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23 条记录 (耗时 0.032 秒)

    SENSING SWITCH AND DETECTING METHOD USING THE SAME
    5.
    发明申请
    SENSING SWITCH AND DETECTING METHOD USING THE SAME 有权
    感应开关及其检测方法

    公开(公告)号：US20100329931A1

    公开(公告)日：2010-12-30

    申请号：US12833095

    申请日：2010-07-09

    申请人： Kyu-tae YOO ,  Joon-ho KIM ,  Jun-hong MIN ,  Sung-ouk JUNG ,  Ji-na NAMGOONG ,  Kui-hyun KIM ,  Jeo-young SHIM ,  Kak NAMKOONG

    发明人： Kyu-tae YOO ,  Joon-ho KIM ,  Jun-hong MIN ,  Sung-ouk JUNG ,  Ji-na NAMGOONG ,  Kui-hyun KIM ,  Jeo-young SHIM ,  Kak NAMKOONG

    IPC分类号： G01N27/00

    CPC分类号： G01N33/54373

    摘要： Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.

    摘要翻译： 提供了一种感测开关和使用该感测开关的感测方法。 感测开关包括：基板; 底物上的支撑物; 感测板，其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时，引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极，并且当感测板由于感测板的偏转而与基板接触时被连接。 目标材料不需要标注，不需要使用分析装置的荧光或电检测信号的信号处理，并且可以通过确认电流是否流过开关直接解码信号。

    SENSING SWITCH AND DETECTING METHOD USING THE SAME
    6.
    发明申请
    SENSING SWITCH AND DETECTING METHOD USING THE SAME 有权
    感应开关及其检测方法

    公开(公告)号：US20090170211A1

    公开(公告)日：2009-07-02

    申请号：US12272183

    申请日：2008-11-17

    申请人： Kyu-tae YOO ,  Joon-ho KIM ,  Jun-hong MIN ,  Sung-ouk JUNG ,  Ji-na NAMGOONG ,  Kui-hyun KIM ,  Jeo-young SHIM ,  Kak NAMKOONG

    发明人： Kyu-tae YOO ,  Joon-ho KIM ,  Jun-hong MIN ,  Sung-ouk JUNG ,  Ji-na NAMGOONG ,  Kui-hyun KIM ,  Jeo-young SHIM ,  Kak NAMKOONG

    IPC分类号： G01N27/00

    CPC分类号： G01N33/54373

    摘要： Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.

    摘要翻译： 提供了一种感测开关和使用该感测开关的感测方法。 感测开关包括：基板; 底物上的支撑物; 感测板，其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时，引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极，并且当感测板由于感测板的偏转而与基板接触时被连接。 目标材料不需要标注，不需要使用分析装置的荧光或电检测信号的信号处理，并且可以通过确认电流是否流过开关直接解码信号。

    FET-BASED SENSOR FOR DETECTING IONIC MATERIAL, IONIC MATERIAL DETECTING DEVICE USING THE FET-BASED SENSOR, AND METHOD OF DETECTING IONIC MATERIAL USING THE FET-BASED SENSOR
    7.
    发明申请
    FET-BASED SENSOR FOR DETECTING IONIC MATERIAL, IONIC MATERIAL DETECTING DEVICE USING THE FET-BASED SENSOR, AND METHOD OF DETECTING IONIC MATERIAL USING THE FET-BASED SENSOR 有权
    用于检测离子材料的基于FET的传感器，使用基于FET的传感器的离子材料检测装置以及使用基于FET的传感器检测离子材料的方法

    公开(公告)号：US20110043213A1

    公开(公告)日：2011-02-24

    申请号：US12912191

    申请日：2010-10-26

    申请人： Kyu-sang LEE ,  Kyu-tae YOO ,  Jeo-young SHIM ,  Jin-tae KIM ,  Yeon-ja CHO

    发明人： Kyu-sang LEE ,  Kyu-tae YOO ,  Jeo-young SHIM ,  Jin-tae KIM ,  Yeon-ja CHO

    IPC分类号： G01N27/62

    CPC分类号： G01N33/54373 ,  C12Q1/6825 ,  G01N27/4145

    摘要： Provided are a FET-based sensor for detecting an ionic material, an ionic material detecting device including the FET-based sensor, and a method of detecting an ionic material using the FET-based sensor. The FET-based sensor includes: a sensing chamber including a reference electrode and a plurality of sensing FETs; and a reference chamber including a reference electrode and a plurality of reference FETs. The method includes: flowing a first solution into and out of the sensing chamber and the reference chamber of the FET-based sensor; flowing a second solution expected to contain an ionic material into and out of the sensing chamber while continuously flowing the first solution into and out of the reference chamber; measuring a current in a channel region between the source and drain of each of the sensing and reference FETs; and correcting the current of the sensing FETs.

