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公开(公告)号：US12023158B2
公开(公告)日：2024-07-02
申请号：US16891426
申请日：2020-06-03
Applicant: MANN+HUMMEL GmbH
Inventor： Dagmar Winkler , Heike Rupp , Steffen Schuetz , Dietmar Talmon-Gros , Michael Fasold , Alfons-Alois Schwinghammer , Frank Bartel , Sascha Bauer , Patrick Nytz
IPC: A61B5/15 , A61B5/153 , A61M1/34 , A61M1/36 , B01D39/20 , B01D63/02 , B01D65/00 , B01D67/00 , B01D71/02 , G01N1/40 , G01N33/49 , A61M1/02 , B01L3/00
CPC classification number: A61B5/150755 , A61B5/15003 , A61B5/150229 , A61B5/150236 , A61B5/150251 , A61M1/34 , A61M1/3496 , A61M1/36 , A61M1/3633 , B01D63/0233 , B01D63/028 , B01D63/031 , B01D65/00 , B01D67/0088 , G01N1/4005 , G01N33/491 , A61B5/150244 , A61B5/150389 , A61B5/150503 , A61B5/153 , A61M1/0281 , A61M2205/3331 , B01D39/2068 , B01D2311/02 , B01D2313/10 , B01D2313/12 , B01D2313/24 , B01D2313/901 , B01D2323/04 , B01D2323/20 , B01L3/502 , B01L2300/0681 , B01L2400/0478 , B01L2400/0481 , G01N2001/4016 , G01N2201/0221 , G01N2201/0222 , G01N2800/22
Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.
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公开(公告)号：US11247175B2
公开(公告)日：2022-02-15
申请号：US16594363
申请日：2019-10-07
Applicant: MANN+HUMMEL GmbH
Inventor： Heike Rupp , Michael Fasold , Herbert Jainek , Sascha Bauer , Frank Ehlen , Stefan Kunze , Jasmin Sorg , Karlheinz Muenkel , Steffen Schuetz , Ulrich Dehnen
Abstract: A thermally sterilizable fluid filter (10) for concentrating substances contained in a fluid by way of micro-, nano- or ultrafiltration of the fluid, particularly for concentrating a pharmaceutical precursor and/or intermediate, in particular a vaccine, in a fluid. The fluid filter has a filter housing with a fluid inlet, a retentate outlet and a permeate outlet. A filter cartridge is arranged in the filter housing (12) and has a filter medium of a ceramic material and/or a ceramic composite material. The filter cartridge is held with axial play on the filter housing.
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公开(公告)号：US10561781B2
公开(公告)日：2020-02-18
申请号：US14967302
申请日：2015-12-12
Applicant: Mann+Hummel GMBH
Inventor： Dagmar Winkler , Heike Rupp , Claudio Weiss , Karlheinz Muenkel , Joachim Stinzendoerfer , Steffen Schuetz , Sascha Bauer , Frank Bartel , Alfons-Alois Schwinghammer , Michael Fasold , Dietmar Talmon-Gros , Norbert Strassenberger , Anton Rabanter
IPC: A61M1/34 , B01D63/00 , B01D63/02 , B01D61/28 , B01D61/14 , B01D61/24 , B01D61/18 , A61M1/36 , A61B5/15
Abstract: A blood filtering device has a filtration section with filter medium separating raw side and clean side. A first communication path connects raw side and a first variable blood reservoir volume; a second communication path connects raw side and a second variable blood reservoir volume coupled to a receptacle. When varying the first variable blood reservoir volume, blood contained therein flows through first communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through second communication path into the second variable blood reservoir volume. When varying the second variable blood reservoir volume, blood contained therein flows through second communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through first communication path into first variable blood reservoir volume.
