposite to that of the substrate, a gate formed on the substrate and being in contact with the first and second impurity regions, and a probe biomolecule attached to the gate. A region of the gate adjacent to the first impurity region is wider than a region thereof adjacent to the second impurity region. A density of the probe biomolecule attached to the surface of the gate is increased, and when detecting a level of hybridization of the probe biomolecule and the target biomolecule, its sensitivity is improved.

    Abstract translation: 提供了提高灵敏度的生物分子FET。 生物分子FET包括基板，形成在基板两侧的第一和第二杂质区，并且掺杂极性与基板极性相反的杂质;形成在基板上并与第一和第二杂质接触的栅极 区域，以及连接到门的探针生物分子。 与第一杂质区相邻的栅极的区域比与第二杂质区相邻的区域宽。 附着在栅极表面的探针生物分子的密度增加，并且当检测到探针生物分子和靶生物分子的杂交水平时，其灵敏度得到改善。

    Biomolecule sensing method using Field Effect Transistor with controllable Debye length
    3.
    发明申请
    Biomolecule sensing method using Field Effect Transistor with controllable Debye length 审中-公开
    使用可控德拜长度的场效应晶体管的生物分子感测方法

    公开(公告)号：US20050191683A1

    公开(公告)日：2005-09-01

    申请号：US11063214

    申请日：2005-02-22

    Applicant: Kyu-tae Yoo ,  Geun-bae Lim

    Inventor： Kyu-tae Yoo ,  Geun-bae Lim

    IPC: G01N27/327 ,  C12Q1/68 ,  G01N33/543

    CPC classification number: G01N33/54373

    Abstract: A method of sensing biomolecules in an electrolyte solution by using a bio FET. When it is sensed that probe biomolecules are immobilized to a gate surface of the bio FET or that the probe biomolecules are hybridized with target biomolecules, a Debye length from the biomolecules having charges attached to the gate surface is controlled.

    Abstract translation: 通过使用生物FET感测电解质溶液中的生物分子的方法。 当感测到探针生物分子被固定在生物FET的栅极表面上或者探针生物分子与靶生物分子杂交时，来自具有连接到栅极表面的电荷的生物分子的德拜长度受到控制。

    Sensing switch and detecting method using the same
    6.
    发明授权
    Sensing switch and detecting method using the same 失效
    感应开关及使用其的检测方法

    公开(公告)号：US07510865B2

    公开(公告)日：2009-03-31

    申请号：US11347185

    申请日：2006-02-03

    Applicant: Kyu-tae Yoo ,  Joon-ho Kim ,  Jun-hong Min ,  Sung-ouk Jung ,  Ji-na Namgoong ,  Kui-hyun Kim ,  Jeo-young Shim ,  Kak Namkoong

    Inventor： Kyu-tae Yoo ,  Joon-ho Kim ,  Jun-hong Min ,  Sung-ouk Jung ,  Ji-na Namgoong ,  Kui-hyun Kim ,  Jeo-young Shim ,  Kak Namkoong

    IPC: C12M1/34

    CPC classification number: G01N33/54373

    Abstract: Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.

    Abstract translation: 提供了一种感测开关和使用该感测开关的感测方法。 感测开关包括：基板; 底物上的支撑物; 感测板，其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时，引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极，并且当感测板由于感测板的偏转而与基板接触时被连接。 目标材料不需要标注，不需要使用分析装置的荧光或电检测信号的信号处理，并且可以通过确认电流是否流过开关直接解码信号。

    Method and apparatus for providing blood glucose management information
    8.
    发明授权
    Method and apparatus for providing blood glucose management information 有权
    用于提供血糖管理信息的方法和装置

    公开(公告)号：US08974385B2

    公开(公告)日：2015-03-10

    申请号：US12824344

    申请日：2010-06-28

    Applicant: Kwang-hyeon Lee ,  Kyu-tae Yoo

    Inventor： Kwang-hyeon Lee ,  Kyu-tae Yoo

    IPC: A61B5/00 ,  G06F19/00 ,  A61B5/145

    CPC classification number: G06F19/3443 ,  A61B5/14532 ,  G06F19/00 ,  G06F19/3418 ,  G16H50/70

    Abstract: An apparatus and method of providing blood glucose management information includes a determination unit that determines a similarity of a blood glucose change pattern of a user by comparing blood glucose information obtained from the user and stored blood glucose information, an extraction unit that extracts at least one piece of blood glucose information from the stored blood glucose information according to the similarity and generates extracted blood glucose information, and an interface unit which provides the blood glucose management information, which corresponds to the extracted blood glucose information, to the user.

