公开(公告)号：US20060134793A1

公开(公告)日：2006-06-22

申请号：US11176757

申请日：2005-07-07

申请人： Marc Key ,  Scott Devore ,  Loren Bland ,  Uffe Lovborg

发明人： Marc Key ,  Scott Devore ,  Loren Bland ,  Uffe Lovborg

IPC分类号： G01N35/00

CPC分类号： G01N33/5306 ,  G01N1/30 ,  G01N33/54393 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/2575

摘要： The present invention concerns a method and apparatus for automatic staining or other processing of a biological sample on a slide, perhaps robotically, by applying predetermined amounts of reagents in a predetermined sequence according to a processing protocol, the processing including pre-treatment steps, under the control of an adaptive processing control system. Further provided is a method of antigen retrieval, the method comprising contacting, within a heated processing tank of an automated staining apparatus, at least one biological sample with at least one composition for antigen retrieval comprising at least one chelating agent, at least one detergent and at least 50% by volume of at least one liquid that facilitates antigen retrieval.

摘要翻译： 本发明涉及一种用于通过根据处理方案以预定顺序施加预定量的试剂，可能机器人地在载玻片上自动染色或其它处理生物样品的方法和装置，该处理包括预处理步骤 自适应处理控制系统的控制。 进一步提供的是一种抗原回收方法，该方法包括在加热处理罐内自动染色装置的至少一个生物样品与至少一种用于抗原回收的组合物接触，所述组合物用于抗原回收，包括至少一种螯合剂，至少一种洗涤剂和 至少50体积％的至少一种促进抗原回收的液体。

公开(公告)号：US20060105359A1

公开(公告)日：2006-05-18

申请号：US11156760

申请日：2005-06-20

申请人： John Favuzzi ,  Kristopher Buchanan ,  Michael Barber ,  Loren Bland ,  Dawn Rohrbacker ,  Robert Clark ,  Gordon Feingold ,  Benno Guggenheimer ,  Marc Key ,  Merritt Martin ,  Robert Lathrop ,  Jeffery Rau ,  Jonathan Sweda ,  Douglas Sweet ,  John Van Bosch ,  Lars Winther ,  Rosanne Welcher

发明人： John Favuzzi ,  Kristopher Buchanan ,  Michael Barber ,  Loren Bland ,  Dawn Rohrbacker ,  Robert Clark ,  Gordon Feingold ,  Benno Guggenheimer ,  Marc Key ,  Merritt Martin ,  Robert Lathrop ,  Jeffery Rau ,  Jonathan Sweda ,  Douglas Sweet ,  John Van Bosch ,  Lars Winther ,  Rosanne Welcher

IPC分类号： C12Q1/68 ,  G06F19/00 ,  C12M1/34

CPC分类号： G01N35/0092 ,  B01L3/508 ,  B01L7/00 ,  B01L9/06 ,  B01L2200/025 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/0822 ,  B01L2300/1822 ,  G01N1/312 ,  G01N35/00029 ,  G01N35/00871 ,  G01N35/0095 ,  G01N35/0099 ,  G01N35/1002 ,  G01N35/1004 ,  G01N35/1011 ,  G01N2035/00356 ,  G01N2035/00366 ,  G01N2035/00445 ,  G01N2035/00455 ,  G01N2035/00534 ,  G01N2035/00633 ,  G01N2035/00673 ,  G01N2035/00752 ,  G01N2035/00861 ,  G01N2035/00881 ,  G01N2035/102 ,  G01N2035/1058 ,  Y02A90/26 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/12 ,  Y10T436/2575

摘要： The present invention concerns a method and apparatus for automatic processing a biological sample on a carrier, perhaps robotically, by applying predetermined amounts of reagents in a predetermined sequence according to a processing protocol, the processing including pre-treatment steps, under the control of an adaptive processing control system using a sample process parameter input that may be independent and an independent process parameter memory that does not interrupt process operation when being used, such that samples may be added or removed without interrupting the processing of other samples. Also included is an image capture function for sample and reagent identification and process monitoring, as well as temperature regulation and environmental control functions.