    摘要翻译： 提供了一种用于检测离子材料的基于FET的传感器，包括基于FET的传感器的离子材料检测装置，以及使用基于FET的传感器检测离子材料的方法。 基于FET的传感器包括：感测室，包括参考电极和多个感测FET; 以及包括参考电极和多个参考FET的参考室。 该方法包括：使第一溶液流入和流出基于FET的传感器的感测室和参考室; 使预期含有离子材料的第二溶液流入和流出感测室，同时使第一溶液持续流入和移出参考室; 测量每个感测和参考FET的源极和漏极之间的沟道区域中的电流; 并校正感测FET的电流。

    NANOSENSOR AND METHOD OF MANUFACTURING SAME
    8.
    发明申请
    NANOSENSOR AND METHOD OF MANUFACTURING SAME 有权
    纳米传感器及其制造方法

    公开(公告)号：US20140202866A1

    公开(公告)日：2014-07-24

    申请号：US14224770

    申请日：2014-03-25

    申请人： Jeo-young SHIM ,  Tae-han Jeon ,  Dong-ho Lee ,  Hee-jeong Jeong ,  Seong-ho Cho

    发明人： Jeo-young SHIM ,  Tae-han Jeon ,  Dong-ho Lee ,  Hee-jeong Jeong ,  Seong-ho Cho

    IPC分类号： G01N27/447

    CPC分类号： G01N27/44791 ,  G01N33/48721

    摘要： A nanosensor may include a substrate that has a hole formed therein, a first insulating layer that is disposed on the substrate and has a nanopore formed therein, first and second electrodes that are disposed on the first insulating layer and are spaced apart from each other, first and second electrode pads that are disposed on the first and second electrodes, respectively, and a protective layer disposed on the first and second electrode pads. A method of manufacturing a nanosensor may include forming a first insulating layer, graphene, and a metal layer on a substrate, patterning the metal layer and the graphene, forming a protective layer on a portion of the graphene and the metal layer, exposing a portion of the graphene by removing a portion of the protective layer, forming a hole in the substrate, and forming a nanopore in the first insulating layer and the graphene to be connected to the hole.

    摘要翻译： 纳米传感器可以包括其中形成有孔的基板，设置在基板上并且在其中形成有纳米孔的第一绝缘层，设置在第一绝缘层上并彼此间隔开的第一和第二电极， 分别设置在第一和第二电极上的第一和第二电极焊盘以及设置在第一和第二电极焊盘上的保护层。 制造纳米传感器的方法可以包括在基板上形成第一绝缘层，石墨烯和金属层，图案化金属层和石墨烯，在石墨烯和金属层的一部分上形成保护层，将部分 通过去除保护层的一部分，在衬底中形成孔，并在第一绝缘层中形成纳米孔和与孔连接的石墨烯。

    NANOSENSOR AND METHOD OF DETECTING TARGET MOLECULE BY USING THE SAME
    10.
    发明申请
    NANOSENSOR AND METHOD OF DETECTING TARGET MOLECULE BY USING THE SAME 审中-公开
    用它们检测目标分子的纳米传感器和方法

    公开(公告)号：US20120326732A1

    公开(公告)日：2012-12-27

    申请号：US13475643

    申请日：2012-05-18

    申请人： Seong-ho CHO ,  Dong-ho LEE ,  Jeo-young SHIM

    发明人： Seong-ho CHO ,  Dong-ho LEE ,  Jeo-young SHIM

    IPC分类号： G01N27/04 ,  G01N27/02 ,  G01N27/22

    CPC分类号： G01N33/48721 ,  B82Y15/00

    摘要： The present disclosure includes a sensor and method for detecting a target molecule. In one instance, a sensor comprises a substrate including a hole, a first insulating layer located on the substrate and including a first nanopore corresponding to the hole, a first electrode, a second electrode, wherein the first electrode and the second electrode are located on a surface of the first insulating layer and are spaced apart by the first nanopore forming a nanogap, and a modulation unit configured to apply a unit input signal between the first electrode and the second electrode, wherein at least one unit input signal is applied as a target molecule passes through the nanogap.

    摘要翻译： 本公开内容包括用于检测靶分子的传感器和方法。 在一种情况下，传感器包括基板，其包括孔，位于基板上的第一绝缘层，并且包括对应于该孔的第一纳米孔，第一电极，第二电极，其中第一电极和第二电极位于 第一绝缘层的表面并且由形成纳米隙的第一纳米孔间隔开;以及调制单元，被配置为在第一电极和第二电极之间施加单位输入信号，其中至少一个单位输入信号作为 靶分子通过纳米隙。