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公开(公告)号：US20090227472A1
公开(公告)日：2009-09-10
申请号：US12405170
申请日：2009-03-16
申请人： John R. Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
发明人： John R. Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
IPC分类号： C40B40/06
CPC分类号： B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00382 , B01J2219/005 , B01J2219/00511 , B01J2219/00524 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00704 , B01J2219/0072 , B01J2219/00722 , C40B40/06 , G01N33/54393
摘要： The invention relates to sensor compositions comprising a composite array of individual arrays, to allow for simultaneous processing of a number of samples. The invention further provides methods of making and using the composite arrays. The invention further provides a hybridization chamber for use with a composite array.
摘要翻译： 本发明涉及包括单独阵列的复合阵列的传感器组合物，以允许同时处理多个样品。 本发明还提供了制备和使用复合阵列的方法。 本发明还提供了一种与复合阵列一起使用的杂交室。
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公开(公告)号：US08628952B2
公开(公告)日：2014-01-14
申请号：US12405162
申请日：2009-03-16
申请人： John R. Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
发明人： John R. Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
CPC分类号： B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00382 , B01J2219/005 , B01J2219/00511 , B01J2219/00524 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00704 , B01J2219/0072 , B01J2219/00722 , C40B40/06 , G01N33/54393
摘要： The invention relates to sensor compositions comprising a composite array of individual arrays, to allow for simultaneous processing of a number of samples. The invention further provides methods of making and using the composite arrays. The invention further provides a hybridization chamber for use with a composite array.
摘要翻译： 本发明涉及包括单独阵列的复合阵列的传感器组合物，以允许同时处理多个样品。 本发明还提供了制备和使用复合阵列的方法。 本发明还提供了一种与复合阵列一起使用的杂交室。
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公开(公告)号：US20090298716A1
公开(公告)日：2009-12-03
申请号：US12419218
申请日：2009-04-06
申请人： John R. Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
发明人： John R. Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
IPC分类号： C40B50/14
CPC分类号： B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00382 , B01J2219/005 , B01J2219/00511 , B01J2219/00524 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00704 , B01J2219/0072 , B01J2219/00722 , C40B40/06 , G01N33/54393
摘要： The invention relates to sensor compositions comprising a composite array of individual arrays, to allow for simultaneous processing of a number of samples. The invention further provides methods of making and using the composite arrays. The invention further provides a hybridization chamber for use with a composite array.
摘要翻译： 本发明涉及包括单独阵列的复合阵列的传感器组合物，以允许同时处理多个样品。 本发明还提供了制备和使用复合阵列的方法。 本发明还提供了一种与复合阵列一起使用的杂交室。
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公开(公告)号：US06429027B1
公开(公告)日：2002-08-06
申请号：US09256943
申请日：1999-02-24
IPC分类号： G01N33543
CPC分类号： G01N33/543 , B01J2219/00315 , B01J2219/00317 , B01J2219/00382 , B01J2219/005 , B01J2219/00585 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , C40B60/14 , G01N33/54313 , G01N33/54393 , Y10S977/924
摘要： The invention relates to compositions and methods for decoding microsphere array sensors.
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公开(公告)号：US20090221450A1
公开(公告)日：2009-09-03
申请号：US12405163
申请日：2009-03-16
申请人： John R Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
发明人： John R Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
IPC分类号： C40B50/18
CPC分类号： B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00382 , B01J2219/005 , B01J2219/00511 , B01J2219/00524 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00704 , B01J2219/0072 , B01J2219/00722 , C40B40/06 , G01N33/54393
摘要： The invention relates to sensor compositions comprising a composite array of individual arrays, to allow for simultaneous processing of a number of samples. The invention further provides methods of making and using the composite arrays. The invention further provides a hybridization chamber for use with a composite array.