摘要翻译： 本发明涉及一种用于通过根据处理方案以预定顺序施加预定量的试剂来自动地处理载体上的生物样品的方法和装置，所述方法和装置可以机器人地处理，所述处理包括预处理步骤，在 自适应处理控制系统使用可以是独立的样本过程参数输入和在使用时不中断处理操作的独立过程参数存储器，使得可以添加或移除样本而不中断其他样本的处理。 还包括用于样品和试剂识别和过程监测以及温度调节和环境控制功能的图像捕获功能。

公开(公告)号：US20060040341A1

公开(公告)日：2006-02-23

申请号：US11168987

申请日：2005-06-28

申请人： Loren Bland ,  Marc Key ,  Lars Winther ,  David Stanforth ,  Martin Lindberg

发明人： Loren Bland ,  Marc Key ,  Lars Winther ,  David Stanforth ,  Martin Lindberg

IPC分类号： G01N1/30 ,  G01N33/48 ,  G06F19/00 ,  G01N33/50

CPC分类号： G01N1/30 ,  B01L3/545 ,  B01L2300/023 ,  B01L2300/024 ,  B01L2300/0822 ,  G01N1/312 ,  G01N35/00732 ,  G01N2035/00782 ,  Y10T436/255

摘要： There is disclosed a method of pre-treatment and staining, according to a protocol, of a biological sample disposed upon the surface of a carrier, the method comprising the step of recording at least one parameter relating to at least one protocol step in a non-volatile memory located either upon or within the carrier or a device incorporating the carrier. Also disclosed is a device comprising: a non-volatile memory; a surface of the device adapted to carry a biological sample; and communications means electrically coupled to the memory for enabling data transmission to or from an external apparatus. Also disclosed is a method of controlling processing of a biological sample disposed upon a carrier, comprising: providing, upon or within the carrier or an apparatus holding the carrier, a non-volatile memory having information relating to sample processing priority or protocol; reading the information; and scheduling the processing based upon the information.

公开(公告)号：US08583746B1

公开(公告)日：2013-11-12

申请号：US12125746

申请日：2008-05-22

申请人： Daniel D'Agruma ,  Chris Phillips ,  Nicholas Burwell ,  Loren Bland

发明人： Daniel D'Agruma ,  Chris Phillips ,  Nicholas Burwell ,  Loren Bland

IPC分类号： G06F15/16 ,  H04M3/42

CPC分类号： H04L51/10 ,  H04L51/00 ,  H04L51/14 ,  H04L51/32 ,  H04L51/34 ,  H04L67/02 ,  H04L67/10 ,  H04L67/42 ,  H04M3/42153 ,  H04M3/42382 ,  H04M7/0024 ,  H04M2203/655

摘要： Communication systems and methods are described. In an illustrative embodiment, embeddable code is provided to a user to embed on a user web page. A communication request is received from a visitor via a user interface displayed on the user web page, the user interface including an address field configured to receive from the visitor an address associated with the visitor, and a text entry field configured to receive a text message from the visitor, wherein the user interface is generated at least in part by the code. If the visitor enters a phone address into the address field, a determination is made as to whether the phone address is valid at least partly in response to a first action by the visitor. If the visitor enters text into the text entry field, the text is transmitted to the user at least partly in response to a second action by the visitor.

摘要翻译： 描述了通信系统和方法。 在说明性实施例中，可嵌入代码被提供给用户嵌入在用户网页上。 通过用户网页上显示的用户界面从访问者接收到通信请求，用户界面包括被配置为从访问者接收与该访问者相关联的地址的地址字段以及被配置为接收文本消息的文本输入字段 其中所述用户界面至少部分地由所述代码生成。 如果访客在地址字段中输入电话地址，则至少部分地响应于访问者的第一个动作来确定电话地址是否有效。 如果访问者将文本输入到文本输入字段中，则该文本至少部分地响应于访问者的第二个动作被发送给用户。