    Abstract translation: 提供血糖管理信息的装置和方法包括：确定单元，其通过比较从用户获得的血糖信息和存储的血糖信息来确定用户的血糖变化模式的相似性;提取单元，其提取至少一个 根据相似度从所存储的血糖信息中提取血糖信息，并产生提取的血糖信息，以及向用户提供与提取的血糖信息相对应的血糖管理信息的接口单元。

    FET-type biosensor with surface modification
    9.
    发明授权
    FET-type biosensor with surface modification 有权
    具有表面改性的FET型生物传感器

    公开(公告)号：US08735077B2

    公开(公告)日：2014-05-27

    申请号：US11336110

    申请日：2006-01-20

    Applicant: Jeo-young Shim ,  Su-hyeon Kim ,  Kyu-tae Yoo ,  Sung-ouk Jung ,  Joon-shik Park

    Inventor： Jeo-young Shim ,  Su-hyeon Kim ,  Kyu-tae Yoo ,  Sung-ouk Jung ,  Joon-shik Park

    IPC: G01N33/53

    CPC classification number: B82Y30/00 ,  B82Y15/00 ,  G01N27/4145

    Abstract: Provided is a field effect transistor (FET) type biosensor including a source electrode, a gate, and a drain electrode. A ligand that can bind to a side of a nucleic acid is added to the surface of the gate. In a conventional FET type biosensor, it is difficult to detect a signal within the debye length because a target nucleic acid is directly fixed to the surface of a gate of the conventional FET. However, in the present invention, this problem can be overcome and the debye length can be increased by treating the surface of a gate of an FET sensor with a ligand that can bind to a side of a nucleic acid. The ligand can be adsorbed onto the surface of the gate. In this case, the nucleic acid is adsorbed parallel to the surface of the gate, not perpendicular to the surface of the gate, thus generating an effective depletion region. In addition, hybridization efficiency can be increased because a hybridized sample can be injected into an FET sensor at high ionic strength.

    Abstract translation: 提供了包括源电极，栅极和漏电极的场效应晶体管（FET）型生物传感器。 可以结合核酸一侧的配体加入到门的表面。 在传统的FET型生物传感器中，由于目标核酸直接固定在常规FET的栅极表面，难以检测德拜长度内的信号。 然而，在本发明中，可以克服这个问题，并且可以通过用可以结合核酸一侧的配体处理FET传感器的栅极的表面来增加德拜长度。 配体可以吸附在栅极的表面上。 在这种情况下，核酸被平行于栅极的表面吸附，而不垂直于栅极的表面，从而产生有效的耗尽区域。 此外，杂交效率可以提高，因为杂化样品可以以高离子强度注入FET传感器。

    System and method of sharing web page that represents health information
    10.
    发明授权
    System and method of sharing web page that represents health information 有权
    共享代表健康信息的网页的系统和方法

    公开(公告)号：US08700889B2

    公开(公告)日：2014-04-15

    申请号：US12757189

    申请日：2010-04-09

    Applicant: Kwang-hyeon Lee ,  Kyu-tae Yoo

    Inventor： Kwang-hyeon Lee ,  Kyu-tae Yoo

    IPC: H04L29/06 ,  H04L9/32 ,  G06F7/04 ,  G06F15/16 ,  G06F17/30

    CPC classification number: G06F19/3418 ,  G06F19/00

    Abstract: A method of displaying health information of a user, the method including: monitoring if a sharing request for a health information of a user is made by an external device, which provides a web page representing the health information of the user in the form of an image; downloading a captured image of the web page from the external device if the sharing request for the health information of the user is made; and displaying the downloaded captured image.

    Abstract translation: 一种显示用户的健康信息的方法，所述方法包括：监视用户的健康信息的共享请求是否由外部设备进行，所述外部设备提供表示用户形式的用户的健康信息的网页 图片; 如果对用户的健康信息进行共享请求，则从外部设备下载捕获的网页图像; 并显示下载的捕获图像。

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