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公开(公告)号：US20160129374A1
公开(公告)日：2016-05-12
申请号：US14981396
申请日：2015-12-28
Applicant: Mann+Hummel GMBH
Inventor： Dagmar Winkler , Heike Rupp , Steffen Schuetz , Karlheinz Muenkel , Joachim Stinzendoerfer
CPC classification number: B01D27/06 , A61M1/02 , B01D27/08 , B01D27/108 , G01N33/491
Abstract: A blood filtering device has a tubular housing with a tubular section and tubular housing volume. A filtration section with a filter medium separating a raw side from a clean side is arranged in the tubular housing. The filtration section is movable along the tubular section and movably sealed relative to the tubular housing. The filtration section separates the tubular housing volume into variable first and second tubular housing volumes. A first communication path extends between raw side and first tubular housing volume. A second communication path exits between raw side and second tubular housing volume. When moving the filtration section, blood in the first tubular housing volume flows through the first communication path to the raw side; blood plasma passes through the filter medium to the clean side; residual blood flows through the second communication path into the variable second tubular housing volume.
Abstract translation: 血液过滤装置具有管状壳体，其具有管状部分和管状容纳体积。 具有过滤介质的过滤部分布置在管状壳体中，该过滤介质将原料侧与干净侧分离。 过滤部分可沿管状部分移动并相对于管状壳体可移动地密封。 过滤部分将管状容器体积分成可变的第一和第二管状容器容积。 第一通信路径在原始侧和第一管状外壳体积之间延伸。 第二通信路径在原始侧和第二管状外壳体积之间离开。 当移动过滤部分时，第一管状容积容积中的血液流过第一连通路径至原始侧; 血浆通过过滤介质到干净的一面; 残余血液通过第二连通路径流入可变的第二管状容器容积。
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公开(公告)号：US20160106353A1
公开(公告)日：2016-04-21
申请号：US14983192
申请日：2015-12-29
Applicant: Mann+Hummel GMBH
Inventor： Steffen Schuetz , Dagmar Winkler , Heike Rupp
Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.
Abstract translation: 全血过滤装置设置有将过滤膜的进料体积和干净侧彼此分离的过滤膜。 进料量与第一进料侧开口和第二进料侧开口连通。 过滤膜具有孔径，其孔径确保过滤膜对血浆/血清的渗透性并保留血细胞。 第一供给侧开口可以联接到第一血泵，用于将血液从第一进料侧开口进入进料体积，使得血浆/血清渗透过滤膜，由过滤膜保留的血细胞从进料 体积通过第二进料侧开口。
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Patent Agency Ranking
6.发明申请CERAMIC WHOLE BLOOD HOLLOW FIBER MEMBRANE FILTER MEDIUM AND USE THEREOF FOR SEPARATIONG BLOOD PLASMA/SERUM FROM WHOLE BLOOD 审中-公开陶瓷全血中空纤维膜过滤介质及其用于分离血浆血浆/全血的血清公开(公告)号：US20160096148A1
公开(公告)日：2016-04-07
申请号：US14967860
申请日：2015-12-14
Applicant: Mann+Hummel GMBH
Inventor： Steffen Schuetz , Heike Rupp , Tobias Woerz , Dagmar Winkler , Kathrin Fischer , Frank Ehlen , Karlheinz Muenkel , Joachim Stinzendoerfer
CPC classification number: A61M1/34 , A61M1/3403 , A61M1/3496 , A61M2205/33 , A61M2205/3306 , B01D63/02 , B01D63/021 , B01D67/0041 , B01D67/0088 , B01D67/0093 , B01D69/02 , B01D69/08 , B01D69/081 , B01D69/087 , B01D71/024 , B01D71/025 , B01D71/027 , B01D71/028 , B01D71/42 , B01D71/68 , B01D71/70 , B01D2325/02 , B01D2325/04 , B01D2325/14 , B01D2325/20 , C08G77/00 , C08G77/04 , C08L83/00 , C08L83/04 , G01N33/491
Abstract: A whole blood hollow fiber membrane filter medium is provided with a ceramic material having pores of a pore size that ensures permeability to blood plasma or serum and its molecular components while blood cells are retained. The whole blood hollow fiber membrane filter medium is used for separating blood plasma from whole blood, wherein the blood plasma preferably shows no hemolysis.
