High density plate filler
    1.
    发明申请
    High density plate filler 审中-公开
    高密度板填料

    公开(公告)号:US20070014694A1

    公开(公告)日:2007-01-18

    申请号:US11086800

    申请日:2005-03-22

    IPC分类号: B01L3/02

    摘要: A filling apparatus for filling a microplate. The microplate having a plurality of wells each sized to receive an assay. The filling apparatus can comprise an assay input layer having a first surface and an opposing second surface. The assay input layer can comprise an assay input port extending from the first surface to the second surface and at least one pressure nodule extending from the second surface. An output layer can comprise a plurality of staging capillaries each having an inlet and an outlet. A intermediate layer can be disposed between the assay input layer and the output layer. The intermediate layer can be flexible and comprise a plurality of microfluidic channels and a flow aperture being in fluid communication with the assay input port and the plurality of microfluidic channels. The assay input layer can be moveable relative to the intermediate layer such that the at least one pressure nodule engages the intermediate layer to apply a clamping force on at least a portion of one of the plurality of microfluidic channels to reduce flow of the assay therethrough.

    摘要翻译: 一种用于填充微板的填充装置。 微量培养板具有多个孔,每个孔的大小用于接受测定。 填充装置可以包括具有第一表面和相对的第二表面的测定输入层。 测定输入层可以包括从第一表面延伸到第二表面的测定输入端口和从第二表面延伸的至少一个压力结节。 输出层可以包括多个具有入口和出口的分段毛细管。 中间层可以设置在测定输入层和输出层之间。 中间层可以是柔性的并且包括多个微流体通道,并且流动孔与测定输入端口和多个微流体通道流体连通。 测定输入层可以相对于中间层移动,使得至少一个压力结节接合中间层,以在多个微流体通道之一的至少一部分上施加夹紧力,以减少测定的流动。

    High density plate filler
    4.
    发明申请
    High density plate filler 有权
    高密度板填料

    公开(公告)号:US20050232820A1

    公开(公告)日:2005-10-20

    申请号:US11086271

    申请日:2005-03-22

    摘要: A filling apparatus for filling a microplate. The microplate having a plurality of wells each sized to receive an assay. The filling apparatus can comprise an assay input layer having a first surface and an opposing second surface. The assay input layer can comprise an assay input port extending from the first surface to the second surface, a venting manifold formed in the second surface, and a vent hole in fluid communication with the venting manifold and atmosphere. An output layer can comprise a plurality of staging capillaries each having an inlet and an outlet. A venting layer can be disposed between the assay input layer and the output layer. The venting layer can comprise a plurality of microfluidic channels, a flow aperture being in fluid communication with the assay input port and the plurality of microfluidic channels, and a plurality of vent apertures each in fluid communication with at least one of the plurality of staging capillaries. Two or more of the plurality of vent apertures can be in fluid communication with the venting manifold.

    摘要翻译: 一种用于填充微板的填充装置。 微量培养板具有多个孔,每个孔的大小用于接受测定。 填充装置可以包括具有第一表面和相对的第二表面的测定输入层。 测定输入层可以包括从第一表面延伸到第二表面的测定输入端口,形成在第二表面中的排气歧管以及与排气歧管和气氛流体连通的通气孔。 输出层可以包括多个具有入口和出口的分段毛细管。 排气层可以设置在测定输入层和输出层之间。 通气层可以包括多个微流体通道,与测定输入端口和多个微流体通道流体连通的流动孔,以及多个通气孔,每个通气孔与多个分级毛细管中的至少一个流体连通 。 多个通气孔中的两个或更多个可以与排气歧管流体连通。