摘要翻译： 本发明涉及包括单独阵列的复合阵列的传感器组合物，以允许同时处理多个样品。 本发明还提供了制备和使用复合阵列的方法。 本发明还提供了一种与复合阵列一起使用的杂交室。
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公开(公告)号：US06858394B1
公开(公告)日：2005-02-22
申请号：US09473904
申请日：1999-12-28
IPC分类号： G01N33/53 , C12M1/00 , C12N15/09 , C40B40/02 , C40B50/06 , C40B60/14 , G01N33/15 , G01N33/483 , G01N33/50 , G01N33/543 , G01N33/566 , G01N37/00 , G01N33/00
CPC分类号： G01N33/543 , B01J2219/00315 , B01J2219/00317 , B01J2219/00382 , B01J2219/005 , B01J2219/00585 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , C40B60/14 , G01N33/54313 , G01N33/54393 , Y10S977/924
摘要： The invention relates to sensor compositions comprising a composite array of individual arrays, to allow for simultaneous processing of a number of samples. The invention further provides methods of making and using the composite arrays.
摘要翻译： 本发明涉及包括单独阵列的复合阵列的传感器组合物，以允许同时处理多个样品。 本发明还提供了制备和使用复合阵列的方法。
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公开(公告)号：US20090215649A1
公开(公告)日：2009-08-27
申请号：US12405162
申请日：2009-03-16
申请人： John R. Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
发明人： John R. Stuelpnagel , Mark S. Chee , Steven R. Auger , Gan G. Wang , Laura S. Casas , Shawn Christopher Baker , Robert C. Kain
CPC分类号： B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00382 , B01J2219/005 , B01J2219/00511 , B01J2219/00524 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00704 , B01J2219/0072 , B01J2219/00722 , C40B40/06 , G01N33/54393
摘要： The invention relates to sensor compositions comprising a composite array of individual arrays, to allow for simultaneous processing of a number of samples. The invention further provides methods of making and using the composite arrays. The invention further provides a hybridization chamber for use with a composite array.
摘要翻译： 本发明涉及包括单独阵列的复合阵列的传感器组合物，以允许同时处理多个样品。 本发明还提供了制备和使用复合阵列的方法。 本发明还提供了一种与复合阵列一起使用的杂交室。
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公开(公告)号：US06998274B2
公开(公告)日：2006-02-14
申请号：US10194912
申请日：2002-07-12
IPC分类号： G01N33/543 , G01N33/53 , C12M1/34
CPC分类号： G01N33/543 , B01J2219/00315 , B01J2219/00317 , B01J2219/00382 , B01J2219/005 , B01J2219/00585 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , C40B60/14 , G01N33/54313 , G01N33/54393 , Y10S977/924
摘要： The invention relates to compositions and methods for decoding microsphere array sensors.
摘要翻译： 本发明涉及用于解码微球阵列传感器的组合物和方法。
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公开(公告)号：US08486625B2
公开(公告)日：2013-07-16
申请号：US12212585
申请日：2008-09-17
CPC分类号： C12Q1/6837 , C12Q1/6858 , C12Q1/6874 , C12Q2535/131 , C12Q2525/191 , C12Q2531/137 , C12Q2563/149
摘要： The present invention is directed to methods and compositions for the use of microsphere arrays to detect and quantify a number of nucleic acid reactions. The invention finds use in genotyping, i.e. the determination of the sequence of nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs). Similarly, the invention finds use in the detection and quantification of a nucleic acid target using a variety of amplification techniques, including both signal amplification and target amplification. The methods and compositions of the invention can be used in nucleic acid sequencing reactions as well. All applications can include the use of adapter sequences to allow for universal arrays.
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公开(公告)号：US07604996B1
公开(公告)日：2009-10-20
申请号：US09642068
申请日：2000-08-18
申请人： John R. Stuelpnagel , Mark S. Chee
发明人： John R. Stuelpnagel , Mark S. Chee
CPC分类号： C12N15/1093 , C12Q1/6806 , C12Q1/6834 , C12Q1/6837 , C12Q1/686 , C12Q1/6876 , G11C7/1048 , H03K19/0966 , Y10S977/792 , C12Q2525/197 , C12Q2523/107
摘要： The present invention is directed to methods and compositions for generating a pool of oligonucleotides. The invention finds use in preparing a population or subpopulations of oligonucleotides in solution. The pool of oligonucleotides finds use in a variety of nucleic acid detection and/or amplification assays.
摘要翻译： 本发明涉及用于产生寡核苷酸库的方法和组合物。 本发明用于制备溶液中寡核苷酸的群体或亚群。 寡核苷酸库可用于各种核酸检测和/或扩增测定。
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