Abstract translation: 全血中空纤维膜过滤介质设置有陶瓷材料，该陶瓷材料具有确保血液或血清及其分子成分的渗透性的孔径，同时保留血细胞。 全血中空纤维膜过滤介质用于从全血中分离血浆，其中血浆优选不显示溶血。
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公开(公告)号：US12023157B2
公开(公告)日：2024-07-02
申请号：US16891394
申请日：2020-06-03
Applicant: MANN+HUMMEL GmbH
Inventor： Dagmar Winkler , Heike Rupp , Steffen Schuetz , Dietmar Talmon-Gros , Michael Fasold , Alfons-Alois Schwinghammer , Frank Bartel , Sascha Bauer , Patrick Nytz
IPC: A61B5/15 , A61B5/153 , A61M1/02 , A61M1/34 , A61M1/36 , B01D39/20 , B01D63/02 , B01D65/00 , B01D67/00 , B01L3/00 , G01N1/40 , G01N33/49
CPC classification number: A61B5/150755 , A61B5/15003 , A61B5/150229 , A61B5/150236 , A61B5/150251 , A61M1/34 , A61M1/3496 , A61M1/36 , A61M1/3633 , B01D63/0233 , B01D63/028 , B01D63/031 , B01D65/00 , B01D67/0088 , G01N1/4005 , G01N33/491 , A61B5/150244 , A61B5/150389 , A61B5/150503 , A61B5/153 , A61M1/0281 , A61M2205/3331 , B01D39/2068 , B01D2311/02 , B01D2313/10 , B01D2313/12 , B01D2313/24 , B01D2313/901 , B01D2323/04 , B01D2323/20 , B01L3/502 , B01L2300/0681 , B01L2400/0478 , B01L2400/0481 , G01N2001/4016 , G01N2201/0221 , G01N2201/0222 , G01N2800/22
Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.
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公开(公告)号：US20200289041A1
公开(公告)日：2020-09-17
申请号：US16891394
申请日：2020-06-03
Applicant: MANN+HUMMEL GmbH
Inventor： Dagmar Winkler , Heike Rupp , Steffen Schuetz , Dietmar Talmon-Gros , Michael Fasold , Alfons-Alois Schwinghammer , Frank Bartel , Sascha Bauer , Patrick Nytz
IPC: A61B5/15 , A61M1/34 , B01D63/02 , B01D67/00 , G01N33/49 , B01D65/00 , G01N1/40 , A61M1/36 , B01D71/02
Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.
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公开(公告)号：US10687750B2
公开(公告)日：2020-06-23
申请号：US14983192
申请日：2015-12-29
Applicant: Mann+Hummel GMBH
Inventor： Steffen Schuetz , Dagmar Winkler , Heike Rupp , Dietmar Talmon-Gros , Michael Fasold , Alfons-Alois Schwinghammer , Frank Bartel , Sascha Bauer , Patrick Nytz
IPC: A61B5/15 , A61M1/34 , B01D63/02 , G01N33/49 , B01D65/00 , G01N1/40 , B01D71/02 , B01L3/00 , B01D39/20 , B01D67/00 , A61M1/36 , A61B5/153 , A61M1/02
Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.
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公开(公告)号：US10675399B2
公开(公告)日：2020-06-09
申请号：US14938381
申请日：2015-11-11
Applicant: Mann+Hummel GMBH
Inventor： Steffen Schuetz , Heike Rupp , Dagmar Winkler , Frank Ehlen
IPC: A61M1/34 , B01D63/02 , B01D69/02 , B01D69/08 , B01D67/00 , B01D71/26 , B01D71/34 , B01D71/40 , B01D71/42 , B01D71/68 , G01N1/40 , G01N33/49 , B01D71/56 , A61M1/36 , A61M1/16
Abstract: A whole blood hollow fiber membrane filter medium is made of a polymeric material having pores of a pore size that ensures permeability to blood plasma or serum but retains blood cells. The whole blood hollow fiber membrane filter medium is used for filtering a whole blood sample so that blood plasma or serum passes through the whole blood hollow fiber membrane filter medium and blood cells are retained. The obtained blood plasma shows no hemolysis.
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